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The map label for this gene is mtrC

Identifier: 21227647

GI number: 21227647

Start: 1842514

End: 1843317

Strand: Reverse

Name: mtrC

Synonym: MM_1545

Alternate gene names: 21227647

Gene position: 1843317-1842514 (Counterclockwise)

Preceding gene: 21227648

Following gene: 21227646

Centisome position: 45.0

GC content: 47.64

Gene sequence:

>804_bases
ATGTCTGCAGGTGGAGCAGGAGGAGAAGCTAAAGGTGCATACCCTCAACAGACACTAATGGCCCTGGGTATAGTCGGCGG
TCTTGTCGGAATTTACCTTGGTCACTTCATGCCTCCGGCGTATTCCTTCTTCGGAGGAATTGGAGCAATCTGTGCAACAG
TCTGGGGTGCTGATGCTGTCAGGCGTGTTGCAAGCTATGGACTTGGTACCGGTGTCCCATCAATTGGTATGCTGGCTCTA
GGTATGGGTATTCTTGCAGCTCTCTTCGGACTTGCCCTGGGAGGCATTGCGGGACCCATATTAGCCGTCGTTGTAGCAGC
AATTATTGGTGGCGTTATTGGCGCTCTTGCAAACAAAGTAATCGGAATGGGTATCCCAATAATGGAACAGGCAATGATAG
AGATTTCATGCGCAGGCACCCTTGTAATTCTCGGTCTGAGTGTCGTCATTGCAGGATCCTTTGATTATGCTGCAATCATA
GAAAATGTGATCGCAAACGGATACATTGCACTGATCTTTATAATAGGCGGTATGGGAATCCTTCACCCCTTCAACGCATG
CCTTGGCCCAGATGAGTCACAGGACAGAACACTGATTCTTGCTGTTGAAAAAGCAGCTATTGCATTAATAATTACAGGCT
TTGCATCATCACTCCATGAAGGACTAATGACTGCTGGCATAAACATACTCGTAGGACTTGTCATCTGGTATGTTGCTTTC
AGCAAGTATTATGCACTCATTAAGAGAGATGCATATGCAGTGGTTGGAACCGGTCTGCTGCCGAGTGCGGAGGAATTGCA
ATGA

Upstream 100 bases:

>100_bases
TTCAAGAAATGGCCGAAGGCGGTTATTTCCTCCGTCGTGGCATCAATACTGTGTGCTATCGTGGCAGTAATTGCAATAGC
ACAGCTAGGAGGTATCTAAA

Downstream 100 bases:

>100_bases
GCATTGTTCGCATAGCTCCCGAGATAAATTTAGTCATGGACACAGAGTCGGGAACCGTAACTCAGGAAAGGAAAGACTCG
ATTCAGTACTCCATGGAGCC

Product: tetrahydromethanopterin S-methyltransferase subunit C

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSAGGAGGEAKGAYPQQTLMALGIVGGLVGIYLGHFMPPAYSFFGGIGAICATVWGADAVRRVASYGLGTGVPSIGMLAL
GMGILAALFGLALGGIAGPILAVVVAAIIGGVIGALANKVIGMGIPIMEQAMIEISCAGTLVILGLSVVIAGSFDYAAII
ENVIANGYIALIFIIGGMGILHPFNACLGPDESQDRTLILAVEKAAIALIITGFASSLHEGLMTAGINILVGLVIWYVAF
SKYYALIKRDAYAVVGTGLLPSAEELQ

Sequences:

>Translated_267_residues
MSAGGAGGEAKGAYPQQTLMALGIVGGLVGIYLGHFMPPAYSFFGGIGAICATVWGADAVRRVASYGLGTGVPSIGMLAL
GMGILAALFGLALGGIAGPILAVVVAAIIGGVIGALANKVIGMGIPIMEQAMIEISCAGTLVILGLSVVIAGSFDYAAII
ENVIANGYIALIFIIGGMGILHPFNACLGPDESQDRTLILAVEKAAIALIITGFASSLHEGLMTAGINILVGLVIWYVAF
SKYYALIKRDAYAVVGTGLLPSAEELQ
>Mature_266_residues
SAGGAGGEAKGAYPQQTLMALGIVGGLVGIYLGHFMPPAYSFFGGIGAICATVWGADAVRRVASYGLGTGVPSIGMLALG
MGILAALFGLALGGIAGPILAVVVAAIIGGVIGALANKVIGMGIPIMEQAMIEISCAGTLVILGLSVVIAGSFDYAAIIE
NVIANGYIALIFIIGGMGILHPFNACLGPDESQDRTLILAVEKAAIALIITGFASSLHEGLMTAGINILVGLVIWYVAFS
KYYALIKRDAYAVVGTGLLPSAEELQ

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step

COG id: COG4061

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit C

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mtrC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTRC_METMA (O59638)

Other databases:

- EMBL:   AF042381
- EMBL:   AE008384
- RefSeq:   NP_633569.1
- GeneID:   1479887
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_1545
- NMPDR:   fig|192952.1.peg.1545
- HOGENOM:   HBG542041
- OMA:   ILHPFNA
- ProtClustDB:   PRK01030
- BioCyc:   MMAZ192952:MM1545-MONOMER
- BRENDA:   2.1.1.86
- GO:   GO:0015948
- HAMAP:   MF_01096
- InterPro:   IPR005865
- PIRSF:   PIRSF006530
- ProDom:   PD013899
- TIGRFAMs:   TIGR01148

Pfam domain/function: PF04211 MtrC

EC number: =2.1.1.86

Molecular weight: Translated: 26942; Mature: 26811

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc3c2668)-; HASH(0xefbb4fc)-; HASH(0xf0113d8)-; HASH(0xea9f60c)-; HASH(0xe895adc)-; HASH(0xeef0a10)-; HASH(0xdf34624)-; HASH(0xd6d8318)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGGAGGEAKGAYPQQTLMALGIVGGLVGIYLGHFMPPAYSFFGGIGAICATVWGADAV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RRVASYGLGTGVPSIGMLALGMGILAALFGLALGGIAGPILAVVVAAIIGGVIGALANKV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGMGIPIMEQAMIEISCAGTLVILGLSVVIAGSFDYAAIIENVIANGYIALIFIIGGMGI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCHHH
LHPFNACLGPDESQDRTLILAVEKAAIALIITGFASSLHEGLMTAGINILVGLVIWYVAF
HHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKYYALIKRDAYAVVGTGLLPSAEELQ
HHHHHHHHHHHHHEEECCCCCCHHHCH
>Mature Secondary Structure 
SAGGAGGEAKGAYPQQTLMALGIVGGLVGIYLGHFMPPAYSFFGGIGAICATVWGADAV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RRVASYGLGTGVPSIGMLALGMGILAALFGLALGGIAGPILAVVVAAIIGGVIGALANKV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGMGIPIMEQAMIEISCAGTLVILGLSVVIAGSFDYAAIIENVIANGYIALIFIIGGMGI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCHHH
LHPFNACLGPDESQDRTLILAVEKAAIALIITGFASSLHEGLMTAGINILVGLVIWYVAF
HHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKYYALIKRDAYAVVGTGLLPSAEELQ
HHHHHHHHHHHHHEEECCCCCCHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9559648; 12125824