Click here to switch to the map view.

The map label for this gene is hmsF [H]

Identifier: 21242556

GI number: 21242556

Start: 2085235

End: 2087133

Strand: Reverse

Name: hmsF [H]

Synonym: XAC1812

Alternate gene names: 21242556

Gene position: 2087133-2085235 (Counterclockwise)

Preceding gene: 21242557

Following gene: 21242555

Centisome position: 40.33

GC content: 64.14

Gene sequence:

>1899_bases
ATGGGGAGGTACGCCGTGATCCGCCTGCCGCTGCTGCTGGTCGCATTGTTGCTGATGACGTTTGCCTCGTCGGCGCAGGC
GGGCCTGCTCGTGCTCAGCTACCACGATATTCGCGACGACGTCGCCGCCAAGGGCGACCCCGATCGCTATGCGGTGTCCA
CCAGCAATTTCGCCGCGCATCTGGACTGGCTGCGCTCGCATGCGTACCACCCGGTCAGCGTGCAACAGGTGCTCGATGCA
CGTGCCGGCAAGCGTGACCTGCCCTCGCGGCCGGTGCTGCTGACCTTCGACGATGGCTTGCGCAGTGTCTATACACGGGT
GTTCCCGTTGCTGCAGGCCTACGGCTATCCGGCGCTGGTCGCACCGGTGACCAGTTGGGTGGAACTGCCGGCTGGTCAGG
TCGTGCCCTATGGCCCGCGCGATTTCACCCGCGACGATTTCGTCACCTGGGCACAGTTGCGCGAGATGCAGGACAGCGGC
CTGGTCGAAATCGGGTCGCACAGCGATGACCTGCATAAAGGTATCCCGGGCAATCCGTTCGGCAATGAAACCCCGGCAGC
GGTCACGCGGCGCTGGGATGTCGGCAACGGGTACGAAAGCGAAGCGCATTATCGTCAGCGGATCGAGACCGATCTACGCC
ATAGTCGCGACGCAATGGTGGCGCATCTGGGCAAACCGCCGCGCGCCATGGTGTGGCCTTACGCTGCCTACAACCGCGCC
AGCAACGAGATCGCCGCGCGCCTGGGCATGACGCTTAGCTTCGACCTGGAAGGCCGCTCGCACGAGGCCGATATCGGCCA
GCAGGGTCGCGACCGTGTAGATGGTCAATCGTTGGCCAGCCTGGGCCGCCTGCTGCTGTTCAACAATCCCGACGTACGCG
ATCTCGCTGGCGAACTGCGGCGTGATCTGTCGCGTGACGGCGTGCGTGCGATCCAGGTCGATCTGGATTATGTCTACGAC
CCGGACCCGGCACAGCTGGAGCGCAACCTCGATGTGCTGGTACAGCGCGTCAAGGACATCGGCCCCAGCCATGTGTTCTT
GCAAGCCTTTGCCGACCCGGATGGGGATGGCGCTGCAGATGCGCTGTATTTCCCCAACCGCCATCTCCCGATGCGCGCGG
ATCTGTTCGGGCGTGTCGCCTGGCAGCTGCGCACGCGTGCCGGCGTACGTGTCTTCGCCTGGTTGCCGGTGCTCGGCTTC
CATCTGCCCGACGCGCAGCAACAAGCCGCATTGCAGATTCATGGTAACGACCCCAAGGATGTGCCGCGCCTGGATCCAGG
CAACCCGCGCACCCGCCAGCTGGTGGCAGACATCTACGAAGACCTCGCGGCCAATACCTACTTCGAAGGTCTGTTGTTCC
ATGACGATGCCTACCTGCGCGACGACGAAATACCGGCCTACGGCAATGGCGACCCGGCCAAGCGCACGCAGCAACTGATC
GGCTTCACCCAGGAACTGAAAGCCGCCGCCGAACGCTGGCGGCCGAAGCTGGTGACGGTGCGCAATCTGTTCGCACAGCC
GGTGCTGGAACCGCACAGCGAGGCCTGGTTCGCGCAGCGTCTGGAGGCCTTTGCCAGCGCGTACGACTACACCGCGCTGA
TGGCGATGCCGTACATGGAGCAAGCCAACGACGCGAATGCCTGGCTCACGCAGCTGGCCACACGCGTCGGCCAACAGCCG
CGCGGTTTCGACAAGACCATCTTCGAACTGCAGACGTTCGACTGGCGCAGCGGCAAACCGCTGCCCGACGGAGTGTTGCT
CGCGCACAGCAAGCTGCTGCTGGCAGCCGGCGTGCGTCATCTGGCGTATTACCCCGACGATTTCATCGGTGGTCATCCGT
TTCTGCCCGAAGCGCGCGAAGCCATCTCGGCTCGCCAATTCCCCTATCTCGAGCGATGA

Upstream 100 bases:

>100_bases
CGCTGGGCGATGGCAGCGCATTGAGCTACGGCGTGAGTTGGTCGCGCCCGGTCTACGACGGCCAGCGCGAACAACAACTT
GGATTGGACCTTGATTTCCG

Downstream 100 bases:

>100_bases
CCGATGACGACCAGCCTCCTACTGGCCGCCCTGTTCAACTTTGCGTTTTATTACCCGATCATCATGGCGTTCTTCTGGAT
GATCGGCGGCATCTACTACT

Product: HmsF protein

Products: NA

Alternate protein names: PGA N-deacetylase; Poly-beta-1,6-GlcNAc N-deacetylase [H]

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MGRYAVIRLPLLLVALLLMTFASSAQAGLLVLSYHDIRDDVAAKGDPDRYAVSTSNFAAHLDWLRSHAYHPVSVQQVLDA
RAGKRDLPSRPVLLTFDDGLRSVYTRVFPLLQAYGYPALVAPVTSWVELPAGQVVPYGPRDFTRDDFVTWAQLREMQDSG
LVEIGSHSDDLHKGIPGNPFGNETPAAVTRRWDVGNGYESEAHYRQRIETDLRHSRDAMVAHLGKPPRAMVWPYAAYNRA
SNEIAARLGMTLSFDLEGRSHEADIGQQGRDRVDGQSLASLGRLLLFNNPDVRDLAGELRRDLSRDGVRAIQVDLDYVYD
PDPAQLERNLDVLVQRVKDIGPSHVFLQAFADPDGDGAADALYFPNRHLPMRADLFGRVAWQLRTRAGVRVFAWLPVLGF
HLPDAQQQAALQIHGNDPKDVPRLDPGNPRTRQLVADIYEDLAANTYFEGLLFHDDAYLRDDEIPAYGNGDPAKRTQQLI
GFTQELKAAAERWRPKLVTVRNLFAQPVLEPHSEAWFAQRLEAFASAYDYTALMAMPYMEQANDANAWLTQLATRVGQQP
RGFDKTIFELQTFDWRSGKPLPDGVLLAHSKLLLAAGVRHLAYYPDDFIGGHPFLPEAREAISARQFPYLER

Sequences:

>Translated_632_residues
MGRYAVIRLPLLLVALLLMTFASSAQAGLLVLSYHDIRDDVAAKGDPDRYAVSTSNFAAHLDWLRSHAYHPVSVQQVLDA
RAGKRDLPSRPVLLTFDDGLRSVYTRVFPLLQAYGYPALVAPVTSWVELPAGQVVPYGPRDFTRDDFVTWAQLREMQDSG
LVEIGSHSDDLHKGIPGNPFGNETPAAVTRRWDVGNGYESEAHYRQRIETDLRHSRDAMVAHLGKPPRAMVWPYAAYNRA
SNEIAARLGMTLSFDLEGRSHEADIGQQGRDRVDGQSLASLGRLLLFNNPDVRDLAGELRRDLSRDGVRAIQVDLDYVYD
PDPAQLERNLDVLVQRVKDIGPSHVFLQAFADPDGDGAADALYFPNRHLPMRADLFGRVAWQLRTRAGVRVFAWLPVLGF
HLPDAQQQAALQIHGNDPKDVPRLDPGNPRTRQLVADIYEDLAANTYFEGLLFHDDAYLRDDEIPAYGNGDPAKRTQQLI
GFTQELKAAAERWRPKLVTVRNLFAQPVLEPHSEAWFAQRLEAFASAYDYTALMAMPYMEQANDANAWLTQLATRVGQQP
RGFDKTIFELQTFDWRSGKPLPDGVLLAHSKLLLAAGVRHLAYYPDDFIGGHPFLPEAREAISARQFPYLER
>Mature_631_residues
GRYAVIRLPLLLVALLLMTFASSAQAGLLVLSYHDIRDDVAAKGDPDRYAVSTSNFAAHLDWLRSHAYHPVSVQQVLDAR
AGKRDLPSRPVLLTFDDGLRSVYTRVFPLLQAYGYPALVAPVTSWVELPAGQVVPYGPRDFTRDDFVTWAQLREMQDSGL
VEIGSHSDDLHKGIPGNPFGNETPAAVTRRWDVGNGYESEAHYRQRIETDLRHSRDAMVAHLGKPPRAMVWPYAAYNRAS
NEIAARLGMTLSFDLEGRSHEADIGQQGRDRVDGQSLASLGRLLLFNNPDVRDLAGELRRDLSRDGVRAIQVDLDYVYDP
DPAQLERNLDVLVQRVKDIGPSHVFLQAFADPDGDGAADALYFPNRHLPMRADLFGRVAWQLRTRAGVRVFAWLPVLGFH
LPDAQQQAALQIHGNDPKDVPRLDPGNPRTRQLVADIYEDLAANTYFEGLLFHDDAYLRDDEIPAYGNGDPAKRTQQLIG
FTQELKAAAERWRPKLVTVRNLFAQPVLEPHSEAWFAQRLEAFASAYDYTALMAMPYMEQANDANAWLTQLATRVGQQPR
GFDKTIFELQTFDWRSGKPLPDGVLLAHSKLLLAAGVRHLAYYPDDFIGGHPFLPEAREAISARQFPYLER

Specific function: Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl- D-glucosamine (PGA), a biofilm adhesin polysaccharide. N- deacetylation promotes PGA export through the PgaA porin [H]

COG id: COG0726

COG function: function code G; Predicted xylanase/chitin deacetylase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide deacetylase family [H]

Homologues:

Organism=Escherichia coli, GI1787260, Length=642, Percent_Identity=39.0965732087227, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1786322, Length=147, Percent_Identity=31.9727891156463, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011330
- InterPro:   IPR002509 [H]

Pfam domain/function: PF01522 Polysacc_deac_1 [H]

EC number: NA

Molecular weight: Translated: 70904; Mature: 70773

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRYAVIRLPLLLVALLLMTFASSAQAGLLVLSYHDIRDDVAAKGDPDRYAVSTSNFAAH
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHCCCCCCCCEEEECCHHHHH
LDWLRSHAYHPVSVQQVLDARAGKRDLPSRPVLLTFDDGLRSVYTRVFPLLQAYGYPALV
HHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCHHH
APVTSWVELPAGQVVPYGPRDFTRDDFVTWAQLREMQDSGLVEIGSHSDDLHKGIPGNPF
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCHHHCCCCCCCC
GNETPAAVTRRWDVGNGYESEAHYRQRIETDLRHSRDAMVAHLGKPPRAMVWPYAAYNRA
CCCCCHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHCC
SNEIAARLGMTLSFDLEGRSHEADIGQQGRDRVDGQSLASLGRLLLFNNPDVRDLAGELR
HHHHHHHHCCEEEEECCCCCCCCCCCCCCHHCCCHHHHHHHHHEEEECCCCHHHHHHHHH
RDLSRDGVRAIQVDLDYVYDPDPAQLERNLDVLVQRVKDIGPSHVFLQAFADPDGDGAAD
HHHHHCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCC
ALYFPNRHLPMRADLFGRVAWQLRTRAGVRVFAWLPVLGFHLPDAQQQAALQIHGNDPKD
EEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCCCCCEEEEECCCCCC
VPRLDPGNPRTRQLVADIYEDLAANTYFEGLLFHDDAYLRDDEIPAYGNGDPAKRTQQLI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCEECCCCCCCCCCCCHHHHHHHHH
GFTQELKAAAERWRPKLVTVRNLFAQPVLEPHSEAWFAQRLEAFASAYDYTALMAMPYME
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QANDANAWLTQLATRVGQQPRGFDKTIFELQTFDWRSGKPLPDGVLLAHSKLLLAAGVRH
HCCCHHHHHHHHHHHHCCCCCCCCHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
LAYYPDDFIGGHPFLPEAREAISARQFPYLER
HHCCCCHHCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GRYAVIRLPLLLVALLLMTFASSAQAGLLVLSYHDIRDDVAAKGDPDRYAVSTSNFAAH
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHCCCCCCCCEEEECCHHHHH
LDWLRSHAYHPVSVQQVLDARAGKRDLPSRPVLLTFDDGLRSVYTRVFPLLQAYGYPALV
HHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCHHH
APVTSWVELPAGQVVPYGPRDFTRDDFVTWAQLREMQDSGLVEIGSHSDDLHKGIPGNPF
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCHHHCCCCCCCC
GNETPAAVTRRWDVGNGYESEAHYRQRIETDLRHSRDAMVAHLGKPPRAMVWPYAAYNRA
CCCCCHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHCC
SNEIAARLGMTLSFDLEGRSHEADIGQQGRDRVDGQSLASLGRLLLFNNPDVRDLAGELR
HHHHHHHHCCEEEEECCCCCCCCCCCCCCHHCCCHHHHHHHHHEEEECCCCHHHHHHHHH
RDLSRDGVRAIQVDLDYVYDPDPAQLERNLDVLVQRVKDIGPSHVFLQAFADPDGDGAAD
HHHHHCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCC
ALYFPNRHLPMRADLFGRVAWQLRTRAGVRVFAWLPVLGFHLPDAQQQAALQIHGNDPKD
EEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCCCCCEEEEECCCCCC
VPRLDPGNPRTRQLVADIYEDLAANTYFEGLLFHDDAYLRDDEIPAYGNGDPAKRTQQLI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCEECCCCCCCCCCCCHHHHHHHHH
GFTQELKAAAERWRPKLVTVRNLFAQPVLEPHSEAWFAQRLEAFASAYDYTALMAMPYME
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QANDANAWLTQLATRVGQQPRGFDKTIFELQTFDWRSGKPLPDGVLLAHSKLLLAAGVRH
HCCCHHHHHHHHHHHHCCCCCCCCHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
LAYYPDDFIGGHPFLPEAREAISARQFPYLER
HHCCCCHHCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]