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The map label for this gene is hmsR [H]

Identifier: 21242555

GI number: 21242555

Start: 2083978

End: 2085231

Strand: Reverse

Name: hmsR [H]

Synonym: XAC1811

Alternate gene names: 21242555

Gene position: 2085231-2083978 (Counterclockwise)

Preceding gene: 21242556

Following gene: 21242554

Centisome position: 40.29

GC content: 64.67

Gene sequence:

>1254_bases
ATGACGACCAGCCTCCTACTGGCCGCCCTGTTCAACTTTGCGTTTTATTACCCGATCATCATGGCGTTCTTCTGGATGAT
CGGCGGCATCTACTACTACCTGCGCCGTGAGCGCGGCACGCACAGGCCATCCAAGCCACCGCCGATGGCCAGCGAGCCGT
TCGTCTCGATCCTGATGCCCTGCTACAACGAGGCCAAGCACGTTGCCGAAACCATCGCGGCGATGAGCGCGCAGCAGTAC
GCAGACTTCGAGATCATTGCCATCAACGACGGCAGCACCGACCGCACTGCCGAAGTACTCGACGACCTCACCCACCACCA
CCCGCGCCTGCGCGTGGTGCATCTGGAGCAGAACCACGGCAAGGCCAACGCGTTGCGCGTCGGCACGCTGGCCGCGCGCT
CGGACTATCTGGTGTGCGTGGACGCCGATGCAATCCTGGACCCGAACGCCACGCGCTGGATGGTCGGCCACCTGATCGCC
GGCCCACGCGTGGGCGGCGTTACCGGCAACCCGCGCGTGCGCAACCGCACCACACTGATGGGCCGCATGCAGGTAGGCGA
ATTTTCCGCCATCGTCGGGCTGATCAAGCGCGCGCAACGCGTGTACGGGCGGCTGTTTACCGTGTCTGGTGTGATCTGCG
CGTTCCGTCGCTCGGCGCTACATCACGTCGGCTTCTGGTCCGACAACATGGTGACCGAGGACATCGACATCTCCTGGCGT
CTGCAGCTGGACGGCTGGGATATCCGCTACGAACCCAATGCGTTGTGCTGGATCCTGATGCCGGAAACCTTTCGCGGCCT
GTGGATGCAGCGCCTGCGCTGGGCGCGCGGCGGTGTCGAGGTGTTGCTGAGCCACGGCCGCCGTGCGCTGGCATGGCGCA
GCCGGCGTATGTGGGCGGTGCTGCTGGAATACGCGCTGAGCCTGGCCTGGGCGTACACCATGCTGCTCATCATCGTGCTG
TGGCTGCTCGGCAAGTTCATTGCGCTGCCGCCGGCCTTGTATGTCGACACCATCCTGCCGCGCTGGCATGGCCTGGTGCT
GGCCGTGGTCTGCCTGCTGCAGTTCGCCACCAGCCTGATGATCGAACGCCGCTACGAAAAAGGCCTGGCCCGCCAGTTCT
TCTGGGTGATCTGGTACCCGGCCGCGTTCTGGATGATCGGCATGCTCACCGCCGTCATCGCCTTCCCACGTGCCCTGCTC
GCGCGCCGCAACAAGCGCGCTCGCTGGAAAAGCCCCGACCGAGGAATCCAATGA

Upstream 100 bases:

>100_bases
GGCGTATTACCCCGACGATTTCATCGGTGGTCATCCGTTTCTGCCCGAAGCGCGCGAAGCCATCTCGGCTCGCCAATTCC
CCTATCTCGAGCGATGACCG

Downstream 100 bases:

>100_bases
CCCCACCCATCATCAACCTGCCGCAACGCCTCGGCCGCTCGCGCCGCCTCGCCTACGGCGCCGCCACCGCCGGCGCATGG
ATGGTCTACTTCTATCTGTG

Product: N-glycosyltransferase

Products: NA

Alternate protein names: PGA synthase; Poly-beta-1,6-GlcNAc synthase; Biofilm PGA synthesis protein PgaC; N-acetylglucosaminyltransferase PgaC [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTTSLLLAALFNFAFYYPIIMAFFWMIGGIYYYLRRERGTHRPSKPPPMASEPFVSILMPCYNEAKHVAETIAAMSAQQY
ADFEIIAINDGSTDRTAEVLDDLTHHHPRLRVVHLEQNHGKANALRVGTLAARSDYLVCVDADAILDPNATRWMVGHLIA
GPRVGGVTGNPRVRNRTTLMGRMQVGEFSAIVGLIKRAQRVYGRLFTVSGVICAFRRSALHHVGFWSDNMVTEDIDISWR
LQLDGWDIRYEPNALCWILMPETFRGLWMQRLRWARGGVEVLLSHGRRALAWRSRRMWAVLLEYALSLAWAYTMLLIIVL
WLLGKFIALPPALYVDTILPRWHGLVLAVVCLLQFATSLMIERRYEKGLARQFFWVIWYPAAFWMIGMLTAVIAFPRALL
ARRNKRARWKSPDRGIQ

Sequences:

>Translated_417_residues
MTTSLLLAALFNFAFYYPIIMAFFWMIGGIYYYLRRERGTHRPSKPPPMASEPFVSILMPCYNEAKHVAETIAAMSAQQY
ADFEIIAINDGSTDRTAEVLDDLTHHHPRLRVVHLEQNHGKANALRVGTLAARSDYLVCVDADAILDPNATRWMVGHLIA
GPRVGGVTGNPRVRNRTTLMGRMQVGEFSAIVGLIKRAQRVYGRLFTVSGVICAFRRSALHHVGFWSDNMVTEDIDISWR
LQLDGWDIRYEPNALCWILMPETFRGLWMQRLRWARGGVEVLLSHGRRALAWRSRRMWAVLLEYALSLAWAYTMLLIIVL
WLLGKFIALPPALYVDTILPRWHGLVLAVVCLLQFATSLMIERRYEKGLARQFFWVIWYPAAFWMIGMLTAVIAFPRALL
ARRNKRARWKSPDRGIQ
>Mature_416_residues
TTSLLLAALFNFAFYYPIIMAFFWMIGGIYYYLRRERGTHRPSKPPPMASEPFVSILMPCYNEAKHVAETIAAMSAQQYA
DFEIIAINDGSTDRTAEVLDDLTHHHPRLRVVHLEQNHGKANALRVGTLAARSDYLVCVDADAILDPNATRWMVGHLIAG
PRVGGVTGNPRVRNRTTLMGRMQVGEFSAIVGLIKRAQRVYGRLFTVSGVICAFRRSALHHVGFWSDNMVTEDIDISWRL
QLDGWDIRYEPNALCWILMPETFRGLWMQRLRWARGGVEVLLSHGRRALAWRSRRMWAVLLEYALSLAWAYTMLLIIVLW
LLGKFIALPPALYVDTILPRWHGLVLAVVCLLQFATSLMIERRYEKGLARQFFWVIWYPAAFWMIGMLTAVIAFPRALLA
RRNKRARWKSPDRGIQ

Specific function: Probable N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N- acetylglucosamine to produce the linear homopolymer poly-beta-1,6- N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide [H]

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787259, Length=412, Percent_Identity=51.2135922330097, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI1786560, Length=210, Percent_Identity=30, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: NA

Molecular weight: Translated: 47877; Mature: 47746

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSLLLAALFNFAFYYPIIMAFFWMIGGIYYYLRRERGTHRPSKPPPMASEPFVSILMP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
CYNEAKHVAETIAAMSAQQYADFEIIAINDGSTDRTAEVLDDLTHHHPRLRVVHLEQNHG
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCC
KANALRVGTLAARSDYLVCVDADAILDPNATRWMVGHLIAGPRVGGVTGNPRVRNRTTLM
CCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHE
GRMQVGEFSAIVGLIKRAQRVYGRLFTVSGVICAFRRSALHHVGFWSDNMVTEDIDISWR
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEE
LQLDGWDIRYEPNALCWILMPETFRGLWMQRLRWARGGVEVLLSHGRRALAWRSRRMWAV
EEECCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHH
LLEYALSLAWAYTMLLIIVLWLLGKFIALPPALYVDTILPRWHGLVLAVVCLLQFATSLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IERRYEKGLARQFFWVIWYPAAFWMIGMLTAVIAFPRALLARRNKRARWKSPDRGIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTSLLLAALFNFAFYYPIIMAFFWMIGGIYYYLRRERGTHRPSKPPPMASEPFVSILMP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
CYNEAKHVAETIAAMSAQQYADFEIIAINDGSTDRTAEVLDDLTHHHPRLRVVHLEQNHG
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCC
KANALRVGTLAARSDYLVCVDADAILDPNATRWMVGHLIAGPRVGGVTGNPRVRNRTTLM
CCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHE
GRMQVGEFSAIVGLIKRAQRVYGRLFTVSGVICAFRRSALHHVGFWSDNMVTEDIDISWR
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEE
LQLDGWDIRYEPNALCWILMPETFRGLWMQRLRWARGGVEVLLSHGRRALAWRSRRMWAV
EEECCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHH
LLEYALSLAWAYTMLLIIVLWLLGKFIALPPALYVDTILPRWHGLVLAVVCLLQFATSLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IERRYEKGLARQFFWVIWYPAAFWMIGMLTAVIAFPRALLARRNKRARWKSPDRGIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]