Click here to switch to the map view.

The map label for this gene is LysR2 [H]

Identifier: 20807467

GI number: 20807467

Start: 990753

End: 991637

Strand: Reverse

Name: LysR2 [H]

Synonym: TTE0987

Alternate gene names: 20807467

Gene position: 991637-990753 (Counterclockwise)

Preceding gene: 20807471

Following gene: 20807466

Centisome position: 36.87

GC content: 32.54

Gene sequence:

>885_bases
ATGAATTTACGCCAGCTAAAAATTTTTCTAACTGTATGCCAAGAAGGAAGCATGTCAAAGGCAGCCAAAAAACTGTACAT
GACTCAACCTTCCATAAGCCAGACTATAGGTGAATTAGAACAAGAGCTAAATATAAAATTGTTTGAAAGGATTAACAAAC
ATCTCTACCTCACTTATCCAGGCGAAATTTTAAGAGAATATTCAAAAAGAATAATCTCTTTACTTGAAGAAGCTGAAAAT
ACCCTCTTAGACATTTCAAATTTAAAAACTGGAAAACTTCGCGTAGGTGCAAGTACAACTATAGGAACTTATTTAATTCC
AAAAATACTCAGTGAGTTCCGCAAAAAATACGAAAATACCTCTATATTTTTTAATATTGACAACACAGCAGTAATAGAAA
AGCAAATTTTAGAAAATTCTATAGATATAGGAATTGTAGAAGGTCCCATTCATTCACAAGATATCATTATAGAACCTTTT
ATAGAAGATGAATTATACCTTGTATGTTCCAAAGGCCACAGATGGGCTTTAAAAAAAGTAATAGAGCCGTGGGAAATTGA
GGAGGAAGAATTAATTATTCGTGAAAAGGGAAGTGGCACAAGAGAAGTTTTTGAAACAATAATGTCCGCCAACAACTTAA
AATACCATATAAAACATGTACTTAACAATACAGAAGCCATAAAAAAAGCCGTTGAATTAAATATGGGCGTATCAGTTCTT
TCAAAACTTGCCGTATCAGAAGAGCTCAAAAAAGGCACCCTTGTAAAAATAGAAATAGAGGGTATAAAGTTCAAGAGAAT
GTTCAATATAATCTATCACAAGGATAAATACTTCTCCCCTACGTTTAAAGCTTTTATGGAGTATTTAAAGAGCGGTAGGA
GATAA

Upstream 100 bases:

>100_bases
AAATCACCTCACCACATTTTATATTGTAGCGATTGAACAACTATAAGTAAAATAGTATAATTTTATTAAATACATAAGCA
TATACTTATGAGGTGATTTT

Downstream 100 bases:

>100_bases
AATTAAAACAACCATCTTTGAAGGCCAAGAAATAGATTTAGATGTATTTAGCCATTAATGGGATTGACATAAGTATCCAA
TAAGGCTAAAATAAAGACAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MNLRQLKIFLTVCQEGSMSKAAKKLYMTQPSISQTIGELEQELNIKLFERINKHLYLTYPGEILREYSKRIISLLEEAEN
TLLDISNLKTGKLRVGASTTIGTYLIPKILSEFRKKYENTSIFFNIDNTAVIEKQILENSIDIGIVEGPIHSQDIIIEPF
IEDELYLVCSKGHRWALKKVIEPWEIEEEELIIREKGSGTREVFETIMSANNLKYHIKHVLNNTEAIKKAVELNMGVSVL
SKLAVSEELKKGTLVKIEIEGIKFKRMFNIIYHKDKYFSPTFKAFMEYLKSGRR

Sequences:

>Translated_294_residues
MNLRQLKIFLTVCQEGSMSKAAKKLYMTQPSISQTIGELEQELNIKLFERINKHLYLTYPGEILREYSKRIISLLEEAEN
TLLDISNLKTGKLRVGASTTIGTYLIPKILSEFRKKYENTSIFFNIDNTAVIEKQILENSIDIGIVEGPIHSQDIIIEPF
IEDELYLVCSKGHRWALKKVIEPWEIEEEELIIREKGSGTREVFETIMSANNLKYHIKHVLNNTEAIKKAVELNMGVSVL
SKLAVSEELKKGTLVKIEIEGIKFKRMFNIIYHKDKYFSPTFKAFMEYLKSGRR
>Mature_294_residues
MNLRQLKIFLTVCQEGSMSKAAKKLYMTQPSISQTIGELEQELNIKLFERINKHLYLTYPGEILREYSKRIISLLEEAEN
TLLDISNLKTGKLRVGASTTIGTYLIPKILSEFRKKYENTSIFFNIDNTAVIEKQILENSIDIGIVEGPIHSQDIIIEPF
IEDELYLVCSKGHRWALKKVIEPWEIEEEELIIREKGSGTREVFETIMSANNLKYHIKHVLNNTEAIKKAVELNMGVSVL
SKLAVSEELKKGTLVKIEIEGIKFKRMFNIIYHKDKYFSPTFKAFMEYLKSGRR

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=297, Percent_Identity=32.3232323232323, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI157672245, Length=283, Percent_Identity=25.0883392226148, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1788748, Length=293, Percent_Identity=24.9146757679181, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87082132, Length=293, Percent_Identity=27.9863481228669, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI145693105, Length=291, Percent_Identity=24.7422680412371, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87081904, Length=287, Percent_Identity=24.390243902439, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=23.8095238095238, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790399, Length=296, Percent_Identity=20.6081081081081, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789204, Length=294, Percent_Identity=23.1292517006803, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787530, Length=266, Percent_Identity=25.187969924812, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787806, Length=242, Percent_Identity=22.7272727272727, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=22.9838709677419, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788887, Length=245, Percent_Identity=25.7142857142857, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787879, Length=299, Percent_Identity=23.7458193979933, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787128, Length=304, Percent_Identity=23.3552631578947, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=176, Percent_Identity=24.4318181818182, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789639, Length=153, Percent_Identity=26.797385620915, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790262, Length=287, Percent_Identity=22.2996515679443, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=21.7687074829932, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789506, Length=198, Percent_Identity=23.7373737373737, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790208, Length=298, Percent_Identity=20.8053691275168, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367136, Length=148, Percent_Identity=31.0810810810811, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790011, Length=271, Percent_Identity=23.2472324723247, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789173, Length=290, Percent_Identity=22.7586206896552, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790783, Length=263, Percent_Identity=25.0950570342205, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788296, Length=248, Percent_Identity=26.6129032258064, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33983; Mature: 33983

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRQLKIFLTVCQEGSMSKAAKKLYMTQPSISQTIGELEQELNIKLFERINKHLYLTYP
CCHHHEEHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHCCCEEEECC
GEILREYSKRIISLLEEAENTLLDISNLKTGKLRVGASTTIGTYLIPKILSEFRKKYENT
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCC
SIFFNIDNTAVIEKQILENSIDIGIVEGPIHSQDIIIEPFIEDELYLVCSKGHRWALKKV
EEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCEEEEECCCCHHHHHHC
IEPWEIEEEELIIREKGSGTREVFETIMSANNLKYHIKHVLNNTEAIKKAVELNMGVSVL
CCCCCCCCHHEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCHHHH
SKLAVSEELKKGTLVKIEIEGIKFKRMFNIIYHKDKYFSPTFKAFMEYLKSGRR
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLRQLKIFLTVCQEGSMSKAAKKLYMTQPSISQTIGELEQELNIKLFERINKHLYLTYP
CCHHHEEHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHCCCEEEECC
GEILREYSKRIISLLEEAENTLLDISNLKTGKLRVGASTTIGTYLIPKILSEFRKKYENT
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCC
SIFFNIDNTAVIEKQILENSIDIGIVEGPIHSQDIIIEPFIEDELYLVCSKGHRWALKKV
EEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCEEEEECCCCHHHHHHC
IEPWEIEEEELIIREKGSGTREVFETIMSANNLKYHIKHVLNNTEAIKKAVELNMGVSVL
CCCCCCCCHHEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCHHHH
SKLAVSEELKKGTLVKIEIEGIKFKRMFNIIYHKDKYFSPTFKAFMEYLKSGRR
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]