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The map label for this gene is mqo [H]

Identifier: 57237448

GI number: 57237448

Start: 397927

End: 399273

Strand: Reverse

Name: mqo [H]

Synonym: CJE0442

Alternate gene names: 57237448

Gene position: 399273-397927 (Counterclockwise)

Preceding gene: 57237449

Following gene: 57237447

Centisome position: 22.46

GC content: 31.7

Gene sequence:

>1347_bases
ATGGGTCAACAAGAATTTGATGTGCTTGTCATCGGAGCTGGAATTTCGGGAGCAGCATTATTTTACGAGCTTGCAAGATA
TACAAATATTAAAAATATTGCTTTGATAGAAAAATATAATACAGCTGCAACATTAAATTCTAAGGGAACGAGTAATTCTC
AAACCATTCATTGTGGAGATATTGAAACCAATTATACTTTAGAAAAAGCGCGAAAAGTAAAAAGAACAGCTGATATGATA
GTTAAATATGGACTCATGCAAAATGCGCAAAATAATTTCATGTTTTCTCATCAAAAAATGGCTCTAGCTGTTGGAGATAT
AGAATGTGATTATATGAAAAAACGCTATGAAGAATTTAAAGAACTTTATCCTTATATAAAATTTTTCGATAAAGCAAAAA
TCAAACAAATTGAACCCAAGGTTGTTTTAGGAGAAGATTGCAATCAAGATAGACCTGAAAATATCTGTGCCATGGGTGTT
GAAAGCGGCGAGGTTTTTACAACTGTAGATTTTGGGAAAATGAGTATAAATCTAATAGAACAAGCCCAAAAACAAAATAA
AAATACTTTCGTTGCCTTTAATCAAGAAATTATTCACATAGAAAAAAAAGATGATATTTTTATATTAAAAACCTCAAATC
ATCAAGAATACCATGCCAAAAGCGTAGTTGTCAATGCTGGGGCGCACTCTTTATATTTAGCACATAAAATGAACTTAGGT
ATGGATAAGTCTTGTTGGCCTGTTGCAGGAAGTTTTTATTTAACCAAACAAAAACTTTTAAATGGCAAAGTTTATATGGT
GCAAAATCCTAAACTTCCATTTGCAGCCCTTCATGGAGATCCTGATTTGCTTGCTGATATGAACACTCGCTTTGGACCTA
CTGCACTTGTTATTCCAAAACTAGAACGTTATCATGGTCTAAAATCAGTTCCAGAATTTTTTGAAGCACTAAAACTTGAT
AAAACTGTTTTAAAAGTAACTTTTAATATGTTTAAAGATGCAACAATTAGAAATTACATCTTTTATAATTATCTTTTTGA
ACTACCTTTTATTGATAAAAGCTTATTTGTTAAAGATGCCAAAAAAATAGTCCCAAGTCTTAAAGCAAGCGATATTTATT
ATGCGAAAGGTTTTGGAGGCGTAAGACCACAAGTTATTGATAAAACTAAAGGAGAATTAATGCTAGGTGAAGCAAGCATC
ACAGAAACCCCTGGTATTATTTTCAATATGACTCCAAGTCCTGGGGCAACAAGTTGTTTAGGAAATGCTGAAAGAGATGC
AAAGCTTATATGTAATTACCTAGGAATGGAATTTAACGAAGATAAATTTTCTTCAGAATTATTGTAA

Upstream 100 bases:

>100_bases
TCATTGATATCAAACCTTAATGAAATTTAACTTTTTGTAAAACAAATTCAATTAAACTTTATTTAGAAAAAAGTTTATTA
AAATAAAAAAAGGAAAAACA

Downstream 100 bases:

>100_bases
TCATTTTGTTTCTATTTTTAGCTACAATAATTTCAAAAGGAGTTTACCATGCTTAAAAAAACAAAAATTGTAGCCACAGT
AGGTCCAGCAAGTGAAAAGG

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone] [H]

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MGQQEFDVLVIGAGISGAALFYELARYTNIKNIALIEKYNTAATLNSKGTSNSQTIHCGDIETNYTLEKARKVKRTADMI
VKYGLMQNAQNNFMFSHQKMALAVGDIECDYMKKRYEEFKELYPYIKFFDKAKIKQIEPKVVLGEDCNQDRPENICAMGV
ESGEVFTTVDFGKMSINLIEQAQKQNKNTFVAFNQEIIHIEKKDDIFILKTSNHQEYHAKSVVVNAGAHSLYLAHKMNLG
MDKSCWPVAGSFYLTKQKLLNGKVYMVQNPKLPFAALHGDPDLLADMNTRFGPTALVIPKLERYHGLKSVPEFFEALKLD
KTVLKVTFNMFKDATIRNYIFYNYLFELPFIDKSLFVKDAKKIVPSLKASDIYYAKGFGGVRPQVIDKTKGELMLGEASI
TETPGIIFNMTPSPGATSCLGNAERDAKLICNYLGMEFNEDKFSSELL

Sequences:

>Translated_448_residues
MGQQEFDVLVIGAGISGAALFYELARYTNIKNIALIEKYNTAATLNSKGTSNSQTIHCGDIETNYTLEKARKVKRTADMI
VKYGLMQNAQNNFMFSHQKMALAVGDIECDYMKKRYEEFKELYPYIKFFDKAKIKQIEPKVVLGEDCNQDRPENICAMGV
ESGEVFTTVDFGKMSINLIEQAQKQNKNTFVAFNQEIIHIEKKDDIFILKTSNHQEYHAKSVVVNAGAHSLYLAHKMNLG
MDKSCWPVAGSFYLTKQKLLNGKVYMVQNPKLPFAALHGDPDLLADMNTRFGPTALVIPKLERYHGLKSVPEFFEALKLD
KTVLKVTFNMFKDATIRNYIFYNYLFELPFIDKSLFVKDAKKIVPSLKASDIYYAKGFGGVRPQVIDKTKGELMLGEASI
TETPGIIFNMTPSPGATSCLGNAERDAKLICNYLGMEFNEDKFSSELL
>Mature_447_residues
GQQEFDVLVIGAGISGAALFYELARYTNIKNIALIEKYNTAATLNSKGTSNSQTIHCGDIETNYTLEKARKVKRTADMIV
KYGLMQNAQNNFMFSHQKMALAVGDIECDYMKKRYEEFKELYPYIKFFDKAKIKQIEPKVVLGEDCNQDRPENICAMGVE
SGEVFTTVDFGKMSINLIEQAQKQNKNTFVAFNQEIIHIEKKDDIFILKTSNHQEYHAKSVVVNAGAHSLYLAHKMNLGM
DKSCWPVAGSFYLTKQKLLNGKVYMVQNPKLPFAALHGDPDLLADMNTRFGPTALVIPKLERYHGLKSVPEFFEALKLDK
TVLKVTFNMFKDATIRNYIFYNYLFELPFIDKSLFVKDAKKIVPSLKASDIYYAKGFGGVRPQVIDKTKGELMLGEASIT
ETPGIIFNMTPSPGATSCLGNAERDAKLICNYLGMEFNEDKFSSELL

Specific function: Catalyzes oxidation of malate to oxaloacetate in the citric acid cycle. Donates electrons to quinones of the electron transfer chain [H]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006231 [H]

Pfam domain/function: PF06039 Mqo [H]

EC number: =1.1.5.4 [H]

Molecular weight: Translated: 50585; Mature: 50454

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS00110 PYRUVATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQQEFDVLVIGAGISGAALFYELARYTNIKNIALIEKYNTAATLNSKGTSNSQTIHCGD
CCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCCCCCEEEECC
IETNYTLEKARKVKRTADMIVKYGLMQNAQNNFMFSHQKMALAVGDIECDYMKKRYEEFK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCHHHHHHHHHHHH
ELYPYIKFFDKAKIKQIEPKVVLGEDCNQDRPENICAMGVESGEVFTTVDFGKMSINLIE
HHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHH
QAQKQNKNTFVAFNQEIIHIEKKDDIFILKTSNHQEYHAKSVVVNAGAHSLYLAHKMNLG
HHHHCCCCEEEEECCEEEEEECCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEEECCCC
MDKSCWPVAGSFYLTKQKLLNGKVYMVQNPKLPFAALHGDPDLLADMNTRFGPTALVIPK
CCCCCCCCCCCEEEEHHHHHCCEEEEEECCCCCEEEECCCCHHHHCCCCCCCCEEEEECC
LERYHGLKSVPEFFEALKLDKTVLKVTFNMFKDATIRNYIFYNYLFELPFIDKSLFVKDA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEHHEECCCCCHHHHHHHH
KKIVPSLKASDIYYAKGFGGVRPQVIDKTKGELMLGEASITETPGIIFNMTPSPGATSCL
HHHHCCCCCCCEEEECCCCCCCCHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCCHHHC
GNAERDAKLICNYLGMEFNEDKFSSELL
CCCCCHHHHHHHHHCCCCCCCHHHHCCC
>Mature Secondary Structure 
GQQEFDVLVIGAGISGAALFYELARYTNIKNIALIEKYNTAATLNSKGTSNSQTIHCGD
CCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCCCCCEEEECC
IETNYTLEKARKVKRTADMIVKYGLMQNAQNNFMFSHQKMALAVGDIECDYMKKRYEEFK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCHHHHHHHHHHHH
ELYPYIKFFDKAKIKQIEPKVVLGEDCNQDRPENICAMGVESGEVFTTVDFGKMSINLIE
HHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHH
QAQKQNKNTFVAFNQEIIHIEKKDDIFILKTSNHQEYHAKSVVVNAGAHSLYLAHKMNLG
HHHHCCCCEEEEECCEEEEEECCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEEECCCC
MDKSCWPVAGSFYLTKQKLLNGKVYMVQNPKLPFAALHGDPDLLADMNTRFGPTALVIPK
CCCCCCCCCCCEEEEHHHHHCCEEEEEECCCCCEEEECCCCHHHHCCCCCCCCEEEEECC
LERYHGLKSVPEFFEALKLDKTVLKVTFNMFKDATIRNYIFYNYLFELPFIDKSLFVKDA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEHHEECCCCCHHHHHHHH
KKIVPSLKASDIYYAKGFGGVRPQVIDKTKGELMLGEASITETPGIIFNMTPSPGATSCL
HHHHCCCCCCCEEEECCCCCCCCHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCCHHHC
GNAERDAKLICNYLGMEFNEDKFSSELL
CCCCCHHHHHHHHHCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]