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The map label for this gene is fucP [H]

Identifier: 21242307

GI number: 21242307

Start: 1796652

End: 1797962

Strand: Direct

Name: fucP [H]

Synonym: XAC1556

Alternate gene names: 21242307

Gene position: 1796652-1797962 (Clockwise)

Preceding gene: 21242306

Following gene: 21242308

Centisome position: 34.71

GC content: 62.09

Gene sequence:

>1311_bases
ATGGTTTCCCTTTCCACGCAATCCTCCGTGCCCAGCGGCAACAAGGCGCCCGTCAACAACGGCGTCGCGTTGTCGGTGGT
CACCACGATCTTTTTCATGTGGGGCTTTCTGACCTGCCTCAACGACATCCTGATTCCGCATCTGAAGGCGGTGTTCGAGC
TCAACTTCGCGCAGGCGATGCTGGTGCAGTTCACCTTCTTCGGTGCCTATTTCCTGATGTCGCTGCCGGCCGGTTGGCTG
GTGAACCGGTTGGGCTATAAGCAGGGTATCGTGGCCGGCTTGGCGGTGGCGGCGGTCGGCGCGCTGGGCTTCTGGCCGGC
GGCGGAATTGCGCGTGTACAGCGCATTTCTCGGCGCGTTGTTCGTATTGGCCACTGGCATCACCATCTTGCAGGTGGCGG
CCAATCCCTACGTCGCCTTGCTGGGGCCAGAGCGTAGCGCCTCCAGTCGCTTGACCCTGGCCCAGGCACTGAATTCGCTC
GGCACTGCAATCGCGCCACTGTTGGGCGGCTGGTTGATCCTGTCCAACACGGTAATGAGCGGCGACCAACTGAAGGCCCT
GCCGGAAGCTGAGCAACTGGCTTATCGCGTGCAGGAAGCGCAGGCCGTGCAAGGCCCGTACATCGGGCTGGGCATCGTGC
TGTTCCTGTTGGCGATCTTCGTGTTTTTGTTCCGTCTGCCGGCTCTGACCGACGCCAGCGCACAGAAAGACGACAGCACG
CATTCCTTGCTCGATGCCTTGCAACACCCGCATGTGCGCTTCGGTGTGTTGGCGATCTTTTTCTACGTTGGCGCCGAAGT
GGCGATCGGCAGCCTGATGGTCAATTACTTCTCGCTGCCGCAGATCGGTGGGTTCACCGAGCGCGAGGCAACCAAGTATG
TGTCGGCCTACTGGACGCTGGCGATGATCGGCCGTTTCATCGGCTCGGCGCTGCTGGCCAAGCTGTCGCCGCGCGTGTTG
TTGTCGGTGTTCGCTGCAATCAACGCGGTGTTGCTGGGCCTGACCATGACCAGCGGCGGCATGTTGGCGGTGTACGCGCT
GGTGGCGATCGGCCTGTTCAATTCGATCATGTTCCCGACCATCTTCACCCTGGGCATCGAGCGGCTTGGTCCGCTGACCG
GGCGCGCGTCGAGCCTGCTGATCATGGCCATTGTCGGCGGCGCAATCGTGCCGTATCTGCAAGGGTTGCTCGCCGACAGC
ATCGGCCTGCATGAGTCGTTCGTGCTGCCGTTGCTGTGCTACCTGTACATCGTGTTCTACGGTATCTGGGGCTCGCGGTT
GCGCGGCGCACTGGCGGAGGCACGCGCATGA

Upstream 100 bases:

>100_bases
AGCGCCTGCGGACCCACAACGCGAATGTCACCACCTCCCCCAAGCGGTCCATCCGCCCATTCCCCCACCAAGGCCTCAGG
CCGCTGACCAGGCAATCCCT

Downstream 100 bases:

>100_bases
GTGCGAGCAAGCATCAGGTGGTGTGTTTCGGCGAAGCGCTGATCGACATGCTGGCGTTGCCGCAGGCCCGCCCGGACGAG
GCGCGCACCTTCGCGCAATA

Product: glucose-galactose transporter

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MVSLSTQSSVPSGNKAPVNNGVALSVVTTIFFMWGFLTCLNDILIPHLKAVFELNFAQAMLVQFTFFGAYFLMSLPAGWL
VNRLGYKQGIVAGLAVAAVGALGFWPAAELRVYSAFLGALFVLATGITILQVAANPYVALLGPERSASSRLTLAQALNSL
GTAIAPLLGGWLILSNTVMSGDQLKALPEAEQLAYRVQEAQAVQGPYIGLGIVLFLLAIFVFLFRLPALTDASAQKDDST
HSLLDALQHPHVRFGVLAIFFYVGAEVAIGSLMVNYFSLPQIGGFTEREATKYVSAYWTLAMIGRFIGSALLAKLSPRVL
LSVFAAINAVLLGLTMTSGGMLAVYALVAIGLFNSIMFPTIFTLGIERLGPLTGRASSLLIMAIVGGAIVPYLQGLLADS
IGLHESFVLPLLCYLYIVFYGIWGSRLRGALAEARA

Sequences:

>Translated_436_residues
MVSLSTQSSVPSGNKAPVNNGVALSVVTTIFFMWGFLTCLNDILIPHLKAVFELNFAQAMLVQFTFFGAYFLMSLPAGWL
VNRLGYKQGIVAGLAVAAVGALGFWPAAELRVYSAFLGALFVLATGITILQVAANPYVALLGPERSASSRLTLAQALNSL
GTAIAPLLGGWLILSNTVMSGDQLKALPEAEQLAYRVQEAQAVQGPYIGLGIVLFLLAIFVFLFRLPALTDASAQKDDST
HSLLDALQHPHVRFGVLAIFFYVGAEVAIGSLMVNYFSLPQIGGFTEREATKYVSAYWTLAMIGRFIGSALLAKLSPRVL
LSVFAAINAVLLGLTMTSGGMLAVYALVAIGLFNSIMFPTIFTLGIERLGPLTGRASSLLIMAIVGGAIVPYLQGLLADS
IGLHESFVLPLLCYLYIVFYGIWGSRLRGALAEARA
>Mature_436_residues
MVSLSTQSSVPSGNKAPVNNGVALSVVTTIFFMWGFLTCLNDILIPHLKAVFELNFAQAMLVQFTFFGAYFLMSLPAGWL
VNRLGYKQGIVAGLAVAAVGALGFWPAAELRVYSAFLGALFVLATGITILQVAANPYVALLGPERSASSRLTLAQALNSL
GTAIAPLLGGWLILSNTVMSGDQLKALPEAEQLAYRVQEAQAVQGPYIGLGIVLFLLAIFVFLFRLPALTDASAQKDDST
HSLLDALQHPHVRFGVLAIFFYVGAEVAIGSLMVNYFSLPQIGGFTEREATKYVSAYWTLAMIGRFIGSALLAKLSPRVL
LSVFAAINAVLLGLTMTSGGMLAVYALVAIGLFNSIMFPTIFTLGIERLGPLTGRASSLLIMAIVGGAIVPYLQGLLADS
IGLHESFVLPLLCYLYIVFYGIWGSRLRGALAEARA

Specific function: Intake of glucose and galactose (Potential) [H]

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=432, Percent_Identity=36.3425925925926, Blast_Score=251, Evalue=6e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005964
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46471; Mature: 46471

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9168605 [H]