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The map label for this gene is pabA [H]

Identifier: 57237702

GI number: 57237702

Start: 884744

End: 885310

Strand: Reverse

Name: pabA [H]

Synonym: CJE0948

Alternate gene names: 57237702

Gene position: 885310-884744 (Counterclockwise)

Preceding gene: 57237703

Following gene: 57237700

Centisome position: 49.8

GC content: 25.4

Gene sequence:

>567_bases
ATGAAGAAAATTTTATTTATAGATAATTATGATTCTTTTAGTTATACCATCATCTATTATCTTAAAGAACTTGGTTTTGA
ATGTAAAGTGATAAAAAATGATGCCTTTAAAAAAGCTAAAGAATTAGAAAAATTTGATTTTACTCATCTTATCATCTCTC
CTGGCCCTCATTCTCCTAAGGAATCTAAATTAAGTTTAAAAGCAATCAAATATTTTAAAAAAAATAAAAAAATTTTAGGT
ATATGTTTAGGACATCAGTGTATAGCTGAAGTTTTTGGCGGCAGGGTTTCTAAAATGCAAAATCCCATGCATGGTAAAAT
TTCTAAACTTTATTTTAAAAAAGATCCTATTTTTAAGGGTATTAAAAAAGAAATTGAAATTTGCTTATATCATTCTTTAC
ACATCAGTTCTATGCCTGAAAAATGCAAAATTTTAGCTCATAATTCAGAAAATATTATTATGGCAATTAAACATAAAAAA
TATCCTATTTATGGATTGCAATTTCACCCTGAAGCGGTTTTAACTCAAAAAGGCAAAAAAATACTTAAAAACTTTATGAA
GCTTTAG

Upstream 100 bases:

>100_bases
GTTTGATAAAAGAAAAAGCATTATTTAAACAAGATTTATTTGAAGCAGAAAATATTTATTGCATTAATTCCGTGCGTGGT
TTAAAAAAGGTAAAATTACA

Downstream 100 bases:

>100_bases
TCTTTTTTGCATTTAAAATAACACTCAATATAATCAAAACAAAAGCAAAAATATCAAGCAAGCTATAACGGGTTTTTAAA
AATAAAAAACTCATTAAAGC

Product: para-aminobenzoate synthase glutamine amidotransferase, component II

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKKILFIDNYDSFSYTIIYYLKELGFECKVIKNDAFKKAKELEKFDFTHLIISPGPHSPKESKLSLKAIKYFKKNKKILG
ICLGHQCIAEVFGGRVSKMQNPMHGKISKLYFKKDPIFKGIKKEIEICLYHSLHISSMPEKCKILAHNSENIIMAIKHKK
YPIYGLQFHPEAVLTQKGKKILKNFMKL

Sequences:

>Translated_188_residues
MKKILFIDNYDSFSYTIIYYLKELGFECKVIKNDAFKKAKELEKFDFTHLIISPGPHSPKESKLSLKAIKYFKKNKKILG
ICLGHQCIAEVFGGRVSKMQNPMHGKISKLYFKKDPIFKGIKKEIEICLYHSLHISSMPEKCKILAHNSENIIMAIKHKK
YPIYGLQFHPEAVLTQKGKKILKNFMKL
>Mature_188_residues
MKKILFIDNYDSFSYTIIYYLKELGFECKVIKNDAFKKAKELEKFDFTHLIISPGPHSPKESKLSLKAIKYFKKNKKILG
ICLGHQCIAEVFGGRVSKMQNPMHGKISKLYFKKDPIFKGIKKEIEICLYHSLHISSMPEKCKILAHNSENIIMAIKHKK
YPIYGLQFHPEAVLTQKGKKILKNFMKL

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=140, Percent_Identity=35.7142857142857, Blast_Score=80, Evalue=9e-16,
Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=37.8378378378378, Blast_Score=156, Evalue=7e-40,
Organism=Escherichia coli, GI1787517, Length=189, Percent_Identity=32.8042328042328, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788854, Length=196, Percent_Identity=24.4897959183673, Blast_Score=74, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322638, Length=190, Percent_Identity=38.9473684210526, Blast_Score=147, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=25.7142857142857, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6323873, Length=183, Percent_Identity=28.9617486338798, Blast_Score=73, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281365319, Length=184, Percent_Identity=29.8913043478261, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 21856; Mature: 21856

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILFIDNYDSFSYTIIYYLKELGFECKVIKNDAFKKAKELEKFDFTHLIISPGPHSPK
CCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCEEEEECCCCCCCC
ESKLSLKAIKYFKKNKKILGICLGHQCIAEVFGGRVSKMQNPMHGKISKLYFKKDPIFKG
CHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHCCHHHHHCCCCCCCHHHEEECCCCHHHH
IKKEIEICLYHSLHISSMPEKCKILAHNSENIIMAIKHKKYPIYGLQFHPEAVLTQKGKK
HHHHHHHHHEEEECCCCCCCHHEEEEECCCCEEEEEECCCCCEEEEEECCHHHHHHHHHH
ILKNFMKL
HHHHHHCC
>Mature Secondary Structure
MKKILFIDNYDSFSYTIIYYLKELGFECKVIKNDAFKKAKELEKFDFTHLIISPGPHSPK
CCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCEEEEECCCCCCCC
ESKLSLKAIKYFKKNKKILGICLGHQCIAEVFGGRVSKMQNPMHGKISKLYFKKDPIFKG
CHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHCCHHHHHCCCCCCCHHHEEECCCCHHHH
IKKEIEICLYHSLHISSMPEKCKILAHNSENIIMAIKHKKYPIYGLQFHPEAVLTQKGKK
HHHHHHHHHEEEECCCCCCCHHEEEEECCCCEEEEEECCCCCEEEEEECCHHHHHHHHHH
ILKNFMKL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]