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The map label for this gene is pqqE [H]

Identifier: 21227207

GI number: 21227207

Start: 1298445

End: 1299635

Strand: Direct

Name: pqqE [H]

Synonym: MM_1105

Alternate gene names: 21227207

Gene position: 1298445-1299635 (Clockwise)

Preceding gene: 21227206

Following gene: 21227210

Centisome position: 31.7

GC content: 46.77

Gene sequence:

>1191_bases
TTGAACAACACGGAAAATAAAAGCCACCAGAAATCCAGATGCAGGGAAAATATGCAATACGAGTTTTACAAAAATCCCCT
TTTCAGGGTTTATGCCGAAATTGAAGACGGATGCCTTGCGATGAAAACAGGCGGGGCAGTCTCTCCACTGATGAAAAACG
TCCTTAAGGCAAATATCTCAATCTTTAACGGCGAAAAGCCTGCAAGAATAGAGGCTGACCGCCTGATCTATTCTACATGG
ATGCCCCCGATCCCGAGTTCTGGCTTTGACCGCCTTGTTAAAAGCCAGCTTTCATCAATGATAGGGAAAAACATTCCCGA
CCAGGTAACAATCTCGATTACAGAGGACTGCCCCAACAACTGCATCCACTGTGCCCTTCCTGATACGAAGAACAGAGCGA
AACTTTCACCTGAAACAGTCAGGGATGTGATCGACCAGGTTCTCGAAATGGGTACGACCTTTGTTATCTTTGACGGGGGA
GAACCTCTGACATATCCAGGTCTGGAAGAGCTTATAAGCTACGTTGACCCTGAAAAAGCCATTACCGGAATGTTCACTTC
CGGGGTTGGGCTGACAGAAGAACGCGCAAGGAGCCTCAAGGCTGCAGGGCTTTACTCTCTTACGGTCAGTTTTGACAGCG
CATATGAAGAAAAACACGACTATGTAAGGGGCAGGAAGGGAGTATTCAAAAGCGCGGTTGAAGCAGTTAAAAATGGGCTT
GCTGCAGGGCTGCTTGTAAATATATACGTGGTGCTCTCACGGGACAATGTCAATGAACTTGATGAGCTTTATAACCTTGC
AGCAGGCCTCGGAGCCCATGAACTCTCTTTCTATGAGATAGTGCCTACAGGCAGGTGGATGGACCACGCCTCCGAAATAA
TGACCCCAAAGGATATGAGAAAATTTGATAACTTTGTGGTTCAGGCACACGAAAAAGAAGGCCCGAGAATTTTTCCGATT
CCGCTGGTTATGAGGACAACAGGCTGTATGGCAGGCAGGAAATGGCTGCATATCACGCCAGAAGGAAACATTCTGCCCTG
CGCATGTATCCCCATTCCTTACGGGAATGTCCACAAAGACAGGGTGAAGGATATCTGGAAAAAAATCAGGAAAGACCCCG
CATATAATGCAAAATGCTGCCTTATGAGGAATCCGGAGTTCAGAGAGAAATATCTGAAACTTCCAGAATGA

Upstream 100 bases:

>100_bases
AAACTAACAAAAACATAAATCAACGAAAGAAGTAAACAAAAGCTAAGGCGCTGAAAAGAAGTACCCGGAACTACTGAAAA
AGAAGAACTGAAACATGTAA

Downstream 100 bases:

>100_bases
GCTTCAGACTCAAAGCAAATTTTGAATTTTTCGAGCAGGCAGGGTAAAAAAGTCGAAGCGGCAAAAGGCAAAACTGGAAG
CCAGAAAACAGGAATTCCTT

Product: metallo cofactor biosynthesis protein

Products: NA

Alternate protein names: Pyrroloquinoline quinone biosynthesis protein E [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNNTENKSHQKSRCRENMQYEFYKNPLFRVYAEIEDGCLAMKTGGAVSPLMKNVLKANISIFNGEKPARIEADRLIYSTW
MPPIPSSGFDRLVKSQLSSMIGKNIPDQVTISITEDCPNNCIHCALPDTKNRAKLSPETVRDVIDQVLEMGTTFVIFDGG
EPLTYPGLEELISYVDPEKAITGMFTSGVGLTEERARSLKAAGLYSLTVSFDSAYEEKHDYVRGRKGVFKSAVEAVKNGL
AAGLLVNIYVVLSRDNVNELDELYNLAAGLGAHELSFYEIVPTGRWMDHASEIMTPKDMRKFDNFVVQAHEKEGPRIFPI
PLVMRTTGCMAGRKWLHITPEGNILPCACIPIPYGNVHKDRVKDIWKKIRKDPAYNAKCCLMRNPEFREKYLKLPE

Sequences:

>Translated_396_residues
MNNTENKSHQKSRCRENMQYEFYKNPLFRVYAEIEDGCLAMKTGGAVSPLMKNVLKANISIFNGEKPARIEADRLIYSTW
MPPIPSSGFDRLVKSQLSSMIGKNIPDQVTISITEDCPNNCIHCALPDTKNRAKLSPETVRDVIDQVLEMGTTFVIFDGG
EPLTYPGLEELISYVDPEKAITGMFTSGVGLTEERARSLKAAGLYSLTVSFDSAYEEKHDYVRGRKGVFKSAVEAVKNGL
AAGLLVNIYVVLSRDNVNELDELYNLAAGLGAHELSFYEIVPTGRWMDHASEIMTPKDMRKFDNFVVQAHEKEGPRIFPI
PLVMRTTGCMAGRKWLHITPEGNILPCACIPIPYGNVHKDRVKDIWKKIRKDPAYNAKCCLMRNPEFREKYLKLPE
>Mature_396_residues
MNNTENKSHQKSRCRENMQYEFYKNPLFRVYAEIEDGCLAMKTGGAVSPLMKNVLKANISIFNGEKPARIEADRLIYSTW
MPPIPSSGFDRLVKSQLSSMIGKNIPDQVTISITEDCPNNCIHCALPDTKNRAKLSPETVRDVIDQVLEMGTTFVIFDGG
EPLTYPGLEELISYVDPEKAITGMFTSGVGLTEERARSLKAAGLYSLTVSFDSAYEEKHDYVRGRKGVFKSAVEAVKNGL
AAGLLVNIYVVLSRDNVNELDELYNLAAGLGAHELSFYEIVPTGRWMDHASEIMTPKDMRKFDNFVVQAHEKEGPRIFPI
PLVMRTTGCMAGRKWLHITPEGNILPCACIPIPYGNVHKDRVKDIWKKIRKDPAYNAKCCLMRNPEFREKYLKLPE

Specific function: Together With Moac, Is Involved In The Conversion Of A Guanosine Derivative (Gxp) Into Molybdopterin Precursor Z. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. PqqE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR000385
- InterPro:   IPR017200
- InterPro:   IPR011843
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 44581; Mature: 44581

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNTENKSHQKSRCRENMQYEFYKNPLFRVYAEIEDGCLAMKTGGAVSPLMKNVLKANIS
CCCCCCCHHHHHHHHHCCCHHHHCCCHHEEEEHHCCCEEEEECCCCHHHHHHHHHHHCCE
IFNGEKPARIEADRLIYSTWMPPIPSSGFDRLVKSQLSSMIGKNIPDQVTISITEDCPNN
EECCCCCCEECHHHEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
CIHCALPDTKNRAKLSPETVRDVIDQVLEMGTTFVIFDGGEPLTYPGLEELISYVDPEKA
CEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHCCHHHH
ITGMFTSGVGLTEERARSLKAAGLYSLTVSFDSAYEEKHDYVRGRKGVFKSAVEAVKNGL
HHHHHHCCCCCCHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGLLVNIYVVLSRDNVNELDELYNLAAGLGAHELSFYEIVPTGRWMDHASEIMTPKDMR
HHHEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCHHHHH
KFDNFVVQAHEKEGPRIFPIPLVMRTTGCMAGRKWLHITPEGNILPCACIPIPYGNVHKD
HHHHHHEEEECCCCCEEEECHHHHHHHHHHCCCCEEEECCCCCEEEEEEEECCCCCCCHH
RVKDIWKKIRKDPAYNAKCCLMRNPEFREKYLKLPE
HHHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCC
>Mature Secondary Structure
MNNTENKSHQKSRCRENMQYEFYKNPLFRVYAEIEDGCLAMKTGGAVSPLMKNVLKANIS
CCCCCCCHHHHHHHHHCCCHHHHCCCHHEEEEHHCCCEEEEECCCCHHHHHHHHHHHCCE
IFNGEKPARIEADRLIYSTWMPPIPSSGFDRLVKSQLSSMIGKNIPDQVTISITEDCPNN
EECCCCCCEECHHHEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
CIHCALPDTKNRAKLSPETVRDVIDQVLEMGTTFVIFDGGEPLTYPGLEELISYVDPEKA
CEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHCCHHHH
ITGMFTSGVGLTEERARSLKAAGLYSLTVSFDSAYEEKHDYVRGRKGVFKSAVEAVKNGL
HHHHHHCCCCCCHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGLLVNIYVVLSRDNVNELDELYNLAAGLGAHELSFYEIVPTGRWMDHASEIMTPKDMR
HHHEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCHHHHH
KFDNFVVQAHEKEGPRIFPIPLVMRTTGCMAGRKWLHITPEGNILPCACIPIPYGNVHKD
HHHHHHEEEECCCCCEEEECHHHHHHHHHHCCCCEEEECCCCCEEEEEEEECCCCCCCHH
RVKDIWKKIRKDPAYNAKCCLMRNPEFREKYLKLPE
HHHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11111029 [H]