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The map label for this gene is hutC [H]

Identifier: 77748599

GI number: 77748599

Start: 1892915

End: 1893619

Strand: Direct

Name: hutC [H]

Synonym: XAC1640

Alternate gene names: 77748599

Gene position: 1892915-1893619 (Clockwise)

Preceding gene: 21242389

Following gene: 21242395

Centisome position: 36.57

GC content: 67.8

Gene sequence:

>705_bases
TTGCATCAGCGCATCCGCCAGGATCTGGAACAACGCATCCATAGCGGCGACTGGCCGCCCGGGCACCGCGTGCCGCCCGA
GCATGAGTTGATGGCGCAGTACGGCTGCTCGCGCATGACCGTGAACAAGGTGCTCGGCTTGCTGGCCGATGCCGGCATGA
TCGAACGCCGCCGCCGTACCGGTTCATTCGTGGCACGGCAGCACCCGCATCTGGAACAGGTGGCGCTTTCGATCCCGGAC
ATCGAAGTGGAAATGACCACGCGCGGCCATGCGTACCGGTTCTCTTTGTTGTCGCGGCAGCTGCGCAACGTGCGGCAGCG
CGTGCCGCAGGAACGTGCGCTGGGCAGCACCGGCAAGGTGCTGGAATTGCAGAGCGTGCACCTGGCCGACGGCCGCCCGT
TTGCGCTGGAGCACCGCGTGATCGATATCGCCACCGTGCCCGACGCATTGGACCAGCCGTTCACGGAGGTGGCGCCGGGC
AGCTGGTTATTGCGCAACGTGCCATGGACGCGCGCCGAGCACCGCATCAGCGCTGCCAGTGCCGATGCCGCGCAGGCCGA
GCAGCTCCAGGCGGACGATGGCGCGGCCTGCCTGGTGATCGACCGCCACACCTGGCGCGGGGACCTGCCGGTCACCTACG
TGCGCCAGATGTTTCTAGGCGGGTCGTACGATCTGGTGGCGCGGTTCGCGCCGGGGCTGCGCTGA

Upstream 100 bases:

>100_bases
TGCTGGCGCACGCTGCCGACCATGTGGCATGCCGATTGAATAGCCGCTCTTTCCGGAGACCCGCGCGTTGAACGCCATCA
CCACCATCGTGCCTGGCACC

Downstream 100 bases:

>100_bases
GGTGATGTCGGCAGGCGACGGACGCTACCGCAGCGCTCAAGTCGCCGGGGATTGTTGGCTGAACGGTTATCGGCCGTGTT
GAAGTCGCACGCCAAGATGG

Product: histidine utilization repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MHQRIRQDLEQRIHSGDWPPGHRVPPEHELMAQYGCSRMTVNKVLGLLADAGMIERRRRTGSFVARQHPHLEQVALSIPD
IEVEMTTRGHAYRFSLLSRQLRNVRQRVPQERALGSTGKVLELQSVHLADGRPFALEHRVIDIATVPDALDQPFTEVAPG
SWLLRNVPWTRAEHRISAASADAAQAEQLQADDGAACLVIDRHTWRGDLPVTYVRQMFLGGSYDLVARFAPGLR

Sequences:

>Translated_234_residues
MHQRIRQDLEQRIHSGDWPPGHRVPPEHELMAQYGCSRMTVNKVLGLLADAGMIERRRRTGSFVARQHPHLEQVALSIPD
IEVEMTTRGHAYRFSLLSRQLRNVRQRVPQERALGSTGKVLELQSVHLADGRPFALEHRVIDIATVPDALDQPFTEVAPG
SWLLRNVPWTRAEHRISAASADAAQAEQLQADDGAACLVIDRHTWRGDLPVTYVRQMFLGGSYDLVARFAPGLR
>Mature_234_residues
MHQRIRQDLEQRIHSGDWPPGHRVPPEHELMAQYGCSRMTVNKVLGLLADAGMIERRRRTGSFVARQHPHLEQVALSIPD
IEVEMTTRGHAYRFSLLSRQLRNVRQRVPQERALGSTGKVLELQSVHLADGRPFALEHRVIDIATVPDALDQPFTEVAPG
SWLLRNVPWTRAEHRISAASADAAQAEQLQADDGAACLVIDRHTWRGDLPVTYVRQMFLGGSYDLVARFAPGLR

Specific function: Repressor which binds to the hutP region in the histidine utilization (hut) operon. It blocks the expression of all the hut genes in the absence of inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010248
- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 26381; Mature: 26381

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQRIRQDLEQRIHSGDWPPGHRVPPEHELMAQYGCSRMTVNKVLGLLADAGMIERRRRT
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHH
GSFVARQHPHLEQVALSIPDIEVEMTTRGHAYRFSLLSRQLRNVRQRVPQERALGSTGKV
HHHHHHCCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCE
LELQSVHLADGRPFALEHRVIDIATVPDALDQPFTEVAPGSWLLRNVPWTRAEHRISAAS
EEEEEEEECCCCCEEECCEEEEEEECCHHHCCCHHHHCCCCCEECCCCCCHHHHHHHHHC
ADAAQAEQLQADDGAACLVIDRHTWRGDLPVTYVRQMFLGGSYDLVARFAPGLR
CCHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCC
>Mature Secondary Structure
MHQRIRQDLEQRIHSGDWPPGHRVPPEHELMAQYGCSRMTVNKVLGLLADAGMIERRRRT
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHH
GSFVARQHPHLEQVALSIPDIEVEMTTRGHAYRFSLLSRQLRNVRQRVPQERALGSTGKV
HHHHHHCCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCE
LELQSVHLADGRPFALEHRVIDIATVPDALDQPFTEVAPGSWLLRNVPWTRAEHRISAAS
EEEEEEEECCCCCEEECCEEEEEEECCHHHCCCHHHHCCCCCEECCCCCCHHHHHHHHHC
ADAAQAEQLQADDGAACLVIDRHTWRGDLPVTYVRQMFLGGSYDLVARFAPGLR
CCHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]