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The map label for this gene is gluP [H]

Identifier: 21241483

GI number: 21241483

Start: 845799

End: 847076

Strand: Direct

Name: gluP [H]

Synonym: XAC0712

Alternate gene names: 21241483

Gene position: 845799-847076 (Clockwise)

Preceding gene: 21241482

Following gene: 21241484

Centisome position: 16.34

GC content: 62.83

Gene sequence:

>1278_bases
ATGACTACCGCCAGGCCCGCAAACCCCGTTGTCTCGATCGCCATCGTCGGCGTGCTGTTTTTCATCATCGGCTTTTTCAC
CTGGATCAACGGGCCGCTGATCACCTTCGTGCGGCTGGCGTTCGACCTCAACGAGGTCAACGCATTCCTGGTGCTGATGG
TGTTCTACCTGTCGTACTTCTTTCTGGCCTTGCCCTCGTCGTGGATTCTCAAGCGCACCGGCATGAAGAAAGGCCTGGCG
CTGAGCCTGGTGGTGATGGCCGTGGGTGCAGCAGGCTTCGGCCAGTTCGCCACGCAGCGTTGGTATCCCGGCGCGCTGGG
CGGCCTATTCGTCATCGGCAGCGGCCTGGCCTTGCTGCAGACGGCGATCAACCCGTACATCAGCATTCTCGGGCCGATCG
AAAGTGCCGCGCGGCGTATCGCCTTGATGGGCATCTGCAACAAGATTGCCGGCATCCTGGCGCCGATCCTGATCGGCTCG
CTGGTGCTGCACGGTATCGGCGACCTGTCCGCGCAGGTGGCCAGTGCCGATGCGACGACCAAGGAAACCTTGCTCACCGC
CTTCGCCGCCAAGATTCACGCGCCGTATCTGGTGATGTCCGGCGTCCTGCTGTTGCTGGCCATTGGCGTGCTGTTCTCGC
CATTGCCCGAGCTCAAGCCCTCCGAAGCCAACGCCACGCCGGGCGCGACCGGTGGCGTGCAGAAATCCAGCATCTTCCAG
TTCCCGCACCTATGGCTGGGCGTGCTGTGCCTGTTCGTCTATGTGGGCGTGGAAGTGATGGCCGGCGATGCCATCGGCAC
CTACGGACACGGCTTCAATCTCCCGTTGGACAGCACCAAGATCTTCACCTCCTACACGCTGGGCGCGATGTTGCTGGGCT
ACATCGCCGGCCTGGTATTGATTCCGCGCGTGATCTCGCAGGCGCGTTACCTGAGCGTGTCGGCGGTGCTGGGCGTGCTG
TTCTCGCTCGGTGCCTTGTTCACCCACGGCTACGTGTCGGTGGGCTTCGTCGCCGCGCTCGGCTTTGCCAACGCGATGAT
GTGGCCGGCGATCTTTCCGCTGGCCATTCGCGGACTGGGCCGGTTCACCGAAATCGGCTCGGCATTGCTGGTGATGGGCA
TCGCTGGCGGCGCGATCATTCCGCAGCTGTTCGCCATCCTCAAGCAGCACTACGACTTCCAGGTCGTGTTCGCTGCACTG
ATGGTGCCGTGCTATCTGTACATCCTGTTCTATTCGCTGCGCGGTCATCGCGTGGGCCTGCCGGCCCAGGCCAAGTGA

Upstream 100 bases:

>100_bases
ACCGACACCTATTGCCACAACGACTTCTACGATTTCGTCGCCGAACTGCGCCGCTGACGCCAACGGCATTCCTTACGACA
ACCTCAGAGCCAGCCGATCC

Downstream 100 bases:

>100_bases
TCGCGGCGGCATGATGCGTTCCGACGGACAAGGTACATCCATGCGCAGGCCCACCATCAAAGATGTCGCCGAGCGCGCCA
AGGTCTCGTTGAAGACCGTG

Product: glucose-galactose transporter

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MTTARPANPVVSIAIVGVLFFIIGFFTWINGPLITFVRLAFDLNEVNAFLVLMVFYLSYFFLALPSSWILKRTGMKKGLA
LSLVVMAVGAAGFGQFATQRWYPGALGGLFVIGSGLALLQTAINPYISILGPIESAARRIALMGICNKIAGILAPILIGS
LVLHGIGDLSAQVASADATTKETLLTAFAAKIHAPYLVMSGVLLLLAIGVLFSPLPELKPSEANATPGATGGVQKSSIFQ
FPHLWLGVLCLFVYVGVEVMAGDAIGTYGHGFNLPLDSTKIFTSYTLGAMLLGYIAGLVLIPRVISQARYLSVSAVLGVL
FSLGALFTHGYVSVGFVAALGFANAMMWPAIFPLAIRGLGRFTEIGSALLVMGIAGGAIIPQLFAILKQHYDFQVVFAAL
MVPCYLYILFYSLRGHRVGLPAQAK

Sequences:

>Translated_425_residues
MTTARPANPVVSIAIVGVLFFIIGFFTWINGPLITFVRLAFDLNEVNAFLVLMVFYLSYFFLALPSSWILKRTGMKKGLA
LSLVVMAVGAAGFGQFATQRWYPGALGGLFVIGSGLALLQTAINPYISILGPIESAARRIALMGICNKIAGILAPILIGS
LVLHGIGDLSAQVASADATTKETLLTAFAAKIHAPYLVMSGVLLLLAIGVLFSPLPELKPSEANATPGATGGVQKSSIFQ
FPHLWLGVLCLFVYVGVEVMAGDAIGTYGHGFNLPLDSTKIFTSYTLGAMLLGYIAGLVLIPRVISQARYLSVSAVLGVL
FSLGALFTHGYVSVGFVAALGFANAMMWPAIFPLAIRGLGRFTEIGSALLVMGIAGGAIIPQLFAILKQHYDFQVVFAAL
MVPCYLYILFYSLRGHRVGLPAQAK
>Mature_424_residues
TTARPANPVVSIAIVGVLFFIIGFFTWINGPLITFVRLAFDLNEVNAFLVLMVFYLSYFFLALPSSWILKRTGMKKGLAL
SLVVMAVGAAGFGQFATQRWYPGALGGLFVIGSGLALLQTAINPYISILGPIESAARRIALMGICNKIAGILAPILIGSL
VLHGIGDLSAQVASADATTKETLLTAFAAKIHAPYLVMSGVLLLLAIGVLFSPLPELKPSEANATPGATGGVQKSSIFQF
PHLWLGVLCLFVYVGVEVMAGDAIGTYGHGFNLPLDSTKIFTSYTLGAMLLGYIAGLVLIPRVISQARYLSVSAVLGVLF
SLGALFTHGYVSVGFVAALGFANAMMWPAIFPLAIRGLGRFTEIGSALLVMGIAGGAIIPQLFAILKQHYDFQVVFAALM
VPCYLYILFYSLRGHRVGLPAQAK

Specific function: Intake of glucose and galactose (Potential) [H]

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=380, Percent_Identity=28.1578947368421, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005964
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45088; Mature: 44956

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTARPANPVVSIAIVGVLFFIIGFFTWINGPLITFVRLAFDLNEVNAFLVLMVFYLSYF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLALPSSWILKRTGMKKGLALSLVVMAVGAAGFGQFATQRWYPGALGGLFVIGSGLALLQ
HHHCCCHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHCCHHHHH
TAINPYISILGPIESAARRIALMGICNKIAGILAPILIGSLVLHGIGDLSAQVASADATT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KETLLTAFAAKIHAPYLVMSGVLLLLAIGVLFSPLPELKPSEANATPGATGGVQKSSIFQ
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHC
FPHLWLGVLCLFVYVGVEVMAGDAIGTYGHGFNLPLDSTKIFTSYTLGAMLLGYIAGLVL
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IPRVISQARYLSVSAVLGVLFSLGALFTHGYVSVGFVAALGFANAMMWPAIFPLAIRGLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFTEIGSALLVMGIAGGAIIPQLFAILKQHYDFQVVFAALMVPCYLYILFYSLRGHRVGL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEECC
PAQAK
CCCCC
>Mature Secondary Structure 
TTARPANPVVSIAIVGVLFFIIGFFTWINGPLITFVRLAFDLNEVNAFLVLMVFYLSYF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLALPSSWILKRTGMKKGLALSLVVMAVGAAGFGQFATQRWYPGALGGLFVIGSGLALLQ
HHHCCCHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHCCHHHHH
TAINPYISILGPIESAARRIALMGICNKIAGILAPILIGSLVLHGIGDLSAQVASADATT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KETLLTAFAAKIHAPYLVMSGVLLLLAIGVLFSPLPELKPSEANATPGATGGVQKSSIFQ
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHC
FPHLWLGVLCLFVYVGVEVMAGDAIGTYGHGFNLPLDSTKIFTSYTLGAMLLGYIAGLVL
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IPRVISQARYLSVSAVLGVLFSLGALFTHGYVSVGFVAALGFANAMMWPAIFPLAIRGLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFTEIGSALLVMGIAGGAIIPQLFAILKQHYDFQVVFAALMVPCYLYILFYSLRGHRVGL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEECC
PAQAK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9168605 [H]