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The map label for this gene is panD

Identifier: 21242532

GI number: 21242532

Start: 2056154

End: 2056534

Strand: Direct

Name: panD

Synonym: XAC1787

Alternate gene names: 21242532

Gene position: 2056154-2056534 (Clockwise)

Preceding gene: 21242531

Following gene: 21242533

Centisome position: 39.73

GC content: 61.68

Gene sequence:

>381_bases
ATGCATCTGTCCCTGCTGAAAGCCAAGATCCACCGCGCCACCGTCACCCACTCCGAGCTCAACTACGAAGGCTCGATCGC
CATCGACGGCCTGCTGCTGGAAGCGACCGGCATCCGCGAGTTCGAACAGGTCCATATCTGGGACGTCACCAACGGTGCGC
GTTTCAGCACCTATGCCATCCGCGCCGAAGACGGCAGCGGCATCATGTCGCTCAACGGTGGCGCGGCGCGTCACGTGCAG
GTGGGCGATCTGATCATCGTGGCGGCGTTCGCCAGCATGAGCGAAGACGAAGCCAAGACCTTCAAGCCCAATCTGGTATA
TGTGAACGCGCACAACGCGATCTCCCACACCAACCACAGCATCCCCACCCAGGCCGCATGA

Upstream 100 bases:

>100_bases
GCGCAGGCCTGAAGCCCTCACCACCGGCCGCAGCGCAAACCGGTGGGGACGGGCGCTTTCCGCTAAAATGCCGGCTTTCC
TTTTGTCGTTGCCTGCGTCC

Downstream 100 bases:

>100_bases
CACAGACCAACGGATTCGACGCGCTTCACGCCCACGCCCAGCGCCTGCGCGGCGCTGCCATCCCCGCATTGCTTGCCGCC
GAGCCGGAACGGCCGACGCA

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MHLSLLKAKIHRATVTHSELNYEGSIAIDGLLLEATGIREFEQVHIWDVTNGARFSTYAIRAEDGSGIMSLNGGAARHVQ
VGDLIIVAAFASMSEDEAKTFKPNLVYVNAHNAISHTNHSIPTQAA

Sequences:

>Translated_126_residues
MHLSLLKAKIHRATVTHSELNYEGSIAIDGLLLEATGIREFEQVHIWDVTNGARFSTYAIRAEDGSGIMSLNGGAARHVQ
VGDLIIVAAFASMSEDEAKTFKPNLVYVNAHNAISHTNHSIPTQAA
>Mature_126_residues
MHLSLLKAKIHRATVTHSELNYEGSIAIDGLLLEATGIREFEQVHIWDVTNGARFSTYAIRAEDGSGIMSLNGGAARHVQ
VGDLIIVAAFASMSEDEAKTFKPNLVYVNAHNAISHTNHSIPTQAA

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=126, Percent_Identity=50.7936507936508, Blast_Score=138, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND_XANAC (Q8PLK9)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642114.1
- ProteinModelPortal:   Q8PLK9
- SMR:   Q8PLK9
- GeneID:   1155858
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1787
- NMPDR:   fig|190486.1.peg.1758
- HOGENOM:   HBG302821
- OMA:   LYSKIHR
- ProtClustDB:   PRK05449
- BioCyc:   XAXO190486:XAC1787-MONOMER
- BRENDA:   4.1.1.11
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 13624; Mature: 13624

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 25-25 ACT_SITE 58-58 BINDING 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLSLLKAKIHRATVTHSELNYEGSIAIDGLLLEATGIREFEQVHIWDVTNGARFSTYAI
CCHHHHHHHHHHEEEECCCCCCCCCEEEEEEEEEECCCCCEEEEEEEECCCCCEEEEEEE
RAEDGSGIMSLNGGAARHVQVGDLIIVAAFASMSEDEAKTFKPNLVYVNAHNAISHTNHS
EECCCCEEEEECCCCEEEEEECCEEEEEEECCCCCCCHHCCCCCEEEEECCCCCCCCCCC
IPTQAA
CCCCCC
>Mature Secondary Structure
MHLSLLKAKIHRATVTHSELNYEGSIAIDGLLLEATGIREFEQVHIWDVTNGARFSTYAI
CCHHHHHHHHHHEEEECCCCCCCCCEEEEEEEEEECCCCCEEEEEEEECCCCCEEEEEEE
RAEDGSGIMSLNGGAARHVQVGDLIIVAAFASMSEDEAKTFKPNLVYVNAHNAISHTNHS
EECCCCEEEEECCCCEEEEEECCEEEEEEECCCCCCCHHCCCCCEEEEECCCCCCCCCCC
IPTQAA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217