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The map label for this gene is fabF [H]

Identifier: 21241884

GI number: 21241884

Start: 1278739

End: 1279974

Strand: Direct

Name: fabF [H]

Synonym: XAC1129

Alternate gene names: 21241884

Gene position: 1278739-1279974 (Clockwise)

Preceding gene: 21241883

Following gene: 21241885

Centisome position: 24.71

GC content: 63.92

Gene sequence:

>1236_bases
ATGAGTCGTCGTGTTGTCGTTACCGGCATGGGCATGGTGTCGCCGCTGGGCAATGATCTGGCCACCAGCTGGGACGGAAT
CGTCCACGGCCGCTCAGGCATTGGCCCGATCACGCAGATCGATGCCTCGCAGTTCACCACCAAGATCGCCGGTGAAATCA
AGAATTTCGACCCCACGCTTTTTGTGTCCGCCAAGGACGTCAAGAAGATGGATTCGTTCATCCACTACGGTGTCGGCGCC
TCGTTCATGGCGCTGGACGATTCCGGACTGGAAATCGACGAAAGCAATGCCGAACGCGTGGGCGCCATTCTCGGCTCCGG
CATCGGCGGGCTGCTCGGCATTGAAGAGCAGACCATCAAATTCCATGAGGGCGGCGCGCGCAAGATTTCGCCGTTCTATG
TGCCCAGCACCATCATCAACATGCTGCCCGGCCAGGTGAGCCTGATCAAAGGCCTGAAAGGCCCGACGTTCTCGGCTGTA
TCGGCCTGCGCCACATCCAACCATTCGATCGGCACCGCGATGCGCATGATCCAGCACGGCGATGCCGATGTGATGCTGGC
TGGCGGTGCCGAGCGCGGTTCGTCGCCGAGTTCGGTGGGCGGCTTTTGTGCGATGAAAGCGATGTCCACCCGTAACGACG
ACCCGGCCGGCGCGTCGCGGCCGTGGGACAAGCAGCGCGATGGCTTCGTGCTGGGCGACGGCGCCGGCGTGCTGGTGCTG
GAGGAGTACGAACACGCCAAGGCGCGTGGCGCACGCATCTATGCCGAGCTGGTCGGCTTCGGCGCCAGTTCCGATGCGTT
TCACATGACCGCCCCCAGCGAAGACGGCGAGGGCGCGGCGCGCAGCATGGCGGCAGCGATGCGCGACGCCAAGCTCAACC
CCGAGCAGATCGGCTACCTCAACGCGCACGGCACCTCCACGCCGCTGGGCGATCTGGCCGAAACGATGGCGATGAAGCGC
GCGCTGGGCGATCACGCCTACAAGACCATGGTGAGCTCGACCAAGTCGATGACGGGGCATCTGCTCGGCGCGGCCGGCGG
TGTGGAAGCGATCTTCTCGGTGATGGCGCTGCACACCGGCATCATCCCGCCGACCATCAACCTGGAAGAGCCAAGCGAAG
GCTGCGACCTGGATTACGTGCCGAACGTGGCGCGCCAGGTGCAGGTGGATGCGGTGATGTCCAACGGCTTCGGCTTTGGC
GGCACCAACGGCACGCTGGTGTTCAAGCGCGTTTGA

Upstream 100 bases:

>100_bases
CGCATCAGACATTCCATGGGGCCGCTGATGCGGCCCTGTGTTTTTCAAGTGTCACCCGCAAACCCCAAGCACCGTCCGTT
CCGTGGTGAGGAGATCTGCA

Downstream 100 bases:

>100_bases
CCCCGCATATCGGTCGCGTGGCGTCATCGGCGCGCGACCTGCCTGGCTGTCGCATGCACTGCCGGCTTGCGGGTTGATGT
TCAATCCTGCGATCAACCGT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSRRVVVTGMGMVSPLGNDLATSWDGIVHGRSGIGPITQIDASQFTTKIAGEIKNFDPTLFVSAKDVKKMDSFIHYGVGA
SFMALDDSGLEIDESNAERVGAILGSGIGGLLGIEEQTIKFHEGGARKISPFYVPSTIINMLPGQVSLIKGLKGPTFSAV
SACATSNHSIGTAMRMIQHGDADVMLAGGAERGSSPSSVGGFCAMKAMSTRNDDPAGASRPWDKQRDGFVLGDGAGVLVL
EEYEHAKARGARIYAELVGFGASSDAFHMTAPSEDGEGAARSMAAAMRDAKLNPEQIGYLNAHGTSTPLGDLAETMAMKR
ALGDHAYKTMVSSTKSMTGHLLGAAGGVEAIFSVMALHTGIIPPTINLEEPSEGCDLDYVPNVARQVQVDAVMSNGFGFG
GTNGTLVFKRV

Sequences:

>Translated_411_residues
MSRRVVVTGMGMVSPLGNDLATSWDGIVHGRSGIGPITQIDASQFTTKIAGEIKNFDPTLFVSAKDVKKMDSFIHYGVGA
SFMALDDSGLEIDESNAERVGAILGSGIGGLLGIEEQTIKFHEGGARKISPFYVPSTIINMLPGQVSLIKGLKGPTFSAV
SACATSNHSIGTAMRMIQHGDADVMLAGGAERGSSPSSVGGFCAMKAMSTRNDDPAGASRPWDKQRDGFVLGDGAGVLVL
EEYEHAKARGARIYAELVGFGASSDAFHMTAPSEDGEGAARSMAAAMRDAKLNPEQIGYLNAHGTSTPLGDLAETMAMKR
ALGDHAYKTMVSSTKSMTGHLLGAAGGVEAIFSVMALHTGIIPPTINLEEPSEGCDLDYVPNVARQVQVDAVMSNGFGFG
GTNGTLVFKRV
>Mature_410_residues
SRRVVVTGMGMVSPLGNDLATSWDGIVHGRSGIGPITQIDASQFTTKIAGEIKNFDPTLFVSAKDVKKMDSFIHYGVGAS
FMALDDSGLEIDESNAERVGAILGSGIGGLLGIEEQTIKFHEGGARKISPFYVPSTIINMLPGQVSLIKGLKGPTFSAVS
ACATSNHSIGTAMRMIQHGDADVMLAGGAERGSSPSSVGGFCAMKAMSTRNDDPAGASRPWDKQRDGFVLGDGAGVLVLE
EYEHAKARGARIYAELVGFGASSDAFHMTAPSEDGEGAARSMAAAMRDAKLNPEQIGYLNAHGTSTPLGDLAETMAMKRA
LGDHAYKTMVSSTKSMTGHLLGAAGGVEAIFSVMALHTGIIPPTINLEEPSEGCDLDYVPNVARQVQVDAVMSNGFGFGG
TNGTLVFKRV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=419, Percent_Identity=46.7780429594272, Blast_Score=367, Evalue=1e-102,
Organism=Homo sapiens, GI223972627, Length=166, Percent_Identity=50.6024096385542, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI41872631, Length=428, Percent_Identity=24.5327102803738, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1787337, Length=410, Percent_Identity=60, Blast_Score=477, Evalue=1e-136,
Organism=Escherichia coli, GI1788663, Length=421, Percent_Identity=40.3800475059382, Blast_Score=254, Evalue=8e-69,
Organism=Caenorhabditis elegans, GI71983541, Length=412, Percent_Identity=36.8932038834951, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=42.4242424242424, Blast_Score=199, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17550940, Length=416, Percent_Identity=25, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI212642053, Length=375, Percent_Identity=23.4666666666667, Blast_Score=107, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6320904, Length=446, Percent_Identity=39.237668161435, Blast_Score=295, Evalue=9e-81,
Organism=Drosophila melanogaster, GI24644341, Length=417, Percent_Identity=42.9256594724221, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI221330659, Length=371, Percent_Identity=25.3369272237197, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI19920632, Length=371, Percent_Identity=25.3369272237197, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24581345, Length=377, Percent_Identity=24.1379310344828, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42881; Mature: 42750

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRVVVTGMGMVSPLGNDLATSWDGIVHGRSGIGPITQIDASQFTTKIAGEIKNFDPTL
CCCEEEEECCCCCCCCCCHHHHCCCCEEECCCCCCCCEECCHHHHHHHHHHHHCCCCCEE
FVSAKDVKKMDSFIHYGVGASFMALDDSGLEIDESNAERVGAILGSGIGGLLGIEEQTIK
EEEHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHCCCCHHCCCCHHEEE
FHEGGARKISPFYVPSTIINMLPGQVSLIKGLKGPTFSAVSACATSNHSIGTAMRMIQHG
EECCCCCCCCCEECHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHCC
DADVMLAGGAERGSSPSSVGGFCAMKAMSTRNDDPAGASRPWDKQRDGFVLGDGAGVLVL
CCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
EEYEHAKARGARIYAELVGFGASSDAFHMTAPSEDGEGAARSMAAAMRDAKLNPEQIGYL
ECCHHHHHHHHHEEEHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHEEEE
NAHGTSTPLGDLAETMAMKRALGDHAYKTMVSSTKSMTGHLLGAAGGVEAIFSVMALHTG
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
IIPPTINLEEPSEGCDLDYVPNVARQVQVDAVMSNGFGFGGTNGTLVFKRV
CCCCCCCCCCCCCCCCCCCCCCHHHHEEHHHHHHCCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
SRRVVVTGMGMVSPLGNDLATSWDGIVHGRSGIGPITQIDASQFTTKIAGEIKNFDPTL
CCEEEEECCCCCCCCCCHHHHCCCCEEECCCCCCCCEECCHHHHHHHHHHHHCCCCCEE
FVSAKDVKKMDSFIHYGVGASFMALDDSGLEIDESNAERVGAILGSGIGGLLGIEEQTIK
EEEHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHCCCCHHCCCCHHEEE
FHEGGARKISPFYVPSTIINMLPGQVSLIKGLKGPTFSAVSACATSNHSIGTAMRMIQHG
EECCCCCCCCCEECHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHCC
DADVMLAGGAERGSSPSSVGGFCAMKAMSTRNDDPAGASRPWDKQRDGFVLGDGAGVLVL
CCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
EEYEHAKARGARIYAELVGFGASSDAFHMTAPSEDGEGAARSMAAAMRDAKLNPEQIGYL
ECCHHHHHHHHHEEEHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHEEEE
NAHGTSTPLGDLAETMAMKRALGDHAYKTMVSSTKSMTGHLLGAAGGVEAIFSVMALHTG
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
IIPPTINLEEPSEGCDLDYVPNVARQVQVDAVMSNGFGFGGTNGTLVFKRV
CCCCCCCCCCCCCCCCCCCCCCHHHHEEHHHHHHCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]