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The map label for this gene is rfb303 [H]

Identifier: 21243029

GI number: 21243029

Start: 2684966

End: 2685934

Strand: Reverse

Name: rfb303 [H]

Synonym: XAC2294

Alternate gene names: 21243029

Gene position: 2685934-2684966 (Counterclockwise)

Preceding gene: 21243030

Following gene: 21243028

Centisome position: 51.9

GC content: 64.5

Gene sequence:

>969_bases
ATGGTGTGGCTGTGGTGCGTGCTGCACCTGCTGGTCGCGGCACTGGGGACCTGGGGGCTGCGGCGCTATGCCTTGCACCG
CCGCCTGCTCGATCATCCCGGTGAACGGCGTAGCCACGTGGTGGCAACCCCGCGCGGCGGCGGCATGGCGATTGTGGCGG
CGATCTTGCTGGGCTGCGTTGCAGCTTGCGCGCTATGGCCGACATCTCGGCTGACGGTCTGCTGGTTCGCGGCGGGCTTG
GTCGCAGTGGCCGGGGTGGGCTGGTGGGACGACCACCGTCCGCTTTCGGCAAGGCTGCGGTTCTCGATCCACCTGGCTGC
CTCGGTGGCATTGGGCGCCTTGGTCTGGCATGGCACAGGCAGCGTGTGGGATGGAGTGCTGACTGCCGCTGCGTCCGTGA
TGTTGATCAATGTCTGGAATTTCATGGATGGCATCAACGGTCTGGCCAGCACCCAGGCGGCATTGGCCGCCCTGGGATTC
TCGCTGGTAGCGCCTGTCGGTTGGTCGTGGGCAGGTCTGGCGGTTGCCGCAGCGTGCCTCGGGTTTGTGCCGTTCAACTT
CCCACGTGCGCGCATCTTCATGGGCGATGGCGGCAGCGGTGCGCTCGGCTATGTGCTGGCGGCGCTATTGGCGCTGAACG
TCGCAGGTGGTCAGGTGAGCTGGTGGATCAGCTGGCTCCCGTTGACGGCCTTTCTTGTAGACGCCGGCTTCACACTGCTT
GCTCGCATGCTCTCCGGGCAACGCTGGTGGGAGCCGCATGCCCAGCACGTGTACCAACGACTGGCGCGTCGTCTTGAGAC
GCACGTTCCGGTAACGGGCGTTTATTTCGCTTTCAGCCTCATTGCCGTCTGCTTGTACCTGTTAATCCGTCATGATCCGT
TCTGGCTGCAGGTGTCCGGCGCGCTGGTATGGGGCATGGGCGCCACTGCGATCTGGCATTTTCTGCGCGATGGATTGCGC
AATTCCTGA

Upstream 100 bases:

>100_bases
GCACACGCTGCGGCTTTGGTGCCAAGACGCATCACTGGCAATGCCCGAGCTGCAAGGAATGGGGTACGGTCAAGCCGCTG
TTGAACTACGCGGTGGTCTG

Downstream 100 bases:

>100_bases
CTAATGGACTTTTATGATTTCCTGGCGTGACCGTTTGACCAAGGCGCTGCCGCAGATAGCGGTCGTGGTACATGACCTGC
TGATGGTGTGGGTGTGCTGG

Product: lipopolysaccharide core biosynthesis protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MVWLWCVLHLLVAALGTWGLRRYALHRRLLDHPGERRSHVVATPRGGGMAIVAAILLGCVAACALWPTSRLTVCWFAAGL
VAVAGVGWWDDHRPLSARLRFSIHLAASVALGALVWHGTGSVWDGVLTAAASVMLINVWNFMDGINGLASTQAALAALGF
SLVAPVGWSWAGLAVAAACLGFVPFNFPRARIFMGDGGSGALGYVLAALLALNVAGGQVSWWISWLPLTAFLVDAGFTLL
ARMLSGQRWWEPHAQHVYQRLARRLETHVPVTGVYFAFSLIAVCLYLLIRHDPFWLQVSGALVWGMGATAIWHFLRDGLR
NS

Sequences:

>Translated_322_residues
MVWLWCVLHLLVAALGTWGLRRYALHRRLLDHPGERRSHVVATPRGGGMAIVAAILLGCVAACALWPTSRLTVCWFAAGL
VAVAGVGWWDDHRPLSARLRFSIHLAASVALGALVWHGTGSVWDGVLTAAASVMLINVWNFMDGINGLASTQAALAALGF
SLVAPVGWSWAGLAVAAACLGFVPFNFPRARIFMGDGGSGALGYVLAALLALNVAGGQVSWWISWLPLTAFLVDAGFTLL
ARMLSGQRWWEPHAQHVYQRLARRLETHVPVTGVYFAFSLIAVCLYLLIRHDPFWLQVSGALVWGMGATAIWHFLRDGLR
NS
>Mature_322_residues
MVWLWCVLHLLVAALGTWGLRRYALHRRLLDHPGERRSHVVATPRGGGMAIVAAILLGCVAACALWPTSRLTVCWFAAGL
VAVAGVGWWDDHRPLSARLRFSIHLAASVALGALVWHGTGSVWDGVLTAAASVMLINVWNFMDGINGLASTQAALAALGF
SLVAPVGWSWAGLAVAAACLGFVPFNFPRARIFMGDGGSGALGYVLAALLALNVAGGQVSWWISWLPLTAFLVDAGFTLL
ARMLSGQRWWEPHAQHVYQRLARRLETHVPVTGVYFAFSLIAVCLYLLIRHDPFWLQVSGALVWGMGATAIWHFLRDGLR
NS

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 34878; Mature: 34878

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWLWCVLHLLVAALGTWGLRRYALHRRLLDHPGERRSHVVATPRGGGMAIVAAILLGCV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
AACALWPTSRLTVCWFAAGLVAVAGVGWWDDHRPLSARLRFSIHLAASVALGALVWHGTG
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEEHHHHHHHHHHHHHCCCCC
SVWDGVLTAAASVMLINVWNFMDGINGLASTQAALAALGFSLVAPVGWSWAGLAVAAACL
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GFVPFNFPRARIFMGDGGSGALGYVLAALLALNVAGGQVSWWISWLPLTAFLVDAGFTLL
HHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
ARMLSGQRWWEPHAQHVYQRLARRLETHVPVTGVYFAFSLIAVCLYLLIRHDPFWLQVSG
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
ALVWGMGATAIWHFLRDGLRNS
EEEECCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVWLWCVLHLLVAALGTWGLRRYALHRRLLDHPGERRSHVVATPRGGGMAIVAAILLGCV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
AACALWPTSRLTVCWFAAGLVAVAGVGWWDDHRPLSARLRFSIHLAASVALGALVWHGTG
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEEHHHHHHHHHHHHHCCCCC
SVWDGVLTAAASVMLINVWNFMDGINGLASTQAALAALGFSLVAPVGWSWAGLAVAAACL
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GFVPFNFPRARIFMGDGGSGALGYVLAALLALNVAGGQVSWWISWLPLTAFLVDAGFTLL
HHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
ARMLSGQRWWEPHAQHVYQRLARRLETHVPVTGVYFAFSLIAVCLYLLIRHDPFWLQVSG
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
ALVWGMGATAIWHFLRDGLRNS
EEEECCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]