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The map label for this gene is fmdF [H]

Identifier: 21227667

GI number: 21227667

Start: 1864505

End: 1865545

Strand: Direct

Name: fmdF [H]

Synonym: MM_1565

Alternate gene names: 21227667

Gene position: 1864505-1865545 (Clockwise)

Preceding gene: 21227666

Following gene: 21227668

Centisome position: 45.52

GC content: 49.86

Gene sequence:

>1041_bases
ATGCAAAATGAGATGCGATTGTCAGTCTTTTCCGAAAAAAAAGACCGGCAGCTGGTCTATCAGCCTGAAAAATGCATTGG
CTGCGGGACCTGTGTACAGGCATGTCCCAAAGGCACCCTTTCCATAGGGGCTGTGGGAGCTGTAGCTAGAGGGTTACTGG
ATGCGGATTTCCTGGAAATGGCAAAGAGTGAAGACTGCCTTGTCTGCGGGATCTGCGCAAAAGTCTGCCCCACAGGTGCT
CTTGAACTGAGACAGGAAGGAAAACCCCTCACAGACATGTCCTATATTTCAAGGGCTATGAGGCCGACATCAGTAAACGA
AAGCTGTGTCCACTGTGGTCTCTGTGAAGATATCTGCTCACAGGGCTGTATTGAAGTGACCCGGGAAATTTCTACGGACG
GGAAACTGAAGGTTATCGGAAAAACCCATATTGATACGGAATGCTGTGTCCATTGCGGCTGGTGTGCTGCAGTATGCCCT
GTAAATGCTATTTCTGTGGAAAAGCCCTTTGAAGGACGCTGGTCCAGGGATGAGAATGTCTGCCAGACCTGCCATACCTG
TATTGATGTCTGTCCTGCAAATGCAATTTTCAATAAGAAGGCAAAGTCCGGGGAAAGAGTTGAAAAGATCACCCACCGGC
CGGATGCCTGCATTTACTGTGGTGCATGCGCAGTTGCCTGCCCTGTTGATGCCATTGACGTCAGAAAAACTGCAATTCTG
CCGGAAATGGAGAAAAAGGGCCCCCTGGAGAAAAAGCTGATTGAAGTCCCTGCCCCCGAAGATGCGCTTCGCACCCAACT
TGAAACTGATGATGATGCGTGCCTTGGCTGCGGGAACTGTGTGATTGTCTGCCCTGTAAACGCATTCGACAACCGTGAAC
TTGCTGCAGGCTACCTGTACGACATGGACGAAAAAGCTATTCTTGGGGTTAAGAACGGAAAAATTTCGGTCGTAAACCAG
GAACGCTGCGGAGGAGATGGGACCTGTGCCCTTATCTGCCCTGTTGATGCGATAAGGCTTGTGAAAAAAGAGGTGGAATA
A

Upstream 100 bases:

>100_bases
GCGGATCCAGTGCTGCAAAAAATGTGGTGAGATGTTCGTTCAACATGATGATGAGCTGCTGTGCGGCGGATGCACAGAAT
AACGTTGAGAGGTAAATAAA

Downstream 100 bases:

>100_bases
ATGGCAGGAACAATTGCAATCAAGAACGGATACGTCTTTGACCCCCTCAACGAAATAAACGGGGAAAAAATGGATATCTT
CATCAGGGACGGAAAAGTCG

Product: molybdenum formylmethanofuran dehydrogenase subunit

Products: CO2; methanofuran; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MQNEMRLSVFSEKKDRQLVYQPEKCIGCGTCVQACPKGTLSIGAVGAVARGLLDADFLEMAKSEDCLVCGICAKVCPTGA
LELRQEGKPLTDMSYISRAMRPTSVNESCVHCGLCEDICSQGCIEVTREISTDGKLKVIGKTHIDTECCVHCGWCAAVCP
VNAISVEKPFEGRWSRDENVCQTCHTCIDVCPANAIFNKKAKSGERVEKITHRPDACIYCGACAVACPVDAIDVRKTAIL
PEMEKKGPLEKKLIEVPAPEDALRTQLETDDDACLGCGNCVIVCPVNAFDNRELAAGYLYDMDEKAILGVKNGKISVVNQ
ERCGGDGTCALICPVDAIRLVKKEVE

Sequences:

>Translated_346_residues
MQNEMRLSVFSEKKDRQLVYQPEKCIGCGTCVQACPKGTLSIGAVGAVARGLLDADFLEMAKSEDCLVCGICAKVCPTGA
LELRQEGKPLTDMSYISRAMRPTSVNESCVHCGLCEDICSQGCIEVTREISTDGKLKVIGKTHIDTECCVHCGWCAAVCP
VNAISVEKPFEGRWSRDENVCQTCHTCIDVCPANAIFNKKAKSGERVEKITHRPDACIYCGACAVACPVDAIDVRKTAIL
PEMEKKGPLEKKLIEVPAPEDALRTQLETDDDACLGCGNCVIVCPVNAFDNRELAAGYLYDMDEKAILGVKNGKISVVNQ
ERCGGDGTCALICPVDAIRLVKKEVE
>Mature_346_residues
MQNEMRLSVFSEKKDRQLVYQPEKCIGCGTCVQACPKGTLSIGAVGAVARGLLDADFLEMAKSEDCLVCGICAKVCPTGA
LELRQEGKPLTDMSYISRAMRPTSVNESCVHCGLCEDICSQGCIEVTREISTDGKLKVIGKTHIDTECCVHCGWCAAVCP
VNAISVEKPFEGRWSRDENVCQTCHTCIDVCPANAIFNKKAKSGERVEKITHRPDACIYCGACAVACPVDAIDVRKTAIL
PEMEKKGPLEKKLIEVPAPEDALRTQLETDDDACLGCGNCVIVCPVNAFDNRELAAGYLYDMDEKAILGVKNGKISVVNQ
ERCGGDGTCALICPVDAIRLVKKEVE

Specific function: Probable Electron Transfer Protein For Hydrogenase 3 [C]

COG id: COG1145

COG function: function code C; Ferredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 8 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR016459 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: 1.2.99.5

Molecular weight: Translated: 37381; Mature: 37381

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00198 4FE4S_FERREDOXIN ; PS00995 TCP1_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

9.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
11.6 %Cys+Met (Translated Protein)
9.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
11.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNEMRLSVFSEKKDRQLVYQPEKCIGCGTCVQACPKGTLSIGAVGAVARGLLDADFLEM
CCCCEEEEEECCCCCCCEEECCHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
AKSEDCLVCGICAKVCPTGALELRQEGKPLTDMSYISRAMRPTSVNESCVHCGLCEDICS
HCCCCCEEEECHHHHCCCCHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHCCHHHHHHC
QGCIEVTREISTDGKLKVIGKTHIDTECCVHCGWCAAVCPVNAISVEKPFEGRWSRDENV
CCHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCHHHHHCCCCEEECCCCCCCCCCCCHHH
CQTCHTCIDVCPANAIFNKKAKSGERVEKITHRPDACIYCGACAVACPVDAIDVRKTAIL
HHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHCCCCCEEEECCHHHHCCCCHHHHHHHHHC
PEMEKKGPLEKKLIEVPAPEDALRTQLETDDDACLGCGNCVIVCPVNAFDNRELAAGYLY
CCHHHCCCHHHHHEECCCCHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHEE
DMDEKAILGVKNGKISVVNQERCGGDGTCALICPVDAIRLVKKEVE
ECCCCEEEEECCCEEEEEEHHCCCCCCCEEEEECHHHHHHHHHHCC
>Mature Secondary Structure
MQNEMRLSVFSEKKDRQLVYQPEKCIGCGTCVQACPKGTLSIGAVGAVARGLLDADFLEM
CCCCEEEEEECCCCCCCEEECCHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
AKSEDCLVCGICAKVCPTGALELRQEGKPLTDMSYISRAMRPTSVNESCVHCGLCEDICS
HCCCCCEEEECHHHHCCCCHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHCCHHHHHHC
QGCIEVTREISTDGKLKVIGKTHIDTECCVHCGWCAAVCPVNAISVEKPFEGRWSRDENV
CCHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCHHHHHCCCCEEECCCCCCCCCCCCHHH
CQTCHTCIDVCPANAIFNKKAKSGERVEKITHRPDACIYCGACAVACPVDAIDVRKTAIL
HHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHCCCCCEEEECCHHHHCCCCHHHHHHHHHC
PEMEKKGPLEKKLIEVPAPEDALRTQLETDDDACLGCGNCVIVCPVNAFDNRELAAGYLY
CCHHHCCCHHHHHEECCCCHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHEE
DMDEKAILGVKNGKISVVNQERCGGDGTCALICPVDAIRLVKKEVE
ECCCCEEEEECCCEEEEEEHHCCCCCCCEEEEECHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formylmethanofuran; H2O; acceptor

Specific reaction: formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]