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The map label for this gene is coaX [H]

Identifier: 57237449

GI number: 57237449

Start: 399391

End: 400020

Strand: Reverse

Name: coaX [H]

Synonym: CJE0443

Alternate gene names: 57237449

Gene position: 400020-399391 (Counterclockwise)

Preceding gene: 57237450

Following gene: 57237448

Centisome position: 22.5

GC content: 27.46

Gene sequence:

>630_bases
ATGTTGCTCTGTGATATTGGGAATTCAAATGCTAATTTCCTAGATGATAACAAATATTTTACTCTTAGTATAGATCAGTT
TTTAGAATTTAAAAATGAACAAAAAATTTTTTATATCAATGTCAATGAACATCTCAAAGAACATTTAAAAAATCAAAAAA
AATTTATCAATCTTGAACCTTATTTTTTATTTGATACAATTTATCAAGGATTAGGAATCGATCGCATAGCAGCTTGTTAT
ACTATTGAAGATGGAGTTGTTGTAGATGCAGGTAGTGCTATTACAATTGATATTATTTCTAATTCTATACATCTTGGTGG
TTTTATCTTGCCAGGTATTGCAAATTATAAAAAAATTTATAGCCATATTTCACCACGATTAAAAAGTGAATTTAACACTC
AAGTTAGTCTTGATGCATTCCCACAAAAAACCATGGATGCTTTAAGTTATGGTGTTTTTAAAGGAATTTACCTACTGATA
AAAGATGCCGCTCAAAATAAAAAGCTTTATTTCACTGGTGGAGATGGGCAATTTTTAGCAAATTATTTCGATCACGCAAT
TTATGATAAACTTTTAATCTTTCGAGGAATGAAAAAGATTATAAAAGAAAATCCCAATTTACTTTATTAA

Upstream 100 bases:

>100_bases
CTAGCACAGCAAATTAACATAAATAACAAATATTTTTTTAGTATGGCTTCTCTTTGCTCTAAAGCAAAAAATCATCTAGA
AATGAAAGGATTTAATATCT

Downstream 100 bases:

>100_bases
AAATGTTACAAAAATTCTCATTGATATCAAACCTTAATGAAATTTAACTTTTTGTAAAACAAATTCAATTAAACTTTATT
TAGAAAAAAGTTTATTAAAA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MLLCDIGNSNANFLDDNKYFTLSIDQFLEFKNEQKIFYINVNEHLKEHLKNQKKFINLEPYFLFDTIYQGLGIDRIAACY
TIEDGVVVDAGSAITIDIISNSIHLGGFILPGIANYKKIYSHISPRLKSEFNTQVSLDAFPQKTMDALSYGVFKGIYLLI
KDAAQNKKLYFTGGDGQFLANYFDHAIYDKLLIFRGMKKIIKENPNLLY

Sequences:

>Translated_209_residues
MLLCDIGNSNANFLDDNKYFTLSIDQFLEFKNEQKIFYINVNEHLKEHLKNQKKFINLEPYFLFDTIYQGLGIDRIAACY
TIEDGVVVDAGSAITIDIISNSIHLGGFILPGIANYKKIYSHISPRLKSEFNTQVSLDAFPQKTMDALSYGVFKGIYLLI
KDAAQNKKLYFTGGDGQFLANYFDHAIYDKLLIFRGMKKIIKENPNLLY
>Mature_209_residues
MLLCDIGNSNANFLDDNKYFTLSIDQFLEFKNEQKIFYINVNEHLKEHLKNQKKFINLEPYFLFDTIYQGLGIDRIAACY
TIEDGVVVDAGSAITIDIISNSIHLGGFILPGIANYKKIYSHISPRLKSEFNTQVSLDAFPQKTMDALSYGVFKGIYLLI
KDAAQNKKLYFTGGDGQFLANYFDHAIYDKLLIFRGMKKIIKENPNLLY

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 23923; Mature: 23923

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLCDIGNSNANFLDDNKYFTLSIDQFLEFKNEQKIFYINVNEHLKEHLKNQKKFINLEP
CEEEEECCCCCCEECCCCEEEEEHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHEECCCC
YFLFDTIYQGLGIDRIAACYTIEDGVVVDAGSAITIDIISNSIHLGGFILPGIANYKKIY
HHHHHHHHHCCCCCHHEEEEEECCCEEEECCCEEEEEEECCCEEECCEECCCHHHHHHHH
SHISPRLKSEFNTQVSLDAFPQKTMDALSYGVFKGIYLLIKDAAQNKKLYFTGGDGQFLA
HHHCHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCHHHH
NYFDHAIYDKLLIFRGMKKIIKENPNLLY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLLCDIGNSNANFLDDNKYFTLSIDQFLEFKNEQKIFYINVNEHLKEHLKNQKKFINLEP
CEEEEECCCCCCEECCCCEEEEEHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHEECCCC
YFLFDTIYQGLGIDRIAACYTIEDGVVVDAGSAITIDIISNSIHLGGFILPGIANYKKIY
HHHHHHHHHCCCCCHHEEEEEECCCEEEECCCEEEEEEECCCEEECCEECCCHHHHHHHH
SHISPRLKSEFNTQVSLDAFPQKTMDALSYGVFKGIYLLIKDAAQNKKLYFTGGDGQFLA
HHHCHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCHHHH
NYFDHAIYDKLLIFRGMKKIIKENPNLLY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]