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The map label for this gene is 21241698

Identifier: 21241698

GI number: 21241698

Start: 1090032

End: 1091759

Strand: Direct

Name: 21241698

Synonym: XAC0928

Alternate gene names: NA

Gene position: 1090032-1091759 (Clockwise)

Preceding gene: 21241697

Following gene: 77748556

Centisome position: 21.06

GC content: 67.53

Gene sequence:

>1728_bases
ATGTCCAACGCGTCGTTTCGTCCGCGCCACCGAGCGCTCTGCATCCTGGGTGTTTCGGCACTTACCTCGCTGCTGCTGGT
AACGCCGGCATTCGCCGGCGATGTCTACCTGGGTGGCCTGGCCACTGCGCAGACCCACCAGAAGTTCATCGTGACCTACA
AGGACGGCAGTAGCGCCCTGAGCAGCCCCAGTGTGTTGACGACCTCGTTGCGCACCGCTGCACGTGCGTTGCCGGCCAAG
GCCGGCAAGTCGCTGGGCCTGAACAGCGTGCGTCGTCTGGCAGTGGGACCGGAGCTGGTTCAGGCCGACCGCGCGCTGGA
TCGCGCCGAAGCCGAAACCCTGATGCGCCAGCTGGCCGCCGACCCCAACGTGCAAAGCGTGGAAGTGGACCAGATGCTGT
ACCCCACGCTGACCCCCAACGACAGCCGCCTGTCCGAGCAGTGGGCCTTCGGCACCACCAACGCAGGGCTCAACATCCGC
CCGGCCTGGGACAAGGCCACCGGTGCCAACGTCGTGGTTGCGGTGATCGACACCGGCATCGTCAGCCATCCCGACCTGGA
CGCCAACATCCTGCCCGGCTACGACTTCATCAGCGATGCCACCGCCGCGCGCGACGGCAATGGGCGCGACAACAATCCTG
CCGACGAAGGCGACTGGAACTCGACCAGCGGGTGCGCCACGTCCAATTCCAGCTGGCACGGGACCCATGTCGCCGGCACG
GTGGCGGCGCTGACCAACAACACCACCGGCGTGGCCGGCACTGCGTTCAACGCCAAGGTGGTGCCGGTCCGCGTGCTGGG
CCGGTGCGGTGGTTCGCTGTCGGACATTGCCGATGCCATCATTTGGGCCTCCGGCGGCACCGTGAGCGGTGTGCCGGCCA
ATCCCAACGCGGCTGAAGTCATCAACATGTCGCTGGGCGGCGGTGGCACCTGTTCGTCCACGATGCAGAGCGCAATCAAC
GGCGCAGTCTCGCGCGGTACCACGGTGGTGGTGGCGGCCGGCAACAGTGCCGCCAACGTGTCCGGTTCGTTGCCGGCCAA
CTGCGCCAATGTGATCGCAGTGGCGGCCACGACCTCGGCCGGTGCCAAGGCCAGCTACTCCAACTACGGCAGCGGGATCG
ACGTCTCCGCGCCAGGGTCGGGGATCCTGTCCACGCTCAACAGCGGGACCACCACGCCGGGCAACGCCAGCTACGCTTCG
TACAACGGCACCTCGATGGCGGCGCCGCATGTGGCCGGCGTTGTTGCCCTCGTGCAGTCGGTTGCGCCCACCACGTTGAC
GCCTGCCGCAGTGGAAACACTGCTGAAGAACACCGCACGCGCCTTGCCGGGTGCCTGTTCGGGCGGTTGCGGTGCGGGCA
TCGTCGATGCCGATGCGGCAGTGACGGCGGCCATCGCCGGCAGCAGTGGCGGTGGCGGAACCGGCAACACCTTGACCAAC
GGCACGCCGGTGACCGGCCTCGGCGCGGCCACGGGCGCGGAGTTGAACTACACCATCTCGGTGCCGGCCGGCAGCGGCAC
GCTGACGGTCTCCACCAGCGGCGGCAGCGGCGATGCAGACCTGTACGTGCGGGCCGGTAGCGCGCCGACCGACACCGTCT
ACGCCTGCCGCCCGTATCTGGATGGCAATGCCGAAACCTGCAACATCGCCTCGCCGTCGGGAACCTATTACGTGCGGATC
AAGGCTTACAGCACGTTCTCCGGCGTGACCCTGACCGCCAGCTACTAA

Upstream 100 bases:

>100_bases
GGATCGATAACAGGGGCGGTCCGGGGCACTGGGCCAGTCGCCATTGCGACGGTTTCGGAACTACCGCTTCGGCGGTTCTC
TTGCACTGGAAGGGAATTCG

Downstream 100 bases:

>100_bases
ACGCTGGATCGCTGCACGCGTTCCCTGGCATGACGTCAGGGAACGCTGCCACCATCGCTTCAACCCCATTTGCGATACCT
CGCCCAGGTCTGCCGTTTCG

Product: extracellular protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MSNASFRPRHRALCILGVSALTSLLLVTPAFAGDVYLGGLATAQTHQKFIVTYKDGSSALSSPSVLTTSLRTAARALPAK
AGKSLGLNSVRRLAVGPELVQADRALDRAEAETLMRQLAADPNVQSVEVDQMLYPTLTPNDSRLSEQWAFGTTNAGLNIR
PAWDKATGANVVVAVIDTGIVSHPDLDANILPGYDFISDATAARDGNGRDNNPADEGDWNSTSGCATSNSSWHGTHVAGT
VAALTNNTTGVAGTAFNAKVVPVRVLGRCGGSLSDIADAIIWASGGTVSGVPANPNAAEVINMSLGGGGTCSSTMQSAIN
GAVSRGTTVVVAAGNSAANVSGSLPANCANVIAVAATTSAGAKASYSNYGSGIDVSAPGSGILSTLNSGTTTPGNASYAS
YNGTSMAAPHVAGVVALVQSVAPTTLTPAAVETLLKNTARALPGACSGGCGAGIVDADAAVTAAIAGSSGGGGTGNTLTN
GTPVTGLGAATGAELNYTISVPAGSGTLTVSTSGGSGDADLYVRAGSAPTDTVYACRPYLDGNAETCNIASPSGTYYVRI
KAYSTFSGVTLTASY

Sequences:

>Translated_575_residues
MSNASFRPRHRALCILGVSALTSLLLVTPAFAGDVYLGGLATAQTHQKFIVTYKDGSSALSSPSVLTTSLRTAARALPAK
AGKSLGLNSVRRLAVGPELVQADRALDRAEAETLMRQLAADPNVQSVEVDQMLYPTLTPNDSRLSEQWAFGTTNAGLNIR
PAWDKATGANVVVAVIDTGIVSHPDLDANILPGYDFISDATAARDGNGRDNNPADEGDWNSTSGCATSNSSWHGTHVAGT
VAALTNNTTGVAGTAFNAKVVPVRVLGRCGGSLSDIADAIIWASGGTVSGVPANPNAAEVINMSLGGGGTCSSTMQSAIN
GAVSRGTTVVVAAGNSAANVSGSLPANCANVIAVAATTSAGAKASYSNYGSGIDVSAPGSGILSTLNSGTTTPGNASYAS
YNGTSMAAPHVAGVVALVQSVAPTTLTPAAVETLLKNTARALPGACSGGCGAGIVDADAAVTAAIAGSSGGGGTGNTLTN
GTPVTGLGAATGAELNYTISVPAGSGTLTVSTSGGSGDADLYVRAGSAPTDTVYACRPYLDGNAETCNIASPSGTYYVRI
KAYSTFSGVTLTASY
>Mature_574_residues
SNASFRPRHRALCILGVSALTSLLLVTPAFAGDVYLGGLATAQTHQKFIVTYKDGSSALSSPSVLTTSLRTAARALPAKA
GKSLGLNSVRRLAVGPELVQADRALDRAEAETLMRQLAADPNVQSVEVDQMLYPTLTPNDSRLSEQWAFGTTNAGLNIRP
AWDKATGANVVVAVIDTGIVSHPDLDANILPGYDFISDATAARDGNGRDNNPADEGDWNSTSGCATSNSSWHGTHVAGTV
AALTNNTTGVAGTAFNAKVVPVRVLGRCGGSLSDIADAIIWASGGTVSGVPANPNAAEVINMSLGGGGTCSSTMQSAING
AVSRGTTVVVAAGNSAANVSGSLPANCANVIAVAATTSAGAKASYSNYGSGIDVSAPGSGILSTLNSGTTTPGNASYASY
NGTSMAAPHVAGVVALVQSVAPTTLTPAAVETLLKNTARALPGACSGGCGAGIVDADAAVTAAIAGSSGGGGTGNTLTNG
TPVTGLGAATGAELNYTISVPAGSGTLTVSTSGGSGDADLYVRAGSAPTDTVYACRPYLDGNAETCNIASPSGTYYVRIK
AYSTFSGVTLTASY

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI27894285, Length=407, Percent_Identity=28.7469287469287, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI299523015, Length=324, Percent_Identity=30.2469135802469, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI20336188, Length=407, Percent_Identity=28.7469287469287, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI20336190, Length=407, Percent_Identity=28.7469287469287, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI20336180, Length=407, Percent_Identity=28.7469287469287, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI4505577, Length=407, Percent_Identity=28.7469287469287, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI20336184, Length=407, Percent_Identity=28.7469287469287, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI20336182, Length=407, Percent_Identity=28.7469287469287, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI20336246, Length=324, Percent_Identity=30.2469135802469, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI20336186, Length=371, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI4505579, Length=370, Percent_Identity=26.7567567567568, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI76443679, Length=330, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI20336242, Length=342, Percent_Identity=26.0233918128655, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI295424143, Length=342, Percent_Identity=26.0233918128655, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71983555, Length=364, Percent_Identity=28.2967032967033, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI25141268, Length=364, Percent_Identity=28.2967032967033, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71988312, Length=364, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71988308, Length=326, Percent_Identity=28.2208588957055, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71988321, Length=369, Percent_Identity=27.10027100271, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71988315, Length=369, Percent_Identity=27.10027100271, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71988301, Length=369, Percent_Identity=27.10027100271, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71988297, Length=369, Percent_Identity=27.10027100271, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320775, Length=345, Percent_Identity=31.304347826087, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6324576, Length=327, Percent_Identity=28.1345565749235, Blast_Score=100, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6319893, Length=259, Percent_Identity=29.7297297297297, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24642488, Length=349, Percent_Identity=28.6532951289398, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24642484, Length=349, Percent_Identity=28.6532951289398, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24642486, Length=349, Percent_Identity=28.6532951289398, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281360987, Length=422, Percent_Identity=27.2511848341232, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642494, Length=346, Percent_Identity=29.1907514450867, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24642490, Length=346, Percent_Identity=29.1907514450867, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI45555723, Length=346, Percent_Identity=29.1907514450867, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24642492, Length=346, Percent_Identity=29.1907514450867, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI45553515, Length=359, Percent_Identity=27.2980501392758, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650056, Length=359, Percent_Identity=27.2980501392758, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650058, Length=359, Percent_Identity=27.2980501392758, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650060, Length=359, Percent_Identity=27.2980501392758, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45553513, Length=359, Percent_Identity=27.2980501392758, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17864552, Length=359, Percent_Identity=27.2980501392758, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281360985, Length=155, Percent_Identity=36.7741935483871, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 57067; Mature: 56935

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNASFRPRHRALCILGVSALTSLLLVTPAFAGDVYLGGLATAQTHQKFIVTYKDGSSAL
CCCCCCCCCHHEEEEEEHHHHHHHHHHCCCCCCCEEECCEEECCCCCEEEEEECCCCCCC
SSPSVLTTSLRTAARALPAKAGKSLGLNSVRRLAVGPELVQADRALDRAEAETLMRQLAA
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
DPNVQSVEVDQMLYPTLTPNDSRLSEQWAFGTTNAGLNIRPAWDKATGANVVVAVIDTGI
CCCCCEEEHHHEECCCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCCCCEEEEEEECCC
VSHPDLDANILPGYDFISDATAARDGNGRDNNPADEGDWNSTSGCATSNSSWHGTHVAGT
CCCCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEE
VAALTNNTTGVAGTAFNAKVVPVRVLGRCGGSLSDIADAIIWASGGTVSGVPANPNAAEV
EEEEECCCCCCEEECCCCEEEEEEEEECCCCCHHHHHHEEEEECCCEEECCCCCCCCEEE
INMSLGGGGTCSSTMQSAINGAVSRGTTVVVAAGNSAANVSGSLPANCANVIAVAATTSA
EEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCC
GAKASYSNYGSGIDVSAPGSGILSTLNSGTTTPGNASYASYNGTSMAAPHVAGVVALVQS
CCCCCCCCCCCCEEECCCCCHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHH
VAPTTLTPAAVETLLKNTARALPGACSGGCGAGIVDADAAVTAAIAGSSGGGGTGNTLTN
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCC
GTPVTGLGAATGAELNYTISVPAGSGTLTVSTSGGSGDADLYVRAGSAPTDTVYACRPYL
CCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCCEEEEECCC
DGNAETCNIASPSGTYYVRIKAYSTFSGVTLTASY
CCCCCEEEECCCCCEEEEEEEEEECCCCEEEEECC
>Mature Secondary Structure 
SNASFRPRHRALCILGVSALTSLLLVTPAFAGDVYLGGLATAQTHQKFIVTYKDGSSAL
CCCCCCCCHHEEEEEEHHHHHHHHHHCCCCCCCEEECCEEECCCCCEEEEEECCCCCCC
SSPSVLTTSLRTAARALPAKAGKSLGLNSVRRLAVGPELVQADRALDRAEAETLMRQLAA
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
DPNVQSVEVDQMLYPTLTPNDSRLSEQWAFGTTNAGLNIRPAWDKATGANVVVAVIDTGI
CCCCCEEEHHHEECCCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCCCCEEEEEEECCC
VSHPDLDANILPGYDFISDATAARDGNGRDNNPADEGDWNSTSGCATSNSSWHGTHVAGT
CCCCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEE
VAALTNNTTGVAGTAFNAKVVPVRVLGRCGGSLSDIADAIIWASGGTVSGVPANPNAAEV
EEEEECCCCCCEEECCCCEEEEEEEEECCCCCHHHHHHEEEEECCCEEECCCCCCCCEEE
INMSLGGGGTCSSTMQSAINGAVSRGTTVVVAAGNSAANVSGSLPANCANVIAVAATTSA
EEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCC
GAKASYSNYGSGIDVSAPGSGILSTLNSGTTTPGNASYASYNGTSMAAPHVAGVVALVQS
CCCCCCCCCCCCEEECCCCCHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHH
VAPTTLTPAAVETLLKNTARALPGACSGGCGAGIVDADAAVTAAIAGSSGGGGTGNTLTN
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCC
GTPVTGLGAATGAELNYTISVPAGSGTLTVSTSGGSGDADLYVRAGSAPTDTVYACRPYL
CCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCCEEEEECCC
DGNAETCNIASPSGTYYVRIKAYSTFSGVTLTASY
CCCCCEEEECCCCCEEEEEEEEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]