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The map label for this gene is uppP

Identifier: 20807476

GI number: 20807476

Start: 1000204

End: 1001019

Strand: Reverse

Name: uppP

Synonym: TTE0996

Alternate gene names: 20807476

Gene position: 1001019-1000204 (Counterclockwise)

Preceding gene: 20807479

Following gene: 20807471

Centisome position: 37.22

GC content: 37.99

Gene sequence:

>816_bases
ATGAAAATGGAGCTACTGATCAAAGCCTTTATAATGGGCATCGTAGAGGGATTAACTGAGTTTCTTCCAATCTCATCCAC
TGGCCACCTCATAATCGTCGGAAGTTTTATCAAATTTACAGGAAAGTTTGCTACAATGTTCGAAATTGTAATTCAGCTGG
GAGCAATTTTAGCGGTAGTGTATTATTTTAAAGACAAAATTCTCTCCTCCCTTAAGGCTTTAAAGCCAGGAGAATGGGGA
TTTAATCTGTGGTATAAAACGTTCATAGCCTTTTTGCCTGCTGCGATAATTGGTATACTGACCCATCACTACATTGAAGA
ACATCTATTTTCTCCATTTACCGTAGCAATAGCCCTGATAGTAGGTGCAATAATGATGATAGTGATAGAAGATATATTCG
GCAAAAAGTATAAAATTGATAACATGGACAAAGTAAGCACTTCTAAAGCTTTCTGGATTGGAGTAGCCCAAGTGATGTCT
TTATTCCCAGGAATGTCAAGGTCTGCTTCCACTATAATGGGAGGAATGCTGGTAGGCCTATCAGTTAGAGCAGCTGCTGA
ATTTTCCTTTTTCTTGGCTATTCCCACAATGCTTGCTGCTACAGGCTTTGAACTTGTGAAAAACATTACCTCCATGTCAT
TACTAGAATGGGAAGCGCTGGCAGTAGGATTTATAATGTCCTTTATAACTGCTTTGATCGTAGTCGATAAATTTTTGGCC
TACCTCAAAAGGCATGTTTTAAAACCTTTTGCGTATTATAGACTCCTAGTTGGAGTGCTAATGTTATTCTTAATCGCCCA
AAAAATAGTAAAATAA

Upstream 100 bases:

>100_bases
AACAGATTAAATTTAGATTAAATTTACATTTTCTTGATTGATTCCTCCATCATTATCATATAAAATAGATAGAGGTGACA
AAAATTCTATATAAAGGGGT

Downstream 100 bases:

>100_bases
AAAGGATAGGTCAAACCGCCTATCCTTTTTATTTATCCAGCTCTTCATAAGCTTTTGAATACACTTCATAATCTCTATCG
CTGAAGAGAACAAATCTCAC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MKMELLIKAFIMGIVEGLTEFLPISSTGHLIIVGSFIKFTGKFATMFEIVIQLGAILAVVYYFKDKILSSLKALKPGEWG
FNLWYKTFIAFLPAAIIGILTHHYIEEHLFSPFTVAIALIVGAIMMIVIEDIFGKKYKIDNMDKVSTSKAFWIGVAQVMS
LFPGMSRSASTIMGGMLVGLSVRAAAEFSFFLAIPTMLAATGFELVKNITSMSLLEWEALAVGFIMSFITALIVVDKFLA
YLKRHVLKPFAYYRLLVGVLMLFLIAQKIVK

Sequences:

>Translated_271_residues
MKMELLIKAFIMGIVEGLTEFLPISSTGHLIIVGSFIKFTGKFATMFEIVIQLGAILAVVYYFKDKILSSLKALKPGEWG
FNLWYKTFIAFLPAAIIGILTHHYIEEHLFSPFTVAIALIVGAIMMIVIEDIFGKKYKIDNMDKVSTSKAFWIGVAQVMS
LFPGMSRSASTIMGGMLVGLSVRAAAEFSFFLAIPTMLAATGFELVKNITSMSLLEWEALAVGFIMSFITALIVVDKFLA
YLKRHVLKPFAYYRLLVGVLMLFLIAQKIVK
>Mature_271_residues
MKMELLIKAFIMGIVEGLTEFLPISSTGHLIIVGSFIKFTGKFATMFEIVIQLGAILAVVYYFKDKILSSLKALKPGEWG
FNLWYKTFIAFLPAAIIGILTHHYIEEHLFSPFTVAIALIVGAIMMIVIEDIFGKKYKIDNMDKVSTSKAFWIGVAQVMS
LFPGMSRSASTIMGGMLVGLSVRAAAEFSFFLAIPTMLAATGFELVKNITSMSLLEWEALAVGFIMSFITALIVVDKFLA
YLKRHVLKPFAYYRLLVGVLMLFLIAQKIVK

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=263, Percent_Identity=43.3460076045627, Blast_Score=191, Evalue=6e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_THETN (Q8RB29)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622647.1
- GeneID:   995800
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE0996
- NMPDR:   fig|273068.3.peg.462
- HOGENOM:   HBG391969
- OMA:   HDVIKTY
- ProtClustDB:   PRK00281
- BioCyc:   TTEN273068:TTE0996-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30138; Mature: 30138

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd00dcb0)-; HASH(0xcc43eec)-; HASH(0xd9e2810)-; HASH(0x406757b4)-; HASH(0xb2011b8)-; HASH(0xca78f78)-; HASH(0xc7a0054)-; HASH(0xdcf1784)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMELLIKAFIMGIVEGLTEFLPISSTGHLIIVGSFIKFTGKFATMFEIVIQLGAILAVV
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
YYFKDKILSSLKALKPGEWGFNLWYKTFIAFLPAAIIGILTHHYIEEHLFSPFTVAIALI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VGAIMMIVIEDIFGKKYKIDNMDKVSTSKAFWIGVAQVMSLFPGMSRSASTIMGGMLVGL
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
SVRAAAEFSFFLAIPTMLAATGFELVKNITSMSLLEWEALAVGFIMSFITALIVVDKFLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLKRHVLKPFAYYRLLVGVLMLFLIAQKIVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MKMELLIKAFIMGIVEGLTEFLPISSTGHLIIVGSFIKFTGKFATMFEIVIQLGAILAVV
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
YYFKDKILSSLKALKPGEWGFNLWYKTFIAFLPAAIIGILTHHYIEEHLFSPFTVAIALI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VGAIMMIVIEDIFGKKYKIDNMDKVSTSKAFWIGVAQVMSLFPGMSRSASTIMGGMLVGL
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
SVRAAAEFSFFLAIPTMLAATGFELVKNITSMSLLEWEALAVGFIMSFITALIVVDKFLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLKRHVLKPFAYYRLLVGVLMLFLIAQKIVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336