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The map label for this gene is luxQ [H]

Identifier: 77748572

GI number: 77748572

Start: 1455567

End: 1456439

Strand: Direct

Name: luxQ [H]

Synonym: XAC1273

Alternate gene names: 77748572

Gene position: 1455567-1456439 (Clockwise)

Preceding gene: 21242025

Following gene: 21242027

Centisome position: 28.12

GC content: 62.2

Gene sequence:

>873_bases
ATGAATTCAACCACCGATCTGCCGGCAGCCGAGATGGCTGAACTTGAAAGCCTGCGCCAGCAGAACCAGGCCTTGCGCGA
AGAGCTGGAAGAAACCAACCAAGGCGTGCTGGCCTTGTATGCCGAGCTCGACCAGCAGGCCGAACAGCTGCGCGACGTGT
CCGAACTCAAGAGCCGCTTTCTGTCGTACATGAGCCACGAGTTCCGTACCCCGCTAGGCTCGATCCTGAGCATCACCCGG
CTGCTGGAGGACGGCATGGACGGGCCGCTCAACGCCGAGCAGCTCAAGCAGGTGCGCTTTGTCAGCGGTTCGGCGCGTGA
GCTCACCGAGATGGTGGACGACCTGCTGGACCTGGCCAAGATCGAGGCCGGGCGCATCACCATCTCGCCGGGCTGGTTCG
ACCTGATGGACCTGTTCGCGGCGCTGCGCGGCATGTTCCGGCCGCTCACCGATATGGGCAGTACCACGCTGATCTTCGAG
GATCCGCCGGTACTGCCGATGCTCTACACCGACGACAAGAAGCTGGCGCAGATCCTGCGCAATTTCATATCCAATGCGCT
CAAGTTCACCCCGCAGGGACAGGTGCGCGTGTTTGCGCAGCTGGAAGGCGACAGCCATGTACGCTTTGGCGTGCAGGACA
CTGGCATCGGCATTCCGGCCGAGCTTCACGAGGCCTTGTTCGAAGATTTCGTACAGGTGGACTCGCCGCTGCAAAAACGC
CTGACCGGCACCGGCCTGGGGTTGTCGATCTGCAAACGGTTCGCCGAATTGCTGGGCGGCCGGGTGGGGATCAACAGCGT
GGTCGGGCAGGGTTCTGAATTTTACGTGGTGCTGCCGGTGACCCTGGCAGCGGAGGAGACACGTGGGCAGTAA

Upstream 100 bases:

>100_bases
TGTCGCGCCATCCACGCATCATTGCCGCAGTGCTGGCACGCGATTACGCGCGCGGCCGCGACGATTGCTGCGTGTTCGTC
ATGCGCTTGGGAGGCATGCA

Downstream 100 bases:

>100_bases
GCACCACATTCTGGTCGTCGACGACAACGCGGTGACGCGTTATTCGGTGCGGCGCGTGCTCGAACACCATCAGTTCGTGA
TCGAAGAAGCCGGCACCGGG

Product: two-component system sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MNSTTDLPAAEMAELESLRQQNQALREELEETNQGVLALYAELDQQAEQLRDVSELKSRFLSYMSHEFRTPLGSILSITR
LLEDGMDGPLNAEQLKQVRFVSGSARELTEMVDDLLDLAKIEAGRITISPGWFDLMDLFAALRGMFRPLTDMGSTTLIFE
DPPVLPMLYTDDKKLAQILRNFISNALKFTPQGQVRVFAQLEGDSHVRFGVQDTGIGIPAELHEALFEDFVQVDSPLQKR
LTGTGLGLSICKRFAELLGGRVGINSVVGQGSEFYVVLPVTLAAEETRGQ

Sequences:

>Translated_290_residues
MNSTTDLPAAEMAELESLRQQNQALREELEETNQGVLALYAELDQQAEQLRDVSELKSRFLSYMSHEFRTPLGSILSITR
LLEDGMDGPLNAEQLKQVRFVSGSARELTEMVDDLLDLAKIEAGRITISPGWFDLMDLFAALRGMFRPLTDMGSTTLIFE
DPPVLPMLYTDDKKLAQILRNFISNALKFTPQGQVRVFAQLEGDSHVRFGVQDTGIGIPAELHEALFEDFVQVDSPLQKR
LTGTGLGLSICKRFAELLGGRVGINSVVGQGSEFYVVLPVTLAAEETRGQ
>Mature_290_residues
MNSTTDLPAAEMAELESLRQQNQALREELEETNQGVLALYAELDQQAEQLRDVSELKSRFLSYMSHEFRTPLGSILSITR
LLEDGMDGPLNAEQLKQVRFVSGSARELTEMVDDLLDLAKIEAGRITISPGWFDLMDLFAALRGMFRPLTDMGSTTLIFE
DPPVLPMLYTDDKKLAQILRNFISNALKFTPQGQVRVFAQLEGDSHVRFGVQDTGIGIPAELHEALFEDFVQVDSPLQKR
LTGTGLGLSICKRFAELLGGRVGINSVVGQGSEFYVVLPVTLAAEETRGQ

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=35.9504132231405, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=34.4961240310078, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789149, Length=284, Percent_Identity=31.3380281690141, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI87081816, Length=285, Percent_Identity=34.3859649122807, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788713, Length=264, Percent_Identity=28.7878787878788, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=25.3061224489796, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87082128, Length=261, Percent_Identity=28.735632183908, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=224, Percent_Identity=26.7857142857143, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786600, Length=247, Percent_Identity=28.3400809716599, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786783, Length=244, Percent_Identity=27.4590163934426, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=27.8761061946903, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790300, Length=261, Percent_Identity=29.1187739463602, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790346, Length=267, Percent_Identity=26.9662921348315, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=23.6734693877551, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=75, Percent_Identity=45.3333333333333, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 32153; Mature: 32153

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTTDLPAAEMAELESLRQQNQALREELEETNQGVLALYAELDQQAEQLRDVSELKSRF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSYMSHEFRTPLGSILSITRLLEDGMDGPLNAEQLKQVRFVSGSARELTEMVDDLLDLAK
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IEAGRITISPGWFDLMDLFAALRGMFRPLTDMGSTTLIFEDPPVLPMLYTDDKKLAQILR
HCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCHHHHHHHH
NFISNALKFTPQGQVRVFAQLEGDSHVRFGVQDTGIGIPAELHEALFEDFVQVDSPLQKR
HHHHHHHCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHH
LTGTGLGLSICKRFAELLGGRVGINSVVGQGSEFYVVLPVTLAAEETRGQ
HCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEEEEECHHCCCC
>Mature Secondary Structure
MNSTTDLPAAEMAELESLRQQNQALREELEETNQGVLALYAELDQQAEQLRDVSELKSRF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSYMSHEFRTPLGSILSITRLLEDGMDGPLNAEQLKQVRFVSGSARELTEMVDDLLDLAK
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IEAGRITISPGWFDLMDLFAALRGMFRPLTDMGSTTLIFEDPPVLPMLYTDDKKLAQILR
HCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCHHHHHHHH
NFISNALKFTPQGQVRVFAQLEGDSHVRFGVQDTGIGIPAELHEALFEDFVQVDSPLQKR
HHHHHHHCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHH
LTGTGLGLSICKRFAELLGGRVGINSVVGQGSEFYVVLPVTLAAEETRGQ
HCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA