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The map label for this gene is mtrB

Identifier: 21227646

GI number: 21227646

Start: 1842191

End: 1842517

Strand: Reverse

Name: mtrB

Synonym: MM_1544

Alternate gene names: 21227646

Gene position: 1842517-1842191 (Counterclockwise)

Preceding gene: 21227647

Following gene: 21227645

Centisome position: 44.98

GC content: 47.09

Gene sequence:

>327_bases
ATGAGCATTGTTCGCATAGCTCCCGAGATAAATTTAGTCATGGACACAGAGTCGGGAACCGTAACTCAGGAAAGGAAAGA
CTCGATTCAGTACTCCATGGAGCCTGTCTTTGAAAGGGTGGACAAACTGGATGCGATTGCAGACGATCTGGTGAATTCCC
TTTCACCCAGCAAACCGCTCCTTAATACATGGCCAGGACGTGAGAACACCTCCTACATAGCAGGAATTTACTCAAACTCC
TTCTACGGGATTATTGTAGGTCTTGCTTTCAGCGGACTGCTGGCCCTAATCATATACATAACAAGACTGATGGGAGGGGT
GGTGTAA

Upstream 100 bases:

>100_bases
TCATCTGGTATGTTGCTTTCAGCAAGTATTATGCACTCATTAAGAGAGATGCATATGCAGTGGTTGGAACCGGTCTGCTG
CCGAGTGCGGAGGAATTGCA

Downstream 100 bases:

>100_bases
AATGGCAGATAAAAGAGAACCAGCCCCAGGATGGCCTATCCTGAAAGGAGAATACGAAGTAGGCGATGTAAAGAACTCTG
TACTGGTAATTACCTGCGGC

Product: tetrahydromethanopterin S-methyltransferase subunit B

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit B

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MSIVRIAPEINLVMDTESGTVTQERKDSIQYSMEPVFERVDKLDAIADDLVNSLSPSKPLLNTWPGRENTSYIAGIYSNS
FYGIIVGLAFSGLLALIIYITRLMGGVV

Sequences:

>Translated_108_residues
MSIVRIAPEINLVMDTESGTVTQERKDSIQYSMEPVFERVDKLDAIADDLVNSLSPSKPLLNTWPGRENTSYIAGIYSNS
FYGIIVGLAFSGLLALIIYITRLMGGVV
>Mature_107_residues
SIVRIAPEINLVMDTESGTVTQERKDSIQYSMEPVFERVDKLDAIADDLVNSLSPSKPLLNTWPGRENTSYIAGIYSNSF
YGIIVGLAFSGLLALIIYITRLMGGVV

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step

COG id: COG4062

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit B

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mtrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTRB_METMA (P80655)

Other databases:

- EMBL:   AF042381
- EMBL:   AE008384
- RefSeq:   NP_633568.1
- GeneID:   1479886
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_1544
- NMPDR:   fig|192952.1.peg.1544
- HOGENOM:   HBG732740
- OMA:   EMRKDIL
- ProtClustDB:   PRK00965
- BioCyc:   MMAZ192952:MM1544-MONOMER
- BRENDA:   2.1.1.86
- GO:   GO:0015948
- HAMAP:   MF_01094
- InterPro:   IPR008690
- ProDom:   PD012565

Pfam domain/function: PF05440 MtrB

EC number: =2.1.1.86

Molecular weight: Translated: 11872; Mature: 11741

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xeac4180)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVRIAPEINLVMDTESGTVTQERKDSIQYSMEPVFERVDKLDAIADDLVNSLSPSKPL
CCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LNTWPGRENTSYIAGIYSNSFYGIIVGLAFSGLLALIIYITRLMGGVV
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
SIVRIAPEINLVMDTESGTVTQERKDSIQYSMEPVFERVDKLDAIADDLVNSLSPSKPL
CEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LNTWPGRENTSYIAGIYSNSFYGIIVGLAFSGLLALIIYITRLMGGVV
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9559648; 12125824; 8774736