Click here to switch to the map view.

The map label for this gene is rimK [H]

Identifier: 21243979

GI number: 21243979

Start: 3833099

End: 3833845

Strand: Reverse

Name: rimK [H]

Synonym: XAC3253

Alternate gene names: 21243979

Gene position: 3833845-3833099 (Counterclockwise)

Preceding gene: 21243981

Following gene: 21243978

Centisome position: 74.08

GC content: 66.8

Gene sequence:

>747_bases
ATGAAAATCGCCATCCTTTCCCGCAACAGCAAGCTGTATTCGACCCGGCGGCTGATCGAAGCCGGTCGCAAGCGTGGTCA
CACCGTACGCATCCTCGACCCGTTGCGCTGCTACATGCGCATCGCCGCCGACGGCTTCAGCCTGCACTACAAGGGCAAAC
CGATCACCGGCTTCGATGCGGTGATCCCGCGCATCGGCGCCTCGGTCACTCGCTATGGCACCGCAGTGCTGCGCCAGCTC
GAGTTCATGGGCACCTACACGCCCAACCCGTCGGACGCCATCCTGCGCTCGCGCGACAAACTGCGCGCGCATCAGTTGTT
GGCCGCGCAGGGCATCGACATGCCGGTCACCGTGTTCGGCGACAACCCCGACGACACCCAGGACCTGCTCTCCATGCTCG
GCCCGCCGCCGCATGTGGTGAAGTTGAACGAGGGTGCGCAAGGCGCCGGGGTGATCCTGACCGAAAAGGCCAGCGCCTCG
CGCGGCGTGGTCGAAGCGCTGCGCGGGCTATACGCCAACTTCATCGTGCAGGAGTTCATCGGTGAGGCCGAAGGCGCCGA
CCTGCGCTGCTTCGTGGTCGGCGACAAGGTCGTCGCGGCGATGCGCCGCCAGGCGGCCGAAGGCGATTTTCGGTCCAATC
TGCACCTGGGCGGCACTGCCGCCGTGGCCGAGGCAACCGAACAGGAGCAGGAGGTGGCGGTGCGCTCGGCACGCGCCTTG
GCCTGGCAGTGGCTGGGGTCGACCTGA

Upstream 100 bases:

>100_bases
GGGCCTGCCGCGAACGCGCAATCGGCCTGCACTGTACGGACTTGGGTCACTTCGTCATCAGACTCTGCCCATGTCCAAGC
CGCGCCGCGTACCTGCCGCG

Downstream 100 bases:

>100_bases
TCCGCTCAAGACGCGGCCCGCTGGTGCTGGAGGTCAACTCGACCCCAGGTCTGGAAGGGGTGGAAGGCGTGTGCGGCGTG
GATGTGGCCGCGGCGATTGT

Product: ribosomal protein S6 modification protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKIAILSRNSKLYSTRRLIEAGRKRGHTVRILDPLRCYMRIAADGFSLHYKGKPITGFDAVIPRIGASVTRYGTAVLRQL
EFMGTYTPNPSDAILRSRDKLRAHQLLAAQGIDMPVTVFGDNPDDTQDLLSMLGPPPHVVKLNEGAQGAGVILTEKASAS
RGVVEALRGLYANFIVQEFIGEAEGADLRCFVVGDKVVAAMRRQAAEGDFRSNLHLGGTAAVAEATEQEQEVAVRSARAL
AWQWLGST

Sequences:

>Translated_248_residues
MKIAILSRNSKLYSTRRLIEAGRKRGHTVRILDPLRCYMRIAADGFSLHYKGKPITGFDAVIPRIGASVTRYGTAVLRQL
EFMGTYTPNPSDAILRSRDKLRAHQLLAAQGIDMPVTVFGDNPDDTQDLLSMLGPPPHVVKLNEGAQGAGVILTEKASAS
RGVVEALRGLYANFIVQEFIGEAEGADLRCFVVGDKVVAAMRRQAAEGDFRSNLHLGGTAAVAEATEQEQEVAVRSARAL
AWQWLGST
>Mature_248_residues
MKIAILSRNSKLYSTRRLIEAGRKRGHTVRILDPLRCYMRIAADGFSLHYKGKPITGFDAVIPRIGASVTRYGTAVLRQL
EFMGTYTPNPSDAILRSRDKLRAHQLLAAQGIDMPVTVFGDNPDDTQDLLSMLGPPPHVVKLNEGAQGAGVILTEKASAS
RGVVEALRGLYANFIVQEFIGEAEGADLRCFVVGDKVVAAMRRQAAEGDFRSNLHLGGTAAVAEATEQEQEVAVRSARAL
AWQWLGST

Specific function: Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 [H]

COG id: COG0189

COG function: function code HJ; Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI164663810, Length=211, Percent_Identity=27.9620853080569, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787076, Length=246, Percent_Identity=58.9430894308943, Blast_Score=293, Evalue=5e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013651
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR004666 [H]

Pfam domain/function: PF08443 RimK [H]

EC number: NA

Molecular weight: Translated: 26960; Mature: 26960

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAILSRNSKLYSTRRLIEAGRKRGHTVRILDPLRCYMRIAADGFSLHYKGKPITGFDA
CEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCEEEEECCCCCCCHHH
VIPRIGASVTRYGTAVLRQLEFMGTYTPNPSDAILRSRDKLRAHQLLAAQGIDMPVTVFG
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
DNPDDTQDLLSMLGPPPHVVKLNEGAQGAGVILTEKASASRGVVEALRGLYANFIVQEFI
CCCCCHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
GEAEGADLRCFVVGDKVVAAMRRQAAEGDFRSNLHLGGTAAVAEATEQEQEVAVRSARAL
CCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AWQWLGST
HHHHCCCC
>Mature Secondary Structure
MKIAILSRNSKLYSTRRLIEAGRKRGHTVRILDPLRCYMRIAADGFSLHYKGKPITGFDA
CEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCEEEEECCCCCCCHHH
VIPRIGASVTRYGTAVLRQLEFMGTYTPNPSDAILRSRDKLRAHQLLAAQGIDMPVTVFG
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
DNPDDTQDLLSMLGPPPHVVKLNEGAQGAGVILTEKASASRGVVEALRGLYANFIVQEFI
CCCCCHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
GEAEGADLRCFVVGDKVVAAMRRQAAEGDFRSNLHLGGTAAVAEATEQEQEVAVRSARAL
CCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AWQWLGST
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Glu; Ribosomal protein S6 [C]

Specific reaction: Catalyzes the addition of glutamic acids to the carboxyl end of ribosomal protein S6 [C]

General reaction: Ligases; Forming Carbon-Nitrogen Bonds; Acid-D-Amino-Acid Ligases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]