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The map label for this gene is capD [H]

Identifier: 21243028

GI number: 21243028

Start: 2683045

End: 2684952

Strand: Reverse

Name: capD [H]

Synonym: XAC2293

Alternate gene names: 21243028

Gene position: 2684952-2683045 (Counterclockwise)

Preceding gene: 21243029

Following gene: 21243027

Centisome position: 51.88

GC content: 63.57

Gene sequence:

>1908_bases
ATGATTTCCTGGCGTGACCGTTTGACCAAGGCGCTGCCGCAGATAGCGGTCGTGGTACATGACCTGCTGATGGTGTGGGT
GTGCTGGCAGCTGCTGCATGCCGGCCGCTACTCGATGCTACGCGACGCGCCGAATCTGCCGCTGTGGGACTGGCGCACAG
CGGTGGTGTTGGTGGCGCAGGGCCTGGTGTTCTGGAAGATGGGGTTGTACCGCGGGTTGTGGCGCTTCGCCTCGGTGCCG
GACCTGTGGAACATCTTCAAGGCGAGTTTTCTTGGACTCGTCGCAATCGTGCTGGCGCTGGCGTACGACCGTCTGGATGG
CGTGCCGCTGTCGGTGCTGGTGGTCTATCCATTTGCGTTGTCGGCGCTACTTGGCACGCCGCGTCTGCTGTATCGCGCAT
GGAAGGATTATCAGATTGCGCACTCCGGCGATGCCGCGCAGCGCGTGCTGATCCTTGGCGCTGGTCGGGCTGCTGAAGGG
TTGGTGCGCGATCTGCGTCGCACCGGCGCATTTGTGCCGGTCGGGTATTTGGACGACGCCAATAACCTGCATGGGGCCAA
GATCCAGGGTCTCAATGTGCTGGGCAATCTGGATCAGGCCGCCGCCATTGCCAAGGAGACCGCCGCCAAATTGCTGGTGA
TCGCAATCCCGTCGCTGGACGCCTCCGGCATGCAGCGCGTCGTGGCGATCTGCGAAAGCACCGGCCTGCCGTTCCGCATG
GTGCCCAAGCTGATCAACGTGCTGGAGGGGCGCTCGTTGCCGGGCGAGTTGAAGGAGGTCGCGATCGAGGACCTGCTCAA
CCGCAAGCCGGTCACGCCCGACTGGCGCCTGATCCGCGACTGGCTGACCAACAAGACCGTGATGGTGACCGGCGCCGGCG
GCTCGATCGGTTCGGAAGTCTGCCGCCAGTGCGCGCGCCACGGCGCGCGTCGGATCGTGCTGCTGGAAATCGACGAGCTG
GCGCTACTGACCATCGACTCGGATCTACGCCGGCTGTTCCCGGATATCGAGGTGGTGCGAGTGTTAGGCGATTGCGGCGA
CCCGGCGGTCGTGGCGCATGCGTTGAACACTGCCACGCCGGACGCGGTCTTCCATGCAGCCGCGTACAAGCAGGTGCCGT
TGCTGGAAGAGCAGTTGCGCGAGGCGGTGCGCAACAACGTCCTGGCGACCGAGAACGTGGCGCGCGCCTGCCAGCGTGCA
CGTATCGAAACCTTCGTCTTCATCTCCACCGACAAGGCGGTCGAGCCGGTCAACGTGCTGGGCGCAAGTAAGCGCTATGC
AGAAATGATCTGCCAAAGCCTTGACGCGCGCGATGCGCCGACGCGCTTCATCACCGTGCGCTTCGGCAACGTGCTGGATT
CGGCCGGCAGCGTGGTGCCGTTGTTCCGCGAACAGATCCGCCAGGGCGGCCCGGTAACCGTGACGCATCCGGATGTGACG
CGTTACTTCATGACCATCCCCGAAGCCTGCCAGTTGGTCATCCAGGCGGCTGCATCTGCGTCGCATGGTGCGATCTATAC
ACTGGACATGGGCGAGCCGGTGCCGATTCGACTGCTTGCCGAGCAGATGATCCGTCTGGCCGGCAAGCAGCCAGGCAAGG
ACGTGGCGATTCTCTATACCGGCCTGCGTCCGGGCGAGAAGTTGCACGAGACGCTGTTCTATTCCGACGAGGCCTATCGC
CCCACCGCGCACCCCAAGATCCTGGAGGCCGGTGTGCGCGAGTTCTCGCATGAGCAGGTGCTGCAGCTGGTGATGCGCTT
GCGCGAGGCCGTTAACCGCTACGACATCAAAGCGATGGAGACTGTATTGGGCAGCCTGATGCCGGATTTCGCGGCTGCTC
GACGGAAAGTCGACGCGCGATCTGATACGGTCGTTCCATTCCCCGCACGTGAGGTCAGAAGACTGTAA

Upstream 100 bases:

>100_bases
TGGCTGCAGGTGTCCGGCGCGCTGGTATGGGGCATGGGCGCCACTGCGATCTGGCATTTTCTGCGCGATGGATTGCGCAA
TTCCTGACTAATGGACTTTT

Downstream 100 bases:

>100_bases
TGAGCCAGCGTATTCGCAAGGCCGTATTCCCCGTCGCAGGTCTTGGGACCCGCTTTCTTCCGGCAACCAAGACAGTGCCG
AAAGAAATGCTGCCAATCAT

Product: dehydratase protein

Products: UDPglucoseal [C]

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MISWRDRLTKALPQIAVVVHDLLMVWVCWQLLHAGRYSMLRDAPNLPLWDWRTAVVLVAQGLVFWKMGLYRGLWRFASVP
DLWNIFKASFLGLVAIVLALAYDRLDGVPLSVLVVYPFALSALLGTPRLLYRAWKDYQIAHSGDAAQRVLILGAGRAAEG
LVRDLRRTGAFVPVGYLDDANNLHGAKIQGLNVLGNLDQAAAIAKETAAKLLVIAIPSLDASGMQRVVAICESTGLPFRM
VPKLINVLEGRSLPGELKEVAIEDLLNRKPVTPDWRLIRDWLTNKTVMVTGAGGSIGSEVCRQCARHGARRIVLLEIDEL
ALLTIDSDLRRLFPDIEVVRVLGDCGDPAVVAHALNTATPDAVFHAAAYKQVPLLEEQLREAVRNNVLATENVARACQRA
RIETFVFISTDKAVEPVNVLGASKRYAEMICQSLDARDAPTRFITVRFGNVLDSAGSVVPLFREQIRQGGPVTVTHPDVT
RYFMTIPEACQLVIQAAASASHGAIYTLDMGEPVPIRLLAEQMIRLAGKQPGKDVAILYTGLRPGEKLHETLFYSDEAYR
PTAHPKILEAGVREFSHEQVLQLVMRLREAVNRYDIKAMETVLGSLMPDFAAARRKVDARSDTVVPFPAREVRRL

Sequences:

>Translated_635_residues
MISWRDRLTKALPQIAVVVHDLLMVWVCWQLLHAGRYSMLRDAPNLPLWDWRTAVVLVAQGLVFWKMGLYRGLWRFASVP
DLWNIFKASFLGLVAIVLALAYDRLDGVPLSVLVVYPFALSALLGTPRLLYRAWKDYQIAHSGDAAQRVLILGAGRAAEG
LVRDLRRTGAFVPVGYLDDANNLHGAKIQGLNVLGNLDQAAAIAKETAAKLLVIAIPSLDASGMQRVVAICESTGLPFRM
VPKLINVLEGRSLPGELKEVAIEDLLNRKPVTPDWRLIRDWLTNKTVMVTGAGGSIGSEVCRQCARHGARRIVLLEIDEL
ALLTIDSDLRRLFPDIEVVRVLGDCGDPAVVAHALNTATPDAVFHAAAYKQVPLLEEQLREAVRNNVLATENVARACQRA
RIETFVFISTDKAVEPVNVLGASKRYAEMICQSLDARDAPTRFITVRFGNVLDSAGSVVPLFREQIRQGGPVTVTHPDVT
RYFMTIPEACQLVIQAAASASHGAIYTLDMGEPVPIRLLAEQMIRLAGKQPGKDVAILYTGLRPGEKLHETLFYSDEAYR
PTAHPKILEAGVREFSHEQVLQLVMRLREAVNRYDIKAMETVLGSLMPDFAAARRKVDARSDTVVPFPAREVRRL
>Mature_635_residues
MISWRDRLTKALPQIAVVVHDLLMVWVCWQLLHAGRYSMLRDAPNLPLWDWRTAVVLVAQGLVFWKMGLYRGLWRFASVP
DLWNIFKASFLGLVAIVLALAYDRLDGVPLSVLVVYPFALSALLGTPRLLYRAWKDYQIAHSGDAAQRVLILGAGRAAEG
LVRDLRRTGAFVPVGYLDDANNLHGAKIQGLNVLGNLDQAAAIAKETAAKLLVIAIPSLDASGMQRVVAICESTGLPFRM
VPKLINVLEGRSLPGELKEVAIEDLLNRKPVTPDWRLIRDWLTNKTVMVTGAGGSIGSEVCRQCARHGARRIVLLEIDEL
ALLTIDSDLRRLFPDIEVVRVLGDCGDPAVVAHALNTATPDAVFHAAAYKQVPLLEEQLREAVRNNVLATENVARACQRA
RIETFVFISTDKAVEPVNVLGASKRYAEMICQSLDARDAPTRFITVRFGNVLDSAGSVVPLFREQIRQGGPVTVTHPDVT
RYFMTIPEACQLVIQAAASASHGAIYTLDMGEPVPIRLLAEQMIRLAGKQPGKDVAILYTGLRPGEKLHETLFYSDEAYR
PTAHPKILEAGVREFSHEQVLQLVMRLREAVNRYDIKAMETVLGSLMPDFAAARRKVDARSDTVVPFPAREVRRL

Specific function: Required for the biosynthesis of type 1 capsular polysaccharide [H]

COG id: COG1086

COG function: function code MG; Predicted nucleoside-diphosphate sugar epimerases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003869 [H]

Pfam domain/function: PF02719 Polysacc_synt_2 [H]

EC number: 5.1.3.2 [C]

Molecular weight: Translated: 70222; Mature: 70222

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISWRDRLTKALPQIAVVVHDLLMVWVCWQLLHAGRYSMLRDAPNLPLWDWRTAVVLVAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHH
GLVFWKMGLYRGLWRFASVPDLWNIFKASFLGLVAIVLALAYDRLDGVPLSVLVVYPFAL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
SALLGTPRLLYRAWKDYQIAHSGDAAQRVLILGAGRAAEGLVRDLRRTGAFVPVGYLDDA
HHHHCCHHHHHHHHCCCEEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCC
NNLHGAKIQGLNVLGNLDQAAAIAKETAAKLLVIAIPSLDASGMQRVVAICESTGLPFRM
CCCCCCEEECCHHHCCCHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHCCCCCHHH
VPKLINVLEGRSLPGELKEVAIEDLLNRKPVTPDWRLIRDWLTNKTVMVTGAGGSIGSEV
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHH
CRQCARHGARRIVLLEIDELALLTIDSDLRRLFPDIEVVRVLGDCGDPAVVAHALNTATP
HHHHHHCCCCEEEEEEECCEEEEEECHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCH
DAVFHAAAYKQVPLLEEQLREAVRNNVLATENVARACQRARIETFVFISTDKAVEPVNVL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHH
GASKRYAEMICQSLDARDAPTRFITVRFGNVLDSAGSVVPLFREQIRQGGPVTVTHPDVT
CCCHHHHHHHHHHCCCCCCCCEEEEEEECHHHHCCCCCHHHHHHHHHCCCCEEEECCHHH
RYFMTIPEACQLVIQAAASASHGAIYTLDMGEPVPIRLLAEQMIRLAGKQPGKDVAILYT
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEE
GLRPGEKLHETLFYSDEAYRPTAHPKILEAGVREFSHEQVLQLVMRLREAVNRYDIKAME
CCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TVLGSLMPDFAAARRKVDARSDTVVPFPAREVRRL
HHHHHHCHHHHHHHHHCCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MISWRDRLTKALPQIAVVVHDLLMVWVCWQLLHAGRYSMLRDAPNLPLWDWRTAVVLVAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHH
GLVFWKMGLYRGLWRFASVPDLWNIFKASFLGLVAIVLALAYDRLDGVPLSVLVVYPFAL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
SALLGTPRLLYRAWKDYQIAHSGDAAQRVLILGAGRAAEGLVRDLRRTGAFVPVGYLDDA
HHHHCCHHHHHHHHCCCEEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCC
NNLHGAKIQGLNVLGNLDQAAAIAKETAAKLLVIAIPSLDASGMQRVVAICESTGLPFRM
CCCCCCEEECCHHHCCCHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHCCCCCHHH
VPKLINVLEGRSLPGELKEVAIEDLLNRKPVTPDWRLIRDWLTNKTVMVTGAGGSIGSEV
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHH
CRQCARHGARRIVLLEIDELALLTIDSDLRRLFPDIEVVRVLGDCGDPAVVAHALNTATP
HHHHHHCCCCEEEEEEECCEEEEEECHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCH
DAVFHAAAYKQVPLLEEQLREAVRNNVLATENVARACQRARIETFVFISTDKAVEPVNVL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHH
GASKRYAEMICQSLDARDAPTRFITVRFGNVLDSAGSVVPLFREQIRQGGPVTVTHPDVT
CCCHHHHHHHHHHCCCCCCCCEEEEEEECHHHHCCCCCHHHHHHHHHCCCCEEEECCHHH
RYFMTIPEACQLVIQAAASASHGAIYTLDMGEPVPIRLLAEQMIRLAGKQPGKDVAILYT
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEE
GLRPGEKLHETLFYSDEAYRPTAHPKILEAGVREFSHEQVLQLVMRLREAVNRYDIKAME
CCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TVLGSLMPDFAAARRKVDARSDTVVPFPAREVRRL
HHHHHHCHHHHHHHHHCCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDPglucose [C]

Specific reaction: UDPglucose <==> UDPglucoseal [C]

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961465 [H]