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The map label for this gene is HtpX [H]

Identifier: 20807471

GI number: 20807471

Start: 994521

End: 995747

Strand: Reverse

Name: HtpX [H]

Synonym: TTE0991

Alternate gene names: 20807471

Gene position: 995747-994521 (Counterclockwise)

Preceding gene: 20807476

Following gene: 20807467

Centisome position: 37.02

GC content: 33.25

Gene sequence:

>1227_bases
ATGGAATTTGTAAAATTCAACAAGTTATGGTTTTTGCTCATTTTAATTGCAGGAATATTCTCTTTTTTGTACCTTTATTA
TACATTATTTCCTGGAAATATACCCCATGATGTCTACAAATACTTTTCCCCTGCTGAAATCGCAAAAGCTCAAAAATATC
ACAAAATAAACCGCTTAATCTATATAAGTTCTTTCATGGCGAAGGCATTATTTTTAATATGGTTTACCTTTGGAAGAGGA
TCCCTTTTGTTTTCAAGATATACAGAAAAAGTTTCTTGTGGAAAATATTATTTGAATGTCTTTTTATACTTCATGGCTTT
ATGGTTAATCTTAAGATTAATTTCTCTCCCCTTCAGTTTAATAAACCATTTCGTCCAGGTGGAATGGGGATTTTCCGTTC
AGACAATGGCCTCTTGGTGGAGTGACTATTTTAAAAGCAGTCTTTTAGATTTTATTTTTTCCTCCATTGGGGTACTGTTA
CTCTTTATATTTTTAAACAAATGGCCCATTACGTGGTGGATAGCCGCCTTTTTCTTCCTCACCGTCGTAATGTTTGCTCA
AATTTACATATATCCAAACTTCATAGCTCCAATGTTTAATAAATTCACCCCAATCAAAGACCTTAAGATAATAAATATGG
TACAAGAAATCTCTCGAAATGCAGGAATAAAAATAGATAAAATTCAAGAAATGGACGCAAGTAAACGCACAACGCTGGCA
AACGCTTATTTTTATGGTTTTGGCAGCACAAGTAAAATTGTGCTTTACGATACGCTACTAAAAAATTATCCAGATGATGA
AATAAAAGCGGTCATAGCCCATGAAGCAGGTCACTGGAAAGAAAATCATGTGCTAAAAAGCTTACTTATAGGTACAATCG
GACTTTTCATAGGACTTTACTTACTTAATATTTTTATTCACTCAAGTATTACAATTCATCCCAATATTAAAATAACTCCA
GCTGTGTTATCGGTAATATACTTGTTTATTTTGCTTATCAATTTTGACACAAATCCTATACAAAATTACATTTCAAGGCA
GATGGAAAAACAGGCTGATTTACTATCCGTTGAATTCCTTCACAGCAAAGAACCTGTTATAAAACTTCAAATTGACCTCG
CAAAAAGAAGTTTGTTGGACGTATCTCCTCCCCCTTTTATAGAATGGTTCTCTTACTCCCATCCCTCTACTATGCACAGG
ATTGAATTAGTAGAAAAAGCCAAATAA

Upstream 100 bases:

>100_bases
TGATATATACATTTTTTCAAAAAAGCAAACTGCTGGTACTACTTTCCTCTTTAATGATATATAATAATGTCAGATATCTT
TTTTGAAAGGACTGAAGAAA

Downstream 100 bases:

>100_bases
AAAGGAAGGCAGAATAGCCTCCCTTTTTACGAAGCCTTTTCTTTTTCTATAAGCTTGATTGCTCCAGGTCCACAATACCT
CACGCATACACCGCAACCTG

Product: Zn-dependent protease with chaperone function

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MEFVKFNKLWFLLILIAGIFSFLYLYYTLFPGNIPHDVYKYFSPAEIAKAQKYHKINRLIYISSFMAKALFLIWFTFGRG
SLLFSRYTEKVSCGKYYLNVFLYFMALWLILRLISLPFSLINHFVQVEWGFSVQTMASWWSDYFKSSLLDFIFSSIGVLL
LFIFLNKWPITWWIAAFFFLTVVMFAQIYIYPNFIAPMFNKFTPIKDLKIINMVQEISRNAGIKIDKIQEMDASKRTTLA
NAYFYGFGSTSKIVLYDTLLKNYPDDEIKAVIAHEAGHWKENHVLKSLLIGTIGLFIGLYLLNIFIHSSITIHPNIKITP
AVLSVIYLFILLINFDTNPIQNYISRQMEKQADLLSVEFLHSKEPVIKLQIDLAKRSLLDVSPPPFIEWFSYSHPSTMHR
IELVEKAK

Sequences:

>Translated_408_residues
MEFVKFNKLWFLLILIAGIFSFLYLYYTLFPGNIPHDVYKYFSPAEIAKAQKYHKINRLIYISSFMAKALFLIWFTFGRG
SLLFSRYTEKVSCGKYYLNVFLYFMALWLILRLISLPFSLINHFVQVEWGFSVQTMASWWSDYFKSSLLDFIFSSIGVLL
LFIFLNKWPITWWIAAFFFLTVVMFAQIYIYPNFIAPMFNKFTPIKDLKIINMVQEISRNAGIKIDKIQEMDASKRTTLA
NAYFYGFGSTSKIVLYDTLLKNYPDDEIKAVIAHEAGHWKENHVLKSLLIGTIGLFIGLYLLNIFIHSSITIHPNIKITP
AVLSVIYLFILLINFDTNPIQNYISRQMEKQADLLSVEFLHSKEPVIKLQIDLAKRSLLDVSPPPFIEWFSYSHPSTMHR
IELVEKAK
>Mature_408_residues
MEFVKFNKLWFLLILIAGIFSFLYLYYTLFPGNIPHDVYKYFSPAEIAKAQKYHKINRLIYISSFMAKALFLIWFTFGRG
SLLFSRYTEKVSCGKYYLNVFLYFMALWLILRLISLPFSLINHFVQVEWGFSVQTMASWWSDYFKSSLLDFIFSSIGVLL
LFIFLNKWPITWWIAAFFFLTVVMFAQIYIYPNFIAPMFNKFTPIKDLKIINMVQEISRNAGIKIDKIQEMDASKRTTLA
NAYFYGFGSTSKIVLYDTLLKNYPDDEIKAVIAHEAGHWKENHVLKSLLIGTIGLFIGLYLLNIFIHSSITIHPNIKITP
AVLSVIYLFILLINFDTNPIQNYISRQMEKQADLLSVEFLHSKEPVIKLQIDLAKRSLLDVSPPPFIEWFSYSHPSTMHR
IELVEKAK

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=342, Percent_Identity=27.4853801169591, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17505484, Length=360, Percent_Identity=25.5555555555556, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322577, Length=314, Percent_Identity=33.1210191082803, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI19922414, Length=319, Percent_Identity=27.8996865203762, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24654305, Length=276, Percent_Identity=21.7391304347826, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI78707252, Length=199, Percent_Identity=27.6381909547739, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI78707254, Length=199, Percent_Identity=27.6381909547739, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 47738; Mature: 47738

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCEEEEEEEHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure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CCCCCEEEEEEEHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]