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The map label for this gene is 21226180

Identifier: 21226180

GI number: 21226180

Start: 103957

End: 104409

Strand: Reverse

Name: 21226180

Synonym: MM_0078

Alternate gene names: NA

Gene position: 104409-103957 (Counterclockwise)

Preceding gene: 21226182

Following gene: 21226176

Centisome position: 2.55

GC content: 44.15

Gene sequence:

>453_bases
ATGAAGGCAGAAGCGAGAATTCGATTTCCTCTCTCAGTTGATATCAGCGGGAAAAAGGTGCTTATTGTAGATGACGTAAC
CGATACCGGAGATACCCTGAAGCTTTCTATCGGTTATGTGCAGAGCCTGAACGCTTCTGAAATCAGAACTGCGGTTCTGC
AGCACAAAACATGCTCTTCTTTTGTTCCGGATTTTTATGGCCAGAAGATCATCAGGTGGCGCTGGATCATTTATCCCTGG
GCTCGTTATGAGGATCTGGCAGGTTTTACCAAAAGGATTCTTGAAGATGGGGCTCTTGATGTCTCCCGGATAATATATGA
GCTTAAAGACAGGCATGGTCTTGAGGTAGGGGAAAAAGAAATCCTTGAAATACTGCATGACCTGGCTGAGAGAAAAGAGA
TCGAGAAAACTGAAGTGGATAATCTGGTTAAATGGCAGGTCAGGATGAAATAA

Upstream 100 bases:

>100_bases
AGGAAGGGGAGGATATGTCCCCGGAAGGCTGGTTTCTGACTTCCTGCTTTTCAGTGACCTGACCTCCATAAAGGTCGAAC
ACTATCTAAGAGGTGCTGAA

Downstream 100 bases:

>100_bases
AATAGTAAAATTGTTTTATCTGTCTTCCATGAAAGGTTTTTGCTTTTTAGCTGGCAAATCCTATGTTTTGTTCAATAAAC
CTTTACTTATTTTGAAAAAT

Product: xanthine-guanine phosphoribosyltransferase

Products: 5-phospho-alpha-D-ribose 1-diphosphate; xanthine

Alternate protein names: Xanthine-Guanine Phosphoribosyltransferase; Purine Phosphoribosyltransferase; Hypoxanthine/Guanine Phosphoribosyltransferase; Phosphoribosyl Transferase Domain Protein; Phosphoribosyl Transferase; Hypoxanthine-Guanine Phosphoribosyltransferase; Xanthine-Guanine Phosphoribosyltransferase Conjectural; Phosphoribosyltransferase-Like Protein; Phosphoribosyl Transferase Domain-Containing Protein; Purine Phosphoribosyltransferase Related Protein

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKAEARIRFPLSVDISGKKVLIVDDVTDTGDTLKLSIGYVQSLNASEIRTAVLQHKTCSSFVPDFYGQKIIRWRWIIYPW
ARYEDLAGFTKRILEDGALDVSRIIYELKDRHGLEVGEKEILEILHDLAERKEIEKTEVDNLVKWQVRMK

Sequences:

>Translated_150_residues
MKAEARIRFPLSVDISGKKVLIVDDVTDTGDTLKLSIGYVQSLNASEIRTAVLQHKTCSSFVPDFYGQKIIRWRWIIYPW
ARYEDLAGFTKRILEDGALDVSRIIYELKDRHGLEVGEKEILEILHDLAERKEIEKTEVDNLVKWQVRMK
>Mature_150_residues
MKAEARIRFPLSVDISGKKVLIVDDVTDTGDTLKLSIGYVQSLNASEIRTAVLQHKTCSSFVPDFYGQKIIRWRWIIYPW
ARYEDLAGFTKRILEDGALDVSRIIYELKDRHGLEVGEKEILEILHDLAERKEIEKTEVDNLVKWQVRMK

Specific function: Unknown

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.2.22

Molecular weight: Translated: 17434; Mature: 17434

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAEARIRFPLSVDISGKKVLIVDDVTDTGDTLKLSIGYVQSLNASEIRTAVLQHKTCSS
CCCCCEEECCEEEECCCCEEEEEECCCCCCCEEEEEECHHHCCCHHHHHHHHHHHHHHHH
FVPDFYGQKIIRWRWIIYPWARYEDLAGFTKRILEDGALDVSRIIYELKDRHGLEVGEKE
CCCHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHH
ILEILHDLAERKEIEKTEVDNLVKWQVRMK
HHHHHHHHHHHHHCCHHHHHHEEEEEEECC
>Mature Secondary Structure
MKAEARIRFPLSVDISGKKVLIVDDVTDTGDTLKLSIGYVQSLNASEIRTAVLQHKTCSS
CCCCCEEECCEEEECCCCEEEEEECCCCCCCEEEEEECHHHCCCHHHHHHHHHHHHHHHH
FVPDFYGQKIIRWRWIIYPWARYEDLAGFTKRILEDGALDVSRIIYELKDRHGLEVGEKE
CCCHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHH
ILEILHDLAERKEIEKTEVDNLVKWQVRMK
HHHHHHHHHHHHHCCHHHHHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 9-(5-phospho-beta-D-ribosyl)xanthine; diphosphate

Specific reaction: 9-(5-phospho-beta-D-ribosyl)xanthine + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA