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The map label for this gene is hycH [H]

Identifier: 20808123

GI number: 20808123

Start: 1645910

End: 1646335

Strand: Reverse

Name: hycH [H]

Synonym: TTE1697

Alternate gene names: 20808123

Gene position: 1646335-1645910 (Counterclockwise)

Preceding gene: 20808124

Following gene: 20808122

Centisome position: 61.21

GC content: 38.5

Gene sequence:

>426_bases
ATGCCGGGTAAAGTAAAATTCTTTAAACTCTCCAAAAGGTTTGTGGACGAAAAAGATGCCCCTGCCGAAGTCGAACAGCT
AAAATACTATGCTTTAGCTATTGGTCACCATATAGGGATAGTTGATTGTTTGTCGCCTGTTATGACTATGGAAGAGAAAG
ACTATTTAGAATGGATCAGTAAATTCCCCCCAGGAAAGGTCAGAAGAAAATTGGAAGGCTTGACAAAATGGGGAGAAATC
GAGATAAATAGAGAACATGTTGCTTTGTTAGTGTCAACGTTATCCCAAGCTTTTCCTAGTTTTTTACCAGAAGAAAAAGA
ATGGGCTAACTGTTTGCTTAAGCTTCTCCATTCTATACAAAAAGAACCAGCTATATATGTGGTGGTGAGACTGAGTGAAG
AGAATAGTGATTACTGTAGGCAATGA

Upstream 100 bases:

>100_bases
GATCGCAAAATTAAAGAGTTGGTAAAACAACAAAAAGATCCACGATTGGCTGAAATTTTTTTAAGTTTGCACAAAATTTA
CATGGAAAGGGTAGGTCATG

Downstream 100 bases:

>100_bases
GATGATGGGGGATGATGGAGCTGGCCCATTATTGGCCCGGCTTTTAGAACAAAACCCTATACCTGGATGGCAGGTCATTG
ATGGTGGGTCGGTGCCTGAG

Product: formate hydrogenlyase maturation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MPGKVKFFKLSKRFVDEKDAPAEVEQLKYYALAIGHHIGIVDCLSPVMTMEEKDYLEWISKFPPGKVRRKLEGLTKWGEI
EINREHVALLVSTLSQAFPSFLPEEKEWANCLLKLLHSIQKEPAIYVVVRLSEENSDYCRQ

Sequences:

>Translated_141_residues
MPGKVKFFKLSKRFVDEKDAPAEVEQLKYYALAIGHHIGIVDCLSPVMTMEEKDYLEWISKFPPGKVRRKLEGLTKWGEI
EINREHVALLVSTLSQAFPSFLPEEKEWANCLLKLLHSIQKEPAIYVVVRLSEENSDYCRQ
>Mature_140_residues
PGKVKFFKLSKRFVDEKDAPAEVEQLKYYALAIGHHIGIVDCLSPVMTMEEKDYLEWISKFPPGKVRRKLEGLTKWGEIE
INREHVALLVSTLSQAFPSFLPEEKEWANCLLKLLHSIQKEPAIYVVVRLSEENSDYCRQ

Specific function: Seems to be required for the conversion of a precursor form of the large subunit of hydrogenlyase (hycE) into a mature form [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hyfJ [H]

Homologues:

Organism=Escherichia coli, GI1789073, Length=132, Percent_Identity=45.4545454545455, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI87082116, Length=129, Percent_Identity=34.1085271317829, Blast_Score=85, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010005
- ProDom:   PD021295 [H]

Pfam domain/function: PF07450 HycH [H]

EC number: NA

Molecular weight: Translated: 16336; Mature: 16205

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGKVKFFKLSKRFVDEKDAPAEVEQLKYYALAIGHHIGIVDCLSPVMTMEEKDYLEWIS
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KFPPGKVRRKLEGLTKWGEIEINREHVALLVSTLSQAFPSFLPEEKEWANCLLKLLHSIQ
HCCCHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
KEPAIYVVVRLSEENSDYCRQ
CCCEEEEEEEECCCCCHHCCC
>Mature Secondary Structure 
PGKVKFFKLSKRFVDEKDAPAEVEQLKYYALAIGHHIGIVDCLSPVMTMEEKDYLEWIS
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KFPPGKVRRKLEGLTKWGEIEINREHVALLVSTLSQAFPSFLPEEKEWANCLLKLLHSIQ
HCCCHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
KEPAIYVVVRLSEENSDYCRQ
CCCEEEEEEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]