| Definition | Methanosarcina mazei Go1 chromosome, complete genome. |
|---|---|
| Accession | NC_003901 |
| Length | 4,096,345 |
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The map label for this gene is polB [H]
Identifier: 21227447
GI number: 21227447
Start: 1609877
End: 1611820
Strand: Direct
Name: polB [H]
Synonym: MM_1345
Alternate gene names: 21227447
Gene position: 1609877-1611820 (Clockwise)
Preceding gene: 21227438
Following gene: 21227448
Centisome position: 39.3
GC content: 44.86
Gene sequence:
>1944_bases ATGAATGAAATTGATATTGTAAGGGCAGTAACAGAAGAAGGGTATCAGATAAGCCCTTCAGCAGTAGAGCTAATTAAATC AAGTATTTCCCCTGAAAGCCTTCTAAAATACGTCCTTTCAACTATTGATGACTGTATTTTTGTTATTGAATCTGAACATA TCGATCTGAAAGGTTTTGAAGCTTCGAAAAAGGCTTTTGACGCTTCTGAATCTCCCTCGCTAACACTTTCTCGAGCACAG TCAGGTAACATGTCCGCAGGAAATATGTCTTCAGGAAATAAACCTTCAGATGTCATTTCCTCCCCTTCCTCAGAACCCGT AAATTCTGATAGGTTAAATAATTCTGAAAAGGTAAAAACTCCTGGTTCTCTTTCAGACTCTCTCGAGGAAGAGGGATCAA CTTTGAGTGTTGAAACGGAAGTGGTTTCAGGGTTTGATATCCCTCACAACAATCCAGTAACAGATTCCGACATCTCTTTT TCTCAGGAGCCTGCTTCTGATATTGCTGCCCACGGTTCTCTAGCCAGTACTGTTTATCCATCTTCTGGCGGGATAGAAAA ACAGGTTTCTTCTTTTTTCGGAGAGGCCGGCTCTAAATCGTTTTCTGCTTTTAAAAGCGCTTCCAGAGCTGACTCCTTTT TCTCAAATGAAGGAGCTCTTTCTTCAAGTTCCAGAGCTGAAGGAGTCAGGCATATTTCTGGCCTTAACCCCATTACAGTG CTTTCCGACATCACCGGGCATTCAACCTGTGTCGGAGAGTATGTGCAGTTCGTGCAATACTTCAGAGATAGATACAGCAA GCTCTCTGAAATCCTCAGGGGCAGGATGAATGCACGCCCTATAGAAAGTTTGAAGAAGAGGAGTTTTAGGCGCGGATCAG ACGGCGGTAATGAGGAGCTATCCATTATAGGGATTGTTTCGGATATCAGCAGCACCAATAATGGGCACAAAATTCTTTCT CTGGAGGACTCTACAGGCTCTTTTTCAGTCCTTATCCGGAACAGCGATAAAGAACTCTACGAACTGGCTTCGCGGCTTAT TCTGGATGAGGTTATCGGAGTAACAGGCTCGGTTACAAATGACGGAAACCTTATGCTTGCTACAAAGATTCTTCAGCCTG ATGTCCCGAACAGTATACAGCACAGGACAGGAAGCCACGGAAAAGTTGTGCTTATTTCGGATGTACATGTGGGAAGTTCC CAGTTTCTTGAAGACGCCTGGCTGGATTTTCTGGATTTTTTAAAAGGAGAGTCTGATTCTGAAGAGATGAGGGAGATCGC GTCCCAGGTCCGTTATCTGGTTGTTGCAGGAGACCTTGTGGATGGAATTGGGATCTATCCTGACCAGGAAATGGAACTCG ATATTCTTGATGTTTATGAACAGTACAGGAAAGCGGCCGATTACTTTAAAGAAATTCCCAGACACATTCGTGTGATTATA AGTCCCGGAAACCATGATGCTGTACGCCAGGCAGAACCGCAGCCTGCCCTGCCTGAGAGGATCTGTGCGGACTTTCCTGA AAATGTCACATTCGTAGGCAACCCTGCTCTTGTGGACCTTGATGGAATCCGAATACTTATCTATCACGGAAGGTCGATTG ATGATCTTGTGGCAAGTGTTCCGGGAGTTTCATATCATGAGCCTGCAGGTGCAGTCCTTGAAATGCTTAAGCGCAGGCAT CTTGCTCCAACATACGGAAGCCGCGTTTCCATATCCCCGGAGAAAAAAGACTATTTTATAATTGATCCAGTTCCTGATAT TATTCACACCGGGCACGTCCATACCCTGGGAGTCCAGCGCTATAAAAATGTCCTTCTGGTCAATTCCGGAACATGGCAGG CACAAACTGAGTTCCAGAAACGTGTAAATCTCGTTCCAGTGCCGGCTCGGGTTCCAGTTGTGGATCTTGCAGATTTTGAT GTAAAGATCCTGGCATTCGATTAA
Upstream 100 bases:
>100_bases TCCCTTAATTCTTTTGACTTCAAGTTGTTGGATATAATGGAGTAAGGGTCTATTAAATTCTGACAGTCAAGAGACCAGGT CGGGTAATCAGGTCGAAATT
Downstream 100 bases:
>100_bases ATTAAGTTGACCGAATCTTTTTGATCAGGACAGGACTGAGAATTCTAATTGCTCTGCCATCTGTGTGCTCTACCTGCAGT TCTCTAAAATTATTTTCCGA
Product: DNA polymerase II small subunit
Products: NA
Alternate protein names: Pol II [H]
Number of amino acids: Translated: 647; Mature: 647
Protein sequence:
>647_residues MNEIDIVRAVTEEGYQISPSAVELIKSSISPESLLKYVLSTIDDCIFVIESEHIDLKGFEASKKAFDASESPSLTLSRAQ SGNMSAGNMSSGNKPSDVISSPSSEPVNSDRLNNSEKVKTPGSLSDSLEEEGSTLSVETEVVSGFDIPHNNPVTDSDISF SQEPASDIAAHGSLASTVYPSSGGIEKQVSSFFGEAGSKSFSAFKSASRADSFFSNEGALSSSSRAEGVRHISGLNPITV LSDITGHSTCVGEYVQFVQYFRDRYSKLSEILRGRMNARPIESLKKRSFRRGSDGGNEELSIIGIVSDISSTNNGHKILS LEDSTGSFSVLIRNSDKELYELASRLILDEVIGVTGSVTNDGNLMLATKILQPDVPNSIQHRTGSHGKVVLISDVHVGSS QFLEDAWLDFLDFLKGESDSEEMREIASQVRYLVVAGDLVDGIGIYPDQEMELDILDVYEQYRKAADYFKEIPRHIRVII SPGNHDAVRQAEPQPALPERICADFPENVTFVGNPALVDLDGIRILIYHGRSIDDLVASVPGVSYHEPAGAVLEMLKRRH LAPTYGSRVSISPEKKDYFIIDPVPDIIHTGHVHTLGVQRYKNVLLVNSGTWQAQTEFQKRVNLVPVPARVPVVDLADFD VKILAFD
Sequences:
>Translated_647_residues MNEIDIVRAVTEEGYQISPSAVELIKSSISPESLLKYVLSTIDDCIFVIESEHIDLKGFEASKKAFDASESPSLTLSRAQ SGNMSAGNMSSGNKPSDVISSPSSEPVNSDRLNNSEKVKTPGSLSDSLEEEGSTLSVETEVVSGFDIPHNNPVTDSDISF SQEPASDIAAHGSLASTVYPSSGGIEKQVSSFFGEAGSKSFSAFKSASRADSFFSNEGALSSSSRAEGVRHISGLNPITV LSDITGHSTCVGEYVQFVQYFRDRYSKLSEILRGRMNARPIESLKKRSFRRGSDGGNEELSIIGIVSDISSTNNGHKILS LEDSTGSFSVLIRNSDKELYELASRLILDEVIGVTGSVTNDGNLMLATKILQPDVPNSIQHRTGSHGKVVLISDVHVGSS QFLEDAWLDFLDFLKGESDSEEMREIASQVRYLVVAGDLVDGIGIYPDQEMELDILDVYEQYRKAADYFKEIPRHIRVII SPGNHDAVRQAEPQPALPERICADFPENVTFVGNPALVDLDGIRILIYHGRSIDDLVASVPGVSYHEPAGAVLEMLKRRH LAPTYGSRVSISPEKKDYFIIDPVPDIIHTGHVHTLGVQRYKNVLLVNSGTWQAQTEFQKRVNLVPVPARVPVVDLADFD VKILAFD >Mature_647_residues MNEIDIVRAVTEEGYQISPSAVELIKSSISPESLLKYVLSTIDDCIFVIESEHIDLKGFEASKKAFDASESPSLTLSRAQ SGNMSAGNMSSGNKPSDVISSPSSEPVNSDRLNNSEKVKTPGSLSDSLEEEGSTLSVETEVVSGFDIPHNNPVTDSDISF SQEPASDIAAHGSLASTVYPSSGGIEKQVSSFFGEAGSKSFSAFKSASRADSFFSNEGALSSSSRAEGVRHISGLNPITV LSDITGHSTCVGEYVQFVQYFRDRYSKLSEILRGRMNARPIESLKKRSFRRGSDGGNEELSIIGIVSDISSTNNGHKILS LEDSTGSFSVLIRNSDKELYELASRLILDEVIGVTGSVTNDGNLMLATKILQPDVPNSIQHRTGSHGKVVLISDVHVGSS QFLEDAWLDFLDFLKGESDSEEMREIASQVRYLVVAGDLVDGIGIYPDQEMELDILDVYEQYRKAADYFKEIPRHIRVII SPGNHDAVRQAEPQPALPERICADFPENVTFVGNPALVDLDGIRILIYHGRSIDDLVASVPGVSYHEPAGAVLEMLKRRH LAPTYGSRVSISPEKKDYFIIDPVPDIIHTGHVHTLGVQRYKNVLLVNSGTWQAQTEFQKRVNLVPVPARVPVVDLADFD VKILAFD
Specific function: Possesses two activities:a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase [H]
COG id: COG1311
COG function: function code L; Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the DNA polymerase delta/II small subunit family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004843 - InterPro: IPR012340 - InterPro: IPR004365 - InterPro: IPR011149 [H]
Pfam domain/function: PF00149 Metallophos; PF01336 tRNA_anti [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 70557; Mature: 70557
Theoretical pI: Translated: 4.68; Mature: 4.68
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 1.7 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNEIDIVRAVTEEGYQISPSAVELIKSSISPESLLKYVLSTIDDCIFVIESEHIDLKGFE CCHHHHHHHHHHCCCEECHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCC ASKKAFDASESPSLTLSRAQSGNMSAGNMSSGNKPSDVISSPSSEPVNSDRLNNSEKVKT HHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHCCCCCCCCC PGSLSDSLEEEGSTLSVETEVVSGFDIPHNNPVTDSDISFSQEPASDIAAHGSLASTVYP CCCCHHHHHHCCCEEEEEEHEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHEECC SSGGIEKQVSSFFGEAGSKSFSAFKSASRADSFFSNEGALSSSSRAEGVRHISGLNPITV CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHH LSDITGHSTCVGEYVQFVQYFRDRYSKLSEILRGRMNARPIESLKKRSFRRGSDGGNEEL HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCE SIIGIVSDISSTNNGHKILSLEDSTGSFSVLIRNSDKELYELASRLILDEVIGVTGSVTN EEEEEEECCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCC DGNLMLATKILQPDVPNSIQHRTGSHGKVVLISDVHVGSSQFLEDAWLDFLDFLKGESDS CCCEEEEEEECCCCCCCHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCH EEMREIASQVRYLVVAGDLVDGIGIYPDQEMELDILDVYEQYRKAADYFKEIPRHIRVII HHHHHHHHHHEEEEEECCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEE SPGNHDAVRQAEPQPALPERICADFPENVTFVGNPALVDLDGIRILIYHGRSIDDLVASV CCCCCCHHHCCCCCCCCHHHHHHCCCCCEEEECCCCEEEECCEEEEEEECCCHHHHHHHC PGVSYHEPAGAVLEMLKRRHLAPTYGSRVSISPEKKDYFIIDPVPDIIHTGHVHTLGVQR CCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEECCCHHHHHCCCEEEEEHHH YKNVLLVNSGTWQAQTEFQKRVNLVPVPARVPVVDLADFDVKILAFD HCCEEEEECCCCCHHHHHHHCCCEEECCCCCCEEEECCCCEEEEEEC >Mature Secondary Structure MNEIDIVRAVTEEGYQISPSAVELIKSSISPESLLKYVLSTIDDCIFVIESEHIDLKGFE CCHHHHHHHHHHCCCEECHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCC ASKKAFDASESPSLTLSRAQSGNMSAGNMSSGNKPSDVISSPSSEPVNSDRLNNSEKVKT HHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHCCCCCCCCC PGSLSDSLEEEGSTLSVETEVVSGFDIPHNNPVTDSDISFSQEPASDIAAHGSLASTVYP CCCCHHHHHHCCCEEEEEEHEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHEECC SSGGIEKQVSSFFGEAGSKSFSAFKSASRADSFFSNEGALSSSSRAEGVRHISGLNPITV CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHH LSDITGHSTCVGEYVQFVQYFRDRYSKLSEILRGRMNARPIESLKKRSFRRGSDGGNEEL HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCE SIIGIVSDISSTNNGHKILSLEDSTGSFSVLIRNSDKELYELASRLILDEVIGVTGSVTN EEEEEEECCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCC DGNLMLATKILQPDVPNSIQHRTGSHGKVVLISDVHVGSSQFLEDAWLDFLDFLKGESDS CCCEEEEEEECCCCCCCHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCH EEMREIASQVRYLVVAGDLVDGIGIYPDQEMELDILDVYEQYRKAADYFKEIPRHIRVII HHHHHHHHHHEEEEEECCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEE SPGNHDAVRQAEPQPALPERICADFPENVTFVGNPALVDLDGIRILIYHGRSIDDLVASV CCCCCCHHHCCCCCCCCHHHHHHCCCCCEEEECCCCEEEECCEEEEEEECCCHHHHHHHC PGVSYHEPAGAVLEMLKRRHLAPTYGSRVSISPEKKDYFIIDPVPDIIHTGHVHTLGVQR CCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEECCCHHHHHCCCEEEEEHHH YKNVLLVNSGTWQAQTEFQKRVNLVPVPARVPVVDLADFDVKILAFD HCCEEEEECCCCCHHHHHHHCCCEEECCCCCCEEEECCCCEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9389475 [H]