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The map label for this gene is bm3R1 [H]

Identifier: 21227716

GI number: 21227716

Start: 1925640

End: 1926218

Strand: Direct

Name: bm3R1 [H]

Synonym: MM_1614

Alternate gene names: 21227716

Gene position: 1925640-1926218 (Clockwise)

Preceding gene: 21227715

Following gene: 21227717

Centisome position: 47.01

GC content: 39.72

Gene sequence:

>579_bases
ATGAAAGAACATGTCAAAGACAAAAAAACAGCAATTATGGGAGCTGCCCTGAAGCTCTTCACTGAAAGAGGCTTCCACGG
TACGTCCACTGCTCAAATTTCAAAAAACGCAGGTGTAGCCACAGGCACCCTTTTCAATTACTTTCCCACAAAGGAAGATC
TTATAAACAGCCTTTATTTTGAGGTTAAAGGAAACTTGGGCCACTCTATGGGGGTAGGTCTCGAAGCTGAGACTACCTTT
CAGGATAAATTAAAAAGAATATGGTCAAATTTAGTCAATTGGGGTGTAAACAATCAGGAAGAATTCCTTTTTGTTGGACA
ATTCTGCTCTTCTCCTTACATAACAAAATTTACGCGTGATGAAGTGATGAAAGAATATGTCTTCCTCCATAATTTTGTGG
ATGAAGGGATAAAAACGGGAGAGGTTAGAGATTTTCCTGCGGAGCTGGTTATTGCAATGTTTTATCAGGGCAGCAGGGAG
GTAGTAAACCTTATTCTTGATTCAGATTCTTCACTGGATAAAAACAAAATCATAGCAGATGGATTCCAGATTCTCTGGAG
AGGTCTGGCTAAAGTGTAA

Upstream 100 bases:

>100_bases
ATATATAAAGAACAAAATTAAGAGTAAGTTCCATTAATTATTTATATTGTGATATAACTCAGTTCTATAACTGACTAATC
AGTCAATTTAGAGATAGTAT

Downstream 100 bases:

>100_bases
TTTTTTTCATTTCATGTGTGAGTGATCAGTCAATCAAAAACGGGCAAAACAATTTAAAAATTCAGGAGAACTAAAAATGC
TTTACAGAAAAATGCCCAAG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MKEHVKDKKTAIMGAALKLFTERGFHGTSTAQISKNAGVATGTLFNYFPTKEDLINSLYFEVKGNLGHSMGVGLEAETTF
QDKLKRIWSNLVNWGVNNQEEFLFVGQFCSSPYITKFTRDEVMKEYVFLHNFVDEGIKTGEVRDFPAELVIAMFYQGSRE
VVNLILDSDSSLDKNKIIADGFQILWRGLAKV

Sequences:

>Translated_192_residues
MKEHVKDKKTAIMGAALKLFTERGFHGTSTAQISKNAGVATGTLFNYFPTKEDLINSLYFEVKGNLGHSMGVGLEAETTF
QDKLKRIWSNLVNWGVNNQEEFLFVGQFCSSPYITKFTRDEVMKEYVFLHNFVDEGIKTGEVRDFPAELVIAMFYQGSRE
VVNLILDSDSSLDKNKIIADGFQILWRGLAKV
>Mature_192_residues
MKEHVKDKKTAIMGAALKLFTERGFHGTSTAQISKNAGVATGTLFNYFPTKEDLINSLYFEVKGNLGHSMGVGLEAETTF
QDKLKRIWSNLVNWGVNNQEEFLFVGQFCSSPYITKFTRDEVMKEYVFLHNFVDEGIKTGEVRDFPAELVIAMFYQGSRE
VVNLILDSDSSLDKNKIIADGFQILWRGLAKV

Specific function: Negatively controls the expression of the cytochrome p450BM-3 gene at the transcriptional level [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21691; Mature: 21691

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEHVKDKKTAIMGAALKLFTERGFHGTSTAQISKNAGVATGTLFNYFPTKEDLINSLYF
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCEECHHHHCCCCHHHHHHHHHH
EVKGNLGHSMGVGLEAETTFQDKLKRIWSNLVNWGVNNQEEFLFVGQFCSSPYITKFTRD
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEHHHCCCCCCHHHHH
EVMKEYVFLHNFVDEGIKTGEVRDFPAELVIAMFYQGSREVVNLILDSDSSLDKNKIIAD
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHH
GFQILWRGLAKV
HHHHHHHHHHCC
>Mature Secondary Structure
MKEHVKDKKTAIMGAALKLFTERGFHGTSTAQISKNAGVATGTLFNYFPTKEDLINSLYF
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCEECHHHHCCCCHHHHHHHHHH
EVKGNLGHSMGVGLEAETTFQDKLKRIWSNLVNWGVNNQEEFLFVGQFCSSPYITKFTRD
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEHHHCCCCCCHHHHH
EVMKEYVFLHNFVDEGIKTGEVRDFPAELVIAMFYQGSREVVNLILDSDSSLDKNKIIAD
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHH
GFQILWRGLAKV
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1544926; 2544578; 8428974 [H]