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The map label for this gene is gmhA-2 [H]

Identifier: 57238459

GI number: 57238459

Start: 1511380

End: 1511985

Strand: Reverse

Name: gmhA-2 [H]

Synonym: CJE1609

Alternate gene names: 57238459

Gene position: 1511985-1511380 (Counterclockwise)

Preceding gene: 57238460

Following gene: 57238458

Centisome position: 85.05

GC content: 32.34

Gene sequence:

>606_bases
ATGGAGAATTTAAATTCTTATATAAAAGAACATTTTCAAGAATCAATTTTAGTAAAAGAGCAAATTTTAAAAGATGAGAA
TTTGATAACTCTTATTAAAAATGCTTCATTAGAAGTCATAAAAGCTTATAAAAATGGTAACAAAACTTTACTTGCAGGAA
ATGGTGGTAGTGCTGCAGATGCACAGCATATCGCAGGGGAATTTGTAAGTAGGTTTTATTTTGATAGACCCGGTATCGCA
AGTATTGCACTTACTACAGATACTAGCATATTAACAGCTATTGGCAATGACTATGGTTATGAAAATTTATTTGCAAGACA
AGTGCAAGCACAGGGTGTTAAAGGAGATGTTTTTATAGGAATTTCTACAAGTGGAAATAGTAAAAATATTTTAAAGGCTT
TAGAGCTTTGCAAGCAAAAAGAAATCATAAGCATAGGCTTAAGCGGAGCTAATGGCGGGGCTATGAATGAGCTTTGTGAT
TATTGTATAAAAGTACCTTCAACTTGCACACCAAGAATTCAAGAAGCACATATTTTAATAGGACATATTATTTGTGCTAT
CGTTGAAGAAGAGCTTTTTGGCAAAGGTTTTTCTTGCAAGCAATAA

Upstream 100 bases:

>100_bases
TCTTTGTAGATCCTACTAAAAAATACAACCTAATCAAAGCTTTAAGTAAAGAGCAAGGTTATGTGCAAGATTTTTCATTT
ACAAAAGAGGGGGTTAAATC

Downstream 100 bases:

>100_bases
TACTTTGTGGCGGCTTAGGAACAAGGCTTAAAAGTGTTATAAAAGACATTCCAAAGCCTATGGCACCGATAAATGATAAG
CCTTTTTTAGAATTTATTTT

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase 2 [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MENLNSYIKEHFQESILVKEQILKDENLITLIKNASLEVIKAYKNGNKTLLAGNGGSAADAQHIAGEFVSRFYFDRPGIA
SIALTTDTSILTAIGNDYGYENLFARQVQAQGVKGDVFIGISTSGNSKNILKALELCKQKEIISIGLSGANGGAMNELCD
YCIKVPSTCTPRIQEAHILIGHIICAIVEEELFGKGFSCKQ

Sequences:

>Translated_201_residues
MENLNSYIKEHFQESILVKEQILKDENLITLIKNASLEVIKAYKNGNKTLLAGNGGSAADAQHIAGEFVSRFYFDRPGIA
SIALTTDTSILTAIGNDYGYENLFARQVQAQGVKGDVFIGISTSGNSKNILKALELCKQKEIISIGLSGANGGAMNELCD
YCIKVPSTCTPRIQEAHILIGHIICAIVEEELFGKGFSCKQ
>Mature_201_residues
MENLNSYIKEHFQESILVKEQILKDENLITLIKNASLEVIKAYKNGNKTLLAGNGGSAADAQHIAGEFVSRFYFDRPGIA
SIALTTDTSILTAIGNDYGYENLFARQVQAQGVKGDVFIGISTSGNSKNILKALELCKQKEIISIGLSGANGGAMNELCD
YCIKVPSTCTPRIQEAHILIGHIICAIVEEELFGKGFSCKQ

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=193, Percent_Identity=40.4145077720207, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1786416, Length=186, Percent_Identity=39.7849462365591, Blast_Score=137, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 21789; Mature: 21789

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLNSYIKEHFQESILVKEQILKDENLITLIKNASLEVIKAYKNGNKTLLAGNGGSAAD
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHEECCCCEEEEECCCCCCHH
AQHIAGEFVSRFYFDRPGIASIALTTDTSILTAIGNDYGYENLFARQVQAQGVKGDVFIG
HHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEE
ISTSGNSKNILKALELCKQKEIISIGLSGANGGAMNELCDYCIKVPSTCTPRIQEAHILI
EECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
GHIICAIVEEELFGKGFSCKQ
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MENLNSYIKEHFQESILVKEQILKDENLITLIKNASLEVIKAYKNGNKTLLAGNGGSAAD
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHEECCCCEEEEECCCCCCHH
AQHIAGEFVSRFYFDRPGIASIALTTDTSILTAIGNDYGYENLFARQVQAQGVKGDVFIG
HHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEE
ISTSGNSKNILKALELCKQKEIISIGLSGANGGAMNELCDYCIKVPSTCTPRIQEAHILI
EECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
GHIICAIVEEELFGKGFSCKQ
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204; 12101286 [H]