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The map label for this gene is trpE [H]

Identifier: 21241885

GI number: 21241885

Start: 1280141

End: 1281496

Strand: Direct

Name: trpE [H]

Synonym: XAC1130

Alternate gene names: 21241885

Gene position: 1280141-1281496 (Clockwise)

Preceding gene: 21241884

Following gene: 21241886

Centisome position: 24.73

GC content: 68.66

Gene sequence:

>1356_bases
ATGACGCTTACCCGATCACTGCACGCGGACATCGACCTGCTGGCGCTGCATCGGCTGTCACCGCAACGCTATCCGGCCCT
GCTGGAGTCCAGCGCTTCCGGCACCGAGCATGGTCGCTGGGATGTGCTGCTGCTGGCAGAGGGGCCATGCCTGCGGCTGG
ATCCGGACGGATGTACGCGCGATGGCGCTGGGCGGTTGCTGGAGGGCGGCTTTCTGGCGGCGCTGGATGCCGCCTGGCAG
GCCGAGCGCGTGCCGCACGACGCGGCAAGCCCATGGCCGTTTCGCGGCGGTTGGGCAGTGCTGCTGGATTACGAACTTGC
CGCGCAGGTCGAGCCGATTCTGCAACTGCCCACGCGCCGCGACGGCGTGCCCACCGCGCTGGCCTTGCGCGCGCCGGCAG
CGGTGCTGCGCGATCGCCTGCACGGGCGCTGTGTGGCGCTGGCAGAGCCGGGCCGCGAGGAGTTGTTGCAGCAGATCGGC
GACGACCTTGCTGCCTGCGCTGCACTGCCGCCGCTGCCTGCCTGGGCCGGGCCGCTTGCGGTGGACGAAGAGGCCCCCGA
GCGTTTTACCGGGGCAGTGGAGCGCGTGCTCGATTACCTGCGTGCCGGCGATGTCTTCCAGGCCAATATCTCGCGCGCCT
GGCACGCGGCATTCGCTGCGGTGGTCGATCCGGCCGCGTTGCATGCGCGCCTGCGTGCGGCCAATCCGGCGCCGTTTGCC
GGCCTGTTCGTTGCCGCCGGGCGTGCAGTGGCCAGTTCCTCGCCAGAGCGGCTGGTCTCGGTACAGGGCGATGTGGTGCA
GACGCGCCCGATCGCCGGCACCCGCGCGCGGTTTGCCGGGGACGACGATGCCGCACGTATCCGGGAGCTGGTCGGGCATC
CGAAGGAGCGCGCCGAGCACGTGATGCTGATCGATCTGGAGCGCAACGACCTGGGCCGCATCTGCGCGCCGGGCACCGTG
GAGGTGGACGAGTTGATGTGCGTGGAGAGCTATGCGCATGTGCATCACATCGTCAGCAACGTGCGCGGGCGTCTGCGCGC
CGGGGTAACGCCCGGTGAGGTGATTGCCGCGGTGTTTCCCGGTGGCACCATTACCGGTTGCCCGAAGGTGCGCTGCATGC
AGGTCATCGCCGAGCTCGAACAAACTGCGCGCGGGGCCTATACCGGTGCATTCGGCTGGCTCAATCGTGATGGCGACATG
GATCTGAATATCCTGATCCGCACCGCCGAGGTGGCCGGTCACCATGTGCATTTCCGCACCGGTGCCGGGATCGTGGTGGA
TTCGGATCCGCAGCGCGAGCTGGATGAAACCCGCGCCAAGGCGCGTGGCGTGTTGCGTGCGATCGAGCAGACATGA

Upstream 100 bases:

>100_bases
TTGCGGGTTGATGTTCAATCCTGCGATCAACCGTTGATCCACTCCTCGCGCGTGCTGCGTACGGCAGCGGTGCGTCCGTA
TCTCACGCCATGCCGGACCG

Downstream 100 bases:

>100_bases
GCGCTTCAACGGGACATCACCGGCGCGCGGTATCCTGCGCGGCGCAGGGGCAATGACGAGGTGGGTGTGGCGGTGACTGG
CAAACGCGGATGTCTGGCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTLTRSLHADIDLLALHRLSPQRYPALLESSASGTEHGRWDVLLLAEGPCLRLDPDGCTRDGAGRLLEGGFLAALDAAWQ
AERVPHDAASPWPFRGGWAVLLDYELAAQVEPILQLPTRRDGVPTALALRAPAAVLRDRLHGRCVALAEPGREELLQQIG
DDLAACAALPPLPAWAGPLAVDEEAPERFTGAVERVLDYLRAGDVFQANISRAWHAAFAAVVDPAALHARLRAANPAPFA
GLFVAAGRAVASSSPERLVSVQGDVVQTRPIAGTRARFAGDDDAARIRELVGHPKERAEHVMLIDLERNDLGRICAPGTV
EVDELMCVESYAHVHHIVSNVRGRLRAGVTPGEVIAAVFPGGTITGCPKVRCMQVIAELEQTARGAYTGAFGWLNRDGDM
DLNILIRTAEVAGHHVHFRTGAGIVVDSDPQRELDETRAKARGVLRAIEQT

Sequences:

>Translated_451_residues
MTLTRSLHADIDLLALHRLSPQRYPALLESSASGTEHGRWDVLLLAEGPCLRLDPDGCTRDGAGRLLEGGFLAALDAAWQ
AERVPHDAASPWPFRGGWAVLLDYELAAQVEPILQLPTRRDGVPTALALRAPAAVLRDRLHGRCVALAEPGREELLQQIG
DDLAACAALPPLPAWAGPLAVDEEAPERFTGAVERVLDYLRAGDVFQANISRAWHAAFAAVVDPAALHARLRAANPAPFA
GLFVAAGRAVASSSPERLVSVQGDVVQTRPIAGTRARFAGDDDAARIRELVGHPKERAEHVMLIDLERNDLGRICAPGTV
EVDELMCVESYAHVHHIVSNVRGRLRAGVTPGEVIAAVFPGGTITGCPKVRCMQVIAELEQTARGAYTGAFGWLNRDGDM
DLNILIRTAEVAGHHVHFRTGAGIVVDSDPQRELDETRAKARGVLRAIEQT
>Mature_450_residues
TLTRSLHADIDLLALHRLSPQRYPALLESSASGTEHGRWDVLLLAEGPCLRLDPDGCTRDGAGRLLEGGFLAALDAAWQA
ERVPHDAASPWPFRGGWAVLLDYELAAQVEPILQLPTRRDGVPTALALRAPAAVLRDRLHGRCVALAEPGREELLQQIGD
DLAACAALPPLPAWAGPLAVDEEAPERFTGAVERVLDYLRAGDVFQANISRAWHAAFAAVVDPAALHARLRAANPAPFAG
LFVAAGRAVASSSPERLVSVQGDVVQTRPIAGTRARFAGDDDAARIRELVGHPKERAEHVMLIDLERNDLGRICAPGTVE
VDELMCVESYAHVHHIVSNVRGRLRAGVTPGEVIAAVFPGGTITGCPKVRCMQVIAELEQTARGAYTGAFGWLNRDGDMD
LNILIRTAEVAGHHVHFRTGAGIVVDSDPQRELDETRAKARGVLRAIEQT

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=265, Percent_Identity=37.3584905660377, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1787518, Length=419, Percent_Identity=34.1288782816229, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI87082077, Length=300, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786809, Length=242, Percent_Identity=26.4462809917355, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=446, Percent_Identity=31.390134529148, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324361, Length=395, Percent_Identity=25.5696202531646, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR010118 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 48480; Mature: 48348

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTRSLHADIDLLALHRLSPQRYPALLESSASGTEHGRWDVLLLAEGPCLRLDPDGCTR
CCCCCCHHCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEECCCCCCC
DGAGRLLEGGFLAALDAAWQAERVPHDAASPWPFRGGWAVLLDYELAAQVEPILQLPTRR
CCCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCC
DGVPTALALRAPAAVLRDRLHGRCVALAEPGREELLQQIGDDLAACAALPPLPAWAGPLA
CCCCCHHHHHCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
VDEEAPERFTGAVERVLDYLRAGDVFQANISRAWHAAFAAVVDPAALHARLRAANPAPFA
CCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHH
GLFVAAGRAVASSSPERLVSVQGDVVQTRPIAGTRARFAGDDDAARIRELVGHPKERAEH
HHHHHHCHHHHCCCCHHEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHCCE
VMLIDLERNDLGRICAPGTVEVDELMCVESYAHVHHIVSNVRGRLRAGVTPGEVIAAVFP
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEC
GGTITGCPKVRCMQVIAELEQTARGAYTGAFGWLNRDGDMDLNILIRTAEVAGHHVHFRT
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEHHCCCEEEEEC
GAGIVVDSDPQRELDETRAKARGVLRAIEQT
CCEEEECCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLTRSLHADIDLLALHRLSPQRYPALLESSASGTEHGRWDVLLLAEGPCLRLDPDGCTR
CCCCCHHCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEECCCCCCC
DGAGRLLEGGFLAALDAAWQAERVPHDAASPWPFRGGWAVLLDYELAAQVEPILQLPTRR
CCCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCC
DGVPTALALRAPAAVLRDRLHGRCVALAEPGREELLQQIGDDLAACAALPPLPAWAGPLA
CCCCCHHHHHCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
VDEEAPERFTGAVERVLDYLRAGDVFQANISRAWHAAFAAVVDPAALHARLRAANPAPFA
CCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHH
GLFVAAGRAVASSSPERLVSVQGDVVQTRPIAGTRARFAGDDDAARIRELVGHPKERAEH
HHHHHHCHHHHCCCCHHEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHCCE
VMLIDLERNDLGRICAPGTVEVDELMCVESYAHVHHIVSNVRGRLRAGVTPGEVIAAVFP
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEC
GGTITGCPKVRCMQVIAELEQTARGAYTGAFGWLNRDGDMDLNILIRTAEVAGHHVHFRT
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEHHCCCEEEEEC
GAGIVVDSDPQRELDETRAKARGVLRAIEQT
CCEEEECCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]