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The map label for this gene is 21227695

Identifier: 21227695

GI number: 21227695

Start: 1897334

End: 1898344

Strand: Direct

Name: 21227695

Synonym: MM_1593

Alternate gene names: NA

Gene position: 1897334-1898344 (Clockwise)

Preceding gene: 21227694

Following gene: 21227696

Centisome position: 46.32

GC content: 46.98

Gene sequence:

>1011_bases
TTGAAAGTCAATACCTGGTTTGGTGTCCTTGAGCTGGACAGTAACGGAAAAACTCTTTCCTCCGAGGTTTTTCCAAAGGA
TATAAGAGAGCTTGCTCTTCGTTCGCTTTCTCTCAGGGAGAGCAGGCAAAACCTGCCTCCTGAAGGGTTTGACCTGAAAA
CTGCAGCCCTGGAGTGCGGATTCACAGAATCCCTTTCTGAATACTATTCTCTTTTACACAAAGTAACTCTGGAAACCGTA
AAACTTCAGGTCTCACAGGCACTCACCCCTGACCAGCGCATAATTCAGGCAGTAGAAGCCCTGGATGACATTAATGAAAC
GACCAATTCCCTTTCTGAAAGGCTTTTTGAATGGTACGGAGGTTATTTTCCCGAAAGCGGGTTAAGCGGGGAAGAGCTTG
CGGTTTTTATAAGCAGGTACGGGTCTCGCGAGAATCTACCTCCTGAAGACCCTCATTATTTGAAGGCAAAAAATTCCATG
GGTGCAAAACTCGAAGCCGCAGATGAAGTTCTTCTTAAAGGTCTTGCAGAGAGTGTGTGCAGCCTCTACGAACGCCGGAA
ACAGATTGAAGCGTATATTGAAAGCAGCATGGAAATTCTTGCACCCAATCTGGCATTGCTTGCAGGACCCATGCTGGGTG
CAAGGCTGATAAGCATTGCAGGCAGTCTTGAAAAACTGGCAGCTTTTCCTTCAAGTACCATTCAGGTAATAGGGGCAAGT
AAAGCCCTCTTCAAGCACCTGCGTTCCAGGGCTCCATCCCCCAAGCATGGAATTATTTACAGCCATCCCCTCATCAATAC
ATCTCCCTGGTGGGTAAGGGGAAAAGTCGCAAGAGCCCTTGCAGCAAAGCTCTCTCTTGCCGCAAGAATTGATTTTTATT
CTGCAAAAAGGAACCCTTCACTTGAAAATGAACTGGAAGAAAAGATCCGGAAGATCAGGGCTGAAAACCCCAGACCTCCC
CAGAAGCGGCAGGAAATCAGGGCAAAGCCAAAAAAGAAGAGGAGAAAATAA

Upstream 100 bases:

>100_bases
TCCAGAAAGAGGTCCAGCGTATGCTTGACGAATCATTAGGTGGAGAAGTTCTGCTTACAAAAGGAAGGAACCGGGGCGCG
GACATCTTCGGGGGCTCTGA

Downstream 100 bases:

>100_bases
ATGCCCGAAATAAGGCAGCTTTCCGAAGGGATTTTTGAGGTTACAAAAGACAAAAAACAGCTTTCAACTCTTAACCTTGA
CCCGGGAAAAGTCGTTTACG

Product: putative RNA processing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKVNTWFGVLELDSNGKTLSSEVFPKDIRELALRSLSLRESRQNLPPEGFDLKTAALECGFTESLSEYYSLLHKVTLETV
KLQVSQALTPDQRIIQAVEALDDINETTNSLSERLFEWYGGYFPESGLSGEELAVFISRYGSRENLPPEDPHYLKAKNSM
GAKLEAADEVLLKGLAESVCSLYERRKQIEAYIESSMEILAPNLALLAGPMLGARLISIAGSLEKLAAFPSSTIQVIGAS
KALFKHLRSRAPSPKHGIIYSHPLINTSPWWVRGKVARALAAKLSLAARIDFYSAKRNPSLENELEEKIRKIRAENPRPP
QKRQEIRAKPKKKRRK

Sequences:

>Translated_336_residues
MKVNTWFGVLELDSNGKTLSSEVFPKDIRELALRSLSLRESRQNLPPEGFDLKTAALECGFTESLSEYYSLLHKVTLETV
KLQVSQALTPDQRIIQAVEALDDINETTNSLSERLFEWYGGYFPESGLSGEELAVFISRYGSRENLPPEDPHYLKAKNSM
GAKLEAADEVLLKGLAESVCSLYERRKQIEAYIESSMEILAPNLALLAGPMLGARLISIAGSLEKLAAFPSSTIQVIGAS
KALFKHLRSRAPSPKHGIIYSHPLINTSPWWVRGKVARALAAKLSLAARIDFYSAKRNPSLENELEEKIRKIRAENPRPP
QKRQEIRAKPKKKRRK
>Mature_336_residues
MKVNTWFGVLELDSNGKTLSSEVFPKDIRELALRSLSLRESRQNLPPEGFDLKTAALECGFTESLSEYYSLLHKVTLETV
KLQVSQALTPDQRIIQAVEALDDINETTNSLSERLFEWYGGYFPESGLSGEELAVFISRYGSRENLPPEDPHYLKAKNSM
GAKLEAADEVLLKGLAESVCSLYERRKQIEAYIESSMEILAPNLALLAGPMLGARLISIAGSLEKLAAFPSSTIQVIGAS
KALFKHLRSRAPSPKHGIIYSHPLINTSPWWVRGKVARALAAKLSLAARIDFYSAKRNPSLENELEEKIRKIRAENPRPP
QKRQEIRAKPKKKRRK

Specific function: Unknown

COG id: COG1498

COG function: function code J; Protein implicated in ribosomal biogenesis, Nop56p homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Nop domain [H]

Homologues:

Organism=Homo sapiens, GI32483374, Length=245, Percent_Identity=35.1020408163265, Blast_Score=144, Evalue=8e-35,
Organism=Homo sapiens, GI7706254, Length=300, Percent_Identity=33.6666666666667, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI221136939, Length=139, Percent_Identity=32.3741007194245, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17509449, Length=281, Percent_Identity=39.1459074733096, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17562296, Length=246, Percent_Identity=35.7723577235772, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17510923, Length=133, Percent_Identity=35.3383458646617, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324886, Length=258, Percent_Identity=35.2713178294574, Blast_Score=143, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6323226, Length=243, Percent_Identity=34.9794238683128, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321528, Length=139, Percent_Identity=33.8129496402878, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28572126, Length=322, Percent_Identity=31.9875776397516, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI17137636, Length=264, Percent_Identity=34.469696969697, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21357435, Length=138, Percent_Identity=32.6086956521739, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012976
- InterPro:   IPR002687 [H]

Pfam domain/function: PF01798 Nop; PF08060 NOSIC [H]

EC number: NA

Molecular weight: Translated: 37645; Mature: 37645

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVNTWFGVLELDSNGKTLSSEVFPKDIRELALRSLSLRESRQNLPPEGFDLKTAALECG
CCCCCEEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC
FTESLSEYYSLLHKVTLETVKLQVSQALTPDQRIIQAVEALDDINETTNSLSERLFEWYG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYFPESGLSGEELAVFISRYGSRENLPPEDPHYLKAKNSMGAKLEAADEVLLKGLAESVC
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHH
SLYERRKQIEAYIESSMEILAPNLALLAGPMLGARLISIAGSLEKLAAFPSSTIQVIGAS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCH
KALFKHLRSRAPSPKHGIIYSHPLINTSPWWVRGKVARALAAKLSLAARIDFYSAKRNPS
HHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LENELEEKIRKIRAENPRPPQKRQEIRAKPKKKRRK
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MKVNTWFGVLELDSNGKTLSSEVFPKDIRELALRSLSLRESRQNLPPEGFDLKTAALECG
CCCCCEEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC
FTESLSEYYSLLHKVTLETVKLQVSQALTPDQRIIQAVEALDDINETTNSLSERLFEWYG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYFPESGLSGEELAVFISRYGSRENLPPEDPHYLKAKNSMGAKLEAADEVLLKGLAESVC
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHH
SLYERRKQIEAYIESSMEILAPNLALLAGPMLGARLISIAGSLEKLAAFPSSTIQVIGAS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCH
KALFKHLRSRAPSPKHGIIYSHPLINTSPWWVRGKVARALAAKLSLAARIDFYSAKRNPS
HHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LENELEEKIRKIRAENPRPPQKRQEIRAKPKKKRRK
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]