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The map label for this gene is 21228450

Identifier: 21228450

GI number: 21228450

Start: 2806291

End: 2807529

Strand: Reverse

Name: 21228450

Synonym: MM_2348

Alternate gene names: NA

Gene position: 2807529-2806291 (Counterclockwise)

Preceding gene: 21228452

Following gene: 21228449

Centisome position: 68.54

GC content: 43.34

Gene sequence:

>1239_bases
TTGTGGGTTTTAATTTTAAAGGGTATTAAAGGAAATTTTGATATGAATCCTGAAGAACCAAAAGACAAACCCTTCTCAGA
AGAAGGAAAAGAAGAAAAAGCTGACACCGTAGAGGGATCGGCTTCCGGGGATATGTATGTTCTGGACGACTCGGGGAGTG
TGACAAACGAGGAAGTCAGCAATGAAATTCTTGCAGCCGAGCTTAATGAGTGCGGGCTTGACCTTCTCAGGCTTGGAAAG
TATAACGAAGCAATAATTGCATTTGAAAAAGCAATTGACAAAGACCCGGGGAATATTTATCTATTAAATAATAAGGCAGC
AGCTCTTGAAAGTCTGGGAAGGTTTGAGGAAGCACTTAAACTATACCAGGAAGCTGTTAAGATCAATTCCGAAGATGCGG
ATCTCTGGAATAATATGGCTTTTTCTTACTCCCAGATAGGAGAATACGAAAAAGCAGTTGAAGCTTACGGAAAAGCCCTT
GATCTGAAGCCTGACTATCCAAACGCATGGTATGGAAAAGCCCTTAATCTCAGCCAGGCAGGAAGATATGAAGAAGCTGT
TGATGCCTATGATATAGTCCTGAAAGAAAACTCTAATTATAAGGAAGCATGGGCAGGAAAGGGCATAGCTCTCGGACAGA
TGGGAAACTACGATGAAGCTATAATTGCATACGATAAAGCCCTTGAAATCGACCCTGAATTCCTTGAAGCCTGGTATTAC
AAGGGAGTGGATCTTGACAGCCTTGGCAGTTTCAAGCAGGCTCTAAAAGCCTATGAAAAAGCCGTGGAAATCGACCCTGA
AAATGACGACGCCTGGAACAATATGGGCATTGACCTGGAAAACCTGGAAAGGTATGACGAAGCAATTAACGCTTTCGAAA
AAGCAATCGAAATAAATTCCGAAAATTCGGATGTCTGGTATAATAAAGGTTTTACTCTCAGCCAGGTACAGAGATTCGAT
GAAGCTGTCGAAGCCTACAGGAAAGCTGTACAGCTTGATCCCGAATACCTGGAAGCCTACTCCAGTCTGGGTTTTGTCCT
GGCTCAGCTCAAACGCTTTGAAGAAGCCCTGGATATCTATGAAAAAGCTCTTAAACTTGACCCTGAAGCTGCAGACTCCT
GGTTTGGAAAAGCTGTCTGCCTGAGTTACCTGGGGAGAGAAGAAGAAGCTGAAGATGCGTACAGAAAAGCCGTTGAAATT
GACCCCAGATATGCTGAAATCGGAGGGGACATACAGTAA

Upstream 100 bases:

>100_bases
CTACTTTTTAGGGAGAGGCTATAAAAGCCATAAAGGACAGATGTATAGATCATAAAGAACAATAGACTTAAGTAGGTAAC
GAACACGAATAGCCAGAAAA

Downstream 100 bases:

>100_bases
GCCGGAGAGATATTCTCTTTCCGGACCTTATTTTCGGACCTTGCAAGTAATTTTCCTTTATTATTTCTTATCCTTTACTC
CTTCATTTTTCTTACTCTTT

Product: O-linked N-acetylglucosamine transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MWVLILKGIKGNFDMNPEEPKDKPFSEEGKEEKADTVEGSASGDMYVLDDSGSVTNEEVSNEILAAELNECGLDLLRLGK
YNEAIIAFEKAIDKDPGNIYLLNNKAAALESLGRFEEALKLYQEAVKINSEDADLWNNMAFSYSQIGEYEKAVEAYGKAL
DLKPDYPNAWYGKALNLSQAGRYEEAVDAYDIVLKENSNYKEAWAGKGIALGQMGNYDEAIIAYDKALEIDPEFLEAWYY
KGVDLDSLGSFKQALKAYEKAVEIDPENDDAWNNMGIDLENLERYDEAINAFEKAIEINSENSDVWYNKGFTLSQVQRFD
EAVEAYRKAVQLDPEYLEAYSSLGFVLAQLKRFEEALDIYEKALKLDPEAADSWFGKAVCLSYLGREEEAEDAYRKAVEI
DPRYAEIGGDIQ

Sequences:

>Translated_412_residues
MWVLILKGIKGNFDMNPEEPKDKPFSEEGKEEKADTVEGSASGDMYVLDDSGSVTNEEVSNEILAAELNECGLDLLRLGK
YNEAIIAFEKAIDKDPGNIYLLNNKAAALESLGRFEEALKLYQEAVKINSEDADLWNNMAFSYSQIGEYEKAVEAYGKAL
DLKPDYPNAWYGKALNLSQAGRYEEAVDAYDIVLKENSNYKEAWAGKGIALGQMGNYDEAIIAYDKALEIDPEFLEAWYY
KGVDLDSLGSFKQALKAYEKAVEIDPENDDAWNNMGIDLENLERYDEAINAFEKAIEINSENSDVWYNKGFTLSQVQRFD
EAVEAYRKAVQLDPEYLEAYSSLGFVLAQLKRFEEALDIYEKALKLDPEAADSWFGKAVCLSYLGREEEAEDAYRKAVEI
DPRYAEIGGDIQ
>Mature_412_residues
MWVLILKGIKGNFDMNPEEPKDKPFSEEGKEEKADTVEGSASGDMYVLDDSGSVTNEEVSNEILAAELNECGLDLLRLGK
YNEAIIAFEKAIDKDPGNIYLLNNKAAALESLGRFEEALKLYQEAVKINSEDADLWNNMAFSYSQIGEYEKAVEAYGKAL
DLKPDYPNAWYGKALNLSQAGRYEEAVDAYDIVLKENSNYKEAWAGKGIALGQMGNYDEAIIAYDKALEIDPEFLEAWYY
KGVDLDSLGSFKQALKAYEKAVEIDPENDDAWNNMGIDLENLERYDEAINAFEKAIEINSENSDVWYNKGFTLSQVQRFD
EAVEAYRKAVQLDPEYLEAYSSLGFVLAQLKRFEEALDIYEKALKLDPEAADSWFGKAVCLSYLGREEEAEDAYRKAVEI
DPRYAEIGGDIQ

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=292, Percent_Identity=32.5342465753425, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI32307148, Length=292, Percent_Identity=32.5342465753425, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI310110582, Length=335, Percent_Identity=26.865671641791, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI310123097, Length=335, Percent_Identity=26.865671641791, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI310131789, Length=335, Percent_Identity=26.865671641791, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI301898023, Length=233, Percent_Identity=25.3218884120172, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI42476022, Length=233, Percent_Identity=25.3218884120172, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI170784867, Length=233, Percent_Identity=24.8927038626609, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI118766330, Length=256, Percent_Identity=26.5625, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI118766328, Length=256, Percent_Identity=26.5625, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI301336134, Length=295, Percent_Identity=26.4406779661017, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI83415184, Length=295, Percent_Identity=26.4406779661017, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI25952122, Length=295, Percent_Identity=26.1016949152542, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI224809432, Length=336, Percent_Identity=25.8928571428571, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI167466177, Length=342, Percent_Identity=23.9766081871345, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI167466175, Length=342, Percent_Identity=23.9766081871345, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI5803181, Length=308, Percent_Identity=22.0779220779221, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI296531396, Length=222, Percent_Identity=24.3243243243243, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI7706671, Length=266, Percent_Identity=24.4360902255639, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI262206280, Length=316, Percent_Identity=25.6329113924051, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI22749211, Length=298, Percent_Identity=25.503355704698, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI224028289, Length=328, Percent_Identity=24.6951219512195, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI24308141, Length=87, Percent_Identity=35.632183908046, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI221219056, Length=312, Percent_Identity=23.0769230769231, Blast_Score=66, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=291, Percent_Identity=32.3024054982818, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI115532692, Length=281, Percent_Identity=33.0960854092527, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17560436, Length=298, Percent_Identity=26.8456375838926, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71987213, Length=296, Percent_Identity=22.6351351351351, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25147174, Length=262, Percent_Identity=21.3740458015267, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71983707, Length=263, Percent_Identity=26.2357414448669, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71983711, Length=263, Percent_Identity=26.2357414448669, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17563052, Length=267, Percent_Identity=23.2209737827715, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193210476, Length=230, Percent_Identity=23.9130434782609, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25146105, Length=266, Percent_Identity=22.9323308270677, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319589, Length=337, Percent_Identity=24.0356083086053, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319387, Length=205, Percent_Identity=29.2682926829268, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320450, Length=235, Percent_Identity=22.9787234042553, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17647755, Length=292, Percent_Identity=30.8219178082192, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24585827, Length=292, Percent_Identity=30.8219178082192, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24585829, Length=292, Percent_Identity=30.8219178082192, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24656717, Length=335, Percent_Identity=27.1641791044776, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI18110006, Length=335, Percent_Identity=27.1641791044776, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24647123, Length=254, Percent_Identity=22.8346456692913, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI161076610, Length=332, Percent_Identity=24.6987951807229, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19920486, Length=332, Percent_Identity=24.6987951807229, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17137612, Length=271, Percent_Identity=23.6162361623616, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639187, Length=287, Percent_Identity=23.3449477351916, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24639189, Length=287, Percent_Identity=23.3449477351916, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17137540, Length=413, Percent_Identity=22.2760290556901, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24659892, Length=315, Percent_Identity=22.2222222222222, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI281364285, Length=336, Percent_Identity=24.1071428571429, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581187, Length=336, Percent_Identity=24.1071428571429, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17648033, Length=317, Percent_Identity=25.8675078864353, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584630, Length=317, Percent_Identity=25.5520504731861, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 46419; Mature: 46419

Theoretical pI: Translated: 4.00; Mature: 4.00

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWVLILKGIKGNFDMNPEEPKDKPFSEEGKEEKADTVEGSASGDMYVLDDSGSVTNEEVS
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCCHHHHH
NEILAAELNECGLDLLRLGKYNEAIIAFEKAIDKDPGNIYLLNNKAAALESLGRFEEALK
HHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHH
LYQEAVKINSEDADLWNNMAFSYSQIGEYEKAVEAYGKALDLKPDYPNAWYGKALNLSQA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCHHHC
GRYEEAVDAYDIVLKENSNYKEAWAGKGIALGQMGNYDEAIIAYDKALEIDPEFLEAWYY
CCHHHHHHHHHEEEECCCCHHHHHCCCCEEECCCCCCCCHHEEECCCCCCCHHHHHHHHH
KGVDLDSLGSFKQALKAYEKAVEIDPENDDAWNNMGIDLENLERYDEAINAFEKAIEINS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
ENSDVWYNKGFTLSQVQRFDEAVEAYRKAVQLDPEYLEAYSSLGFVLAQLKRFEEALDIY
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKALKLDPEAADSWFGKAVCLSYLGREEEAEDAYRKAVEIDPRYAEIGGDIQ
HHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHCCCCCCC
>Mature Secondary Structure
MWVLILKGIKGNFDMNPEEPKDKPFSEEGKEEKADTVEGSASGDMYVLDDSGSVTNEEVS
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCCHHHHH
NEILAAELNECGLDLLRLGKYNEAIIAFEKAIDKDPGNIYLLNNKAAALESLGRFEEALK
HHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHH
LYQEAVKINSEDADLWNNMAFSYSQIGEYEKAVEAYGKALDLKPDYPNAWYGKALNLSQA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCHHHC
GRYEEAVDAYDIVLKENSNYKEAWAGKGIALGQMGNYDEAIIAYDKALEIDPEFLEAWYY
CCHHHHHHHHHEEEECCCCHHHHHCCCCEEECCCCCCCCHHEEECCCCCCCHHHHHHHHH
KGVDLDSLGSFKQALKAYEKAVEIDPENDDAWNNMGIDLENLERYDEAINAFEKAIEINS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
ENSDVWYNKGFTLSQVQRFDEAVEAYRKAVQLDPEYLEAYSSLGFVLAQLKRFEEALDIY
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKALKLDPEAADSWFGKAVCLSYLGREEEAEDAYRKAVEIDPRYAEIGGDIQ
HHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]