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The map label for this gene is nahA [H]

Identifier: 21243801

GI number: 21243801

Start: 3598474

End: 3601005

Strand: Direct

Name: nahA [H]

Synonym: XAC3074

Alternate gene names: 21243801

Gene position: 3598474-3601005 (Clockwise)

Preceding gene: 21243800

Following gene: 21243802

Centisome position: 69.53

GC content: 66.23

Gene sequence:

>2532_bases
GTGCGCCAGTCACTGCGTCTTCCGACACGGCTTTGCTACTGTGCGTGGCTGCCGTGTACCGCCGCCACATCGGGATCTGA
TTGCATGATGTCGAACTCCGCACCCACCGCACGCCTGACAGCCGTCTCGCCGTTATCCTCGCGCCTGCTTGCGCTCGCAT
TCGCGGCAGCGTCGCTGGCCGGTTGCGGTCAACGAGCGCCAGGCACCTCGCCGGCCGTTGCAACCGCGGGCGCACCTGCT
GCAGCCGCAAACACTGCGGGTATCGCGTTGCCGCTGATTCCTGCGGCAGTGGAGGTCAAACGCGGTAGCGGCAGCTTCAC
GGTGGGCGCCGGCACGGTGATCTCGATCGTGCCCGGCGATGCCGATGCACGCCGCAGTGCCGAACATCTGGCCGATCTGC
TGCAACGCACACGCGGGCTGCGGTTGGAAGTGCGCGCCGAAACCAGTGCCTCGCCGGGCAGCATCCGCCTGGAGCGCAGC
GCGCAGGCGCCGGTAGGGCATAAAGAAGGTTACAGCCTGGAAGCCGATGCCAAGGGCGTGCGCATCGCCGCGCGCGATGG
CGCCGGCTTGTTGTATGGCGCAATCAGCGCCTGGCAATTGATGACACCGGATGCGCGCAAGGGCGAGGTCCAGGTCCCGG
CGGTGGCGATCCGCGACTGGCCGCGTTTCAGCTGGCGCGGCCAGCACCTGGATGTGGCCCGGCATTTCCATGATGTGGAC
ACGGTCAAGCATGTGCTCGATACGATGGCCCTGCACAAGCTCAACGTGCTGCATTGGCATCTCACCGATGATCAGGGTTG
GCGTATCGAGATCAAGCGCTATCCCAAGCTCACCGAGGTGGGCGCATGGCGCACACCGCCCGGCGCCGGCCAGCACGGCA
CGCCACAGCGGTATGGCGGCTTCTACACCCAGGAACAGATCAGCGAGATCGTCGCCTATGCGGCGCGTCTGCACATCACC
GTGCTGCCCGAACTGGACATGCCCGGCCATGCACAGGCAGCCGTTGCTGCCTACCCCGAAGAAGTGGGCGTACCCGGCGC
ACGCACGCAGGTGGGCGTGGATTGGGGCGTCAACCCGTATCTGTTCAACACCAGCGAACGCAGCCTGACCTTCATCACCA
ATGTACTGGACGAGGTGCTGACCTTGTTCCCGTCGACCTACATCCACATCGGTGGCGATGAGGCGGTGAAGGATCAGTGG
GAAGCCTCGCCGGCGGTGCGCGCGCAGATGCGCAAGCTCGGGGTCAAGGACGCGCACGCGATGCAGGGCTGGTTCAACGA
ACAACTGGCGGCCTACCTCACCCAGTACGGCCGGCGCATGATCGGTTGGGATGAAATTCTCGAAGGCGGCGTGCCGGCGA
GTGCGTCGGTGATGTCGTGGCGCGGCATCGAAGGCGCAGTGACCGCAGCACAGCAAGGCCACGATGTGGTGCTGGCGCCG
GGCGACTGGCTGTATCTGGACAACCTGCAGACCACCCGCAGCGACGAACCGAACGGCCGCCTGACGGTGTTGCCGCTGTC
GAAGGTCTACGCATTCGACCCGGTGCCGGCCGAGCTCAGCGCCGAACAGGCCGGGCATGTACTGGGCGCACAAGGCGCGT
TGTGGTCCGAATACATCCCCTCGCGCTGGCACGTGGATCACGCACTGTTTCCGCGTCTTGCTGCGGTAGCGGAAGTGACC
TGGTCACCGCCGGCAGCGCGCAACTGGAACAGCTTCCTGACGCGCATGCCGGCGCAGCTGCAGCGCTACAAGGCGCTGGG
CATCGACTACAGCGATGGCGCATTCGCTGCCGATATCGCCCTGGAAGGCGGACCCAATCCGGTGCTCGCCGGTGGGCCGG
CCAAGGTAGCGCTGAGCACGCAAGCCGGCGCGGGCACGCTTCACTACACCGTCGACGGCAGCGAGCCAACGCCGGCATCG
CCGCGCTACAACGCGCCGTTTACGATTCGATTGCCGACGACGGTCAAGGCGACTGCGTTCGATGCCAACGGAACGCCGCT
GGCGGCCACGCGTCGCCGCAGCTTCGATCGCGCGAGTTTGTTGCGGGTGGATACGCAGGGATTGCAGCACTGCGTTGAAA
CCGGCGCGCTCGGCTTGCGCCTGCCGCTGTTGCCGGAGATGACCGGCGCCGACACGCCGGTGTACAACGTCGACCTGTTC
CGTGCCTGCCGCCTGTATCCGCAGGCACGGCTGGACGGTATCGGCGCAATCCGCATCGAAGCCGCACGCTTGCCCAACAA
CTTCGGACTGGCGCACGAGCAATCCAAGGTCGTGCAATACCCAGCCAAAACCCGCGGCGGTGAGCTGGAAGTGCGTCAGG
GCTGCGACGGCGAGTTGATCGCCAGCGTGCAGCTGCCGCGCAGCGACACCCTGGGCGAGCAATTCACCCTGGAAACCGCA
CTGCCTGCACGCACCGGCGTCCACGATCTGTGCCTGCGCTTCACCGCGCCGATTCGCGGCCCCCTGTACGCCATCGGCGC
CGTTCAATTGATTGAAACCACTGCGCAGGCGCCCCCCGCCGCCACGCGCTGA

Upstream 100 bases:

>100_bases
ATTCCGGTTCCAGCGTCGCCCGCGCCGGTTTTGCAGCGACCGACGCCCCTGACGTGATCGCATGACCACGCAGCGCCCGC
GCTGCGCAGCGGGACGAAGC

Downstream 100 bases:

>100_bases
GCCACCCTAGGAGAGTCACGCATGCCCCTGTCCTGTCATCGTGTTGTTCCCACCCCCGCCCGTCTCGGGCTTGCCCTGGC
CTTGGCCATCTCGCAGGCCT

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 843; Mature: 843

Protein sequence:

>843_residues
MRQSLRLPTRLCYCAWLPCTAATSGSDCMMSNSAPTARLTAVSPLSSRLLALAFAAASLAGCGQRAPGTSPAVATAGAPA
AAANTAGIALPLIPAAVEVKRGSGSFTVGAGTVISIVPGDADARRSAEHLADLLQRTRGLRLEVRAETSASPGSIRLERS
AQAPVGHKEGYSLEADAKGVRIAARDGAGLLYGAISAWQLMTPDARKGEVQVPAVAIRDWPRFSWRGQHLDVARHFHDVD
TVKHVLDTMALHKLNVLHWHLTDDQGWRIEIKRYPKLTEVGAWRTPPGAGQHGTPQRYGGFYTQEQISEIVAYAARLHIT
VLPELDMPGHAQAAVAAYPEEVGVPGARTQVGVDWGVNPYLFNTSERSLTFITNVLDEVLTLFPSTYIHIGGDEAVKDQW
EASPAVRAQMRKLGVKDAHAMQGWFNEQLAAYLTQYGRRMIGWDEILEGGVPASASVMSWRGIEGAVTAAQQGHDVVLAP
GDWLYLDNLQTTRSDEPNGRLTVLPLSKVYAFDPVPAELSAEQAGHVLGAQGALWSEYIPSRWHVDHALFPRLAAVAEVT
WSPPAARNWNSFLTRMPAQLQRYKALGIDYSDGAFAADIALEGGPNPVLAGGPAKVALSTQAGAGTLHYTVDGSEPTPAS
PRYNAPFTIRLPTTVKATAFDANGTPLAATRRRSFDRASLLRVDTQGLQHCVETGALGLRLPLLPEMTGADTPVYNVDLF
RACRLYPQARLDGIGAIRIEAARLPNNFGLAHEQSKVVQYPAKTRGGELEVRQGCDGELIASVQLPRSDTLGEQFTLETA
LPARTGVHDLCLRFTAPIRGPLYAIGAVQLIETTAQAPPAATR

Sequences:

>Translated_843_residues
MRQSLRLPTRLCYCAWLPCTAATSGSDCMMSNSAPTARLTAVSPLSSRLLALAFAAASLAGCGQRAPGTSPAVATAGAPA
AAANTAGIALPLIPAAVEVKRGSGSFTVGAGTVISIVPGDADARRSAEHLADLLQRTRGLRLEVRAETSASPGSIRLERS
AQAPVGHKEGYSLEADAKGVRIAARDGAGLLYGAISAWQLMTPDARKGEVQVPAVAIRDWPRFSWRGQHLDVARHFHDVD
TVKHVLDTMALHKLNVLHWHLTDDQGWRIEIKRYPKLTEVGAWRTPPGAGQHGTPQRYGGFYTQEQISEIVAYAARLHIT
VLPELDMPGHAQAAVAAYPEEVGVPGARTQVGVDWGVNPYLFNTSERSLTFITNVLDEVLTLFPSTYIHIGGDEAVKDQW
EASPAVRAQMRKLGVKDAHAMQGWFNEQLAAYLTQYGRRMIGWDEILEGGVPASASVMSWRGIEGAVTAAQQGHDVVLAP
GDWLYLDNLQTTRSDEPNGRLTVLPLSKVYAFDPVPAELSAEQAGHVLGAQGALWSEYIPSRWHVDHALFPRLAAVAEVT
WSPPAARNWNSFLTRMPAQLQRYKALGIDYSDGAFAADIALEGGPNPVLAGGPAKVALSTQAGAGTLHYTVDGSEPTPAS
PRYNAPFTIRLPTTVKATAFDANGTPLAATRRRSFDRASLLRVDTQGLQHCVETGALGLRLPLLPEMTGADTPVYNVDLF
RACRLYPQARLDGIGAIRIEAARLPNNFGLAHEQSKVVQYPAKTRGGELEVRQGCDGELIASVQLPRSDTLGEQFTLETA
LPARTGVHDLCLRFTAPIRGPLYAIGAVQLIETTAQAPPAATR
>Mature_843_residues
MRQSLRLPTRLCYCAWLPCTAATSGSDCMMSNSAPTARLTAVSPLSSRLLALAFAAASLAGCGQRAPGTSPAVATAGAPA
AAANTAGIALPLIPAAVEVKRGSGSFTVGAGTVISIVPGDADARRSAEHLADLLQRTRGLRLEVRAETSASPGSIRLERS
AQAPVGHKEGYSLEADAKGVRIAARDGAGLLYGAISAWQLMTPDARKGEVQVPAVAIRDWPRFSWRGQHLDVARHFHDVD
TVKHVLDTMALHKLNVLHWHLTDDQGWRIEIKRYPKLTEVGAWRTPPGAGQHGTPQRYGGFYTQEQISEIVAYAARLHIT
VLPELDMPGHAQAAVAAYPEEVGVPGARTQVGVDWGVNPYLFNTSERSLTFITNVLDEVLTLFPSTYIHIGGDEAVKDQW
EASPAVRAQMRKLGVKDAHAMQGWFNEQLAAYLTQYGRRMIGWDEILEGGVPASASVMSWRGIEGAVTAAQQGHDVVLAP
GDWLYLDNLQTTRSDEPNGRLTVLPLSKVYAFDPVPAELSAEQAGHVLGAQGALWSEYIPSRWHVDHALFPRLAAVAEVT
WSPPAARNWNSFLTRMPAQLQRYKALGIDYSDGAFAADIALEGGPNPVLAGGPAKVALSTQAGAGTLHYTVDGSEPTPAS
PRYNAPFTIRLPTTVKATAFDANGTPLAATRRRSFDRASLLRVDTQGLQHCVETGALGLRLPLLPEMTGADTPVYNVDLF
RACRLYPQARLDGIGAIRIEAARLPNNFGLAHEQSKVVQYPAKTRGGELEVRQGCDGELIASVQLPRSDTLGEQFTLETA
LPARTGVHDLCLRFTAPIRGPLYAIGAVQLIETTAQAPPAATR

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI189181666, Length=410, Percent_Identity=28.5365853658537, Blast_Score=150, Evalue=5e-36,
Organism=Homo sapiens, GI4504373, Length=443, Percent_Identity=26.410835214447, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17569815, Length=415, Percent_Identity=29.3975903614458, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24657468, Length=478, Percent_Identity=28.2426778242678, Blast_Score=143, Evalue=6e-34,
Organism=Drosophila melanogaster, GI17647501, Length=478, Percent_Identity=28.2426778242678, Blast_Score=143, Evalue=6e-34,
Organism=Drosophila melanogaster, GI281365639, Length=478, Percent_Identity=28.2426778242678, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24657474, Length=478, Percent_Identity=28.2426778242678, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI17933586, Length=430, Percent_Identity=27.4418604651163, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI45551090, Length=432, Percent_Identity=24.537037037037, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24653074, Length=432, Percent_Identity=24.537037037037, Blast_Score=99, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 90456; Mature: 90456

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQSLRLPTRLCYCAWLPCTAATSGSDCMMSNSAPTARLTAVSPLSSRLLALAFAAASLA
CCCCCCCHHHHHHHEECCCCCCCCCCCEEECCCCCCEEEEEECHHHHHHHHHHHHHHHHH
GCGQRAPGTSPAVATAGAPAAAANTAGIALPLIPAAVEVKRGSGSFTVGAGTVISIVPGD
CCCCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCEEEEECCCCCEEECCCEEEEEECCC
ADARRSAEHLADLLQRTRGLRLEVRAETSASPGSIRLERSAQAPVGHKEGYSLEADAKGV
CHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCEECCCCCE
RIAARDGAGLLYGAISAWQLMTPDARKGEVQVPAVAIRDWPRFSWRGQHLDVARHFHDVD
EEEECCCCEEEEEHHHHHEEECCCCCCCEEECCEEEECCCCCCCCCCCCHHHHHHHHHHH
TVKHVLDTMALHKLNVLHWHLTDDQGWRIEIKRYPKLTEVGAWRTPPGAGQHGTPQRYGG
HHHHHHHHHHHHHEEEEEEEEECCCCCEEEEECCCCHHHCCCCCCCCCCCCCCCCHHHCC
FYTQEQISEIVAYAARLHITVLPELDMPGHAQAAVAAYPEEVGVPGARTQVGVDWGVNPY
CCCHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHCCHHHHCCCCCCEEEEECCCCCCE
LFNTSERSLTFITNVLDEVLTLFPSTYIHIGGDEAVKDQWEASPAVRAQMRKLGVKDAHA
EECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCHHHHHHHHHCCCCHHHH
MQGWFNEQLAAYLTQYGRRMIGWDEILEGGVPASASVMSWRGIEGAVTAAQQGHDVVLAP
HHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEEECCCCHHHHHHCCCCEEEECC
GDWLYLDNLQTTRSDEPNGRLTVLPLSKVYAFDPVPAELSAEQAGHVLGAQGALWSEYIP
CCEEEECCCCCCCCCCCCCCEEEEEHHHEEECCCCCCCCCHHHCCCEECCCCCHHHHHCC
SRWHVDHALFPRLAAVAEVTWSPPAARNWNSFLTRMPAQLQRYKALGIDYSDGAFAADIA
CCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
LEGGPNPVLAGGPAKVALSTQAGAGTLHYTVDGSEPTPASPRYNAPFTIRLPTTVKATAF
ECCCCCCEEECCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCEEEEEEE
DANGTPLAATRRRSFDRASLLRVDTQGLQHCVETGALGLRLPLLPEMTGADTPVYNVDLF
CCCCCCCHHHHHCCCCHHHHEEECHHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEHHHH
RACRLYPQARLDGIGAIRIEAARLPNNFGLAHEQSKVVQYPAKTRGGELEVRQGCDGELI
HHHHHCCHHHCCCCEEEEEEEECCCCCCCCCCCCCHHEECCCCCCCCEEEECCCCCCCEE
ASVQLPRSDTLGEQFTLETALPARTGVHDLCLRFTAPIRGPLYAIGAVQLIETTAQAPPA
EEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
ATR
CCC
>Mature Secondary Structure
MRQSLRLPTRLCYCAWLPCTAATSGSDCMMSNSAPTARLTAVSPLSSRLLALAFAAASLA
CCCCCCCHHHHHHHEECCCCCCCCCCCEEECCCCCCEEEEEECHHHHHHHHHHHHHHHHH
GCGQRAPGTSPAVATAGAPAAAANTAGIALPLIPAAVEVKRGSGSFTVGAGTVISIVPGD
CCCCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCEEEEECCCCCEEECCCEEEEEECCC
ADARRSAEHLADLLQRTRGLRLEVRAETSASPGSIRLERSAQAPVGHKEGYSLEADAKGV
CHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCEECCCCCE
RIAARDGAGLLYGAISAWQLMTPDARKGEVQVPAVAIRDWPRFSWRGQHLDVARHFHDVD
EEEECCCCEEEEEHHHHHEEECCCCCCCEEECCEEEECCCCCCCCCCCCHHHHHHHHHHH
TVKHVLDTMALHKLNVLHWHLTDDQGWRIEIKRYPKLTEVGAWRTPPGAGQHGTPQRYGG
HHHHHHHHHHHHHEEEEEEEEECCCCCEEEEECCCCHHHCCCCCCCCCCCCCCCCHHHCC
FYTQEQISEIVAYAARLHITVLPELDMPGHAQAAVAAYPEEVGVPGARTQVGVDWGVNPY
CCCHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHCCHHHHCCCCCCEEEEECCCCCCE
LFNTSERSLTFITNVLDEVLTLFPSTYIHIGGDEAVKDQWEASPAVRAQMRKLGVKDAHA
EECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCHHHHHHHHHCCCCHHHH
MQGWFNEQLAAYLTQYGRRMIGWDEILEGGVPASASVMSWRGIEGAVTAAQQGHDVVLAP
HHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEEECCCCHHHHHHCCCCEEEECC
GDWLYLDNLQTTRSDEPNGRLTVLPLSKVYAFDPVPAELSAEQAGHVLGAQGALWSEYIP
CCEEEECCCCCCCCCCCCCCEEEEEHHHEEECCCCCCCCCHHHCCCEECCCCCHHHHHCC
SRWHVDHALFPRLAAVAEVTWSPPAARNWNSFLTRMPAQLQRYKALGIDYSDGAFAADIA
CCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
LEGGPNPVLAGGPAKVALSTQAGAGTLHYTVDGSEPTPASPRYNAPFTIRLPTTVKATAF
ECCCCCCEEECCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCEEEEEEE
DANGTPLAATRRRSFDRASLLRVDTQGLQHCVETGALGLRLPLLPEMTGADTPVYNVDLF
CCCCCCCHHHHHCCCCHHHHEEECHHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEHHHH
RACRLYPQARLDGIGAIRIEAARLPNNFGLAHEQSKVVQYPAKTRGGELEVRQGCDGELI
HHHHHCCHHHCCCCEEEEEEEECCCCCCCCCCCCCHHEECCCCCCCCEEEECCCCCCCEE
ASVQLPRSDTLGEQFTLETALPARTGVHDLCLRFTAPIRGPLYAIGAVQLIETTAQAPPA
EEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
ATR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]