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The map label for this gene is cvgSY [C]

Identifier: 21242027

GI number: 21242027

Start: 1456429

End: 1458384

Strand: Direct

Name: cvgSY [C]

Synonym: XAC1274

Alternate gene names: 21242027

Gene position: 1456429-1458384 (Clockwise)

Preceding gene: 77748572

Following gene: 77748574

Centisome position: 28.14

GC content: 65.34

Gene sequence:

>1956_bases
GTGGGCAGTAAGCACCACATTCTGGTCGTCGACGACAACGCGGTGACGCGTTATTCGGTGCGGCGCGTGCTCGAACACCA
TCAGTTCGTGATCGAAGAAGCCGGCACCGGGACCGAGGGGCTTGCGAAACTGGCCACGCAGACGTTTTCTGCGGTGTTGC
TGGACGTCAACCTGCCGGACATGAGTGGCTTCGACATCGTGCGGACGCTGCGTGCCGAGCCGCGCACCGCATTGCTCCCG
GTGGTGCATGTCTCGGCGGCCTCGATCGCCACCGGCGACATGATCACCGGGCTGGATGCCGGCGCCGACGCCTACCTGAT
CCATCCGGTCGACCCCAACGTATTGCTGGCCACGTTGCGCACCCTACTGCGCGCACGCCGCGCCGAGGAGGCGCTGCGGA
TCAGCGAGGCGCGTTTCCGCGAAATCTTCGAACACATCAGCGCGCCGATTGCGGTGGTGGATGCCAACCTGCACATGCAC
GAGGCCAATGCCGCGTTCCAGCGTTTGATCGGGAGCGCCACGCCCGGCGCCGCGATCCACGCCGCCGGGTTGGATCAGGC
CGCCGCTGTGCATGCCCTGACCACTGCGTTGGCGCAGCGCGAGCGCTGGAGCGGCACCTTGTCGCTGCTGCGCGATGGCA
AGCTCTGCGAAACCGAATGGCGGGTGTCGCCCTACCGCGAGCCGGATCTGGGGCTGTTGCTGGTGGAAGACGTCACCGAG
CAGCGCCTGCGCGAGCGCGAGCAGCGCCAGGAACTGGATACCGCCACCAGCGAGCTCGCGCATCAGATCGCGCAGCGCCA
GCACACCGAAATCCAGCTGCTGCAGGCGCAAAAGATGGAAGCGCTGGGCAAGCTCACCGGTGGCATCGCGCACGACTTCA
ACAACCTGCTGACCAGCATCATCTCCGGGCTGGACATGATCCAGCTCGCAGTGGAATCCAACCGCATCGAACGGGTGCCG
CGCCTGGCCGAGATCGCCACCGGCTCTGCGCACCGCGCCGCCGCGCTGACCCAGCGCATGCTGGCGTTCGCACGCAAGCA
ATCGCTGGACGCGCAACCGTTCGACGTCAACATCCGCGTGCGTTCGCTGGAAGACATGCTGCAGCGCTCGATCGGCGAAA
ACATCGCGCTGGAGCTGGAGCTTGCATCCACGCCGCTGGTGGCCATAGCCGATGCCAACCAGCTCGAAAACGTGGTGCTC
AACCTGGTCATCAATGCGCGCGACGCATTGAAAGGGCAGGGCACCATCCGCATCCAGAGCGCGGCCTACACTGCGCACAA
CGATCCGGAACTGGACGACGGCGACTATGTCGCGGTGAAGGTGATCGACAACGGGAGTGGGATCGAGCCGGCCATTCTCG
ACCAGGTGTTCGAACCGTTTTTCACCACCAAACCCATCGGCGAAGGCACCGGCCTGGGTCTGTCGATGACCTACGGGTTC
GCACGTCAATCCGGCGGCACCGCGCGCATCACCAGCACCGTGGGCCGTGGCACCACGGTGGCGTTGTTGCTGCCGCGTGG
GCTCTCGGCCAACGAGCTGTTGCCGCCACCGGCGCCCAGCGTGCCACGCACGCGCAACGAGCGCATCTTGCTGGTAGACG
ACACCGACGTGGTGCGCATGATGGTGAGTGAAGTGCTCAGCGATGCCGGCTACCAGGTCATCGAAGCCGAGGATGCCAAC
GGCGCGCTGGAACAATTGCGCACCGAGGTGCATATCGACCTGGTGGTCTCCGATGTCGGCCTGCCCGGCATGAACGGGCG
CGACATGGCCGATGTGGCGCGCATGCTACGCCCGGGTCTGCCGGTCCTGTTCATTACCGGCTACGCCGAAAACGCGGCCA
CGCGGCAAGAATTTCTCGCAGAAGGCATGGCCTTGCTGCCCAAGCCTTTCAGCCTCAACGATCTGCTCAACACGGTGGGG
CAGATGCTCGACAGCAGCGTCCTGGCGCGGGCGTAG

Upstream 100 bases:

>100_bases
GCCGAATTGCTGGGCGGCCGGGTGGGGATCAACAGCGTGGTCGGGCAGGGTTCTGAATTTTACGTGGTGCTGCCGGTGAC
CCTGGCAGCGGAGGAGACAC

Downstream 100 bases:

>100_bases
GGCGTTAAGCGGCTGCTGAAATGCATGCGTAGCTGCGGCGCGGGCGCGGCCGGCGTTGGGACCCTGCATGCACCACGCGT
GCAGCCCCGTTCCTGCACGC

Product: histidine kinase-response regulator hybrid protein

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 651; Mature: 650

Protein sequence:

>651_residues
MGSKHHILVVDDNAVTRYSVRRVLEHHQFVIEEAGTGTEGLAKLATQTFSAVLLDVNLPDMSGFDIVRTLRAEPRTALLP
VVHVSAASIATGDMITGLDAGADAYLIHPVDPNVLLATLRTLLRARRAEEALRISEARFREIFEHISAPIAVVDANLHMH
EANAAFQRLIGSATPGAAIHAAGLDQAAAVHALTTALAQRERWSGTLSLLRDGKLCETEWRVSPYREPDLGLLLVEDVTE
QRLREREQRQELDTATSELAHQIAQRQHTEIQLLQAQKMEALGKLTGGIAHDFNNLLTSIISGLDMIQLAVESNRIERVP
RLAEIATGSAHRAAALTQRMLAFARKQSLDAQPFDVNIRVRSLEDMLQRSIGENIALELELASTPLVAIADANQLENVVL
NLVINARDALKGQGTIRIQSAAYTAHNDPELDDGDYVAVKVIDNGSGIEPAILDQVFEPFFTTKPIGEGTGLGLSMTYGF
ARQSGGTARITSTVGRGTTVALLLPRGLSANELLPPPAPSVPRTRNERILLVDDTDVVRMMVSEVLSDAGYQVIEAEDAN
GALEQLRTEVHIDLVVSDVGLPGMNGRDMADVARMLRPGLPVLFITGYAENAATRQEFLAEGMALLPKPFSLNDLLNTVG
QMLDSSVLARA

Sequences:

>Translated_651_residues
MGSKHHILVVDDNAVTRYSVRRVLEHHQFVIEEAGTGTEGLAKLATQTFSAVLLDVNLPDMSGFDIVRTLRAEPRTALLP
VVHVSAASIATGDMITGLDAGADAYLIHPVDPNVLLATLRTLLRARRAEEALRISEARFREIFEHISAPIAVVDANLHMH
EANAAFQRLIGSATPGAAIHAAGLDQAAAVHALTTALAQRERWSGTLSLLRDGKLCETEWRVSPYREPDLGLLLVEDVTE
QRLREREQRQELDTATSELAHQIAQRQHTEIQLLQAQKMEALGKLTGGIAHDFNNLLTSIISGLDMIQLAVESNRIERVP
RLAEIATGSAHRAAALTQRMLAFARKQSLDAQPFDVNIRVRSLEDMLQRSIGENIALELELASTPLVAIADANQLENVVL
NLVINARDALKGQGTIRIQSAAYTAHNDPELDDGDYVAVKVIDNGSGIEPAILDQVFEPFFTTKPIGEGTGLGLSMTYGF
ARQSGGTARITSTVGRGTTVALLLPRGLSANELLPPPAPSVPRTRNERILLVDDTDVVRMMVSEVLSDAGYQVIEAEDAN
GALEQLRTEVHIDLVVSDVGLPGMNGRDMADVARMLRPGLPVLFITGYAENAATRQEFLAEGMALLPKPFSLNDLLNTVG
QMLDSSVLARA
>Mature_650_residues
GSKHHILVVDDNAVTRYSVRRVLEHHQFVIEEAGTGTEGLAKLATQTFSAVLLDVNLPDMSGFDIVRTLRAEPRTALLPV
VHVSAASIATGDMITGLDAGADAYLIHPVDPNVLLATLRTLLRARRAEEALRISEARFREIFEHISAPIAVVDANLHMHE
ANAAFQRLIGSATPGAAIHAAGLDQAAAVHALTTALAQRERWSGTLSLLRDGKLCETEWRVSPYREPDLGLLLVEDVTEQ
RLREREQRQELDTATSELAHQIAQRQHTEIQLLQAQKMEALGKLTGGIAHDFNNLLTSIISGLDMIQLAVESNRIERVPR
LAEIATGSAHRAAALTQRMLAFARKQSLDAQPFDVNIRVRSLEDMLQRSIGENIALELELASTPLVAIADANQLENVVLN
LVINARDALKGQGTIRIQSAAYTAHNDPELDDGDYVAVKVIDNGSGIEPAILDQVFEPFFTTKPIGEGTGLGLSMTYGFA
RQSGGTARITSTVGRGTTVALLLPRGLSANELLPPPAPSVPRTRNERILLVDDTDVVRMMVSEVLSDAGYQVIEAEDANG
ALEQLRTEVHIDLVVSDVGLPGMNGRDMADVARMLRPGLPVLFITGYAENAATRQEFLAEGMALLPKPFSLNDLLNTVGQ
MLDSSVLARA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=31.9838056680162, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788549, Length=250, Percent_Identity=29.6, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI48994928, Length=383, Percent_Identity=27.6762402088773, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87081816, Length=294, Percent_Identity=29.2517006802721, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788713, Length=262, Percent_Identity=29.0076335877863, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87082012, Length=143, Percent_Identity=32.8671328671329, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788521, Length=150, Percent_Identity=32.6666666666667, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789809, Length=130, Percent_Identity=33.8461538461538, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786784, Length=119, Percent_Identity=34.453781512605, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786911, Length=126, Percent_Identity=37.3015873015873, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790863, Length=118, Percent_Identity=33.0508474576271, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI145693157, Length=127, Percent_Identity=35.4330708661417, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1788191, Length=103, Percent_Identity=35.9223300970874, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70564; Mature: 70433

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSKHHILVVDDNAVTRYSVRRVLEHHQFVIEEAGTGTEGLAKLATQTFSAVLLDVNLPD
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEECCCC
MSGFDIVRTLRAEPRTALLPVVHVSAASIATGDMITGLDAGADAYLIHPVDPNVLLATLR
CCCHHHHHHHHCCCCCEEEHEEEECHHHHCCCCHHCCCCCCCCEEEEECCCCHHHHHHHH
TLLRARRAEEALRISEARFREIFEHISAPIAVVDANLHMHEANAAFQRLIGSATPGAAIH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHCCCCCCCEEE
AAGLDQAAAVHALTTALAQRERWSGTLSLLRDGKLCETEWRVSPYREPDLGLLLVEDVTE
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEEEHHHHHH
QRLREREQRQELDTATSELAHQIAQRQHTEIQLLQAQKMEALGKLTGGIAHDFNNLLTSI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISGLDMIQLAVESNRIERVPRLAEIATGSAHRAAALTQRMLAFARKQSLDAQPFDVNIRV
HCCHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
RSLEDMLQRSIGENIALELELASTPLVAIADANQLENVVLNLVINARDALKGQGTIRIQS
HHHHHHHHHHCCCCEEEEEEECCCCEEEEECHHHHHHHHHHHHCCHHHHHCCCCEEEEEE
AAYTAHNDPELDDGDYVAVKVIDNGSGIEPAILDQVFEPFFTTKPIGEGTGLGLSMTYGF
EEEECCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECH
ARQSGGTARITSTVGRGTTVALLLPRGLSANELLPPPAPSVPRTRNERILLVDDTDVVRM
HHCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHH
MVSEVLSDAGYQVIEAEDANGALEQLRTEVHIDLVVSDVGLPGMNGRDMADVARMLRPGL
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHCCCC
PVLFITGYAENAATRQEFLAEGMALLPKPFSLNDLLNTVGQMLDSSVLARA
CEEEEECCCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GSKHHILVVDDNAVTRYSVRRVLEHHQFVIEEAGTGTEGLAKLATQTFSAVLLDVNLPD
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEECCCC
MSGFDIVRTLRAEPRTALLPVVHVSAASIATGDMITGLDAGADAYLIHPVDPNVLLATLR
CCCHHHHHHHHCCCCCEEEHEEEECHHHHCCCCHHCCCCCCCCEEEEECCCCHHHHHHHH
TLLRARRAEEALRISEARFREIFEHISAPIAVVDANLHMHEANAAFQRLIGSATPGAAIH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHCCCCCCCEEE
AAGLDQAAAVHALTTALAQRERWSGTLSLLRDGKLCETEWRVSPYREPDLGLLLVEDVTE
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEEEHHHHHH
QRLREREQRQELDTATSELAHQIAQRQHTEIQLLQAQKMEALGKLTGGIAHDFNNLLTSI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISGLDMIQLAVESNRIERVPRLAEIATGSAHRAAALTQRMLAFARKQSLDAQPFDVNIRV
HCCHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
RSLEDMLQRSIGENIALELELASTPLVAIADANQLENVVLNLVINARDALKGQGTIRIQS
HHHHHHHHHHCCCCEEEEEEECCCCEEEEECHHHHHHHHHHHHCCHHHHHCCCCEEEEEE
AAYTAHNDPELDDGDYVAVKVIDNGSGIEPAILDQVFEPFFTTKPIGEGTGLGLSMTYGF
EEEECCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECH
ARQSGGTARITSTVGRGTTVALLLPRGLSANELLPPPAPSVPRTRNERILLVDDTDVVRM
HHCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHH
MVSEVLSDAGYQVIEAEDANGALEQLRTEVHIDLVVSDVGLPGMNGRDMADVARMLRPGL
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHCCCC
PVLFITGYAENAATRQEFLAEGMALLPKPFSLNDLLNTVGQMLDSSVLARA
CEEEEECCCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA