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The map label for this gene is yheS [H]

Identifier: 21243891

GI number: 21243891

Start: 3717256

End: 3719175

Strand: Reverse

Name: yheS [H]

Synonym: XAC3165

Alternate gene names: 21243891

Gene position: 3719175-3717256 (Counterclockwise)

Preceding gene: 21243896

Following gene: 21243890

Centisome position: 71.86

GC content: 65.94

Gene sequence:

>1920_bases
ATGATTTCCCTGCGTAACTTCTCCATGCGACGCGGCGAGCGTCTGCTGCTCTCCAACGTCGACCTGACCATGCACGCCGG
CTACCGCGTCGGTGTGGTCGGCCGTAACGGCACCGGCAAGTCGAGCCTGTTCGCTGCGGTGAAGGGCGAGCTGGAGGCCG
ACAAGGGCGATGTCGATCTGCCCGGCAAGGTGCGCACGGCCAGCGTTTCGCAGGAAACCCCGTCCTTGCCCGACCCGGCG
CTGTCGTTCGTACTGGGTGGGGACATCGAGGTCTCCGCGGTGCTGCAGGAAGAAGCCGCAGCCACTGCGCGCGAAGACTG
GGAGGCGGTGGCCAACGCACACCAGAAGATGGCCGAGATCGGCGCCTACGACGCCGAAGCGCGCGCCGGCAAGTTGCTGC
ACGGTCTGGGATTTCCGGCAGACACGCACCATCGCGCGGTGTCGTCGTTCTCCGGCGGCTGGCGCGTGCGGCTGAATCTG
GCGCGCGCGCTGATGATGCCCAGCGACCTGCTGCTGCTCGACGAACCAACCAACCACTTGGACATGGATGCGGTGCTGTG
GCTGGAGCAGTGGCTGCTCAAGTACCCGGGCACGCTGCTGCTGATTTCGCATGACCGCGAATTTCTCGACAACGTGGCCA
CCCACACCCTGCACCTGCATGGTGGCACCGCCAAGCTGTATGTCGGTGGCTACACCGATTTCGAACGCCAGCGCATCGAA
CATTTGCGGCAGCAGCAGATCGCGCATGACAAGGAACAGGCCGAGCGCGCGCATCTGCAGAGCTTCATCGACCGCTTCAA
GGCGCAGGCCAGCAAGGCGACCCAGGCGCAGAGCCGCATGAAGCGCCTGGCCAAGATGGCCGGCACCGAGGCGGTGCGCG
CCGAGCGCGAGTTTCGCATCCAGTTCGCGCAGCCCAATCGGCTGCCGTTTTCGCTGATCCGGCTCAATCACGTGGAAGCC
GGCTATCCCGCGCCCGCAACCCTTCCCCCGCGTGCGGGGGAAGGTGCCCGAAGGGCGGATGGGGGTGACGCCGCCACGGT
CATCCTGCACGATGTCGGTTTCGGCCTGGAAGCGGGTGATCGGATCGGGTTGTTGGGGCCCAATGGCGCGGGTAAGTCCA
CCCTGGTCAAGACCTTGGTGGGCGAACTGGCACCGCTGGCAGGCGAGCGCAGCGCACATCCGGATTTGCGCATCGGTTAC
TTCGCCCAGCACACGGTGGAATCGCTGCACGAAGGCCAGTCGCCGATGGACCACTTCCGCGAGCTGTCGCCGGATGGCGC
CAATCAGGCGTTCCGCGACTTTTTGGGTAAATGGAATTTTGCCGGCGACCGCGCCTTCGAAGTGGTGGATGGCTTCTCCG
GCGGCGAGCGCGCGCGTCTGGCGCTGGCGTTGATCGCCTGGCAGCAGCCGAACGTGCTGTTGCTCGACGAACCGACCAAC
CACTTGGACCTGGAAATGCGTGAAGCGCTGGCCGAGGCGCTGAGCGATTTCGAGGGGGCCATCGTGATGGTCTCCCACGA
TCGCCATCTGATCGGCCTGGTCTGCGACAGTTTCTGGCGCGTGGCCGATGGCGTGGTCGAGCCGTTCGCCGGCGACCTGG
ACGAATATGCGGCCTGGTTGCGTAGTCGCCCGGCTGCGCAGGGCACCAAGCAGAAGATGGCCGAAGTGGCGCCGACCCCG
CCACCGCCGACCAAGCCGCTGCCGCCGAAAAAGGCCGTCAACCCGCACAAGCTGGCCAGCGCCGAAAAGCGCGTCGGCGA
GCTGGAAGCGGCGCTTGCTGCGCTGGATCGCGAGCTGGCCAATCCCGGCAACTACGCCGACAGCGAGAAGATGGCCGTGC
TCGGACGCGACCGCGAAGCAACCGCGCAGCAGCTGGCTGAAGCCGAGACGGCGTGGATGGAATTGATCGACGGTGCGTAA

Upstream 100 bases:

>100_bases
GGCCACGCTGAAGGCGCTAATTATTCGTTAACGCTAGAATGGCGTCGCAGGAATGCTGCTCATCTGCTCATTCCTTTTCG
TTCTATCGGACTGTCCATCA

Downstream 100 bases:

>100_bases
GAGCGGCTGACAACACGACTGCGCAGCCAACGGGTGGCTGCGGCCGGTGCTCGGTGCGGCAGGTAACACGCTTACGTTGC
GGTTCTGCGCACGGTTCGTA

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MISLRNFSMRRGERLLLSNVDLTMHAGYRVGVVGRNGTGKSSLFAAVKGELEADKGDVDLPGKVRTASVSQETPSLPDPA
LSFVLGGDIEVSAVLQEEAAATAREDWEAVANAHQKMAEIGAYDAEARAGKLLHGLGFPADTHHRAVSSFSGGWRVRLNL
ARALMMPSDLLLLDEPTNHLDMDAVLWLEQWLLKYPGTLLLISHDREFLDNVATHTLHLHGGTAKLYVGGYTDFERQRIE
HLRQQQIAHDKEQAERAHLQSFIDRFKAQASKATQAQSRMKRLAKMAGTEAVRAEREFRIQFAQPNRLPFSLIRLNHVEA
GYPAPATLPPRAGEGARRADGGDAATVILHDVGFGLEAGDRIGLLGPNGAGKSTLVKTLVGELAPLAGERSAHPDLRIGY
FAQHTVESLHEGQSPMDHFRELSPDGANQAFRDFLGKWNFAGDRAFEVVDGFSGGERARLALALIAWQQPNVLLLDEPTN
HLDLEMREALAEALSDFEGAIVMVSHDRHLIGLVCDSFWRVADGVVEPFAGDLDEYAAWLRSRPAAQGTKQKMAEVAPTP
PPPTKPLPPKKAVNPHKLASAEKRVGELEAALAALDRELANPGNYADSEKMAVLGRDREATAQQLAEAETAWMELIDGA

Sequences:

>Translated_639_residues
MISLRNFSMRRGERLLLSNVDLTMHAGYRVGVVGRNGTGKSSLFAAVKGELEADKGDVDLPGKVRTASVSQETPSLPDPA
LSFVLGGDIEVSAVLQEEAAATAREDWEAVANAHQKMAEIGAYDAEARAGKLLHGLGFPADTHHRAVSSFSGGWRVRLNL
ARALMMPSDLLLLDEPTNHLDMDAVLWLEQWLLKYPGTLLLISHDREFLDNVATHTLHLHGGTAKLYVGGYTDFERQRIE
HLRQQQIAHDKEQAERAHLQSFIDRFKAQASKATQAQSRMKRLAKMAGTEAVRAEREFRIQFAQPNRLPFSLIRLNHVEA
GYPAPATLPPRAGEGARRADGGDAATVILHDVGFGLEAGDRIGLLGPNGAGKSTLVKTLVGELAPLAGERSAHPDLRIGY
FAQHTVESLHEGQSPMDHFRELSPDGANQAFRDFLGKWNFAGDRAFEVVDGFSGGERARLALALIAWQQPNVLLLDEPTN
HLDLEMREALAEALSDFEGAIVMVSHDRHLIGLVCDSFWRVADGVVEPFAGDLDEYAAWLRSRPAAQGTKQKMAEVAPTP
PPPTKPLPPKKAVNPHKLASAEKRVGELEAALAALDRELANPGNYADSEKMAVLGRDREATAQQLAEAETAWMELIDGA
>Mature_639_residues
MISLRNFSMRRGERLLLSNVDLTMHAGYRVGVVGRNGTGKSSLFAAVKGELEADKGDVDLPGKVRTASVSQETPSLPDPA
LSFVLGGDIEVSAVLQEEAAATAREDWEAVANAHQKMAEIGAYDAEARAGKLLHGLGFPADTHHRAVSSFSGGWRVRLNL
ARALMMPSDLLLLDEPTNHLDMDAVLWLEQWLLKYPGTLLLISHDREFLDNVATHTLHLHGGTAKLYVGGYTDFERQRIE
HLRQQQIAHDKEQAERAHLQSFIDRFKAQASKATQAQSRMKRLAKMAGTEAVRAEREFRIQFAQPNRLPFSLIRLNHVEA
GYPAPATLPPRAGEGARRADGGDAATVILHDVGFGLEAGDRIGLLGPNGAGKSTLVKTLVGELAPLAGERSAHPDLRIGY
FAQHTVESLHEGQSPMDHFRELSPDGANQAFRDFLGKWNFAGDRAFEVVDGFSGGERARLALALIAWQQPNVLLLDEPTN
HLDLEMREALAEALSDFEGAIVMVSHDRHLIGLVCDSFWRVADGVVEPFAGDLDEYAAWLRSRPAAQGTKQKMAEVAPTP
PPPTKPLPPKKAVNPHKLASAEKRVGELEAALAALDRELANPGNYADSEKMAVLGRDREATAQQLAEAETAWMELIDGA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=556, Percent_Identity=37.2302158273381, Blast_Score=353, Evalue=3e-97,
Organism=Homo sapiens, GI10947137, Length=549, Percent_Identity=35.3369763205829, Blast_Score=328, Evalue=9e-90,
Organism=Homo sapiens, GI27881506, Length=549, Percent_Identity=35.3369763205829, Blast_Score=327, Evalue=2e-89,
Organism=Homo sapiens, GI10947135, Length=557, Percent_Identity=33.0341113105925, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI69354671, Length=557, Percent_Identity=33.0341113105925, Blast_Score=250, Evalue=3e-66,
Organism=Escherichia coli, GI1789751, Length=654, Percent_Identity=44.954128440367, Blast_Score=533, Evalue=1e-152,
Organism=Escherichia coli, GI1787041, Length=552, Percent_Identity=34.2391304347826, Blast_Score=303, Evalue=3e-83,
Organism=Escherichia coli, GI1787182, Length=526, Percent_Identity=28.8973384030418, Blast_Score=200, Evalue=3e-52,
Organism=Escherichia coli, GI2367384, Length=567, Percent_Identity=29.1005291005291, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI87081782, Length=543, Percent_Identity=26.8876611418048, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788165, Length=170, Percent_Identity=34.1176470588235, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787029, Length=241, Percent_Identity=28.6307053941909, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788506, Length=262, Percent_Identity=24.4274809160305, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081834, Length=199, Percent_Identity=28.1407035175879, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=547, Percent_Identity=37.6599634369287, Blast_Score=348, Evalue=6e-96,
Organism=Caenorhabditis elegans, GI17555318, Length=538, Percent_Identity=34.5724907063197, Blast_Score=317, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17559834, Length=563, Percent_Identity=33.214920071048, Blast_Score=294, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6321121, Length=579, Percent_Identity=34.0241796200345, Blast_Score=339, Evalue=8e-94,
Organism=Saccharomyces cerevisiae, GI6320874, Length=547, Percent_Identity=29.981718464351, Blast_Score=267, Evalue=5e-72,
Organism=Saccharomyces cerevisiae, GI6325030, Length=413, Percent_Identity=30.9927360774818, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6323278, Length=426, Percent_Identity=28.6384976525822, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6324314, Length=428, Percent_Identity=26.8691588785047, Blast_Score=143, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24666836, Length=543, Percent_Identity=37.3848987108656, Blast_Score=368, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24642252, Length=561, Percent_Identity=35.8288770053476, Blast_Score=344, Evalue=1e-94,
Organism=Drosophila melanogaster, GI18859989, Length=561, Percent_Identity=35.8288770053476, Blast_Score=344, Evalue=1e-94,
Organism=Drosophila melanogaster, GI24641342, Length=552, Percent_Identity=31.7028985507246, Blast_Score=288, Evalue=8e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 69697; Mature: 69697

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLRNFSMRRGERLLLSNVDLTMHAGYRVGVVGRNGTGKSSLFAAVKGELEADKGDVDL
CCCCCCCHHHCCCEEEEECCCEEEECCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
PGKVRTASVSQETPSLPDPALSFVLGGDIEVSAVLQEEAAATAREDWEAVANAHQKMAEI
CCCEEECCCCCCCCCCCCHHHHHEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAYDAEARAGKLLHGLGFPADTHHRAVSSFSGGWRVRLNLARALMMPSDLLLLDEPTNHL
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEHHHHHHCCCCEEEEECCCCCC
DMDAVLWLEQWLLKYPGTLLLISHDREFLDNVATHTLHLHGGTAKLYVGGYTDFERQRIE
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHEEEEEECCEEEEEECCCCHHHHHHHH
HLRQQQIAHDKEQAERAHLQSFIDRFKAQASKATQAQSRMKRLAKMAGTEAVRAEREFRI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCEEEE
QFAQPNRLPFSLIRLNHVEAGYPAPATLPPRAGEGARRADGGDAATVILHDVGFGLEAGD
EECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCC
RIGLLGPNGAGKSTLVKTLVGELAPLAGERSAHPDLRIGYFAQHTVESLHEGQSPMDHFR
EEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCHHHHHH
ELSPDGANQAFRDFLGKWNFAGDRAFEVVDGFSGGERARLALALIAWQQPNVLLLDEPTN
HCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHEEEEEEEECCCCEEEEECCCC
HLDLEMREALAEALSDFEGAIVMVSHDRHLIGLVCDSFWRVADGVVEPFAGDLDEYAAWL
CCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RSRPAAQGTKQKMAEVAPTPPPPTKPLPPKKAVNPHKLASAEKRVGELEAALAALDRELA
HCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
NPGNYADSEKMAVLGRDREATAQQLAEAETAWMELIDGA
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISLRNFSMRRGERLLLSNVDLTMHAGYRVGVVGRNGTGKSSLFAAVKGELEADKGDVDL
CCCCCCCHHHCCCEEEEECCCEEEECCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
PGKVRTASVSQETPSLPDPALSFVLGGDIEVSAVLQEEAAATAREDWEAVANAHQKMAEI
CCCEEECCCCCCCCCCCCHHHHHEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAYDAEARAGKLLHGLGFPADTHHRAVSSFSGGWRVRLNLARALMMPSDLLLLDEPTNHL
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEHHHHHHCCCCEEEEECCCCCC
DMDAVLWLEQWLLKYPGTLLLISHDREFLDNVATHTLHLHGGTAKLYVGGYTDFERQRIE
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHEEEEEECCEEEEEECCCCHHHHHHHH
HLRQQQIAHDKEQAERAHLQSFIDRFKAQASKATQAQSRMKRLAKMAGTEAVRAEREFRI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCEEEE
QFAQPNRLPFSLIRLNHVEAGYPAPATLPPRAGEGARRADGGDAATVILHDVGFGLEAGD
EECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCC
RIGLLGPNGAGKSTLVKTLVGELAPLAGERSAHPDLRIGYFAQHTVESLHEGQSPMDHFR
EEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCHHHHHH
ELSPDGANQAFRDFLGKWNFAGDRAFEVVDGFSGGERARLALALIAWQQPNVLLLDEPTN
HCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHEEEEEEEECCCCEEEEECCCC
HLDLEMREALAEALSDFEGAIVMVSHDRHLIGLVCDSFWRVADGVVEPFAGDLDEYAAWL
CCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RSRPAAQGTKQKMAEVAPTPPPPTKPLPPKKAVNPHKLASAEKRVGELEAALAALDRELA
HCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
NPGNYADSEKMAVLGRDREATAQQLAEAETAWMELIDGA
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]