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The map label for this gene is uppS [H]

Identifier: 21227185

GI number: 21227185

Start: 1275386

End: 1276060

Strand: Direct

Name: uppS [H]

Synonym: MM_1083

Alternate gene names: 21227185

Gene position: 1275386-1276060 (Clockwise)

Preceding gene: 21227184

Following gene: 21227186

Centisome position: 31.13

GC content: 45.48

Gene sequence:

>675_bases
ATGGACCTGCTTTCCTTTGGTCAGCCACTTTATGAGAGGTATCTGTCCTGGCAAATCACAAGGTCAGCTACAAAGATCCC
TGCACATGTGGCTCTTATTCTCAAAGAGGCCGACCTCCTCGAATATAAAGGGATTGAAAAACTCCTGACCGCGCTTCTTA
CATTCAGAAAGTTTAAGGTGGAACTCGTAAGCATTTATGTGGACATCCTGAAGGCTGACCAGACTATGAAAGCCGAGCTT
GCCTCAACTCTTGGTGAACAGCTGGAAGAAAGTTTTATGGGCCTTCCTTCCGGAACAGGGTACGAAATATGCGGTCTTGA
GGGGGAAGTAAATTGCAGCCGGCAGGGCAAGGATTTTTTTGTATATCTGTCCCTTGGTTTTGGAGGGAGAGGGGAAATCA
CCAGGGCTGTAATTTCTATACTTGACGAAGTTAAGGCAGGGCGCATCAGGCCTGAAGAAGTTGACGAAAAAATGCTTGAA
TCACACCTCCTTGTTAAGCATGAGCCGGATATAATGATCCGTTCAGGAGGGCAGAAGCTTTCGGATTTCCTTGTCTGGCA
GTCCGTATATTCGGAACTGTATTTTACGGATGTTAACTGGAAAGATGTAAGGAAAATAGATCTCCTGAGAGTAATCAGGG
ACTTTCAGAAAAGACAGAGAAGGTACGGGAAATAA

Upstream 100 bases:

>100_bases
CGTAGAAAAGACCGGAAAAGCTCATGTCGGAAAAAACTGCCGGGTGAAATAAGAATTAAAAAAACACCGAATTTAAGGCT
TTATTCGGAAGGAATACTCA

Downstream 100 bases:

>100_bases
AGATGGAGTTTGGGGAAAGGACAGGAAGTCATTATGTTGTGGTTGTCTGCCCTAAATGCAGGCAGCATGCTCAGATAAGC
GAAACCGGAAAAAAGACTCT

Product: undecaprenyl pyrophosphate synthetase

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MDLLSFGQPLYERYLSWQITRSATKIPAHVALILKEADLLEYKGIEKLLTALLTFRKFKVELVSIYVDILKADQTMKAEL
ASTLGEQLEESFMGLPSGTGYEICGLEGEVNCSRQGKDFFVYLSLGFGGRGEITRAVISILDEVKAGRIRPEEVDEKMLE
SHLLVKHEPDIMIRSGGQKLSDFLVWQSVYSELYFTDVNWKDVRKIDLLRVIRDFQKRQRRYGK

Sequences:

>Translated_224_residues
MDLLSFGQPLYERYLSWQITRSATKIPAHVALILKEADLLEYKGIEKLLTALLTFRKFKVELVSIYVDILKADQTMKAEL
ASTLGEQLEESFMGLPSGTGYEICGLEGEVNCSRQGKDFFVYLSLGFGGRGEITRAVISILDEVKAGRIRPEEVDEKMLE
SHLLVKHEPDIMIRSGGQKLSDFLVWQSVYSELYFTDVNWKDVRKIDLLRVIRDFQKRQRRYGK
>Mature_224_residues
MDLLSFGQPLYERYLSWQITRSATKIPAHVALILKEADLLEYKGIEKLLTALLTFRKFKVELVSIYVDILKADQTMKAEL
ASTLGEQLEESFMGLPSGTGYEICGLEGEVNCSRQGKDFFVYLSLGFGGRGEITRAVISILDEVKAGRIRPEEVDEKMLE
SHLLVKHEPDIMIRSGGQKLSDFLVWQSVYSELYFTDVNWKDVRKIDLLRVIRDFQKRQRRYGK

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is probably the precursor of glycosyl carrier lipids [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786371, Length=105, Percent_Identity=40, Blast_Score=88, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 25734; Mature: 25734

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLSFGQPLYERYLSWQITRSATKIPAHVALILKEADLLEYKGIEKLLTALLTFRKFKV
CCCHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ELVSIYVDILKADQTMKAELASTLGEQLEESFMGLPSGTGYEICGLEGEVNCSRQGKDFF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCEEE
VYLSLGFGGRGEITRAVISILDEVKAGRIRPEEVDEKMLESHLLVKHEPDIMIRSGGQKL
EEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEECCCCEEEECCCHHH
SDFLVWQSVYSELYFTDVNWKDVRKIDLLRVIRDFQKRQRRYGK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLLSFGQPLYERYLSWQITRSATKIPAHVALILKEADLLEYKGIEKLLTALLTFRKFKV
CCCHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ELVSIYVDILKADQTMKAELASTLGEQLEESFMGLPSGTGYEICGLEGEVNCSRQGKDFF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCEEE
VYLSLGFGGRGEITRAVISILDEVKAGRIRPEEVDEKMLESHLLVKHEPDIMIRSGGQKL
EEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEECCCCEEEECCCHHH
SDFLVWQSVYSELYFTDVNWKDVRKIDLLRVIRDFQKRQRRYGK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]