Click here to switch to the map view.

The map label for this gene is CopZ [H]

Identifier: 20808821

GI number: 20808821

Start: 2356428

End: 2356652

Strand: Reverse

Name: CopZ [H]

Synonym: TTE2466

Alternate gene names: 20808821

Gene position: 2356652-2356428 (Counterclockwise)

Preceding gene: 20808822

Following gene: 20808820

Centisome position: 87.63

GC content: 36.0

Gene sequence:

>225_bases
ATGGGTTTGTTTGGACCTAAGGGTGAGACTATCGTCATAAATGTTAAGGGGATGACATGCAACCATTGCAAAATGTCTGT
TGAAAATGCACTAAAGAAGTTAAATGGGGTATTGAAAGCTGTTGTTGACCTTGATAAAGGTAATGTTACGGTAACATATG
ACCCTGCTAAAGTTTCTGTCGATGATATGAAAAAAGCAATTATTGATACAGGATATGAAGTGTAA

Upstream 100 bases:

>100_bases
GCCGACGTAGGTGTTGCACTCCTTGCAGTCCTTAATTCCTTAAGATTGCTTAATAAAAAATAAAAATATTATTAACTTTT
AAAAAAGGAGGATATGAATC

Downstream 100 bases:

>100_bases
TACCTATTAAAAAATTTAAAGTGTAAAGTAGGAGGATGTTTTGTGGAATTTGTGAAACATCGATGTTAACTTTTCTAAAT
AATTTGCAACTGACTAAGGA

Product: copper chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 74; Mature: 73

Protein sequence:

>74_residues
MGLFGPKGETIVINVKGMTCNHCKMSVENALKKLNGVLKAVVDLDKGNVTVTYDPAKVSVDDMKKAIIDTGYEV

Sequences:

>Translated_74_residues
MGLFGPKGETIVINVKGMTCNHCKMSVENALKKLNGVLKAVVDLDKGNVTVTYDPAKVSVDDMKKAIIDTGYEV
>Mature_73_residues
GLFGPKGETIVINVKGMTCNHCKMSVENALKKLNGVLKAVVDLDKGNVTVTYDPAKVSVDDMKKAIIDTGYEV

Specific function: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA) [H]

COG id: COG2608

COG function: function code P; Copper chaperone

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR000428
- InterPro:   IPR006122
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00403 HMA [H]

EC number: NA

Molecular weight: Translated: 7956; Mature: 7825

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLFGPKGETIVINVKGMTCNHCKMSVENALKKLNGVLKAVVDLDKGNVTVTYDPAKVSV
CCCCCCCCCEEEEEECCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
DDMKKAIIDTGYEV
HHHHHHHHCCCCCC
>Mature Secondary Structure 
GLFGPKGETIVINVKGMTCNHCKMSVENALKKLNGVLKAVVDLDKGNVTVTYDPAKVSV
CCCCCCCCEEEEEECCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
DDMKKAIIDTGYEV
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA