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The map label for this gene is ThrC2 [H]

Identifier: 20808964

GI number: 20808964

Start: 2511829

End: 2512884

Strand: Reverse

Name: ThrC2 [H]

Synonym: TTE2619

Alternate gene names: 20808964

Gene position: 2512884-2511829 (Counterclockwise)

Preceding gene: 20808965

Following gene: 20808963

Centisome position: 93.44

GC content: 43.94

Gene sequence:

>1056_bases
ATGGCGTACGAAGGAATTATAAAAGCTTATAGAGAGTTTTTGCCTCCTATAAGAGATGAAAATATTGTCACGTTAAAAGA
GGGCAACACACCTTTAATTGAAGCTTTTAACCTCCAAAGAAAATATTTGCCGGGTATAAGGGTGTATCTAAAATACGAAG
GGCTAAATCCCACAGGTTCTTTTAAGGACAGGGGGATGACGGTAGCGGTATCTCAAGCAAAGCAAGAAGGGTCTAATGCC
GTCGTATGCGCCTCAACAGGCAACACTTCTGCTTCTGCAGCAGCCTATGCAGCAAAAGCAGGCCTTAAAAGTGTGGTATT
AATTCCTGGCGGTAAAATTGCTCTGGGGAAACTCGCACAGGCAATTGCTTATGGGGCAGAGGTTATTGCGGTAGATGGCA
ATTTTGATGACGCTTTAAGGCTTGTGAGAGAAATTTCGCAGAAATTCCCGATTACTTTGGTAAATTCTATAAACCCCTAT
CGCCTGGAAGGCCAAAAAACGGCAGCTTTTGAAATATGTGATGCTTTGGGAGAAGTACCAGACTATGTCTCTCTTCCTGT
GGGCAATGCAGGAAATATAACTGCTTACTGGATGGGATTTAAAGAATACTACCGGAAGGGGAAGATAAAAAAGCTTCCCA
AAATGCTTGGCTTTCAGGCGGCAGGAGCGGCTCCTATTGTGGAAGGAAGAGTAATAGAAAATCCCGAGACGATTGCCACG
GCTATAAGAATTGGCAACCCTGCCAGCTGGCAGAAGGCAGTGGCTGCAAGAGATGAGTCGGGGGGGATAATTGACAAAGT
TACGGATGAGGAAATACTGGAGGCTTATTCAATTTTGGCAAAAACAGAGGGGATTTTTGCAGAGCCAGCCTCTGCAGCCT
CCATAGCGGGTGTGATAAAGAAGTACAAAGAAGGATTTTTTAAAGAAGGAGATTCTGTGGTGTGTATCCTTACGGGGAAT
GGTTTAAAAGACCCTGATACTGCTGTTAAACTAGGGGGAGAGGTAAAGAGAATACAGCCAAATCTAAAGGAATTGGAGGA
AGTTTTGTATGGATAG

Upstream 100 bases:

>100_bases
ATTGCAAATACAGGTAAGGTTTTGGAAGCTTTAAAGGAGATAGAGGAGCTAAAGGAAGTAGAAAAAATAGAAAGTGTGAT
AAAAGTGAGGGAAGATTAAA

Downstream 100 bases:

>100_bases
TGACATGTCAGGCGGAATGGTAAAAGTGATGGTGCCGGCATCTACGGCTAATTTGGGCCCGGGTTTTGATGTGCTGGGTG
TGGCTTTGAACCTTTATACA

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MAYEGIIKAYREFLPPIRDENIVTLKEGNTPLIEAFNLQRKYLPGIRVYLKYEGLNPTGSFKDRGMTVAVSQAKQEGSNA
VVCASTGNTSASAAAYAAKAGLKSVVLIPGGKIALGKLAQAIAYGAEVIAVDGNFDDALRLVREISQKFPITLVNSINPY
RLEGQKTAAFEICDALGEVPDYVSLPVGNAGNITAYWMGFKEYYRKGKIKKLPKMLGFQAAGAAPIVEGRVIENPETIAT
AIRIGNPASWQKAVAARDESGGIIDKVTDEEILEAYSILAKTEGIFAEPASAASIAGVIKKYKEGFFKEGDSVVCILTGN
GLKDPDTAVKLGGEVKRIQPNLKELEEVLYG

Sequences:

>Translated_351_residues
MAYEGIIKAYREFLPPIRDENIVTLKEGNTPLIEAFNLQRKYLPGIRVYLKYEGLNPTGSFKDRGMTVAVSQAKQEGSNA
VVCASTGNTSASAAAYAAKAGLKSVVLIPGGKIALGKLAQAIAYGAEVIAVDGNFDDALRLVREISQKFPITLVNSINPY
RLEGQKTAAFEICDALGEVPDYVSLPVGNAGNITAYWMGFKEYYRKGKIKKLPKMLGFQAAGAAPIVEGRVIENPETIAT
AIRIGNPASWQKAVAARDESGGIIDKVTDEEILEAYSILAKTEGIFAEPASAASIAGVIKKYKEGFFKEGDSVVCILTGN
GLKDPDTAVKLGGEVKRIQPNLKELEEVLYG
>Mature_350_residues
AYEGIIKAYREFLPPIRDENIVTLKEGNTPLIEAFNLQRKYLPGIRVYLKYEGLNPTGSFKDRGMTVAVSQAKQEGSNAV
VCASTGNTSASAAAYAAKAGLKSVVLIPGGKIALGKLAQAIAYGAEVIAVDGNFDDALRLVREISQKFPITLVNSINPYR
LEGQKTAAFEICDALGEVPDYVSLPVGNAGNITAYWMGFKEYYRKGKIKKLPKMLGFQAAGAAPIVEGRVIENPETIATA
IRIGNPASWQKAVAARDESGGIIDKVTDEEILEAYSILAKTEGIFAEPASAASIAGVIKKYKEGFFKEGDSVVCILTGNG
LKDPDTAVKLGGEVKRIQPNLKELEEVLYG

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI2367138, Length=291, Percent_Identity=28.5223367697594, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508781, Length=294, Percent_Identity=23.469387755102, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 37629; Mature: 37497

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYEGIIKAYREFLPPIRDENIVTLKEGNTPLIEAFNLQRKYLPGIRVYLKYEGLNPTGS
CCHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEHHCCHHHHCCCEEEEEEEECCCCCCC
FKDRGMTVAVSQAKQEGSNAVVCASTGNTSASAAAYAAKAGLKSVVLIPGGKIALGKLAQ
CCCCCEEEEEEHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
AIAYGAEVIAVDGNFDDALRLVREISQKFPITLVNSINPYRLEGQKTAAFEICDALGEVP
HHHCCCEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCHHHHHHHHHHCCCC
DYVSLPVGNAGNITAYWMGFKEYYRKGKIKKLPKMLGFQAAGAAPIVEGRVIENPETIAT
CEEECCCCCCCCEEEEEECHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHH
AIRIGNPASWQKAVAARDESGGIIDKVTDEEILEAYSILAKTEGIFAEPASAASIAGVIK
EEECCCCHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
KYKEGFFKEGDSVVCILTGNGLKDPDTAVKLGGEVKRIQPNLKELEEVLYG
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCCCHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
AYEGIIKAYREFLPPIRDENIVTLKEGNTPLIEAFNLQRKYLPGIRVYLKYEGLNPTGS
CHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEHHCCHHHHCCCEEEEEEEECCCCCCC
FKDRGMTVAVSQAKQEGSNAVVCASTGNTSASAAAYAAKAGLKSVVLIPGGKIALGKLAQ
CCCCCEEEEEEHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
AIAYGAEVIAVDGNFDDALRLVREISQKFPITLVNSINPYRLEGQKTAAFEICDALGEVP
HHHCCCEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCHHHHHHHHHHCCCC
DYVSLPVGNAGNITAYWMGFKEYYRKGKIKKLPKMLGFQAAGAAPIVEGRVIENPETIAT
CEEECCCCCCCCEEEEEECHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHH
AIRIGNPASWQKAVAARDESGGIIDKVTDEEILEAYSILAKTEGIFAEPASAASIAGVIK
EEECCCCHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
KYKEGFFKEGDSVVCILTGNGLKDPDTAVKLGGEVKRIQPNLKELEEVLYG
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCCCHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]