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The map label for this gene is 77748556

Identifier: 77748556

GI number: 77748556

Start: 1091789

End: 1093429

Strand: Direct

Name: 77748556

Synonym: XAC0929

Alternate gene names: NA

Gene position: 1091789-1093429 (Clockwise)

Preceding gene: 21241698

Following gene: 77748557

Centisome position: 21.1

GC content: 68.37

Gene sequence:

>1641_bases
ATGACGTCAGGGAACGCTGCCACCATCGCTTCAACCCCATTTGCGATACCTCGCCCAGGTCTGCCGTTTCGGCAGGCGCA
GGCGATGTGTTGCCACTTGGCCGGAATGGACGCCGGTCAGTCGCTCCGACGGGCCTGGCGCCCGTGCAGTTTCCGGCCCC
GAACCGCAGCCTGCGGCAAAGGGCAGGCCCTCTCGCCGCAGCTGCGGCACCTCTCCAATAAGGAACGATCGATGTCCAAT
GTGTCGCAACGTCGTGCGCCCACGCGCGCGCTGGTAGTCCTGGGTGTTTCCGCGTTGACCTCGCTGCTGGCCGTGCCGGC
ATTCGCCGGTCAGGTCAATCTGTCCGGGTTGGATGCGCAGCCCACCCTGGACCGCTTCATCGTCAAATACAAGGACGGTT
CCAGTGCGGCGGTCAGCCCCACCTCGATGCGCGCATCGCTCAATTCCGTCGCCGGTGCGATGCCGGCACGCGCCGGCCGT
GCGCTGGGCCTGAACCACGTGCGCCGCACGGCGCTGGGTTCGGAAGTGCTCAAGACCGACCGTGGCCTGGACCGCGCCGA
CGCCGAAACGCTGATGCGCCGCATTGCTGCCGACCCCAGCGTGGACTATGTGGAAGTCGACCAGATCATGTACCCGGTGC
TGACCCCGAACGACACGCGCCTGTCCGAACAGTGGGGCTTCGGCACCTCTTCCTCCAGCATCAACGTGCGCCCGGCCTGG
GACACCGCCACCGGCACCGGCGTGGTGGTGGCGGTGATCGACACCGGCATCACCAGCCATCCTGACCTCAACGCCAACGT
GCTGCCGGGTTACGACTTCATCAGCGATGCCACGCGTGCACGCGACAACAACGGGCGTGACAGCAATCCGGCCGACCAGG
GCGACTGGACCACGGCCGGCCAGTGCGGCAGCGGCACCTCGGCCGCCAATTCCAGCTGGCACGGCACGCATGTGGCCGGC
ACCATCGCGGCGGTGACCAACAACAGCACCGGCGTGGCCGGTACCGCGTTCAACGCGCGCATCGTGCCGATCCGTGCGCT
GGGCGCATGCGGCGGCGCCACGTCCGATATCGTCGATGCGATCGTGTGGGCCTCCGGCGGCACCGTGTCCGGCGTGCCGG
CCAATGCCAACCCGGCCGAAGTGATCAACATGTCGCTGGGCGGCAGCGGCAGCTGCTCGAGCAGTTACCAGAATGCGATC
AACAGCGCGGTGTCGCGCGGCACCACCGTGGTGGTGGCGGCCGGCAACAGCAATGCCAACGTGGCCAACTTCACCCCGGC
CAGCTGCGCCAACGTGATTTCGGTGGCGTCGATCACCTCGGCCGGGGCGCGTTCGAGCTTCTCCAACTACGGCACCGGCA
TCGACATCTCCGCGCCGGGTTCGGCGATCCTGTCGACCTTGAACAGCGGCACCACCACGCCGGGTTCGGCCAGCTACGCC
AGCTACAACGGCACCTCGATGGCGGCCCCGCACGTGGCCGGCGTGGTGGCGCTGGTGCAGTCGGTCGCCAGCCGTCCGCT
GACGCCTGCGGCGGTGGAAACGCTGCTGAAGAACACTGCACGTCCGCTGCCGGGCGCCTGCTCGGGCGGCTGCGGCGCGG
GCATCGTCAACGCGGCCGGCGCGGTCAGCCAGACCCCGTAA

Upstream 100 bases:

>100_bases
CGGGAACCTATTACGTGCGGATCAAGGCTTACAGCACGTTCTCCGGCGTGACCCTGACCGCCAGCTACTAAACGCTGGAT
CGCTGCACGCGTTCCCTGGC

Downstream 100 bases:

>100_bases
ACCTGCGCCGACGACCGCGATGCCGGCACGCAGCCGGCATCGCGTCGGGCCTTTCCCGACGCCCGTGTCGGTGGTTTGAA
ACCTGCACTGCCCCGCTCTA

Product: extracellular protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MTSGNAATIASTPFAIPRPGLPFRQAQAMCCHLAGMDAGQSLRRAWRPCSFRPRTAACGKGQALSPQLRHLSNKERSMSN
VSQRRAPTRALVVLGVSALTSLLAVPAFAGQVNLSGLDAQPTLDRFIVKYKDGSSAAVSPTSMRASLNSVAGAMPARAGR
ALGLNHVRRTALGSEVLKTDRGLDRADAETLMRRIAADPSVDYVEVDQIMYPVLTPNDTRLSEQWGFGTSSSSINVRPAW
DTATGTGVVVAVIDTGITSHPDLNANVLPGYDFISDATRARDNNGRDSNPADQGDWTTAGQCGSGTSAANSSWHGTHVAG
TIAAVTNNSTGVAGTAFNARIVPIRALGACGGATSDIVDAIVWASGGTVSGVPANANPAEVINMSLGGSGSCSSSYQNAI
NSAVSRGTTVVVAAGNSNANVANFTPASCANVISVASITSAGARSSFSNYGTGIDISAPGSAILSTLNSGTTTPGSASYA
SYNGTSMAAPHVAGVVALVQSVASRPLTPAAVETLLKNTARPLPGACSGGCGAGIVNAAGAVSQTP

Sequences:

>Translated_546_residues
MTSGNAATIASTPFAIPRPGLPFRQAQAMCCHLAGMDAGQSLRRAWRPCSFRPRTAACGKGQALSPQLRHLSNKERSMSN
VSQRRAPTRALVVLGVSALTSLLAVPAFAGQVNLSGLDAQPTLDRFIVKYKDGSSAAVSPTSMRASLNSVAGAMPARAGR
ALGLNHVRRTALGSEVLKTDRGLDRADAETLMRRIAADPSVDYVEVDQIMYPVLTPNDTRLSEQWGFGTSSSSINVRPAW
DTATGTGVVVAVIDTGITSHPDLNANVLPGYDFISDATRARDNNGRDSNPADQGDWTTAGQCGSGTSAANSSWHGTHVAG
TIAAVTNNSTGVAGTAFNARIVPIRALGACGGATSDIVDAIVWASGGTVSGVPANANPAEVINMSLGGSGSCSSSYQNAI
NSAVSRGTTVVVAAGNSNANVANFTPASCANVISVASITSAGARSSFSNYGTGIDISAPGSAILSTLNSGTTTPGSASYA
SYNGTSMAAPHVAGVVALVQSVASRPLTPAAVETLLKNTARPLPGACSGGCGAGIVNAAGAVSQTP
>Mature_545_residues
TSGNAATIASTPFAIPRPGLPFRQAQAMCCHLAGMDAGQSLRRAWRPCSFRPRTAACGKGQALSPQLRHLSNKERSMSNV
SQRRAPTRALVVLGVSALTSLLAVPAFAGQVNLSGLDAQPTLDRFIVKYKDGSSAAVSPTSMRASLNSVAGAMPARAGRA
LGLNHVRRTALGSEVLKTDRGLDRADAETLMRRIAADPSVDYVEVDQIMYPVLTPNDTRLSEQWGFGTSSSSINVRPAWD
TATGTGVVVAVIDTGITSHPDLNANVLPGYDFISDATRARDNNGRDSNPADQGDWTTAGQCGSGTSAANSSWHGTHVAGT
IAAVTNNSTGVAGTAFNARIVPIRALGACGGATSDIVDAIVWASGGTVSGVPANANPAEVINMSLGGSGSCSSSYQNAIN
SAVSRGTTVVVAAGNSNANVANFTPASCANVISVASITSAGARSSFSNYGTGIDISAPGSAILSTLNSGTTTPGSASYAS
YNGTSMAAPHVAGVVALVQSVASRPLTPAAVETLLKNTARPLPGACSGGCGAGIVNAAGAVSQTP

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4505579, Length=358, Percent_Identity=27.6536312849162, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI20336180, Length=382, Percent_Identity=28.2722513089005, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4505577, Length=382, Percent_Identity=28.2722513089005, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI20336182, Length=374, Percent_Identity=27.2727272727273, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI20336184, Length=374, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI20336188, Length=374, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI20336190, Length=374, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI20336186, Length=374, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI27894285, Length=374, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI299523015, Length=324, Percent_Identity=27.7777777777778, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI76443679, Length=369, Percent_Identity=26.2872628726287, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI20336246, Length=324, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71983555, Length=337, Percent_Identity=27.893175074184, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25141268, Length=337, Percent_Identity=27.893175074184, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71988321, Length=350, Percent_Identity=27.1428571428571, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71988308, Length=350, Percent_Identity=27.1428571428571, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71988315, Length=350, Percent_Identity=27.1428571428571, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71988297, Length=350, Percent_Identity=27.1428571428571, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71988301, Length=359, Percent_Identity=26.7409470752089, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71988312, Length=350, Percent_Identity=27.1428571428571, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320775, Length=325, Percent_Identity=32, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6324576, Length=344, Percent_Identity=28.1976744186047, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319893, Length=278, Percent_Identity=29.8561151079137, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281360987, Length=361, Percent_Identity=28.5318559556787, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24642494, Length=361, Percent_Identity=28.5318559556787, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642490, Length=361, Percent_Identity=28.5318559556787, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45555723, Length=361, Percent_Identity=28.5318559556787, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642492, Length=361, Percent_Identity=28.5318559556787, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642488, Length=364, Percent_Identity=28.2967032967033, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24642484, Length=364, Percent_Identity=28.2967032967033, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24642486, Length=364, Percent_Identity=28.2967032967033, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24650056, Length=335, Percent_Identity=26.2686567164179, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24650058, Length=335, Percent_Identity=25.9701492537313, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650060, Length=335, Percent_Identity=25.9701492537313, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553513, Length=335, Percent_Identity=25.9701492537313, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553515, Length=335, Percent_Identity=25.9701492537313, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17864552, Length=357, Percent_Identity=25.7703081232493, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281360985, Length=168, Percent_Identity=35.1190476190476, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 55202; Mature: 55071

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGNAATIASTPFAIPRPGLPFRQAQAMCCHLAGMDAGQSLRRAWRPCSFRPRTAACGK
CCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCC
GQALSPQLRHLSNKERSMSNVSQRRAPTRALVVLGVSALTSLLAVPAFAGQVNLSGLDAQ
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCC
PTLDRFIVKYKDGSSAAVSPTSMRASLNSVAGAMPARAGRALGLNHVRRTALGSEVLKTD
CCHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHH
RGLDRADAETLMRRIAADPSVDYVEVDQIMYPVLTPNDTRLSEQWGFGTSSSSINVRPAW
CCCCHHHHHHHHHHHHCCCCCCEEEHHHHEECCCCCCCCCCHHHCCCCCCCCCEEEEECC
DTATGTGVVVAVIDTGITSHPDLNANVLPGYDFISDATRARDNNGRDSNPADQGDWTTAG
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
QCGSGTSAANSSWHGTHVAGTIAAVTNNSTGVAGTAFNARIVPIRALGACGGATSDIVDA
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEECCCEEEEEEEEECCCCCCHHHHHHH
IVWASGGTVSGVPANANPAEVINMSLGGSGSCSSSYQNAINSAVSRGTTVVVAAGNSNAN
HHHCCCCEECCCCCCCCHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCC
VANFTPASCANVISVASITSAGARSSFSNYGTGIDISAPGSAILSTLNSGTTTPGSASYA
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEECCCHHHHHHHHHCCCCCCCCCCCC
SYNGTSMAAPHVAGVVALVQSVASRPLTPAAVETLLKNTARPLPGACSGGCGAGIVNAAG
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCC
AVSQTP
CCCCCC
>Mature Secondary Structure 
TSGNAATIASTPFAIPRPGLPFRQAQAMCCHLAGMDAGQSLRRAWRPCSFRPRTAACGK
CCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCC
GQALSPQLRHLSNKERSMSNVSQRRAPTRALVVLGVSALTSLLAVPAFAGQVNLSGLDAQ
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCC
PTLDRFIVKYKDGSSAAVSPTSMRASLNSVAGAMPARAGRALGLNHVRRTALGSEVLKTD
CCHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHH
RGLDRADAETLMRRIAADPSVDYVEVDQIMYPVLTPNDTRLSEQWGFGTSSSSINVRPAW
CCCCHHHHHHHHHHHHCCCCCCEEEHHHHEECCCCCCCCCCHHHCCCCCCCCCEEEEECC
DTATGTGVVVAVIDTGITSHPDLNANVLPGYDFISDATRARDNNGRDSNPADQGDWTTAG
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
QCGSGTSAANSSWHGTHVAGTIAAVTNNSTGVAGTAFNARIVPIRALGACGGATSDIVDA
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEECCCEEEEEEEEECCCCCCHHHHHHH
IVWASGGTVSGVPANANPAEVINMSLGGSGSCSSSYQNAINSAVSRGTTVVVAAGNSNAN
HHHCCCCEECCCCCCCCHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCC
VANFTPASCANVISVASITSAGARSSFSNYGTGIDISAPGSAILSTLNSGTTTPGSASYA
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEECCCHHHHHHHHHCCCCCCCCCCCC
SYNGTSMAAPHVAGVVALVQSVASRPLTPAAVETLLKNTARPLPGACSGGCGAGIVNAAG
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCC
AVSQTP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]