Click here to switch to the map view.

The map label for this gene is xerD [H]

Identifier: 57237704

GI number: 57237704

Start: 887081

End: 888145

Strand: Reverse

Name: xerD [H]

Synonym: CJE0950

Alternate gene names: 57237704

Gene position: 888145-887081 (Counterclockwise)

Preceding gene: 57237709

Following gene: 57237703

Centisome position: 49.96

GC content: 29.2

Gene sequence:

>1065_bases
ATGAAATACCCTTTAGATTGTGAAGAAAATTTTGAAAAATCATTCTTATTTTGGTTAGCAAAATATGTAAAATTTAAACT
CAACTCACTATCTAACAAAGAGTTAAAAAATCCACAAGCTTTAGCAGAAGTTAATTTTGCTCTTACAAAAGGTGTAAAAA
ATATTGATGAACTTGACGCTCTAACAAAAAAAGCAAGAAATGCTGGTTTAAGTGGAGTTAATACTTATTTTAATCCTTTA
AAAAAAGTATTTGAATATTTAAATTTTTATAAGCTTTACTCTTTAAAACAGATTGATGAAGAACTCATTGTAGAAGTTTT
AGCAAGTATAACAGGTGCTTTATCAGATGCAAGCAAAAAAAATTACCGTATTGCTGTGATTAATTTTTTTGATTTTTTAG
ACAAGCAAAATGAAGAAGATGAAAAAGCACATATTTTCGATATCAATCTTAAAAACTGGGCAGGTATAGCAGGTTCTAAA
GGGGTAAAATTACCTGAATTTATGAGTGAAGAAGAGCTTAAAAAATTTCTTGATGCTATTGAAAATGCAGATTTTAAAAA
CAATACCATACGCAATAAACTTATTATTAAAATCATCATTTTTACAGGCATACGGGTAAGTGAAGCTATCAATATCAAAA
TGGGTGATATTAGCGAAGAAAACGATCTTTATATCATAAGAATAAGAGCTAAAGGCAATAAATATCGTGTTGTAATGATA
AAAAAAGAACTTATTTACGATTTGCTTAAAAATGTAAGTATTAATTATATGAGTAAAGACGCCCTACTTTTTGTCAATAA
AAAAGGCACTCCACTGACTCAATCTTATGTCAGTCGCATAGTAGAACAGCTTTTATTTCGTGCAGGAATTCGCAAACAAA
AAAATGGTGCTCATATGTTGCGTCATACTTTTGCCACCCTGCTTTATAAAAAGCAAAAAGATTTAGTTTTAGTTCAAGAA
GCTTTAGGGCATGCAAGTTTAAATACCTCAAGAATTTACACTCATTTTGATAATGATAAATTAAAACTTGCCGCACAGGT
TGCAAAGGAATTAAGTGACTCTTGA

Upstream 100 bases:

>100_bases
AAAACAAACTTTTTCCTAAAAAAGCTTTTTTTTACTAAGTTAATACTAAAATACCTTTTCTAGTTAAAAAGCTAAAATTT
TAGATTTAGGAAAAGTTTTT

Downstream 100 bases:

>100_bases
AAACTATGCTGTTTTTGATAAATATTTTTACCATGATTTAAAACACACTTTAAAAGCCTTTAACCACAAAGAAAGTAAAA
AGTGCTTTAAATTTATAGAA

Product: phage integrase family site specific recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKYPLDCEENFEKSFLFWLAKYVKFKLNSLSNKELKNPQALAEVNFALTKGVKNIDELDALTKKARNAGLSGVNTYFNPL
KKVFEYLNFYKLYSLKQIDEELIVEVLASITGALSDASKKNYRIAVINFFDFLDKQNEEDEKAHIFDINLKNWAGIAGSK
GVKLPEFMSEEELKKFLDAIENADFKNNTIRNKLIIKIIIFTGIRVSEAINIKMGDISEENDLYIIRIRAKGNKYRVVMI
KKELIYDLLKNVSINYMSKDALLFVNKKGTPLTQSYVSRIVEQLLFRAGIRKQKNGAHMLRHTFATLLYKKQKDLVLVQE
ALGHASLNTSRIYTHFDNDKLKLAAQVAKELSDS

Sequences:

>Translated_354_residues
MKYPLDCEENFEKSFLFWLAKYVKFKLNSLSNKELKNPQALAEVNFALTKGVKNIDELDALTKKARNAGLSGVNTYFNPL
KKVFEYLNFYKLYSLKQIDEELIVEVLASITGALSDASKKNYRIAVINFFDFLDKQNEEDEKAHIFDINLKNWAGIAGSK
GVKLPEFMSEEELKKFLDAIENADFKNNTIRNKLIIKIIIFTGIRVSEAINIKMGDISEENDLYIIRIRAKGNKYRVVMI
KKELIYDLLKNVSINYMSKDALLFVNKKGTPLTQSYVSRIVEQLLFRAGIRKQKNGAHMLRHTFATLLYKKQKDLVLVQE
ALGHASLNTSRIYTHFDNDKLKLAAQVAKELSDS
>Mature_354_residues
MKYPLDCEENFEKSFLFWLAKYVKFKLNSLSNKELKNPQALAEVNFALTKGVKNIDELDALTKKARNAGLSGVNTYFNPL
KKVFEYLNFYKLYSLKQIDEELIVEVLASITGALSDASKKNYRIAVINFFDFLDKQNEEDEKAHIFDINLKNWAGIAGSK
GVKLPEFMSEEELKKFLDAIENADFKNNTIRNKLIIKIIIFTGIRVSEAINIKMGDISEENDLYIIRIRAKGNKYRVVMI
KKELIYDLLKNVSINYMSKDALLFVNKKGTPLTQSYVSRIVEQLLFRAGIRKQKNGAHMLRHTFATLLYKKQKDLVLVQE
ALGHASLNTSRIYTHFDNDKLKLAAQVAKELSDS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=301, Percent_Identity=29.5681063122924, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790244, Length=271, Percent_Identity=26.9372693726937, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 40661; Mature: 40661

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYPLDCEENFEKSFLFWLAKYVKFKLNSLSNKELKNPQALAEVNFALTKGVKNIDELDA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
LTKKARNAGLSGVNTYFNPLKKVFEYLNFYKLYSLKQIDEELIVEVLASITGALSDASKK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NYRIAVINFFDFLDKQNEEDEKAHIFDINLKNWAGIAGSKGVKLPEFMSEEELKKFLDAI
CCEEEEEEHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCHHHHHHHHHHH
ENADFKNNTIRNKLIIKIIIFTGIRVSEAINIKMGDISEENDLYIIRIRAKGNKYRVVMI
HCCCCCCCHHHHHHHEEEEECCCCEEEEEEEEEECCCCCCCCEEEEEEEECCCEEEEEEE
KKELIYDLLKNVSINYMSKDALLFVNKKGTPLTQSYVSRIVEQLLFRAGIRKQKNGAHML
HHHHHHHHHHCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
RHTFATLLYKKQKDLVLVQEALGHASLNTSRIYTHFDNDKLKLAAQVAKELSDS
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYPLDCEENFEKSFLFWLAKYVKFKLNSLSNKELKNPQALAEVNFALTKGVKNIDELDA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
LTKKARNAGLSGVNTYFNPLKKVFEYLNFYKLYSLKQIDEELIVEVLASITGALSDASKK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NYRIAVINFFDFLDKQNEEDEKAHIFDINLKNWAGIAGSKGVKLPEFMSEEELKKFLDAI
CCEEEEEEHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCHHHHHHHHHHH
ENADFKNNTIRNKLIIKIIIFTGIRVSEAINIKMGDISEENDLYIIRIRAKGNKYRVVMI
HCCCCCCCHHHHHHHEEEEECCCCEEEEEEEEEECCCCCCCCEEEEEEEECCCEEEEEEE
KKELIYDLLKNVSINYMSKDALLFVNKKGTPLTQSYVSRIVEQLLFRAGIRKQKNGAHML
HHHHHHHHHHCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
RHTFATLLYKKQKDLVLVQEALGHASLNTSRIYTHFDNDKLKLAAQVAKELSDS
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]