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The map label for this gene is rimK1 [H]

Identifier: 21228449

GI number: 21228449

Start: 2805023

End: 2805928

Strand: Reverse

Name: rimK1 [H]

Synonym: MM_2347

Alternate gene names: 21228449

Gene position: 2805928-2805023 (Counterclockwise)

Preceding gene: 21228450

Following gene: 21228443

Centisome position: 68.5

GC content: 47.46

Gene sequence:

>906_bases
ATGAAAGGATGGATTCTTTATAAGAGCACGGCTGCCGAACTCAAAAATGACCTGTACGAAATTAACCGCTTCATTAAGGT
TGCGGATGAAAAAAGAATAGAGCTCCGGGTTGTAAAACCTGACCAGTTCGACCTGATAGTAACAAGGGATGACAGGAAAA
GCATACTCCTCGACGGAGAAATTGTCCCCCTTCCTGACTTCCTCCTCCCGAGAATGGGAGCAGGTACAACCTACTTTGCG
CTTGCGGTCATCCGCCATCTCGAACGCCTGGGGGTCTGCGTCATTAATTCATCGCAGAGCATTGACACAGTCAGGGACAA
GCTTTATTCCCAGCAGATCCTTGCAGAAAGAGGAATTTCCTACCCCAATACAATGTTTGCCAAAAACCCTGTAAATATAA
GCCTGGTTGAAAAATACCTTGGATTTCCTCTCATAGTAAAAGCTCTCTCAGGCTCTATGGGAAAAGGCATCTTCCTTTCA
GAAAACCACGATAATTTCCGTGACCTGATGGAACTGATCCACATAACCAACCCCAGTGCAAACATAATCCTCCAGGAATT
CATTAAATCCAGCCTGGGAAGGGACCTCCGTGTCCTCGTAATTGGGGGAAGGGCAGTTGCCTGCATGGAACGCATAGCTC
CTGCTGGCAGTTTCAAGTCCAACTACTCCAGAGGCGGAACAGTACGAAAATTCGACATGACGCCTGAAGTAGAGGAGCTG
GCAACCGAGACTGCACGCACCTTCGGGCTGGACATAGCCGGCATCGACCTCTTATTCGACGGCGACCATTTCAAGGTTTG
TGAGGCTAATTCTTCCCCGGGCTTTGAAGGGCTTGAAAAATGCTGTGGAATTAATGTTGCAGGGATGATTTACGATTTTA
TCAGGAAAAAGGTGGATGAGAGATAA

Upstream 100 bases:

>100_bases
CAAAAGAAAAGAACAGCTCTATATGCTGGAAACGTTTTTTAGATAATCGAATGTCTTTTTTTAAATTTAAAGACACTTTT
GGGAAAGAGCGGATGAAAGG

Downstream 100 bases:

>100_bases
AATATGGATGAAAATTTTTTATTCATCTTTTCCCATTTCTTCAAAATAAAGTGATGATTAAGCCATTTGCTTAGAAGCTG
TACCAAGAAAAAATGCCTCC

Product: ribosomal protein S6 modification protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKGWILYKSTAAELKNDLYEINRFIKVADEKRIELRVVKPDQFDLIVTRDDRKSILLDGEIVPLPDFLLPRMGAGTTYFA
LAVIRHLERLGVCVINSSQSIDTVRDKLYSQQILAERGISYPNTMFAKNPVNISLVEKYLGFPLIVKALSGSMGKGIFLS
ENHDNFRDLMELIHITNPSANIILQEFIKSSLGRDLRVLVIGGRAVACMERIAPAGSFKSNYSRGGTVRKFDMTPEVEEL
ATETARTFGLDIAGIDLLFDGDHFKVCEANSSPGFEGLEKCCGINVAGMIYDFIRKKVDER

Sequences:

>Translated_301_residues
MKGWILYKSTAAELKNDLYEINRFIKVADEKRIELRVVKPDQFDLIVTRDDRKSILLDGEIVPLPDFLLPRMGAGTTYFA
LAVIRHLERLGVCVINSSQSIDTVRDKLYSQQILAERGISYPNTMFAKNPVNISLVEKYLGFPLIVKALSGSMGKGIFLS
ENHDNFRDLMELIHITNPSANIILQEFIKSSLGRDLRVLVIGGRAVACMERIAPAGSFKSNYSRGGTVRKFDMTPEVEEL
ATETARTFGLDIAGIDLLFDGDHFKVCEANSSPGFEGLEKCCGINVAGMIYDFIRKKVDER
>Mature_301_residues
MKGWILYKSTAAELKNDLYEINRFIKVADEKRIELRVVKPDQFDLIVTRDDRKSILLDGEIVPLPDFLLPRMGAGTTYFA
LAVIRHLERLGVCVINSSQSIDTVRDKLYSQQILAERGISYPNTMFAKNPVNISLVEKYLGFPLIVKALSGSMGKGIFLS
ENHDNFRDLMELIHITNPSANIILQEFIKSSLGRDLRVLVIGGRAVACMERIAPAGSFKSNYSRGGTVRKFDMTPEVEEL
ATETARTFGLDIAGIDLLFDGDHFKVCEANSSPGFEGLEKCCGINVAGMIYDFIRKKVDER

Specific function: Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 [H]

COG id: COG0189

COG function: function code HJ; Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI164663810, Length=280, Percent_Identity=31.0714285714286, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI134254462, Length=282, Percent_Identity=32.6241134751773, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1787076, Length=244, Percent_Identity=39.344262295082, Blast_Score=174, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013651
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR004666 [H]

Pfam domain/function: PF08443 RimK [H]

EC number: NA

Molecular weight: Translated: 33690; Mature: 33690

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGWILYKSTAAELKNDLYEINRFIKVADEKRIELRVVKPDQFDLIVTRDDRKSILLDGE
CCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCEEEECCC
IVPLPDFLLPRMGAGTTYFALAVIRHLERLGVCVINSSQSIDTVRDKLYSQQILAERGIS
EECCCHHHHHCCCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHCCCC
YPNTMFAKNPVNISLVEKYLGFPLIVKALSGSMGKGIFLSENHDNFRDLMELIHITNPSA
CCCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCCCCH
NIILQEFIKSSLGRDLRVLVIGGRAVACMERIAPAGSFKSNYSRGGTVRKFDMTPEVEEL
HHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHH
ATETARTFGLDIAGIDLLFDGDHFKVCEANSSPGFEGLEKCCGINVAGMIYDFIRKKVDE
HHHHHHHHCCEEEEEEEEEECCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCC
R
C
>Mature Secondary Structure
MKGWILYKSTAAELKNDLYEINRFIKVADEKRIELRVVKPDQFDLIVTRDDRKSILLDGE
CCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCEEEECCC
IVPLPDFLLPRMGAGTTYFALAVIRHLERLGVCVINSSQSIDTVRDKLYSQQILAERGIS
EECCCHHHHHCCCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHCCCC
YPNTMFAKNPVNISLVEKYLGFPLIVKALSGSMGKGIFLSENHDNFRDLMELIHITNPSA
CCCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCCCCH
NIILQEFIKSSLGRDLRVLVIGGRAVACMERIAPAGSFKSNYSRGGTVRKFDMTPEVEEL
HHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHH
ATETARTFGLDIAGIDLLFDGDHFKVCEANSSPGFEGLEKCCGINVAGMIYDFIRKKVDE
HHHHHHHHCCEEEEEEEEEECCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Glu; Ribosomal protein S6 [C]

Specific reaction: Catalyzes the addition of glutamic acids to the carboxyl end of ribosomal protein S6 [C]

General reaction: Ligases; Forming Carbon-Nitrogen Bonds; Acid-D-Amino-Acid Ligases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA