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The map label for this gene is pabB [H]

Identifier: 57237703

GI number: 57237703

Start: 885307

End: 887091

Strand: Reverse

Name: pabB [H]

Synonym: CJE0949

Alternate gene names: 57237703

Gene position: 887091-885307 (Counterclockwise)

Preceding gene: 57237704

Following gene: 57237702

Centisome position: 49.9

GC content: 25.71

Gene sequence:

>1785_bases
GTGACTCTTGAAAACTATGCTGTTTTTGATAAATATTTTTACCATGATTTAAAACACACTTTAAAAGCCTTTAACCACAA
AGAAAGTAAAAAGTGCTTTAAATTTATAGAAAAATATAAAAATGATTTTTATATTTTAATGCTTGCTGATTATGAGCTAT
ATAGATATTTTCAAGATAAAAATTTCACAAGCAAAAAAGCTTATTTGTCTATATTTGCTTTTAAAAAAAGAAAAAAATTT
CAAAAAGAAGATATCGATGAAGAAAAATTTATTCCTGAATTTATAAATTTTTTAGATCAAGATAATTACAAAGAAAATTT
CATCAAGGTTAAAGAGGCAATCTCTAAAGGAAGAGTTTATCAAATCAACCTTACTCAAAATTTTAAATTTCATAGCAAAA
TGGATTCTTTTGAACTTTTTAAACTTTTGCTTTCTAGACAAGATACTGAATTTAAAGCTTTTATAAAAGATGAAACAAGA
GAAATTTTATCCTTTTCTCCTGAACTTTTCTTCAAAACCAAAAAAAGAAAAATATTTACAAAACCTATGAAAGGCACAAT
TAAGCGTGATAAAGATCCTATAAAAGATGAAGAAAATAAAATTTTCTTGCAAAATGATACAAAAAATCTGAGTGAAAATG
TTATGATTTGTGATCTTTTACGCAACGATCTTTCAAAAATCATCACAAAAAAAAGCTTAAAAACCAAACTTTTTGAAATT
CAAAGTCACCCTACTTTACATCAAATGACTTCAAGCGTACAAGGAAAACTTAAAAAAAATATTTCTTTATATCAAATTTT
TAAAGCTCTCTTTCCTTGTGGTTCTATTACAGGTGCTCCAAAGCTTGAAAGCATTAAATTTATTGAAGAATTAGAACAAA
GAGATCGTGGTATTTACTGCGGAACTATAGGTTTAATACACAAAAATAAAAATAAATTTAGCGTAGCCATACGCACCTTA
GAAAAACAAGATGAAATTTATACTTATAGCACGGGTAGCGGCTTAGTTTGGGACTCAAAATTCAAAGATGAATTTGAAGA
ATTAAAACTTAAAAGTGCAATCTTAAATCCTTGTGATTTTTATCTTTTTGAAACCATGTATTTTAAAAATTCTCAAATTT
TATTTTTAAAAGAACATTTATTAAGGCTTATAAATTCAGCTCTTAAATTTAATTTTAATACTCACAAGCTCTTTAAAGAT
TTTTATAATGTTTTAAATCAAAAAAGTTCTTATAAAGAATATCAAAATTTTACACTTTTTAAACTCGATGAAAAAATTTT
CCACAAAAAACACTCTTTATTTTATAATTTTCCCCTACCCTTTAAAAATCCACATAAAGAAGGAATTTTAAAGCTTATTT
TATACAGAGACGGAAGATACGAATTTCAACAAAGTGCCTTAAAACAAAATTCAAACGATATTTTGCTTTTAAGTGATGAT
AAAATTAACTCAAAAAGTGACAATCTCTATCACAAAAGCTCTTTACGTAGTTTTTATAATCAACACTCATACAAATGGCA
GCAAAACTTGTGTTATGACATAGCTTTTTTTAACGAAAAAGATGAACTTTGCGAAGGCTCAAGAACCAATCTCATCTTAG
AAAAAAACGCTCAATTTTATACTCCACAAATTCAAAGTGGTATGTTAAATGGCGTATATAGAAATTTCTTAGTCAATCTT
GGTTTGATAAAAGAAAAAGCATTATTTAAACAAGATTTATTTGAAGCAGAAAATATTTATTGCATTAATTCCGTGCGTGG
TTTAAAAAAGGTAAAATTACAATGA

Upstream 100 bases:

>100_bases
CAAGAAGCTTTAGGGCATGCAAGTTTAAATACCTCAAGAATTTACACTCATTTTGATAATGATAAATTAAAACTTGCCGC
ACAGGTTGCAAAGGAATTAA

Downstream 100 bases:

>100_bases
AGAAAATTTTATTTATAGATAATTATGATTCTTTTAGTTATACCATCATCTATTATCTTAAAGAACTTGGTTTTGAATGT
AAAGTGATAAAAAATGATGC

Product: para-aminobenzoate synthase glutamine amidotransferase, component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MTLENYAVFDKYFYHDLKHTLKAFNHKESKKCFKFIEKYKNDFYILMLADYELYRYFQDKNFTSKKAYLSIFAFKKRKKF
QKEDIDEEKFIPEFINFLDQDNYKENFIKVKEAISKGRVYQINLTQNFKFHSKMDSFELFKLLLSRQDTEFKAFIKDETR
EILSFSPELFFKTKKRKIFTKPMKGTIKRDKDPIKDEENKIFLQNDTKNLSENVMICDLLRNDLSKIITKKSLKTKLFEI
QSHPTLHQMTSSVQGKLKKNISLYQIFKALFPCGSITGAPKLESIKFIEELEQRDRGIYCGTIGLIHKNKNKFSVAIRTL
EKQDEIYTYSTGSGLVWDSKFKDEFEELKLKSAILNPCDFYLFETMYFKNSQILFLKEHLLRLINSALKFNFNTHKLFKD
FYNVLNQKSSYKEYQNFTLFKLDEKIFHKKHSLFYNFPLPFKNPHKEGILKLILYRDGRYEFQQSALKQNSNDILLLSDD
KINSKSDNLYHKSSLRSFYNQHSYKWQQNLCYDIAFFNEKDELCEGSRTNLILEKNAQFYTPQIQSGMLNGVYRNFLVNL
GLIKEKALFKQDLFEAENIYCINSVRGLKKVKLQ

Sequences:

>Translated_594_residues
MTLENYAVFDKYFYHDLKHTLKAFNHKESKKCFKFIEKYKNDFYILMLADYELYRYFQDKNFTSKKAYLSIFAFKKRKKF
QKEDIDEEKFIPEFINFLDQDNYKENFIKVKEAISKGRVYQINLTQNFKFHSKMDSFELFKLLLSRQDTEFKAFIKDETR
EILSFSPELFFKTKKRKIFTKPMKGTIKRDKDPIKDEENKIFLQNDTKNLSENVMICDLLRNDLSKIITKKSLKTKLFEI
QSHPTLHQMTSSVQGKLKKNISLYQIFKALFPCGSITGAPKLESIKFIEELEQRDRGIYCGTIGLIHKNKNKFSVAIRTL
EKQDEIYTYSTGSGLVWDSKFKDEFEELKLKSAILNPCDFYLFETMYFKNSQILFLKEHLLRLINSALKFNFNTHKLFKD
FYNVLNQKSSYKEYQNFTLFKLDEKIFHKKHSLFYNFPLPFKNPHKEGILKLILYRDGRYEFQQSALKQNSNDILLLSDD
KINSKSDNLYHKSSLRSFYNQHSYKWQQNLCYDIAFFNEKDELCEGSRTNLILEKNAQFYTPQIQSGMLNGVYRNFLVNL
GLIKEKALFKQDLFEAENIYCINSVRGLKKVKLQ
>Mature_593_residues
TLENYAVFDKYFYHDLKHTLKAFNHKESKKCFKFIEKYKNDFYILMLADYELYRYFQDKNFTSKKAYLSIFAFKKRKKFQ
KEDIDEEKFIPEFINFLDQDNYKENFIKVKEAISKGRVYQINLTQNFKFHSKMDSFELFKLLLSRQDTEFKAFIKDETRE
ILSFSPELFFKTKKRKIFTKPMKGTIKRDKDPIKDEENKIFLQNDTKNLSENVMICDLLRNDLSKIITKKSLKTKLFEIQ
SHPTLHQMTSSVQGKLKKNISLYQIFKALFPCGSITGAPKLESIKFIEELEQRDRGIYCGTIGLIHKNKNKFSVAIRTLE
KQDEIYTYSTGSGLVWDSKFKDEFEELKLKSAILNPCDFYLFETMYFKNSQILFLKEHLLRLINSALKFNFNTHKLFKDF
YNVLNQKSSYKEYQNFTLFKLDEKIFHKKHSLFYNFPLPFKNPHKEGILKLILYRDGRYEFQQSALKQNSNDILLLSDDK
INSKSDNLYHKSSLRSFYNQHSYKWQQNLCYDIAFFNEKDELCEGSRTNLILEKNAQFYTPQIQSGMLNGVYRNFLVNLG
LIKEKALFKQDLFEAENIYCINSVRGLKKVKLQ

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=289, Percent_Identity=32.5259515570934, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1787518, Length=257, Percent_Identity=27.6264591439689, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6320935, Length=254, Percent_Identity=28.740157480315, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324361, Length=307, Percent_Identity=27.6872964169381, Blast_Score=107, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 70987; Mature: 70856

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLENYAVFDKYFYHDLKHTLKAFNHKESKKCFKFIEKYKNDFYILMLADYELYRYFQDK
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHCC
NFTSKKAYLSIFAFKKRKKFQKEDIDEEKFIPEFINFLDQDNYKENFIKVKEAISKGRVY
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEE
QINLTQNFKFHSKMDSFELFKLLLSRQDTEFKAFIKDETREILSFSPELFFKTKKRKIFT
EEEECCCCCHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
KPMKGTIKRDKDPIKDEENKIFLQNDTKNLSENVMICDLLRNDLSKIITKKSLKTKLFEI
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSHPTLHQMTSSVQGKLKKNISLYQIFKALFPCGSITGAPKLESIKFIEELEQRDRGIYC
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
GTIGLIHKNKNKFSVAIRTLEKQDEIYTYSTGSGLVWDSKFKDEFEELKLKSAILNPCDF
EEEEEEEECCCCEEHHHHHHHCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHCCHHHH
YLFETMYFKNSQILFLKEHLLRLINSALKFNFNTHKLFKDFYNVLNQKSSYKEYQNFTLF
HHHHHHEECCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCEEE
KLDEKIFHKKHSLFYNFPLPFKNPHKEGILKLILYRDGRYEFQQSALKQNSNDILLLSDD
EECHHHHHHHHCEEEECCCCCCCCCHHHHEEEEEEECCCHHHHHHHHHCCCCCEEEEECC
KINSKSDNLYHKSSLRSFYNQHSYKWQQNLCYDIAFFNEKDELCEGSRTNLILEKNAQFY
CCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEEEEEEECCHHHHCCCCCCEEEEECCCCEE
TPQIQSGMLNGVYRNFLVNLGLIKEKALFKQDLFEAENIYCINSVRGLKKVKLQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHCCCC
>Mature Secondary Structure 
TLENYAVFDKYFYHDLKHTLKAFNHKESKKCFKFIEKYKNDFYILMLADYELYRYFQDK
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHCC
NFTSKKAYLSIFAFKKRKKFQKEDIDEEKFIPEFINFLDQDNYKENFIKVKEAISKGRVY
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEE
QINLTQNFKFHSKMDSFELFKLLLSRQDTEFKAFIKDETREILSFSPELFFKTKKRKIFT
EEEECCCCCHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
KPMKGTIKRDKDPIKDEENKIFLQNDTKNLSENVMICDLLRNDLSKIITKKSLKTKLFEI
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSHPTLHQMTSSVQGKLKKNISLYQIFKALFPCGSITGAPKLESIKFIEELEQRDRGIYC
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
GTIGLIHKNKNKFSVAIRTLEKQDEIYTYSTGSGLVWDSKFKDEFEELKLKSAILNPCDF
EEEEEEEECCCCEEHHHHHHHCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHCCHHHH
YLFETMYFKNSQILFLKEHLLRLINSALKFNFNTHKLFKDFYNVLNQKSSYKEYQNFTLF
HHHHHHEECCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCEEE
KLDEKIFHKKHSLFYNFPLPFKNPHKEGILKLILYRDGRYEFQQSALKQNSNDILLLSDD
EECHHHHHHHHCEEEECCCCCCCCCHHHHEEEEEEECCCHHHHHHHHHCCCCCEEEEECC
KINSKSDNLYHKSSLRSFYNQHSYKWQQNLCYDIAFFNEKDELCEGSRTNLILEKNAQFY
CCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEEEEEEECCHHHHCCCCCCEEEEECCCCEE
TPQIQSGMLNGVYRNFLVNLGLIKEKALFKQDLFEAENIYCINSVRGLKKVKLQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]