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The map label for this gene is 77748557

Identifier: 77748557

GI number: 77748557

Start: 1093770

End: 1095467

Strand: Direct

Name: 77748557

Synonym: XAC0930

Alternate gene names: NA

Gene position: 1093770-1095467 (Clockwise)

Preceding gene: 77748556

Following gene: 21241703

Centisome position: 21.13

GC content: 67.2

Gene sequence:

>1698_bases
ATGCCGTATCACTCAGTAGGCGTACTGCGCCGCGTTGCATTCGTCTGTGCGTTGTCATGCACGTTTCATGCCGCTGCTGG
CGAGGTCAATCTGCAAGGATTGAATTCCAGTAACACCCATCAGCGCTTCATCGTCAGCTACAAGAACAGCGTCGGCAGCA
GCCGGGCGACTGGGTTGTCTGCGCCATGGGGCGACATCGCGCGTGCCGTGCCGCAAGCGCGCGGGAAGGCGCTGGGCCTG
TCGGCCACGCGCCGGCTCAGTGGCGGGCCGATGTTGCTGGTGGCAGACCGCAAGCTGGACCGCGTGGATTCGGAAAGCCT
GATGCGGCGCCTTGCCGCCGACCCGGCGGTCAAACGCGTGGAAGTGGACATCCTGATGCGGCCATTGCTGGTTCCCAACG
ACCCGGGCGTGCCGCAGCAGTGGGCGATGGGCGCGACCGCCGCCAGCCTCAACATCCGTCCGGCCTGGGACCGTTCCACC
GGCAAGGGCATCGTGGTGGCGGTGATCGACACTGGCATCACCAATCATCCGGACCTGGCAGCCAATGTGCTGCCCGGCTA
CGACTTCATCGTTGATCCGGCCACTGCGCGCGATGGCACTGCGCGCGATGCGAACGCCGCCGACCAAGGCGACTGGGCCG
CGGCCAACGAATGCGGGCCCGGAGCGTCGGCGTCCAATTCCAGTTGGCATGGCACGCACGTGGCCGGCATCGTGGCGGCG
GTGGGCAACAACGCGGTGGGCGTGGTCGGTACCGCGTTCAACGCCAAGATCCTGCCGTTGCGGGTGCTGGGCCGCTGCGG
CGGCTACATGTCCGATATCGCCGATGCGATCGTGTGGGCGTCCGGCGGCAAGGTCACTGGCGTGCCGGCCAACCCGAATC
CGGCCACGGTGATCAATCTGTCGTTGGGCGGAGCGGGCACCTGCTCGGCGACGTTGAACAACGCCATCACCGCAGCGGTC
ACGCGCGGCAGCGCGGTGGTCGTGGCCGCCGGCAACAGCAATATGGACGTCTCCACCAGCGTGCCGGCCAATTGCGCCAA
CGTGATCGCCGTGGCCGCCACCACCTCGGCCGGCGCCAAGGCCAGCTTCTCCAACTTCGGCAAGGGCGTGGATATCGCCG
CGCCCGGGCAATCGATCGTGTCCACGCTCAATACCGGAACCACGGCACCGGGCAATCCGGCATATGCGGTGTATAGCGGC
ACCTCGATGGCTGCGCCGCACGTGGCTGGCGTGGTGGCGCTGATGCAGTCGGTGGCCCTGAATCCGCTGACGCCGGCAAC
AGTGAAAGCCCTGCTCAAGGCCAGCGCGCGGCCCATGCCGGTGGCCTGCACGCAGGGGTGCGGGGCCGGGCTGGTGAATG
CCGATGGCGCGGTGGCGGCGGTGATCGAGTCGACCACCTTGAGCAGGAATGTGGCACGCACCGGGCTGAGCGCAGCGCTT
TCCGATTCGCTGTATTACCAGGTCAATGTGCCGGCCGGCACCCGTTCGCTCAAGGTCACGCTCGCCGATGGCAGCGGCAA
CGCCGACCTTTCGGTACGGGCCGGAGCGTTACCGACCGACGCCGCGTACAGCTGCCGCAGCATGTTGCCGGGCAATGGCG
ACAGCTGCACGCTGGCCGCGCCGGCTGCGGGCGTCTATTACGTGCGCTTGAAGGCAACGCTGGGCTTTTCCGGAGTCAGC
GTCACTGCGGCGTATTGA

Upstream 100 bases:

>100_bases
GCATGCAACATCTGCATGCACGCGCATCGGGCACGGCGCAGCGCACTGGCGTCAGCGCGTTGCCAACCGGGTTGCCAGAT
CCTTGGGGAGGGATGGAGTC

Downstream 100 bases:

>100_bases
GTGGTTCCGGCGCGGTGGTGCTGCCGTGTCCAGAGGCGCTGCTGCCTGCTCTAGTGCGGCAGTGCTGCATGCGTGCAATG
CGGAGACATCGGTGGAAGAT

Product: extracellular protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MPYHSVGVLRRVAFVCALSCTFHAAAGEVNLQGLNSSNTHQRFIVSYKNSVGSSRATGLSAPWGDIARAVPQARGKALGL
SATRRLSGGPMLLVADRKLDRVDSESLMRRLAADPAVKRVEVDILMRPLLVPNDPGVPQQWAMGATAASLNIRPAWDRST
GKGIVVAVIDTGITNHPDLAANVLPGYDFIVDPATARDGTARDANAADQGDWAAANECGPGASASNSSWHGTHVAGIVAA
VGNNAVGVVGTAFNAKILPLRVLGRCGGYMSDIADAIVWASGGKVTGVPANPNPATVINLSLGGAGTCSATLNNAITAAV
TRGSAVVVAAGNSNMDVSTSVPANCANVIAVAATTSAGAKASFSNFGKGVDIAAPGQSIVSTLNTGTTAPGNPAYAVYSG
TSMAAPHVAGVVALMQSVALNPLTPATVKALLKASARPMPVACTQGCGAGLVNADGAVAAVIESTTLSRNVARTGLSAAL
SDSLYYQVNVPAGTRSLKVTLADGSGNADLSVRAGALPTDAAYSCRSMLPGNGDSCTLAAPAAGVYYVRLKATLGFSGVS
VTAAY

Sequences:

>Translated_565_residues
MPYHSVGVLRRVAFVCALSCTFHAAAGEVNLQGLNSSNTHQRFIVSYKNSVGSSRATGLSAPWGDIARAVPQARGKALGL
SATRRLSGGPMLLVADRKLDRVDSESLMRRLAADPAVKRVEVDILMRPLLVPNDPGVPQQWAMGATAASLNIRPAWDRST
GKGIVVAVIDTGITNHPDLAANVLPGYDFIVDPATARDGTARDANAADQGDWAAANECGPGASASNSSWHGTHVAGIVAA
VGNNAVGVVGTAFNAKILPLRVLGRCGGYMSDIADAIVWASGGKVTGVPANPNPATVINLSLGGAGTCSATLNNAITAAV
TRGSAVVVAAGNSNMDVSTSVPANCANVIAVAATTSAGAKASFSNFGKGVDIAAPGQSIVSTLNTGTTAPGNPAYAVYSG
TSMAAPHVAGVVALMQSVALNPLTPATVKALLKASARPMPVACTQGCGAGLVNADGAVAAVIESTTLSRNVARTGLSAAL
SDSLYYQVNVPAGTRSLKVTLADGSGNADLSVRAGALPTDAAYSCRSMLPGNGDSCTLAAPAAGVYYVRLKATLGFSGVS
VTAAY
>Mature_564_residues
PYHSVGVLRRVAFVCALSCTFHAAAGEVNLQGLNSSNTHQRFIVSYKNSVGSSRATGLSAPWGDIARAVPQARGKALGLS
ATRRLSGGPMLLVADRKLDRVDSESLMRRLAADPAVKRVEVDILMRPLLVPNDPGVPQQWAMGATAASLNIRPAWDRSTG
KGIVVAVIDTGITNHPDLAANVLPGYDFIVDPATARDGTARDANAADQGDWAAANECGPGASASNSSWHGTHVAGIVAAV
GNNAVGVVGTAFNAKILPLRVLGRCGGYMSDIADAIVWASGGKVTGVPANPNPATVINLSLGGAGTCSATLNNAITAAVT
RGSAVVVAAGNSNMDVSTSVPANCANVIAVAATTSAGAKASFSNFGKGVDIAAPGQSIVSTLNTGTTAPGNPAYAVYSGT
SMAAPHVAGVVALMQSVALNPLTPATVKALLKASARPMPVACTQGCGAGLVNADGAVAAVIESTTLSRNVARTGLSAALS
DSLYYQVNVPAGTRSLKVTLADGSGNADLSVRAGALPTDAAYSCRSMLPGNGDSCTLAAPAAGVYYVRLKATLGFSGVSV
TAAY

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4505579, Length=360, Percent_Identity=28.6111111111111, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI20336180, Length=371, Percent_Identity=28.3018867924528, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4505577, Length=371, Percent_Identity=28.3018867924528, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI20336190, Length=410, Percent_Identity=27.3170731707317, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI27894285, Length=410, Percent_Identity=27.3170731707317, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI20336188, Length=410, Percent_Identity=27.3170731707317, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI76443679, Length=368, Percent_Identity=27.9891304347826, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI20336184, Length=371, Percent_Identity=28.3018867924528, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI20336186, Length=372, Percent_Identity=28.2258064516129, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI20336182, Length=371, Percent_Identity=28.3018867924528, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71983555, Length=400, Percent_Identity=26.25, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25141268, Length=405, Percent_Identity=26.1728395061728, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320775, Length=346, Percent_Identity=29.1907514450867, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324576, Length=350, Percent_Identity=27.7142857142857, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6319893, Length=267, Percent_Identity=30.3370786516854, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281360987, Length=356, Percent_Identity=28.6516853932584, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24642494, Length=356, Percent_Identity=28.6516853932584, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24642490, Length=356, Percent_Identity=28.6516853932584, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI45555723, Length=356, Percent_Identity=28.6516853932584, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24642492, Length=356, Percent_Identity=28.6516853932584, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24642488, Length=359, Percent_Identity=28.133704735376, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24642484, Length=359, Percent_Identity=28.133704735376, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24642486, Length=359, Percent_Identity=28.133704735376, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281360985, Length=164, Percent_Identity=34.7560975609756, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24650056, Length=373, Percent_Identity=23.3243967828418, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI45553515, Length=373, Percent_Identity=23.3243967828418, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650058, Length=373, Percent_Identity=23.3243967828418, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650060, Length=373, Percent_Identity=23.3243967828418, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45553513, Length=373, Percent_Identity=23.3243967828418, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17864552, Length=373, Percent_Identity=23.3243967828418, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 56745; Mature: 56614

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYHSVGVLRRVAFVCALSCTFHAAAGEVNLQGLNSSNTHQRFIVSYKNSVGSSRATGLS
CCCHHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCC
APWGDIARAVPQARGKALGLSATRRLSGGPMLLVADRKLDRVDSESLMRRLAADPAVKRV
CCHHHHHHHHHHHCCCEECCCHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCHHEE
EVDILMRPLLVPNDPGVPQQWAMGATAASLNIRPAWDRSTGKGIVVAVIDTGITNHPDLA
EEEEHCCCEECCCCCCCCHHHHCCCEEEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCH
ANVLPGYDFIVDPATARDGTARDANAADQGDWAAANECGPGASASNSSWHGTHVAGIVAA
HHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
VGNNAVGVVGTAFNAKILPLRVLGRCGGYMSDIADAIVWASGGKVTGVPANPNPATVINL
HCCCCEEEEEECCCCEEEHHHHHHHCCCHHHHHHHHEEECCCCEEEECCCCCCCCEEEEE
SLGGAGTCSATLNNAITAAVTRGSAVVVAAGNSNMDVSTSVPANCANVIAVAATTSAGAK
ECCCCCCCHHHHCCCEEEEEECCCEEEEEECCCCCEEECCCCCCCCCEEEEEEECCCCCC
ASFSNFGKGVDIAAPGQSIVSTLNTGTTAPGNPAYAVYSGTSMAAPHVAGVVALMQSVAL
CCHHHCCCCCEECCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCC
NPLTPATVKALLKASARPMPVACTQGCGAGLVNADGAVAAVIESTTLSRNVARTGLSAAL
CCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
SDSLYYQVNVPAGTRSLKVTLADGSGNADLSVRAGALPTDAAYSCRSMLPGNGDSCTLAA
CCCEEEEEECCCCCEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCEEEEEC
PAAGVYYVRLKATLGFSGVSVTAAY
CCCCEEEEEEEEEECCCCEEEEEEC
>Mature Secondary Structure 
PYHSVGVLRRVAFVCALSCTFHAAAGEVNLQGLNSSNTHQRFIVSYKNSVGSSRATGLS
CCHHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCC
APWGDIARAVPQARGKALGLSATRRLSGGPMLLVADRKLDRVDSESLMRRLAADPAVKRV
CCHHHHHHHHHHHCCCEECCCHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCHHEE
EVDILMRPLLVPNDPGVPQQWAMGATAASLNIRPAWDRSTGKGIVVAVIDTGITNHPDLA
EEEEHCCCEECCCCCCCCHHHHCCCEEEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCH
ANVLPGYDFIVDPATARDGTARDANAADQGDWAAANECGPGASASNSSWHGTHVAGIVAA
HHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
VGNNAVGVVGTAFNAKILPLRVLGRCGGYMSDIADAIVWASGGKVTGVPANPNPATVINL
HCCCCEEEEEECCCCEEEHHHHHHHCCCHHHHHHHHEEECCCCEEEECCCCCCCCEEEEE
SLGGAGTCSATLNNAITAAVTRGSAVVVAAGNSNMDVSTSVPANCANVIAVAATTSAGAK
ECCCCCCCHHHHCCCEEEEEECCCEEEEEECCCCCEEECCCCCCCCCEEEEEEECCCCCC
ASFSNFGKGVDIAAPGQSIVSTLNTGTTAPGNPAYAVYSGTSMAAPHVAGVVALMQSVAL
CCHHHCCCCCEECCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCC
NPLTPATVKALLKASARPMPVACTQGCGAGLVNADGAVAAVIESTTLSRNVARTGLSAAL
CCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
SDSLYYQVNVPAGTRSLKVTLADGSGNADLSVRAGALPTDAAYSCRSMLPGNGDSCTLAA
CCCEEEEEECCCCCEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCEEEEEC
PAAGVYYVRLKATLGFSGVSVTAAY
CCCCEEEEEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]