Click here to switch to the map view.

The map label for this gene is crp [C]

Identifier: 57237520

GI number: 57237520

Start: 469210

End: 469806

Strand: Direct

Name: crp [C]

Synonym: CJE0516

Alternate gene names: 57237520

Gene position: 469210-469806 (Clockwise)

Preceding gene: 57237518

Following gene: 57237521

Centisome position: 26.39

GC content: 22.95

Gene sequence:

>597_bases
ATGAAAGATTATTTAGAACTTTTATCTAGTGTAGGAAAATTAAAAAAATTTCAAAAAAATAGTATTTTATTTTATGAAGG
CGAAGAGGCTAAAAAATTTTTTATTTTACTCAAGGGAAAAATACGCATTTATAAAAGTACATCAAGTGATAAAGAAATTA
CTTTGCATTATTTTAATCCTCCAAATTTTATAGCAGAAATGCCTGCTTTTAAAAAATTAAATTATCCTGCTAATGCCATC
TTTGAAGAAGATGGAGAAATTTTGGAAATTGATTTTATTAATTTTCAAAATTTATGCAGTGAAAATAAAGAATTCAATTT
TTTACTTATCAGCTCACTTTTTGATAAAATCAAAATTTTAGAAAAGAAATTATCTCAAAATGCATTAGATTTAAGAACGA
GATTGTTAAAGTATCTTTTGGAAAATGAAAAAAAATTAGATACAATTTCACAAAAACAAATTGCAATTGATTTAAATGTT
AGAGCGCAATCTTTATCTCGAGTGTTAAAAGAGCTTAAAATTTCAGAACTTATTGATACAAAAAAAGGTAAAATTGAAAT
TTTAAATAAAGGTGTGATTATAAAAGAACTTTGGTAA

Upstream 100 bases:

>100_bases
TTCATATAAGCCTTTCTTGAATGTTAATTTTATGGCGTTAATATAGCAAAAATAAGATAAATTAAATTTAACATAAGTTA
AGAATGGAAAATATTATATA

Downstream 100 bases:

>100_bases
AATTTAAGGTAGAGAATGGATTTTGATTTTATATTAGCTCAAGCTCCCGCTTTTTTAACAGCTGCTTGGCTTACGATAAA
ACTAAGCTTTTTTGGAATTA

Product: transcriptional regulator

Products: NA

Alternate protein names: Transcription Regulator; Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator Crp/Fnr Family; CRP/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Crp Family Transcriptional Regulator; DNR Protein; Protein YieJ

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKDYLELLSSVGKLKKFQKNSILFYEGEEAKKFFILLKGKIRIYKSTSSDKEITLHYFNPPNFIAEMPAFKKLNYPANAI
FEEDGEILEIDFINFQNLCSENKEFNFLLISSLFDKIKILEKKLSQNALDLRTRLLKYLLENEKKLDTISQKQIAIDLNV
RAQSLSRVLKELKISELIDTKKGKIEILNKGVIIKELW

Sequences:

>Translated_198_residues
MKDYLELLSSVGKLKKFQKNSILFYEGEEAKKFFILLKGKIRIYKSTSSDKEITLHYFNPPNFIAEMPAFKKLNYPANAI
FEEDGEILEIDFINFQNLCSENKEFNFLLISSLFDKIKILEKKLSQNALDLRTRLLKYLLENEKKLDTISQKQIAIDLNV
RAQSLSRVLKELKISELIDTKKGKIEILNKGVIIKELW
>Mature_198_residues
MKDYLELLSSVGKLKKFQKNSILFYEGEEAKKFFILLKGKIRIYKSTSSDKEITLHYFNPPNFIAEMPAFKKLNYPANAI
FEEDGEILEIDFINFQNLCSENKEFNFLLISSLFDKIKILEKKLSQNALDLRTRLLKYLLENEKKLDTISQKQIAIDLNV
RAQSLSRVLKELKISELIDTKKGKIEILNKGVIIKELW

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 23143; Mature: 23143

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDYLELLSSVGKLKKFQKNSILFYEGEEAKKFFILLKGKIRIYKSTSSDKEITLHYFNP
CHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECEEEEEECCCCCCEEEEEEECC
PNFIAEMPAFKKLNYPANAIFEEDGEILEIDFINFQNLCSENKEFNFLLISSLFDKIKIL
CHHHHHCCCHHHCCCCCCCEECCCCCEEEEEECCHHHHHCCCCCCEEEEHHHHHHHHHHH
EKKLSQNALDLRTRLLKYLLENEKKLDTISQKQIAIDLNVRAQSLSRVLKELKISELIDT
HHHHCCCHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
KKGKIEILNKGVIIKELW
CCCCEEEEECCEEEEECC
>Mature Secondary Structure
MKDYLELLSSVGKLKKFQKNSILFYEGEEAKKFFILLKGKIRIYKSTSSDKEITLHYFNP
CHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECEEEEEECCCCCCEEEEEEECC
PNFIAEMPAFKKLNYPANAIFEEDGEILEIDFINFQNLCSENKEFNFLLISSLFDKIKIL
CHHHHHCCCHHHCCCCCCCEECCCCCEEEEEECCHHHHHCCCCCCEEEEHHHHHHHHHHH
EKKLSQNALDLRTRLLKYLLENEKKLDTISQKQIAIDLNVRAQSLSRVLKELKISELIDT
HHHHCCCHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
KKGKIEILNKGVIIKELW
CCCCEEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA