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The map label for this gene is mtd [H]

Identifier: 21227210

GI number: 21227210

Start: 1301932

End: 1302771

Strand: Direct

Name: mtd [H]

Synonym: MM_1108

Alternate gene names: 21227210

Gene position: 1301932-1302771 (Clockwise)

Preceding gene: 21227207

Following gene: 21227213

Centisome position: 31.78

GC content: 48.1

Gene sequence:

>840_bases
TTGAAAAAAATGGTCAACATAGGCTTTATAAAAATGGGCAACCTGGGAATGAGCCAGGTTATTAATCTGATCCAGGATGA
AATTGCAGCACGAGAAGGAATCACCGTAAGAGTATTTGGTACCGGTGCTAAAATGGCTCCTGCCGATGCTGCAGACACTG
AAAGCTTCAAGCAGTGGAATGCTGACTTCGTGGTAATTATCAGCCCGAACGCAGCAGCTCCAGGACCTACCGCAGCCCGT
GAAATCTGGAAAGATGTACCCTGCATCATAGTTTCAGACGGCCCTACGAAAAAAGAAGCTCGTGAGGCTTTTGAGCAGGA
AGGTTTCGGATACATTATCCTGCCGGTAGATCCCCTTATCGGAGCAAAGAGGGAGTTCCTTGACTCTGTCGAGATGGCAT
CCTTTAACGCCGACGCTATGAAAGTGCTTTCCATCTGTGGTGTTGTAAGACTTATCCAGGAAGAACTTGACAAAGTGACA
GAACAGGTCGCATCCGGAAAGTCAGGAAAGGACCTGGAACTCCCGCACATTTTCGCTAAACCCGAGAAATGTGTCGAACA
TGCAGGCTTTGCAAACCCCTATGCAAAGTCAAAAGCTCTTGCTGCCCTTCACATGGCTGAAAAGGTTGCTCAGGTCAACT
TCCCTGCTTGCTTCATGTTGAAGGAAATCGAGCAGGTATGCCTTACAGCCGCAGCCGGACATGAGATTATGGGAGCTGCA
GCACAGCTCGCAAACCAGGCAAGAGAAATAGAGAAATCCAATGACACCGTCTCCAGGATGCCCCATGCAAAGAACGGAGC
CGTGTTGAAAAAAGTCAGGTTATATGAAAAGCCAGAGTAA

Upstream 100 bases:

>100_bases
TAGATATATATAAAATAAAGGTGATAAGGGAAGGAAATTGCCAAAAGGATTATAAACCCTTTGGGAATTCCACTATTGAG
AAAAAGGTCAACACAGGATT

Downstream 100 bases:

>100_bases
TTCTGGAAAAAATATCATTTGTGAAATAACCTGTTATTATTTCTGAAATAAACCTGTTATTAAAACTGGAGGGACTGAAA
AGATGTCCCTCTCAATTAAA

Product: F420-dependent methylenetetrahydromethanopterin dehydrogenase

Products: NA

Alternate protein names: MTD; Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKKMVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWNADFVVIISPNAAAPGPTAAR
EIWKDVPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLIGAKREFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVT
EQVASGKSGKDLELPHIFAKPEKCVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAA
AQLANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE

Sequences:

>Translated_279_residues
MKKMVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWNADFVVIISPNAAAPGPTAAR
EIWKDVPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLIGAKREFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVT
EQVASGKSGKDLELPHIFAKPEKCVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAA
AQLANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE
>Mature_279_residues
MKKMVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWNADFVVIISPNAAAPGPTAAR
EIWKDVPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLIGAKREFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVT
EQVASGKSGKDLELPHIFAKPEKCVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAA
AQLANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE

Specific function: Catalyzes the reversible reduction of methenyl- H(4)MPT(+) to methylene-H(4)MPT [H]

COG id: COG1927

COG function: function code C; Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002844
- ProDom:   PD017604 [H]

Pfam domain/function: PF01993 MTD [H]

EC number: =1.5.99.9 [H]

Molecular weight: Translated: 30240; Mature: 30240

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWN
CCCCEEECEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHCC
ADFVVIISPNAAAPGPTAAREIWKDVPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLI
CCEEEEECCCCCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHH
GAKREFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAK
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCC
PEKCVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
AQLANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE
HHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MKKMVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWN
CCCCEEECEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHCC
ADFVVIISPNAAAPGPTAAREIWKDVPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLI
CCEEEEECCCCCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHH
GAKREFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAK
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCC
PEKCVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
AQLANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE
HHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]