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The map label for this gene is fixC [C]

Identifier: 21227206

GI number: 21227206

Start: 1297177

End: 1298334

Strand: Direct

Name: fixC [C]

Synonym: MM_1104

Alternate gene names: 21227206

Gene position: 1297177-1298334 (Clockwise)

Preceding gene: 21227205

Following gene: 21227207

Centisome position: 31.67

GC content: 47.67

Gene sequence:

>1158_bases
ATGGACGCAGATATAATTGTAATCGGTGCATCTCCTGCAGGGCTCATGGCCGCCAGAAATGCCTGTGAAAAAGGTGTGGA
TGTGCTTTTGCTCGAAAGGAAAAAAGAGATAGGGAATCCACCCCACCCTGCAAATTCTTTTTTTAAGGGAATGCTTGACA
GGTGCGGAGAAAAGGCAGACGCATCTTATGTTGTTCACCACCTCAAAGGGATGAAAATCATCTCCCCGGAAGGACACGAA
GTAATAGTGGAAACTCCCGGCTATTCCATTGACAAGACAAAGTTTGACCGGTTTTATGCAGAGAAAGCCGCTAAAATCGG
TGTTGATATCAGGACAGGAATCGAAGCAAAGGATATCTGGAGAGAAGGAAAGGAATTTGCTGTTAGCACTTCTGCCGGGA
GGTTCAGGTCGAAACTTGTAATAATTTCTGACGGCATCAATTCGAAAATGGCTTCTCTTCTGGGTTTGAAAACAATGAAA
TACCCTGAAGATATAGCCTGGGGAACCGAGCTGGACATAAGAGCTTCAGGACTGGGCAAACCTGAAATGTTTGAGTATTA
TGTCGGGAACCATGCCCCTGGCTGGAAAACGACATATGCGCCCAGGGGAGGCAATAACGCAGCTATCGGTGCTTATGTGC
GCAGGTGCGGAAAGGACGCGACCCCTTACCTGGATGCATGGGTCGAGCGTTTTAAAAAGCTTAAAGGGCTTGAAGAAATA
GAGGTTGTCAGAAAACTTTCCGGAGGAGACCCTATCGTAACCATACCCGGGGAGTATATAAGGGATGGAATAATGGTGGT
TGGAGGAGCTGCAGGCCAGTCCGGGATAGGATATGCCATGAGGGCAGGCCAGATATGCGGGGACGTGGCAGCGGATGCCG
TAAAGAAAGGTGAGGTCTCAAAAAGTGTTCTCTCGGAATACAGGAAAACCTGGGAAAAGGAATTCAGGGCAGAGCACTAC
GTGGGCCGTATAGGGCTTGAGACTCTCAGGAAGATGACTGATAGGGAAATCGATGAGATGGCAGAAATATTTGAAAACGA
AGACCTCTCCTTTATCCACGGCAGCGCTTTTGAACAGGCTATGCAGGTTTTTACGTTCATGTTGAAGAAGAAGCCTTCAG
CCATGCTCAGGTACGGGGCATTTCTGAGAAACAAATAA

Upstream 100 bases:

>100_bases
ATGTTCGGGTCAATGATTCTGGATGTTGTGCTCTGCATATATATTGGGTCTTATACCTCCATACTCTGGTAAAAATCCCT
GTTGGGAAGGATAGAAAAAA

Downstream 100 bases:

>100_bases
ACAGCAAAATAAACTAACAAAAACATAAATCAACGAAAGAAGTAAACAAAAGCTAAGGCGCTGAAAAGAAGTACCCGGAA
CTACTGAAAAAGAAGAACTG

Product: oxidoreductase

Products: NA

Alternate protein names: DGGGPL reductase 1; 2,3-di-O-geranylgeranylglyceryl phosphate reductase 1; Geranylgeranyl reductase 1; GGR 1 [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MDADIIVIGASPAGLMAARNACEKGVDVLLLERKKEIGNPPHPANSFFKGMLDRCGEKADASYVVHHLKGMKIISPEGHE
VIVETPGYSIDKTKFDRFYAEKAAKIGVDIRTGIEAKDIWREGKEFAVSTSAGRFRSKLVIISDGINSKMASLLGLKTMK
YPEDIAWGTELDIRASGLGKPEMFEYYVGNHAPGWKTTYAPRGGNNAAIGAYVRRCGKDATPYLDAWVERFKKLKGLEEI
EVVRKLSGGDPIVTIPGEYIRDGIMVVGGAAGQSGIGYAMRAGQICGDVAADAVKKGEVSKSVLSEYRKTWEKEFRAEHY
VGRIGLETLRKMTDREIDEMAEIFENEDLSFIHGSAFEQAMQVFTFMLKKKPSAMLRYGAFLRNK

Sequences:

>Translated_385_residues
MDADIIVIGASPAGLMAARNACEKGVDVLLLERKKEIGNPPHPANSFFKGMLDRCGEKADASYVVHHLKGMKIISPEGHE
VIVETPGYSIDKTKFDRFYAEKAAKIGVDIRTGIEAKDIWREGKEFAVSTSAGRFRSKLVIISDGINSKMASLLGLKTMK
YPEDIAWGTELDIRASGLGKPEMFEYYVGNHAPGWKTTYAPRGGNNAAIGAYVRRCGKDATPYLDAWVERFKKLKGLEEI
EVVRKLSGGDPIVTIPGEYIRDGIMVVGGAAGQSGIGYAMRAGQICGDVAADAVKKGEVSKSVLSEYRKTWEKEFRAEHY
VGRIGLETLRKMTDREIDEMAEIFENEDLSFIHGSAFEQAMQVFTFMLKKKPSAMLRYGAFLRNK
>Mature_385_residues
MDADIIVIGASPAGLMAARNACEKGVDVLLLERKKEIGNPPHPANSFFKGMLDRCGEKADASYVVHHLKGMKIISPEGHE
VIVETPGYSIDKTKFDRFYAEKAAKIGVDIRTGIEAKDIWREGKEFAVSTSAGRFRSKLVIISDGINSKMASLLGLKTMK
YPEDIAWGTELDIRASGLGKPEMFEYYVGNHAPGWKTTYAPRGGNNAAIGAYVRRCGKDATPYLDAWVERFKKLKGLEEI
EVVRKLSGGDPIVTIPGEYIRDGIMVVGGAAGQSGIGYAMRAGQICGDVAADAVKKGEVSKSVLSEYRKTWEKEFRAEHY
VGRIGLETLRKMTDREIDEMAEIFENEDLSFIHGSAFEQAMQVFTFMLKKKPSAMLRYGAFLRNK

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786227, Length=352, Percent_Identity=24.7159090909091, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011777
- InterPro:   IPR002938
- InterPro:   IPR016040
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: NA

Molecular weight: Translated: 42509; Mature: 42509

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDADIIVIGASPAGLMAARNACEKGVDVLLLERKKEIGNPPHPANSFFKGMLDRCGEKAD
CCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEHHHHCCCCCCCHHHHHHHHHHHCCCCCC
ASYVVHHLKGMKIISPEGHEVIVETPGYSIDKTKFDRFYAEKAAKIGVDIRTGIEAKDIW
HHHHHHHHCCCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCHHHHH
REGKEFAVSTSAGRFRSKLVIISDGINSKMASLLGLKTMKYPEDIAWGTELDIRASGLGK
HCCCCEEEECCCCHHHEEEEEEECCCCHHHHHHHHHHHCCCCHHHCCCCCCEEEECCCCC
PEMFEYYVGNHAPGWKTTYAPRGGNNAAIGAYVRRCGKDATPYLDAWVERFKKLKGLEEI
CHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHH
EVVRKLSGGDPIVTIPGEYIRDGIMVVGGAAGQSGIGYAMRAGQICGDVAADAVKKGEVS
HHHHHHCCCCCEEECCHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHH
KSVLSEYRKTWEKEFRAEHYVGRIGLETLRKMTDREIDEMAEIFENEDLSFIHGSAFEQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHH
MQVFTFMLKKKPSAMLRYGAFLRNK
HHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDADIIVIGASPAGLMAARNACEKGVDVLLLERKKEIGNPPHPANSFFKGMLDRCGEKAD
CCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEHHHHCCCCCCCHHHHHHHHHHHCCCCCC
ASYVVHHLKGMKIISPEGHEVIVETPGYSIDKTKFDRFYAEKAAKIGVDIRTGIEAKDIW
HHHHHHHHCCCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCHHHHH
REGKEFAVSTSAGRFRSKLVIISDGINSKMASLLGLKTMKYPEDIAWGTELDIRASGLGK
HCCCCEEEECCCCHHHEEEEEEECCCCHHHHHHHHHHHCCCCHHHCCCCCCEEEECCCCC
PEMFEYYVGNHAPGWKTTYAPRGGNNAAIGAYVRRCGKDATPYLDAWVERFKKLKGLEEI
CHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHH
EVVRKLSGGDPIVTIPGEYIRDGIMVVGGAAGQSGIGYAMRAGQICGDVAADAVKKGEVS
HHHHHHCCCCCEEECCHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHH
KSVLSEYRKTWEKEFRAEHYVGRIGLETLRKMTDREIDEMAEIFENEDLSFIHGSAFEQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHH
MQVFTFMLKKKPSAMLRYGAFLRNK
HHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a quinone or similar compound as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]