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The map label for this gene is 21228452

Identifier: 21228452

GI number: 21228452

Start: 2808870

End: 2809748

Strand: Reverse

Name: 21228452

Synonym: MM_2350

Alternate gene names: NA

Gene position: 2809748-2808870 (Counterclockwise)

Preceding gene: 21228453

Following gene: 21228450

Centisome position: 68.59

GC content: 40.16

Gene sequence:

>879_bases
ATGACTTCGAACGAATGGTATAATAAAGGCATTGCACTCCAAGAATTAAAAAGGTACGGTGAAGCTCTGGATGCATTCGA
TAAGGCTCTGGAAATAAGCCCTGACAACGCAAAAATTTTGTTCAGCAAAGGAATTGCTCTTAAGAACCTGATGAAATACG
AAGAAGCTCTTCAAACTTTTGACAGGTCTCTTGAGATCAACCCTGCTGATGCCAGAGTCTGGTGTTTCAAAGCTGAAATT
CTTCTTGGCCTTATGCAGTATGAAGAGTCTCTTGACTCATTTTATAAGGCAGCAACTCTTGCTCCGGAAGACCCTGAGGT
ATGGTATAGAAGAGGGATGGCACTCAGGGAGATGAGGGCATATGAAGACGCGATGGATGACCTCGAAAAATCCATCCAGA
TCTATTCAAAGAAATATGACATTAACTCAATGAGTGCAAGCGAGTGGTGTAAAAAAGGCATGGGGCTTTGCAAAATAAAG
AGCTACAATGAAGCCCTTGATGCGTTTAACAGGGCACTTGAGTTAAACCCGAGTAACGGGAAAGCTCTGTACAACAAAGG
AATAGTTTTGCGCTGGCTCGGAAAAACCGATGAAGCAAAATTGTATATAGAAAAAGCAGTCGAGATTTTTGATAACAAAA
TTAAAGCAAATCCTGAAAATTCAAGGTTCTGGTATAACAAAGGAATTGCCCTGAGAGACCTGGAAAAATATAAAGAAGCA
CTTGATGCTTTTGAAAGAGCAATAGAAATCAACCCGAGCTTTACGAAAGCCTGGATTGGTAAAGGAATAGTATATGACAG
GGTTAAAAAACACCAGAAAGCGATGGAAGCATACGAAAGGGCAGTAGACATAAATCCAATATATTCAGACCTTATTTAA

Upstream 100 bases:

>100_bases
GTACAAAATGCATTTAACGCTCTGAAAGCATATAATATTGTTGTTCAAAGTGATGTGTGGTAAACGGTGGAAAATGTAGT
CAAAAAAGGTGTGGTGAGTT

Downstream 100 bases:

>100_bases
GCAGCCTTGCCAGTGGAGAGTCCTCCCCGAGAAACTGTGGGAGAGACAGAAAGCCGTTGACCGAAAAACAAATTCAAGTA
ACAGGTATAACGGCTAAAAT

Product: O-linked N-acetylglucosamine transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTSNEWYNKGIALQELKRYGEALDAFDKALEISPDNAKILFSKGIALKNLMKYEEALQTFDRSLEINPADARVWCFKAEI
LLGLMQYEESLDSFYKAATLAPEDPEVWYRRGMALREMRAYEDAMDDLEKSIQIYSKKYDINSMSASEWCKKGMGLCKIK
SYNEALDAFNRALELNPSNGKALYNKGIVLRWLGKTDEAKLYIEKAVEIFDNKIKANPENSRFWYNKGIALRDLEKYKEA
LDAFERAIEINPSFTKAWIGKGIVYDRVKKHQKAMEAYERAVDINPIYSDLI

Sequences:

>Translated_292_residues
MTSNEWYNKGIALQELKRYGEALDAFDKALEISPDNAKILFSKGIALKNLMKYEEALQTFDRSLEINPADARVWCFKAEI
LLGLMQYEESLDSFYKAATLAPEDPEVWYRRGMALREMRAYEDAMDDLEKSIQIYSKKYDINSMSASEWCKKGMGLCKIK
SYNEALDAFNRALELNPSNGKALYNKGIVLRWLGKTDEAKLYIEKAVEIFDNKIKANPENSRFWYNKGIALRDLEKYKEA
LDAFERAIEINPSFTKAWIGKGIVYDRVKKHQKAMEAYERAVDINPIYSDLI
>Mature_291_residues
TSNEWYNKGIALQELKRYGEALDAFDKALEISPDNAKILFSKGIALKNLMKYEEALQTFDRSLEINPADARVWCFKAEIL
LGLMQYEESLDSFYKAATLAPEDPEVWYRRGMALREMRAYEDAMDDLEKSIQIYSKKYDINSMSASEWCKKGMGLCKIKS
YNEALDAFNRALELNPSNGKALYNKGIVLRWLGKTDEAKLYIEKAVEIFDNKIKANPENSRFWYNKGIALRDLEKYKEAL
DAFERAIEINPSFTKAWIGKGIVYDRVKKHQKAMEAYERAVDINPIYSDLI

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=305, Percent_Identity=26.8852459016393, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI32307148, Length=305, Percent_Identity=26.8852459016393, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI224809432, Length=289, Percent_Identity=26.2975778546713, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI167466177, Length=174, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI167466175, Length=174, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI310123097, Length=315, Percent_Identity=23.1746031746032, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI310131789, Length=315, Percent_Identity=23.1746031746032, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI310110582, Length=315, Percent_Identity=23.1746031746032, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI189011544, Length=286, Percent_Identity=22.7272727272727, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=304, Percent_Identity=25, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115532692, Length=304, Percent_Identity=25, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319589, Length=289, Percent_Identity=23.5294117647059, Blast_Score=82, Evalue=8e-17,
Organism=Drosophila melanogaster, GI17647755, Length=321, Percent_Identity=25.5451713395639, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24585827, Length=321, Percent_Identity=25.5451713395639, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24585829, Length=321, Percent_Identity=25.5451713395639, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24647123, Length=268, Percent_Identity=25.7462686567164, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24656717, Length=267, Percent_Identity=22.4719101123595, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18110006, Length=267, Percent_Identity=22.4719101123595, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 33781; Mature: 33650

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNEWYNKGIALQELKRYGEALDAFDKALEISPDNAKILFSKGIALKNLMKYEEALQTF
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
DRSLEINPADARVWCFKAEILLGLMQYEESLDSFYKAATLAPEDPEVWYRRGMALREMRA
HHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHH
YEDAMDDLEKSIQIYSKKYDINSMSASEWCKKGMGLCKIKSYNEALDAFNRALELNPSNG
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECHHHHHHHHHHHHEECCCCCC
KALYNKGIVLRWLGKTDEAKLYIEKAVEIFDNKIKANPENSRFWYNKGIALRDLEKYKEA
CEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHH
LDAFERAIEINPSFTKAWIGKGIVYDRVKKHQKAMEAYERAVDINPIYSDLI
HHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure 
TSNEWYNKGIALQELKRYGEALDAFDKALEISPDNAKILFSKGIALKNLMKYEEALQTF
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
DRSLEINPADARVWCFKAEILLGLMQYEESLDSFYKAATLAPEDPEVWYRRGMALREMRA
HHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHH
YEDAMDDLEKSIQIYSKKYDINSMSASEWCKKGMGLCKIKSYNEALDAFNRALELNPSNG
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECHHHHHHHHHHHHEECCCCCC
KALYNKGIVLRWLGKTDEAKLYIEKAVEIFDNKIKANPENSRFWYNKGIALRDLEKYKEA
CEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHH
LDAFERAIEINPSFTKAWIGKGIVYDRVKKHQKAMEAYERAVDINPIYSDLI
HHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]