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The map label for this gene is panC [H]

Identifier: 21242531

GI number: 21242531

Start: 2055145

End: 2055987

Strand: Direct

Name: panC [H]

Synonym: XAC1786

Alternate gene names: 21242531

Gene position: 2055145-2055987 (Clockwise)

Preceding gene: 21242530

Following gene: 21242532

Centisome position: 39.71

GC content: 66.31

Gene sequence:

>843_bases
ATGATCCAGACCCTGACCGATCTTTCCGCACTGCGCGCCCTGGTCAATGGCTGGAAGCGCGAGGGCTTGCGTGTGGCGCT
GGTGCCTACCATGGGCAACCTGCACGCCGGGCATTATTCGTTGGTGATGCTGGCGCGCCAGTACGCCGACCGCGTAGTGT
CCAGCGTGTTCGTCAACCCGACCCAGTTCGGCCCGAATGAAGATTTTGCGCGCTACCCGCGCACGCCCGAGGCCGACCTG
CGCGGCCTGGAAGACGCCGGTTGCGATGCGCTGTGGCTGCCGGACGTGGACACCATGTACCCGCTCGGCACCGCGCTGGC
CACACCGATCCACGCGCCCGGCGTCAGTGATGTGCTGGAAGGCGAATGCCGGCCCGGGCATTTCGATGGCGTGTGCACCG
TGGTGGCGCGATTGTTCAACCAGGTGCAGCCGGACGTGGCCGCCTTCGGCAAGAAGGATTACCAGCAGTTGGCGGTGATC
CGGCAGATGGTGGCCGACCTGGCGTTTCCGATCGAAATTTTGGGCGGCAGCATCGTGCGCGAGGCCGATGGCCTGGCGAT
GAGCTCGCGCAACCAGTATCTGTCGGCGGAAGATCGCCCGATCTCGAGCACGATCCGCAAGGTGCTGCTGCAGATGCGCG
ACAGCTATGCCGCCGGCACGCCGCGTGCGCAGGTGGAAGATGCGGCCAGCCACACGCTGGAACAGGCCGGTTTCCGGGTC
GATTACGCGGTGGTGCGGCTGCCTGATCTCAGCGAGCCGGGCGACAGCCACGCCGGCGCGCGCGTGGCCTTGATCGCGGC
CCGGTTGGGCAACACGCGCTTGATCGACAACCTGGAGTTCTGA

Upstream 100 bases:

>100_bases
ATTTCCTGGCCGAAGGCGGCTCGGTTGCCGGCGCGGTGCGCGCCTATGCACAGGCGGTGCGCGACGGCAGTTTTCCCGAT
GCAGAGCACGCGTACGCCGC

Downstream 100 bases:

>100_bases
GCAGGCCGACGCGCCGTCGGAGCCGTCCGGCAGCGCCAGCGAACGGGGCGCGCGTTTGCGCGCGCTGCGCAGGCCTGAAG
CCCTCACCACCGGCCGCAGC

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MIQTLTDLSALRALVNGWKREGLRVALVPTMGNLHAGHYSLVMLARQYADRVVSSVFVNPTQFGPNEDFARYPRTPEADL
RGLEDAGCDALWLPDVDTMYPLGTALATPIHAPGVSDVLEGECRPGHFDGVCTVVARLFNQVQPDVAAFGKKDYQQLAVI
RQMVADLAFPIEILGGSIVREADGLAMSSRNQYLSAEDRPISSTIRKVLLQMRDSYAAGTPRAQVEDAASHTLEQAGFRV
DYAVVRLPDLSEPGDSHAGARVALIAARLGNTRLIDNLEF

Sequences:

>Translated_280_residues
MIQTLTDLSALRALVNGWKREGLRVALVPTMGNLHAGHYSLVMLARQYADRVVSSVFVNPTQFGPNEDFARYPRTPEADL
RGLEDAGCDALWLPDVDTMYPLGTALATPIHAPGVSDVLEGECRPGHFDGVCTVVARLFNQVQPDVAAFGKKDYQQLAVI
RQMVADLAFPIEILGGSIVREADGLAMSSRNQYLSAEDRPISSTIRKVLLQMRDSYAAGTPRAQVEDAASHTLEQAGFRV
DYAVVRLPDLSEPGDSHAGARVALIAARLGNTRLIDNLEF
>Mature_280_residues
MIQTLTDLSALRALVNGWKREGLRVALVPTMGNLHAGHYSLVMLARQYADRVVSSVFVNPTQFGPNEDFARYPRTPEADL
RGLEDAGCDALWLPDVDTMYPLGTALATPIHAPGVSDVLEGECRPGHFDGVCTVVARLFNQVQPDVAAFGKKDYQQLAVI
RQMVADLAFPIEILGGSIVREADGLAMSSRNQYLSAEDRPISSTIRKVLLQMRDSYAAGTPRAQVEDAASHTLEQAGFRV
DYAVVRLPDLSEPGDSHAGARVALIAARLGNTRLIDNLEF

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=272, Percent_Identity=50.3676470588235, Blast_Score=246, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6322046, Length=248, Percent_Identity=37.0967741935484, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 30473; Mature: 30473

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQTLTDLSALRALVNGWKREGLRVALVPTMGNLHAGHYSLVMLARQYADRVVSSVFVNP
CCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
TQFGPNEDFARYPRTPEADLRGLEDAGCDALWLPDVDTMYPLGTALATPIHAPGVSDVLE
CCCCCCCCHHHCCCCCCHHHCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCHHHHHC
GECRPGHFDGVCTVVARLFNQVQPDVAAFGKKDYQQLAVIRQMVADLAFPIEILGGSIVR
CCCCCCCCHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
EADGLAMSSRNQYLSAEDRPISSTIRKVLLQMRDSYAAGTPRAQVEDAASHTLEQAGFRV
HHCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEE
DYAVVRLPDLSEPGDSHAGARVALIAARLGNTRLIDNLEF
EEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIQTLTDLSALRALVNGWKREGLRVALVPTMGNLHAGHYSLVMLARQYADRVVSSVFVNP
CCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
TQFGPNEDFARYPRTPEADLRGLEDAGCDALWLPDVDTMYPLGTALATPIHAPGVSDVLE
CCCCCCCCHHHCCCCCCHHHCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCHHHHHC
GECRPGHFDGVCTVVARLFNQVQPDVAAFGKKDYQQLAVIRQMVADLAFPIEILGGSIVR
CCCCCCCCHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
EADGLAMSSRNQYLSAEDRPISSTIRKVLLQMRDSYAAGTPRAQVEDAASHTLEQAGFRV
HHCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEE
DYAVVRLPDLSEPGDSHAGARVALIAARLGNTRLIDNLEF
EEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA