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The map label for this gene is mshA [H]

Identifier: 21227240

GI number: 21227240

Start: 1346281

End: 1347486

Strand: Direct

Name: mshA [H]

Synonym: MM_1138

Alternate gene names: 21227240

Gene position: 1346281-1347486 (Clockwise)

Preceding gene: 21227236

Following gene: 21227243

Centisome position: 32.87

GC content: 40.88

Gene sequence:

>1206_bases
ATGAGAGTACTGGAAGTATGTCAGGAGTTCCCTAACAGGTATTATCCACAGCTTGGAACATTTATAAAGCAAAGTATAGA
CTCTATCGCAAATCAGGGAGTAGAATTGACAGTTATTTCTCCAAAAGCTTTTGTACTTCCTTTTTCTGCATTTCCGTACC
ATAATTTTTCTAAATTACCCGGGATTGAGCACACGGAAAAATATGACCTTCACTTTCCGCGCTACTTCTACGCAGTCCCT
AAAAAGTACTTCTATCCTTTAACCGGCATGTCATATTCTTATTTTGTTTCCGGATATGCTATGAAAAACATAAATCCGAA
ACCGGAGCTGATTCATGCACACTTCTCATACCCTGATGGGTACGGAATGATGAAACTCGCAAAGAAATGGGAAGTTCCTC
TTGTAATCAGCGCCCTTGGCACTATAGAAAGAAAAGTTGCCTATGAAGGTTCCTATACTTCAAAACAGATTATAGAAGCC
ATGAATTTTGCCGACAGGATACTTTCTGTCAGTGAGGACCTCAAAACCCACATAGTAAACCTCGGGATAGACGAAAATAA
AGTAGATGTGGTTCCTAACGGCGTGGATACGGAAATATTCAGACCGGCAGGAAAAGAATATGCAAGAAATGTTTTAAACC
TGCCTCAGGAAAAAAAGATTGTCCTGTTTATAGGAGCCCTGAGGAAAATAAAAGGTGTGGATTATCTTATTGAAGCTGCA
AAAAGTTTTGTGAATAAAAACACAGACCTCTACATGGTAGGCAGGGATGATGGGCTTAGAAAAAGCCTGGAGAAAAGGGC
AGAAGAACTTAAAATCTCCGGCTTTATCAAATTTACAGGGCCAGTAACCCATGAAGAGATTCCCCTCTGGATTTCAGCAG
CTGATATGCTGGTTTTACCTTCCCTTTCAGAAGGGAGACCAAATGTTGTTCTTGAAGCTCTTTCCTGTGAAGTCCCTGTA
GTGGCGACTGACGTTGGCGGAATCCCGGAACTGATGGTTGAAGGGGAAACAGGCTATCTGGTACCTTCTAAAAACCCTGT
ACAGCTATCAGAGAAAATAAACAAATTACTTGAAAACGAAAGCAGAAGAGAAAAGATGGGAAAATTCGGCCGCAAAAGCA
TAATCCAGAGAGGACTTACCTGGGAATCTCATGCAAAGAAAACTGTAGATATATATTCAGAACTCCTCGCAAGATCCTCA
AAATGA

Upstream 100 bases:

>100_bases
AAAAAAGAAAAGATATGCGTTCCACAGAGAGATATTTATAGGAGAAATTCTCTCCTTTGTGTGTTTTTGAGGCATCCAAA
TAGAAAAAAGGAAAAGAATT

Downstream 100 bases:

>100_bases
ATTTACCGGAAAATTAAAGACAAAGTACAGATTTGCCCAAAAGCTCTCTCCACATACTAATATAACATCTGAGCTGTCCC
TTTAGCTCAGACAAAGCTCC

Product: glycosyltransferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MRVLEVCQEFPNRYYPQLGTFIKQSIDSIANQGVELTVISPKAFVLPFSAFPYHNFSKLPGIEHTEKYDLHFPRYFYAVP
KKYFYPLTGMSYSYFVSGYAMKNINPKPELIHAHFSYPDGYGMMKLAKKWEVPLVISALGTIERKVAYEGSYTSKQIIEA
MNFADRILSVSEDLKTHIVNLGIDENKVDVVPNGVDTEIFRPAGKEYARNVLNLPQEKKIVLFIGALRKIKGVDYLIEAA
KSFVNKNTDLYMVGRDDGLRKSLEKRAEELKISGFIKFTGPVTHEEIPLWISAADMLVLPSLSEGRPNVVLEALSCEVPV
VATDVGGIPELMVEGETGYLVPSKNPVQLSEKINKLLENESRREKMGKFGRKSIIQRGLTWESHAKKTVDIYSELLARSS
K

Sequences:

>Translated_401_residues
MRVLEVCQEFPNRYYPQLGTFIKQSIDSIANQGVELTVISPKAFVLPFSAFPYHNFSKLPGIEHTEKYDLHFPRYFYAVP
KKYFYPLTGMSYSYFVSGYAMKNINPKPELIHAHFSYPDGYGMMKLAKKWEVPLVISALGTIERKVAYEGSYTSKQIIEA
MNFADRILSVSEDLKTHIVNLGIDENKVDVVPNGVDTEIFRPAGKEYARNVLNLPQEKKIVLFIGALRKIKGVDYLIEAA
KSFVNKNTDLYMVGRDDGLRKSLEKRAEELKISGFIKFTGPVTHEEIPLWISAADMLVLPSLSEGRPNVVLEALSCEVPV
VATDVGGIPELMVEGETGYLVPSKNPVQLSEKINKLLENESRREKMGKFGRKSIIQRGLTWESHAKKTVDIYSELLARSS
K
>Mature_401_residues
MRVLEVCQEFPNRYYPQLGTFIKQSIDSIANQGVELTVISPKAFVLPFSAFPYHNFSKLPGIEHTEKYDLHFPRYFYAVP
KKYFYPLTGMSYSYFVSGYAMKNINPKPELIHAHFSYPDGYGMMKLAKKWEVPLVISALGTIERKVAYEGSYTSKQIIEA
MNFADRILSVSEDLKTHIVNLGIDENKVDVVPNGVDTEIFRPAGKEYARNVLNLPQEKKIVLFIGALRKIKGVDYLIEAA
KSFVNKNTDLYMVGRDDGLRKSLEKRAEELKISGFIKFTGPVTHEEIPLWISAADMLVLPSLSEGRPNVVLEALSCEVPV
VATDVGGIPELMVEGETGYLVPSKNPVQLSEKINKLLENESRREKMGKFGRKSIIQRGLTWESHAKKTVDIYSELLARSS
K

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI17532709, Length=236, Percent_Identity=27.1186440677966, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI9755344, Length=255, Percent_Identity=25.0980392156863, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24654571, Length=152, Percent_Identity=29.6052631578947, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 45316; Mature: 45316

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLEVCQEFPNRYYPQLGTFIKQSIDSIANQGVELTVISPKAFVLPFSAFPYHNFSKLP
CCHHHHHHHCCHHHCHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCCCCCCHHHCC
GIEHTEKYDLHFPRYFYAVPKKYFYPLTGMSYSYFVSGYAMKNINPKPELIHAHFSYPDG
CCCCCCCCCCCCCHHHHHCCHHHCCCCCCCCHHHHEECEEECCCCCCCCEEEEEECCCCC
YGMMKLAKKWEVPLVISALGTIERKVAYEGSYTSKQIIEAMNFADRILSVSEDLKTHIVN
CCHHHHHHHCCCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEE
LGIDENKVDVVPNGVDTEIFRPAGKEYARNVLNLPQEKKIVLFIGALRKIKGVDYLIEAA
CCCCCCCEEECCCCCCCHHHCCCCHHHHHHHHCCCCCCEEEEEEEHHHHHCCHHHHHHHH
KSFVNKNTDLYMVGRDDGLRKSLEKRAEELKISGFIKFTGPVTHEEIPLWISAADMLVLP
HHHHCCCCCEEEEECCHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCEEEEECCEEEEC
SLSEGRPNVVLEALSCEVPVVATDVGGIPELMVEGETGYLVPSKNPVQLSEKINKLLENE
CCCCCCCCEEEEECCCCCCEEEECCCCCCCEEEECCCCEECCCCCCHHHHHHHHHHHHCH
SRREKMGKFGRKSIIQRGLTWESHAKKTVDIYSELLARSSK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRVLEVCQEFPNRYYPQLGTFIKQSIDSIANQGVELTVISPKAFVLPFSAFPYHNFSKLP
CCHHHHHHHCCHHHCHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCCCCCCHHHCC
GIEHTEKYDLHFPRYFYAVPKKYFYPLTGMSYSYFVSGYAMKNINPKPELIHAHFSYPDG
CCCCCCCCCCCCCHHHHHCCHHHCCCCCCCCHHHHEECEEECCCCCCCCEEEEEECCCCC
YGMMKLAKKWEVPLVISALGTIERKVAYEGSYTSKQIIEAMNFADRILSVSEDLKTHIVN
CCHHHHHHHCCCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEE
LGIDENKVDVVPNGVDTEIFRPAGKEYARNVLNLPQEKKIVLFIGALRKIKGVDYLIEAA
CCCCCCCEEECCCCCCCHHHCCCCHHHHHHHHCCCCCCEEEEEEEHHHHHCCHHHHHHHH
KSFVNKNTDLYMVGRDDGLRKSLEKRAEELKISGFIKFTGPVTHEEIPLWISAADMLVLP
HHHHCCCCCEEEEECCHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCEEEEECCEEEEC
SLSEGRPNVVLEALSCEVPVVATDVGGIPELMVEGETGYLVPSKNPVQLSEKINKLLENE
CCCCCCCCEEEEECCCCCCEEEECCCCCCCEEEECCCCEECCCCCCHHHHHHHHHHHHCH
SRREKMGKFGRKSIIQRGLTWESHAKKTVDIYSELLARSSK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA