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The map label for this gene is galU [H]

Identifier: 21243027

GI number: 21243027

Start: 2682152

End: 2683045

Strand: Reverse

Name: galU [H]

Synonym: XAC2292

Alternate gene names: 21243027

Gene position: 2683045-2682152 (Counterclockwise)

Preceding gene: 21243028

Following gene: 21243026

Centisome position: 51.84

GC content: 61.86

Gene sequence:

>894_bases
ATGAGCCAGCGTATTCGCAAGGCCGTATTCCCCGTCGCAGGTCTTGGGACCCGCTTTCTTCCGGCAACCAAGACAGTGCC
GAAAGAAATGCTGCCAATCATCGACAAGCCATTGATTCAGTACGCCGTCGACGAAGCCATCCAGGCTGGTTGCGATACGC
TGATCTTCGTGACCAACCGCTATAAGCACTCCATCGCCGACTACTTCGACAAGGCCTATGAGCTCGAGCAGAAGCTGGAG
CGTGCAGGCAAGCTGGAGCAGCTGGAGCTTGTGCGCCATGCGCTGCCGGACGGCGTTCGCGCCATTTTTGTGACGCAGGC
GGAAGCGCTGGGTCTGGGTCATGCAGTGCTGTGTGCCAAGGCCGTTGTCGGTAACGAACCGTTCGCGGTGTTGCTGCCGG
ACGATCTGATGTGGAACCGCGGTGATGCTGCGCTGACCCAGATGGCCAACGTGGCGGAAGCCTCGGGCGGCAGCGTGATC
GCCGTGGAAGACGTGCCGCACGACAAGACCGCCAGCTACGGCATCGTTTCCACCGACGCATTCGACGGCCGCAAGGGCCG
CATCAACGCGATCGTCGAAAAGCCCAAGCCGGAAGTCGCGCCAAGCAACCTGGCCGTGGTCGGTCGTTACGTGCTGAGCC
CCAAGATCTTCGACCTGCTCGAAGCCACCGGTGCAGGCGCAGGCGGCGAAATCCAGCTCACCGATGCGATCGCCGAATTG
CTGAAGGAAGAGCAGGTCGATGCCTTCCGCTTCGAGGGTCGCCGTTTCGATTGCGGCGCGCATATCGGCCTGATCGAAGC
CACCGTGCATTTTGCGCTCGAGCACGAAAAGCATGGCGGCCCAGCGAAGGAAATCCTGCGCGAAGCACTGGCCCAGGCCG
ACGTGCGCGGCTGA

Upstream 100 bases:

>100_bases
TGGGCAGCCTGATGCCGGATTTCGCGGCTGCTCGACGGAAAGTCGACGCGCGATCTGATACGGTCGTTCCATTCCCCGCA
CGTGAGGTCAGAAGACTGTA

Downstream 100 bases:

>100_bases
TTGTTGCCTGATCGCTGTTTCTACGAACGACGCCAGCTGGCGTCGTTCGTCGTTTGGGAGCTTGTCGTACGCGTTGTCGC
GTCTGCAGAGCTCGGCTTGG

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSQRIRKAVFPVAGLGTRFLPATKTVPKEMLPIIDKPLIQYAVDEAIQAGCDTLIFVTNRYKHSIADYFDKAYELEQKLE
RAGKLEQLELVRHALPDGVRAIFVTQAEALGLGHAVLCAKAVVGNEPFAVLLPDDLMWNRGDAALTQMANVAEASGGSVI
AVEDVPHDKTASYGIVSTDAFDGRKGRINAIVEKPKPEVAPSNLAVVGRYVLSPKIFDLLEATGAGAGGEIQLTDAIAEL
LKEEQVDAFRFEGRRFDCGAHIGLIEATVHFALEHEKHGGPAKEILREALAQADVRG

Sequences:

>Translated_297_residues
MSQRIRKAVFPVAGLGTRFLPATKTVPKEMLPIIDKPLIQYAVDEAIQAGCDTLIFVTNRYKHSIADYFDKAYELEQKLE
RAGKLEQLELVRHALPDGVRAIFVTQAEALGLGHAVLCAKAVVGNEPFAVLLPDDLMWNRGDAALTQMANVAEASGGSVI
AVEDVPHDKTASYGIVSTDAFDGRKGRINAIVEKPKPEVAPSNLAVVGRYVLSPKIFDLLEATGAGAGGEIQLTDAIAEL
LKEEQVDAFRFEGRRFDCGAHIGLIEATVHFALEHEKHGGPAKEILREALAQADVRG
>Mature_296_residues
SQRIRKAVFPVAGLGTRFLPATKTVPKEMLPIIDKPLIQYAVDEAIQAGCDTLIFVTNRYKHSIADYFDKAYELEQKLER
AGKLEQLELVRHALPDGVRAIFVTQAEALGLGHAVLCAKAVVGNEPFAVLLPDDLMWNRGDAALTQMANVAEASGGSVIA
VEDVPHDKTASYGIVSTDAFDGRKGRINAIVEKPKPEVAPSNLAVVGRYVLSPKIFDLLEATGAGAGGEIQLTDAIAELL
KEEQVDAFRFEGRRFDCGAHIGLIEATVHFALEHEKHGGPAKEILREALAQADVRG

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. a glycolipid found in the membrane, which is also used as a membrane anchor for lipote

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=299, Percent_Identity=47.1571906354515, Blast_Score=244, Evalue=4e-66,
Organism=Escherichia coli, GI1788355, Length=297, Percent_Identity=42.0875420875421, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1788351, Length=285, Percent_Identity=26.3157894736842, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790224, Length=278, Percent_Identity=25.8992805755396, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI133931050, Length=255, Percent_Identity=30.1960784313725, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320148, Length=269, Percent_Identity=26.3940520446097, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21355443, Length=257, Percent_Identity=25.2918287937743, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644084, Length=257, Percent_Identity=25.2918287937743, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32102; Mature: 31971

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRIRKAVFPVAGLGTRFLPATKTVPKEMLPIIDKPLIQYAVDEAIQAGCDTLIFVTNR
CCHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECH
YKHSIADYFDKAYELEQKLERAGKLEQLELVRHALPDGVRAIFVTQAEALGLGHAVLCAK
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEHHHHHCCCHHHHHHH
AVVGNEPFAVLLPDDLMWNRGDAALTQMANVAEASGGSVIAVEDVPHDKTASYGIVSTDA
HHHCCCCEEEEECCHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEECCC
FDGRKGRINAIVEKPKPEVAPSNLAVVGRYVLSPKIFDLLEATGAGAGGEIQLTDAIAEL
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEHHHHHHH
LKEEQVDAFRFEGRRFDCGAHIGLIEATVHFALEHEKHGGPAKEILREALAQADVRG
HHHHCCHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQRIRKAVFPVAGLGTRFLPATKTVPKEMLPIIDKPLIQYAVDEAIQAGCDTLIFVTNR
CHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECH
YKHSIADYFDKAYELEQKLERAGKLEQLELVRHALPDGVRAIFVTQAEALGLGHAVLCAK
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEHHHHHCCCHHHHHHH
AVVGNEPFAVLLPDDLMWNRGDAALTQMANVAEASGGSVIAVEDVPHDKTASYGIVSTDA
HHHCCCCEEEEECCHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEECCC
FDGRKGRINAIVEKPKPEVAPSNLAVVGRYVLSPKIFDLLEATGAGAGGEIQLTDAIAEL
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEHHHHHHH
LKEEQVDAFRFEGRRFDCGAHIGLIEATVHFALEHEKHGGPAKEILREALAQADVRG
HHHHCCHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA