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The map label for this gene is fmdA [H]

Identifier: 21227668

GI number: 21227668

Start: 1865546

End: 1867300

Strand: Direct

Name: fmdA [H]

Synonym: MM_1566

Alternate gene names: 21227668

Gene position: 1865546-1867300 (Clockwise)

Preceding gene: 21227667

Following gene: 21227669

Centisome position: 45.54

GC content: 49.29

Gene sequence:

>1755_bases
ATGGCAGGAACAATTGCAATCAAGAACGGATACGTCTTTGACCCCCTCAACGAAATAAACGGGGAAAAAATGGATATCTT
CATCAGGGACGGAAAAGTCGTAAAAGAGCTTTCTGCATCTGAGATGAAAACTTCCAGGGTAATTGACGCCTCCGGAATGA
CTGTTATGCCAGGAGGTGTTGACTCCCATTCTCACGTTGCCGGTGCAAAGGTTAATGCCGGCAGGTCGATGCGCCCTGAA
GACCATTATAAAGCAAACCTTAAGAAAACTCCCCTCACCCATTCCGGTTCAGGCTATACAGTTCCTTCTGTTTACAAACA
GGGATATGATTACGCAGCAATGGGTTACACAACTGTTTTTGAAGCTGCAGTTCCTCCTCTTGAAGCCCGCCACACCCATG
AAGAGATGCGTGCAACTCCTCTTCTTGACATGGGAGGGTACCTTGTTCTCGGAAACAACTTTTTCCTTATGCGCTACCTC
AGGGACGGGGATATGGAAAAGGCGGCTGCTTATGTTGCCTGGATGATGAAGACCCATAAGACCTACGGGATCAAATGCGT
CAACCCCGCAGGAGTCGAAAACTGGGCATGGGGTAAAAACGTCAGCACTCTTGACGAAACCAACATCCATTTCGAAATTA
CTCCCAGAGAAGTCATTAAGGGGCTTACTGAGGTTAACGAGACCCTCGGCATGCCTATGCCAGTCCACCTGCATGCGAAC
AACCTGGGTCATCCTGGCTGTTATGCAATTACCAAGGATTCCCTCAAAATCCCTGATGGGGTAAAGACAAAACAGAACAT
GGCTGTGGAGTGGGCAGAAACCAAAATGGACCTTTCAAGGGACCGTTCGGTATACCTTACCCACCTGATGTTCAACAGTT
TTGCAGGCACGACCTGGGGGGACTGCGAGTCCGGTGTTAAGGATATTGCAGATTATATCAACAACAAAGATCATGTGGTA
ATCGACAGCGGATGCACTCCCTTCGGAGAAGCAACAGTTATGACCGGAGACGGGCCTGCCATTCATGACCTTTACACCCT
TACAGGAAATAAGTGGTCGAACACTGATGTTGAAATGGAATGCGGCTCAGGTGTCCTTCCCTTTACCTACCTCAAGTCCA
ACCCTGTGCACAGTTTGCAGTGGGCAATGGGGCTTGAATGTCTCCTGCTTATCAAAGACCCATGGAAAACTATCATGACC
ACGGACAGCCCGAATGGTGGGCCGTTTACGAAATACCCTGAGGTTATGACCTGGATCATGTCCGAGGCTTTCAGGAAACA
GACCTTCAGTGAGTGCCACAAGTGGGCAAACGATAGGAGCGAGCTGGGAGGCATAAACCGTGAGCTTTCTCTCTACGACC
TGGCGATTCTGACCAGGGCTAACCCTGCAAAGACAATCGGCATGGCCCACAGAAAAGGCTCTCTTGGTGTGGGTGCGGAC
GGAGATGTTACAGTCTACAACATAAACCCTCAGCAGCTTGACGCAAACAATTACGAAGCCCTCCTCAGGACCTTCAGGAA
GGCGGAATATACTGTGAAGGGCGGCGAAATAGTGGCTGTTAAAGGGGAGATCGTTTCCCTGCCTGAGAAGAGGACTTACT
ATTCCGAAGTGCATGTTGAAAATGAGCGGGAAAAGGAAATGCTGGTTGACGTGAAGGAGTGGTTCAGGTACTACACTCTT
GGTTTTGCCAACTACTCGACTCCAGAGAAATATCTGGCAAACCCGACTCCCATACAGGTTAACAGTGAGAGGTGA

Upstream 100 bases:

>100_bases
AATTTCGGTCGTAAACCAGGAACGCTGCGGAGGAGATGGGACCTGTGCCCTTATCTGCCCTGTTGATGCGATAAGGCTTG
TGAAAAAAGAGGTGGAATAA

Downstream 100 bases:

>100_bases
AGTGATGACAGAGGGAGTACTTGTTCAGAAAAAAACCAATGCCGGTGAAAGTTCCGGAGAAATGGAAGAAGTAACGCTTA
TTCCTAAAAAAGCGATTGAC

Product: molybdenum formylmethanofuran dehydrogenase subunit

Products: CO2; methanofuran; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MAGTIAIKNGYVFDPLNEINGEKMDIFIRDGKVVKELSASEMKTSRVIDASGMTVMPGGVDSHSHVAGAKVNAGRSMRPE
DHYKANLKKTPLTHSGSGYTVPSVYKQGYDYAAMGYTTVFEAAVPPLEARHTHEEMRATPLLDMGGYLVLGNNFFLMRYL
RDGDMEKAAAYVAWMMKTHKTYGIKCVNPAGVENWAWGKNVSTLDETNIHFEITPREVIKGLTEVNETLGMPMPVHLHAN
NLGHPGCYAITKDSLKIPDGVKTKQNMAVEWAETKMDLSRDRSVYLTHLMFNSFAGTTWGDCESGVKDIADYINNKDHVV
IDSGCTPFGEATVMTGDGPAIHDLYTLTGNKWSNTDVEMECGSGVLPFTYLKSNPVHSLQWAMGLECLLLIKDPWKTIMT
TDSPNGGPFTKYPEVMTWIMSEAFRKQTFSECHKWANDRSELGGINRELSLYDLAILTRANPAKTIGMAHRKGSLGVGAD
GDVTVYNINPQQLDANNYEALLRTFRKAEYTVKGGEIVAVKGEIVSLPEKRTYYSEVHVENEREKEMLVDVKEWFRYYTL
GFANYSTPEKYLANPTPIQVNSER

Sequences:

>Translated_584_residues
MAGTIAIKNGYVFDPLNEINGEKMDIFIRDGKVVKELSASEMKTSRVIDASGMTVMPGGVDSHSHVAGAKVNAGRSMRPE
DHYKANLKKTPLTHSGSGYTVPSVYKQGYDYAAMGYTTVFEAAVPPLEARHTHEEMRATPLLDMGGYLVLGNNFFLMRYL
RDGDMEKAAAYVAWMMKTHKTYGIKCVNPAGVENWAWGKNVSTLDETNIHFEITPREVIKGLTEVNETLGMPMPVHLHAN
NLGHPGCYAITKDSLKIPDGVKTKQNMAVEWAETKMDLSRDRSVYLTHLMFNSFAGTTWGDCESGVKDIADYINNKDHVV
IDSGCTPFGEATVMTGDGPAIHDLYTLTGNKWSNTDVEMECGSGVLPFTYLKSNPVHSLQWAMGLECLLLIKDPWKTIMT
TDSPNGGPFTKYPEVMTWIMSEAFRKQTFSECHKWANDRSELGGINRELSLYDLAILTRANPAKTIGMAHRKGSLGVGAD
GDVTVYNINPQQLDANNYEALLRTFRKAEYTVKGGEIVAVKGEIVSLPEKRTYYSEVHVENEREKEMLVDVKEWFRYYTL
GFANYSTPEKYLANPTPIQVNSER
>Mature_583_residues
AGTIAIKNGYVFDPLNEINGEKMDIFIRDGKVVKELSASEMKTSRVIDASGMTVMPGGVDSHSHVAGAKVNAGRSMRPED
HYKANLKKTPLTHSGSGYTVPSVYKQGYDYAAMGYTTVFEAAVPPLEARHTHEEMRATPLLDMGGYLVLGNNFFLMRYLR
DGDMEKAAAYVAWMMKTHKTYGIKCVNPAGVENWAWGKNVSTLDETNIHFEITPREVIKGLTEVNETLGMPMPVHLHANN
LGHPGCYAITKDSLKIPDGVKTKQNMAVEWAETKMDLSRDRSVYLTHLMFNSFAGTTWGDCESGVKDIADYINNKDHVVI
DSGCTPFGEATVMTGDGPAIHDLYTLTGNKWSNTDVEMECGSGVLPFTYLKSNPVHSLQWAMGLECLLLIKDPWKTIMTT
DSPNGGPFTKYPEVMTWIMSEAFRKQTFSECHKWANDRSELGGINRELSLYDLAILTRANPAKTIGMAHRKGSLGVGADG
DVTVYNINPQQLDANNYEALLRTFRKAEYTVKGGEIVAVKGEIVSLPEKRTYYSEVHVENEREKEMLVDVKEWFRYYTLG
FANYSTPEKYLANPTPIQVNSER

Specific function: Unknown

COG id: COG1229

COG function: function code C; Formylmethanofuran dehydrogenase subunit A

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR012027
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: 1.2.99.5

Molecular weight: Translated: 65095; Mature: 64963

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGTIAIKNGYVFDPLNEINGEKMDIFIRDGKVVKELSASEMKTSRVIDASGMTVMPGGV
CCCEEEEECCEEECCHHHCCCCEEEEEEECCHHHHHHHHHHHHHHEEEECCCCEEECCCC
DSHSHVAGAKVNAGRSMRPEDHYKANLKKTPLTHSGSGYTVPSVYKQGYDYAAMGYTTVF
CCCCCCCCCEECCCCCCCCCHHHHCCCCCCCCEECCCCCCCHHHHHCCCCEEEHHHHHHH
EAAVPPLEARHTHEEMRATPLLDMGGYLVLGNNFFLMRYLRDGDMEKAAAYVAWMMKTHK
HHCCCCCHHHHCHHHHHCCCEECCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHCC
TYGIKCVNPAGVENWAWGKNVSTLDETNIHFEITPREVIKGLTEVNETLGMPMPVHLHAN
CCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCEEEEEECC
NLGHPGCYAITKDSLKIPDGVKTKQNMAVEWAETKMDLSRDRSVYLTHLMFNSFAGTTWG
CCCCCCEEEEECCCEECCCCCCCCCCCEEEEHHHHHHHCCCCCEEEEEHHHHHCCCCCCC
DCESGVKDIADYINNKDHVVIDSGCTPFGEATVMTGDGPAIHDLYTLTGNKWSNTDVEME
CHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCEEEE
CGSGVLPFTYLKSNPVHSLQWAMGLECLLLIKDPWKTIMTTDSPNGGPFTKYPEVMTWIM
CCCCCCCEEEECCCCCHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHH
SEAFRKQTFSECHKWANDRSELGGINRELSLYDLAILTRANPAKTIGMAHRKGSLGVGAD
HHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHCCCCCCCCCCC
GDVTVYNINPQQLDANNYEALLRTFRKAEYTVKGGEIVAVKGEIVSLPEKRTYYSEVHVE
CCEEEEECCHHHCCCCCHHHHHHHHHHCCEEECCCEEEEECCCEEECCCCCCEEEEEEEC
NEREKEMLVDVKEWFRYYTLGFANYSTPEKYLANPTPIQVNSER
CCHHHHHHHHHHHHHHHHHEECCCCCCCHHHCCCCCCEEECCCC
>Mature Secondary Structure 
AGTIAIKNGYVFDPLNEINGEKMDIFIRDGKVVKELSASEMKTSRVIDASGMTVMPGGV
CCEEEEECCEEECCHHHCCCCEEEEEEECCHHHHHHHHHHHHHHEEEECCCCEEECCCC
DSHSHVAGAKVNAGRSMRPEDHYKANLKKTPLTHSGSGYTVPSVYKQGYDYAAMGYTTVF
CCCCCCCCCEECCCCCCCCCHHHHCCCCCCCCEECCCCCCCHHHHHCCCCEEEHHHHHHH
EAAVPPLEARHTHEEMRATPLLDMGGYLVLGNNFFLMRYLRDGDMEKAAAYVAWMMKTHK
HHCCCCCHHHHCHHHHHCCCEECCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHCC
TYGIKCVNPAGVENWAWGKNVSTLDETNIHFEITPREVIKGLTEVNETLGMPMPVHLHAN
CCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCEEEEEECC
NLGHPGCYAITKDSLKIPDGVKTKQNMAVEWAETKMDLSRDRSVYLTHLMFNSFAGTTWG
CCCCCCEEEEECCCEECCCCCCCCCCCEEEEHHHHHHHCCCCCEEEEEHHHHHCCCCCCC
DCESGVKDIADYINNKDHVVIDSGCTPFGEATVMTGDGPAIHDLYTLTGNKWSNTDVEME
CHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCEEEE
CGSGVLPFTYLKSNPVHSLQWAMGLECLLLIKDPWKTIMTTDSPNGGPFTKYPEVMTWIM
CCCCCCCEEEECCCCCHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHH
SEAFRKQTFSECHKWANDRSELGGINRELSLYDLAILTRANPAKTIGMAHRKGSLGVGAD
HHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHCCCCCCCCCCC
GDVTVYNINPQQLDANNYEALLRTFRKAEYTVKGGEIVAVKGEIVSLPEKRTYYSEVHVE
CCEEEEECCHHHCCCCCHHHHHHHHHHCCEEECCCEEEEECCCEEECCCCCCEEEEEEEC
NEREKEMLVDVKEWFRYYTLGFANYSTPEKYLANPTPIQVNSER
CCHHHHHHHHHHHHHHHHHEECCCCCCCHHHCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formylmethanofuran; H2O; acceptor

Specific reaction: formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]