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The map label for this gene is scrK [H]

Identifier: 21242308

GI number: 21242308

Start: 1797887

End: 1798945

Strand: Direct

Name: scrK [H]

Synonym: XAC1557

Alternate gene names: 21242308

Gene position: 1797887-1798945 (Clockwise)

Preceding gene: 21242307

Following gene: 21242309

Centisome position: 34.74

GC content: 65.34

Gene sequence:

>1059_bases
GTGCTACCTGTACATCGTGTTCTACGGTATCTGGGGCTCGCGGTTGCGCGGCGCACTGGCGGAGGCACGCGCATGAGTGC
GAGCAAGCATCAGGTGGTGTGTTTCGGCGAAGCGCTGATCGACATGCTGGCGTTGCCGCAGGCCCGCCCGGACGAGGCGC
GCACCTTCGCGCAATATGCCGGCGGTGCGCCGGCCAATGTCGCCGTTGCGGTGGCGCGCCTGGGGGGCGCTGCGCATTTT
GTGGGCATGCTCGGGCGCGACATGTTCGGCGATTTCCTGCTGCAAAGCCTGCAGCAATCCGGCGTGGCGACCGACGGCAT
CGTACGCACCGATCAGGCCAAGACTGCGTTGGCGTTCGTTGCGCTGGACGACGCGGGCGAACGCAGTTTCAGTTTCTACC
GTCCACCGGCAGCGGACCTGTTGTTCCGTCCCGAGCACTTCGCTGCGGACGGGTTTACGCAGGCAGCGGTCTTGCATGTG
TGCTCCAACAGCATGACCGAGCCGGAAATTGCCCAGTGCACGCTCGACGGCATGCGCCGTGCGCGCGCCGATGGCGCCAT
CGTCAGCCTTGATCTGAATCTGCGCCCGATGCTGTGGCCGCAGGATGTCGAGCCGGCGCCGTTGCTATGGGAGGCGCTGG
CGTTGGCCGATGTGGTCAAGCTTTCGCGCGAGGAACTTGAGTATCTGGCGGGAACGCTCGATAGCGACGCCAGTGCGGTC
ACGCAAAAGCTGTGGCAGGGCAGGGCCAGTTGGTTGCTGGTCACCGATGGCGGCGGGCCGGTGCATTGGCAGACACGTAC
CGATTCAGGCCAGGTGCCGGCGTTCCAGGTGCAGGTGCGCGATAGCACCGCCGCCGGCGATGCGTTCGTCGGCGGGCTGC
TGTATCAGCTGGCGACGCGTGCTGCATCGCTGGAGCAGCTGTGCGGTGATCCCGCGGTAATCAATGAGGTGATCCGGTTT
GCTGCCGCGGTCGGCGCGCTGGCGGTGACGCGCAAGGGCGCGTTCGCGGCAATGCCGAGCATCGATGAAGTCCATTCCTT
GATCCAGGAACAATCATGA

Upstream 100 bases:

>100_bases
TGCTGATCATGGCCATTGTCGGCGGCGCAATCGTGCCGTATCTGCAAGGGTTGCTCGCCGACAGCATCGGCCTGCATGAG
TCGTTCGTGCTGCCGTTGCT

Downstream 100 bases:

>100_bases
GCCGTTTGCCTGCAACACCCGCACCCGATTTCCGTTCGGCCGACGTCTTGCGCCAGCACATCGCCGACACCATGGCGTTC
TATCATCCGCGCGCGATCGA

Product: fructokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MLPVHRVLRYLGLAVARRTGGGTRMSASKHQVVCFGEALIDMLALPQARPDEARTFAQYAGGAPANVAVAVARLGGAAHF
VGMLGRDMFGDFLLQSLQQSGVATDGIVRTDQAKTALAFVALDDAGERSFSFYRPPAADLLFRPEHFAADGFTQAAVLHV
CSNSMTEPEIAQCTLDGMRRARADGAIVSLDLNLRPMLWPQDVEPAPLLWEALALADVVKLSREELEYLAGTLDSDASAV
TQKLWQGRASWLLVTDGGGPVHWQTRTDSGQVPAFQVQVRDSTAAGDAFVGGLLYQLATRAASLEQLCGDPAVINEVIRF
AAAVGALAVTRKGAFAAMPSIDEVHSLIQEQS

Sequences:

>Translated_352_residues
MLPVHRVLRYLGLAVARRTGGGTRMSASKHQVVCFGEALIDMLALPQARPDEARTFAQYAGGAPANVAVAVARLGGAAHF
VGMLGRDMFGDFLLQSLQQSGVATDGIVRTDQAKTALAFVALDDAGERSFSFYRPPAADLLFRPEHFAADGFTQAAVLHV
CSNSMTEPEIAQCTLDGMRRARADGAIVSLDLNLRPMLWPQDVEPAPLLWEALALADVVKLSREELEYLAGTLDSDASAV
TQKLWQGRASWLLVTDGGGPVHWQTRTDSGQVPAFQVQVRDSTAAGDAFVGGLLYQLATRAASLEQLCGDPAVINEVIRF
AAAVGALAVTRKGAFAAMPSIDEVHSLIQEQS
>Mature_352_residues
MLPVHRVLRYLGLAVARRTGGGTRMSASKHQVVCFGEALIDMLALPQARPDEARTFAQYAGGAPANVAVAVARLGGAAHF
VGMLGRDMFGDFLLQSLQQSGVATDGIVRTDQAKTALAFVALDDAGERSFSFYRPPAADLLFRPEHFAADGFTQAAVLHV
CSNSMTEPEIAQCTLDGMRRARADGAIVSLDLNLRPMLWPQDVEPAPLLWEALALADVVKLSREELEYLAGTLDSDASAV
TQKLWQGRASWLLVTDGGGPVHWQTRTDSGQVPAFQVQVRDSTAAGDAFVGGLLYQLATRAASLEQLCGDPAVINEVIRF
AAAVGALAVTRKGAFAAMPSIDEVHSLIQEQS

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=275, Percent_Identity=28.3636363636364, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87082343, Length=324, Percent_Identity=31.7901234567901, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI87082281, Length=287, Percent_Identity=27.5261324041812, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790193, Length=325, Percent_Identity=28.9230769230769, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=339, Percent_Identity=28.3185840707965, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.4 [H]

Molecular weight: Translated: 37543; Mature: 37543

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVHRVLRYLGLAVARRTGGGTRMSASKHQVVCFGEALIDMLALPQARPDEARTFAQYA
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCHHHHHHHHHC
GGAPANVAVAVARLGGAAHFVGMLGRDMFGDFLLQSLQQSGVATDGIVRTDQAKTALAFV
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHEEEEE
ALDDAGERSFSFYRPPAADLLFRPEHFAADGFTQAAVLHVCSNSMTEPEIAQCTLDGMRR
EECCCCCCCCEECCCCHHHHEECCCHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ARADGAIVSLDLNLRPMLWPQDVEPAPLLWEALALADVVKLSREELEYLAGTLDSDASAV
HCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TQKLWQGRASWLLVTDGGGPVHWQTRTDSGQVPAFQVQVRDSTAAGDAFVGGLLYQLATR
HHHHHCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
AASLEQLCGDPAVINEVIRFAAAVGALAVTRKGAFAAMPSIDEVHSLIQEQS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MLPVHRVLRYLGLAVARRTGGGTRMSASKHQVVCFGEALIDMLALPQARPDEARTFAQYA
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCHHHHHHHHHC
GGAPANVAVAVARLGGAAHFVGMLGRDMFGDFLLQSLQQSGVATDGIVRTDQAKTALAFV
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHEEEEE
ALDDAGERSFSFYRPPAADLLFRPEHFAADGFTQAAVLHVCSNSMTEPEIAQCTLDGMRR
EECCCCCCCCEECCCCHHHHEECCCHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ARADGAIVSLDLNLRPMLWPQDVEPAPLLWEALALADVVKLSREELEYLAGTLDSDASAV
HCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TQKLWQGRASWLLVTDGGGPVHWQTRTDSGQVPAFQVQVRDSTAAGDAFVGGLLYQLATR
HHHHHCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
AASLEQLCGDPAVINEVIRFAAAVGALAVTRKGAFAAMPSIDEVHSLIQEQS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2174811 [H]